Research Topics
Species | Futoshi AkiyamaSummaryAffiliation: Cancer Institute Hospital Country: Japan Publications
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Detail Information
Publications
Skin invasion and prognosis in node negative breast cancer: a retrospective studyKeiichiro Tada
Department of Breast Surgery, Cancer Institute Hospital, Tokyo, Japan
World J Surg Oncol 6:10. 2008..The impact of skin invasion in node negative breast cancer is uncertain...- Ductal carcinoma in situ and sentinel lymph node metastasis in breast cancerKeiichiro Tada
Department of Breast Surgery, Cancer Institute Hospital, Tokyo, Japan
World J Surg Oncol 8:6. 2010..The impact of sentinel lymph node biopsy on breast cancer mimicking ductal carcinoma in situ (DCIS) is a matter of debate... - Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 yearsNaoko Honma
Research Team for Geriatric Diseases, Tokyo Metropolitan Institute of Gerontology, Sakaecho 35 2, Itabashi ku, Tokyo 173 0015, Japan
Breast Cancer Res 11:R48. 2009..The aim of the present study is to elucidate whether there are any specific patterns in use of multiple exons 1 in elderly breast tissue... 
Therapeutic strategies for breast cancer based on histological typeFutoshi Akiyama
Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
Breast Cancer 16:168-72. 2009..Histological diagnosis is also significant from the viewpoint of drug sensitivity, and it is important to maintain the accuracy of histological diagnosis...- Triple negative breast cancer: clinicopathological characteristics and treatment strategiesFutoshi Akiyama
Department of Pathology, Cancer Institute, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
Breast Cancer 16:252-3. 2009..This special issue consists of five conference papers that have been agreed on by the speakers and the commentator of the symposium of the 16th Annual Meeting of the Japanese Breast Cancer Society in September 2008 in Osaka... - Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapyTomo Osako
Division of Pathology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo, 135 8550, Japan
J Cancer Res Clin Oncol 136:233-41. 2010.... - High-grade breast cancers include both highly sensitive and highly resistant subsets to cytotoxic chemotherapyTomo Osako
Divisions of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo, 135 8550, Japan
J Cancer Res Clin Oncol 136:1431-8. 2010..To determine the highly sensitive and highly resistant subsets to cytotoxic chemotherapy, we evaluated predictive factors for pCR and PD to NAC, and assessed the similarities in these factors... - Clinicopathologic study of 53 metaplastic breast carcinomas: their elements and prognostic implicationsRin Yamaguchi
Department of Pathology, Cancer Institute of Japanese Foundation for Cancer Research, Tokyo 135 8550, Japan
Hum Pathol 41:679-85. 2010..The presence of high-grade spindle cells in metaplastic breast carcinoma may indicate aggressive behavior... - Intraoperative molecular assay for sentinel lymph node metastases in early stage breast cancer: a comparative analysis between one-step nucleic acid amplification whole node assay and routine frozen section histologyTomo Osako
Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
Cancer 117:4365-74. 2011..The authors compared the performance in intraoperative detection of sentinel lymph node metastases with OSNA assay using a whole lymph node versus routine frozen section (FS) histology with a 2 mm-sectioned lymph node... - Reoperative sentinel lymph node biopsy for ipsilateral breast tumor recurrence after previous axillary lymph node dissection: report of a caseMasaya Hattori
Department of Breast Oncology, Cancer Institute Hospital of Japanese Foundation For Cancer Research, 3 10 6 Ariake, Koto ku, Tokyo, Japan
Surg Today 41:247-50. 2011.... - Malignant transformation of breast fibroadenoma to malignant phyllodes tumor: long-term outcome of 36 malignant phyllodes tumorsMakoto Abe
Department of Breast Oncology, Cancer Institute Hospital, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
Breast Cancer 18:268-72. 2011..We examined the clinical behavior of these lesions in an attempt to determine appropriate management. We evaluated long-term outcome and clinical characteristics of malignant phyllodes tumors arising from fibroadenomas of the breast... - Clinicopathological significance of invasive micropapillary carcinoma component in invasive breast carcinomaYoshimi Ide
Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
Pathol Int 61:731-6. 2011..The presence of IMP components was a significant predictive factor for nodal metastasis, even if it is detected in only a small proportion of the tumor... - Apocrine metaplasia of breast cancer: clinicopathological features and predicting responseAkiko Ogiya
Department of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Koto ku, Tokyo, Japan
Breast Cancer 17:290-7. 2010..We thus considered that apocrine metaplasia (AM) might represent a predictive marker for breast cancer... - What causes discrepancies in HER2 testing for breast cancer? A Japanese ring study in conjunction with the global standardShinobu Umemura
Department of Pathology, Tokai University School of Medicine, Isehara, Japan
Am J Clin Pathol 130:883-91. 2008..By performing FISH retesting for these samples, consistency among multiple institutions could be archived. The quality of the staining procedures performed and the consistency of evaluations require regular assessment... - Breast cancer associated with mammary hamartomaMasaya Kai
Department of Breast Surgery, Cancer Institute Hospital, Koto ku, Tokyo, Japan
Breast Cancer 19:183-6. 2012..We describe a case of invasive ductal carcinoma arising in the mammary hamartoma during the follow-up period of a previously diagnosed hamartoma... - Histogenesis of metaplastic breast carcinoma and axillary nodal metastasesTomo Osako
Division of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake, Koto ku, Tokyo, Japan
Pathol Int 59:116-20. 2009..This suggested that the ductal component metastasized to the nodes and that epithelial-mesenchymal transition subsequently occurred within the nodes... 
Assessment of hormone receptor status in breast cancerRie Horii
Department of Pathology, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan
Pathol Int 57:784-90. 2007..When assessing hormone receptors of breast cancer in routine clinical settings, it is sufficient to determine the proportion of positive cells in the entire cancer area...- Histological features of breast cancer, highly sensitive to chemotherapyRie Horii
Department of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Koto ku, Tokyo, 135 8550, Japan
Breast Cancer 14:393-400. 2007..To establish tailor-made therapy for breast cancer, we investigated the possibility of predicting chemotherapy sensitive cases based on pre-therapeutic histological features... - Spontaneous " healing" of breast cancerRie Horii
Department of Breast Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 10 6, Ariake, Koto ku, Tokyo 135 8550, Japan
Breast Cancer 12:140-4. 2005..Healing is a phenomenon by which the intraductal component of breast cancer disappears and is replaced by fibrous tissue. Focally localized healing often prevents confirmation of the continuity of intraductal carcinoma... - Neoadjuvant chemotherapy followed by radical hysterectomy plus postoperative chemotherapy but no radiotherapy for Stage IB2-IIB cervical cancer--irinotecan and platinum chemotherapyMaki Matsumura
Department of Gynecology, Cancer Institute Hospital, Ariake 3 8 31, Koutou ku, Tokyo 135 8550, Japan
Gynecol Oncol 119:212-6. 2010..To evaluate the effectiveness of neoadjuvant chemotherapy (NAC) followed by radical hysterectomy plus postoperative chemotherapy but no radiotherapy for stage IB2-IIB cervical cancer... - Intraductal papilloma with bloody discharge from Montgomery's areolar tubercle examined by ductoscopy from the areolaTakehiko Sakai
Breast Pathology Section, Cancer Institute, Japanese Foundation for Cancer Research, 3 10 6, Ariake, Tokyo 135 8550, Japan
Breast Cancer 13:104-6. 2006..Although there are a few breast carcinomas that cause bloody discharge and eruption of areola, areolar preservation should be performed with the knowledge that disease may also involve the areola through the lactiferous ducts... - Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: Molecular whole-node analysis of all removed nodesTomo Osako
Division of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan Department of Pathology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3 8 31, Ariake, Koto ku, Tokyo 135 8550, Japan Electronic address
