Tomo Osako

Summary

Affiliation: Cancer Institute Hospital
Country: Japan

Publications

  1. pmc Incidence and possible pathogenesis of sentinel node micrometastases in ductal carcinoma in situ of the breast detected using molecular whole lymph node assay
    T Osako
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan
    Br J Cancer 106:1675-81. 2012
  2. doi request reprint Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: molecular whole-node analysis of all removed nodes
    Tomo Osako
    Division of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan
    Eur J Cancer 49:1187-95. 2013
  3. pmc Accurate staging of axillary lymph nodes from breast cancer patients using a novel molecular method
    T Osako
    Division of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, Tokyo, Japan
    Br J Cancer 105:1197-202. 2011
  4. doi request reprint Intraoperative molecular assay for sentinel lymph node metastases in early stage breast cancer: a comparative analysis between one-step nucleic acid amplification whole node assay and routine frozen section histology
    Tomo Osako
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
    Cancer 117:4365-74. 2011
  5. doi request reprint High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapy
    Tomo Osako
    Divisions of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo, 135 8550, Japan
    J Cancer Res Clin Oncol 136:1431-8. 2010
  6. doi request reprint Histogenesis of metaplastic breast carcinoma and axillary nodal metastases
    Tomo Osako
    Division of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake, Koto ku, Tokyo, Japan
    Pathol Int 59:116-20. 2009
  7. doi request reprint Predictive factors for efficacy of capecitabine in heavily pretreated patients with metastatic breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo, 135 8550, Japan
    Cancer Chemother Pharmacol 63:865-71. 2009
  8. doi request reprint Acute radiation dermatitis and pneumonitis in Japanese breast cancer patients with whole breast hypofractionated radiotherapy compared to conventional radiotherapy
    Tomo Osako
    Department of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo 135 8550, Japan
    Jpn J Clin Oncol 38:334-8. 2008
  9. ncbi request reprint Flare-up of dermatomyositis along with recurrence of breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan
    Breast J 13:200-2. 2007
  10. ncbi request reprint Diagnostic ultrasonography and mammography for invasive and noninvasive breast cancer in women aged 30 to 39 years
    Tomo Osako
    Department of Breast Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Japan
    Breast Cancer 14:229-33. 2007

Detail Information

Publications19

  1. pmc Incidence and possible pathogenesis of sentinel node micrometastases in ductal carcinoma in situ of the breast detected using molecular whole lymph node assay
    T Osako
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan
    Br J Cancer 106:1675-81. 2012
    ..In this retrospective cohort study, we determined the performance of the OSNA assay in DCIS and the pathogenesis of node-positive DCIS...
  2. doi request reprint Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: molecular whole-node analysis of all removed nodes
    Tomo Osako
    Division of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan
    Eur J Cancer 49:1187-95. 2013
    ..We aim to reveal the usefulness of the OSNA assay regarding the prediction of non-SN metastasis...
  3. pmc Accurate staging of axillary lymph nodes from breast cancer patients using a novel molecular method
    T Osako
    Division of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, Tokyo, Japan
    Br J Cancer 105:1197-202. 2011
    ..We aimed to determine the performance of the OSNA assay as an accurate nodal staging tool in comparison with routine histological examination...
  4. doi request reprint Intraoperative molecular assay for sentinel lymph node metastases in early stage breast cancer: a comparative analysis between one-step nucleic acid amplification whole node assay and routine frozen section histology
    Tomo Osako
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
    Cancer 117:4365-74. 2011
    ..The authors compared the performance in intraoperative detection of sentinel lymph node metastases with OSNA assay using a whole lymph node versus routine frozen section (FS) histology with a 2 mm-sectioned lymph node...
  5. doi request reprint High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapy
    Tomo Osako
    Divisions of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo, 135 8550, Japan
    J Cancer Res Clin Oncol 136:1431-8. 2010
    ..To determine the highly sensitive and highly resistant subsets to cytotoxic chemotherapy, we evaluated predictive factors for pCR and PD to NAC, and assessed the similarities in these factors...
  6. doi request reprint Histogenesis of metaplastic breast carcinoma and axillary nodal metastases
    Tomo Osako
    Division of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake, Koto ku, Tokyo, Japan
    Pathol Int 59:116-20. 2009
    ..This suggested that the ductal component metastasized to the nodes and that epithelial-mesenchymal transition subsequently occurred within the nodes...
  7. doi request reprint Predictive factors for efficacy of capecitabine in heavily pretreated patients with metastatic breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo, 135 8550, Japan
    Cancer Chemother Pharmacol 63:865-71. 2009
    ....
  8. doi request reprint Acute radiation dermatitis and pneumonitis in Japanese breast cancer patients with whole breast hypofractionated radiotherapy compared to conventional radiotherapy
    Tomo Osako
    Department of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo 135 8550, Japan
    Jpn J Clin Oncol 38:334-8. 2008
    ..To evaluate acute morbidity, radiation dermatitis and pneumonitis, of Japanese patients treated with whole breast hypofractionated radiotherapy (RT) after breast-conserving surgery (BCS), compared to conventional RT...
  9. ncbi request reprint Flare-up of dermatomyositis along with recurrence of breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan
    Breast J 13:200-2. 2007
    ....
  10. ncbi request reprint Diagnostic ultrasonography and mammography for invasive and noninvasive breast cancer in women aged 30 to 39 years
    Tomo Osako
    Department of Breast Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Japan
    Breast Cancer 14:229-33. 2007
    ....
  11. ncbi request reprint Intermittent capecitabine monotherapy with lower dose intensity in heavily pretreated patients with metastatic breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo
    Tumori 93:129-32. 2007
    ..The purpose of the present retrospective study was to evaluate efficacy and safety of a lower dose-intensity capecitabine monotherapy regimen in heavily pretreated patients with metastatic breast cancer...
  12. ncbi request reprint Diagnostic mammography and ultrasonography for palpable and nonpalpable breast cancer in women aged 30 to 39 years
    Tomo Osako
    Department of Breast Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake, Tokyo, Japan
    Breast Cancer 14:255-9. 2007
    ..To investigate the relationship between the tumor size of breast cancer by palpation and the sensitivity of mammography (MMG) and ultrasonography (US), and which modality can detect nonpalpable breast cancer in women aged 30 to 39 years...
  13. ncbi request reprint Efficacy and safety of trastuzumab plus capecitabine in heavily pretreated patients with HER2-positive metastatic breast cancer
    Tomo Osako
    Department of Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo 135 8550, Japan
    Cancer Chemother Pharmacol 62:159-64. 2008
    ..We retrospectively evaluated the efficacy and safety of combination therapy of trastuzumab plus capecitabine in heavily pretreated patients with HER2-positive metastatic breast cancer (MBC)...
  14. doi request reprint Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapy
    Tomo Osako
    Division of Pathology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo, 135 8550, Japan
    J Cancer Res Clin Oncol 136:233-41. 2010
    ....
  15. doi request reprint Detection of occult invasion in ductal carcinoma in situ of the breast with sentinel node metastasis
    Tomo Osako
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
    Cancer Sci 104:453-7. 2013
    ..Patient follow-up is required to elucidate the prognostic impact of nodal metastasis and occult invasion...
  16. doi request reprint Apocrine metaplasia of breast cancer: clinicopathological features and predicting response
    Akiko Ogiya
    Department of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Koto ku, Tokyo, Japan
    Breast Cancer 17:290-7. 2010
    ..We thus considered that apocrine metaplasia (AM) might represent a predictive marker for breast cancer...
  17. doi request reprint Clinicopathological significance of invasive micropapillary carcinoma component in invasive breast carcinoma
    Yoshimi Ide
    Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
    Pathol Int 61:731-6. 2011
    ..The presence of IMP components was a significant predictive factor for nodal metastasis, even if it is detected in only a small proportion of the tumor...
  18. doi request reprint Secretory carcinoma of the breast and its histopathological mimics: value of markers for differential diagnosis
    Tomo Osako
    Division of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan Department of Pathology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan
    Histopathology 63:509-19. 2013
    ..However, differential markers have not yet been assessed systematically, and we aimed to identify and evaluate novel and existing markers...
  19. ncbi request reprint Intraperitoneal rupture of the ureter as a cause of generalized peritonitis: report of a case
    Tomo Osako
    Department of Surgery, Ayabe Municipal Hospital, Kyoto, Japan
    Surg Today 36:839-42. 2006
    ..Image-guided interventions play a crucial role in the management of ureteral urine leaks after a correct diagnosis has been made...