Eur J Cancer 49:1187-95. 2013..We aim to reveal the usefulness of the OSNA assay regarding the prediction of non-SN metastasis... - Detection of occult invasion in ductal carcinoma in situ of the breast with sentinel node metastasisTomo Osako
Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan
Cancer Sci 104:453-7. 2013..Patient follow-up is required to elucidate the prognostic impact of nodal metastasis and occult invasion... - Carcinoma in a solitary intraductal papilloma of the breastRin Yamaguchi
Department of Pathology, Cancer Institute Hospital, Tokyo, Japan
Pathol Int 59:185-7. 2009..An additional partial mastectomy was performed after the lumpectomy but no carcinoma foci were noted in the excised tissue. Possible occurrence of cancerous change in solitary intraductal papilloma of the breast was suspected... - Clinical and pathologic features of fibroadenoma of the mastopathic typeHajime Kuroda
Department of Pathology, Saitama Medical Center, Saitama Medical School, 1981 Tsujido, Kamoda, Kawagoe, Saitama, Japan
Surg Today 36:590-5. 2006..Thus, not only pathologists but also clinicians must be able to recognize this type of fibroadenoma, and cooperate closely to establish an accurate diagnosis... - Prognostic value of matrix Gla protein in breast cancerKeiko Yoshimura
Genome Center, Japanese Foundation for Cancer Research, Cancer Institute Hospital, Tokyo 135 8550, Japan
Mol Med Report 2:549-53. 2009..In breast cancer cases, the mRNA level of MGP may be a marker indicating poor prognosis; however, protein expression determined by immunohistostaining is not... - One-step nucleic acid amplification for intraoperative detection of lymph node metastasis in breast cancer patientsMasahiko Tsujimoto
Department of Pathology, Osaka Police Hospital, Japan
Clin Cancer Res 13:4807-16. 2007..The purpose of this study is to develop a more efficient method for intraoperative detection of lymph node metastasis... - Histopathological criteria for assessment of therapeutic response in breast cancer (2007 version)Masafumi Kurosumi
Department of Pathology, Saitama Cancer Center, Saitama, Japan
Breast Cancer 15:5-7. 2008 - Recommendations for 'adequate evaluation of hormone receptors' a report of the task force of the Japanese Breast Cancer SocietyShinobu Umemura
Department of Pathology, Tokai University School of Medicine, Isehara 259 1193, Japan
Oncol Rep 24:299-304. 2010..Herein, we summarize the evidence, on which the recommendations were made, and customize the recommendations suitable for the current status... - Proposal of a novel method for observing the breast by high-resolution ultrasound imaging: understanding the normal breast structure and its application in an observational method for detecting deviationsAyumi Izumori
The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3 8 31 Ariake, Koto ku, Tokyo, 135 8550, Japan
Breast Cancer 20:83-91. 2013..We elucidated the detailed histological architecture of the normal breast, information indispensable for diagnostic US of the breast... - [Histological features of breast cancer as predictive factors for chemotherapy]Rie Horii
Department of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research
Nippon Rinsho 65:160-4. 2007 - Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancerYoko Oishi
Department of Molecular Diagnosis, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
J Hum Genet 52:271-9. 2007..We also determined that immunohistostaining for the Stathmin1 gene product is a potential tool for predicting the outcome of breast cancer patients with supraclavicular lymph node metastasis... - Classification of ipsilateral breast tumor recurrence after breast-conserving therapy: new primary cancer allows a good prognosisSeiichiro Nishimura
Department of Breast Surgery, Cancer Institute Ariake Hospital, 3 10 6, Ariake, Koto ku, Tokyo 135 8550, Japan
Breast Cancer 12:112-7. 2005..To classify and assess ipsilateral breast tumor recurrences (IBTR) after breast-conserving therapy... - Evaluation of HER-2 status in breast carcinoma by fluorescence in situ hybridization and immunohistochemistryHiroyuki Ogura
Department of Breast Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 1-37-1, Kami-Ikebukuro, Toshima-ku, Tokyo 170-8455, Japan
Breast Cancer 10:234-40. 2003..CONCLUSIONS: Our results indicated that an IHC score of 3+ is equivalent to FISH-positivity for HER-2 diagnosis, while patients with an IHC score of 2+ should undergo FISH testing...