Takeshi Asano

Summary

Country: Japan

Publications

  1. doi request reprint Hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation in children: a nationwide survey in Japan
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inzai City, Chiba, Japan
    Pediatr Blood Cancer 59:110-4. 2012
  2. ncbi request reprint Urinary tract malformation and infection with hyperkalemia and decreased fractional excretion of potassium in an infant
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School Graduate School of Medicine, Chiba, Japan
    J Nippon Med Sch 73:289-91. 2006
  3. ncbi request reprint Neurocutaneous melanosis with acute disseminated encephalomyelitis
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba gun, Chiba Pref, 270 1894, Japan
    Eur J Pediatr 166:1065-6. 2007
  4. doi request reprint Enhanced expression of cytokines/chemokines in cerebrospinal fluids in mumps meningitis in children
    Takeshi Asano
    Departments of Pediatrics Emergency and Critical Care Medicine, Nippon Medical School, Chiba Hokusoh Hospital, Chiba, Japan
    Pediatr Int 53:143-6. 2011
  5. ncbi request reprint Usefulness of DNA analysis of tuberculosis with ruptured lymphadenitis in a bacille Calmette-Guérin-vaccinated infant
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba, Chiba, Japan
    Pediatr Int 49:392-4. 2007
  6. ncbi request reprint Transient thrombocytopenia with large platelets in Kawasaki disease
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba Pref, Japan
    Pediatr Hematol Oncol 24:551-4. 2007
  7. ncbi request reprint Acute pancreatitis complicating typhoid fever in a 4-year-old girl
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Kamakari, Chiba, Japan
    Pediatr Int 49:1004-6. 2007
  8. doi request reprint Indomethacin overcomes doxorubicin resistance by decreasing intracellular content of glutathione and its conjugates with decreasing expression of gamma-glutamylcysteine synthetase via promoter activity in doxorubicin-resistant leukemia cells
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba gun, Chiba, Japan
    Cancer Chemother Pharmacol 64:715-21. 2009
  9. ncbi request reprint Fungal thoracic Spondylodiskitis in an immunocompetent 14-year-old girl
    Takeshi Asano
    Department of Pediatrics, Graduate School of Medicine, Nippon Medical School Chiba Hokusoh Hospital, Inba gun, Chiba, Japan
    J Nippon Med Sch 76:265-7. 2009
  10. ncbi request reprint Concomitant severe normocytic and normochromic anemia in poststreptococcal acute glomerulonephritis
    Takeshi Asano
    Department of Pediatrics, Graduate School of Medicine, Nippon Medical School, Inba gun, Chiba, Japan
    J Nippon Med Sch 76:272-4. 2009

Detail Information

Publications31

  1. doi request reprint Hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation in children: a nationwide survey in Japan
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inzai City, Chiba, Japan
    Pediatr Blood Cancer 59:110-4. 2012
    ..Although HLH can be also observed after hematopoietic stem cell transplantation (HSCT), the incidence and clinical features of HLH after HSCT remain obscure...
  2. ncbi request reprint Urinary tract malformation and infection with hyperkalemia and decreased fractional excretion of potassium in an infant
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School Graduate School of Medicine, Chiba, Japan
    J Nippon Med Sch 73:289-91. 2006
    ....
  3. ncbi request reprint Neurocutaneous melanosis with acute disseminated encephalomyelitis
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba gun, Chiba Pref, 270 1894, Japan
    Eur J Pediatr 166:1065-6. 2007
  4. doi request reprint Enhanced expression of cytokines/chemokines in cerebrospinal fluids in mumps meningitis in children
    Takeshi Asano
    Departments of Pediatrics Emergency and Critical Care Medicine, Nippon Medical School, Chiba Hokusoh Hospital, Chiba, Japan
    Pediatr Int 53:143-6. 2011
    ..We compared data obtained from patients with mumps meningitis and patients with aseptic meningitis caused by other viruses in order to identify mumps meningitis-specific cytokine/chemokine alterations in cerebrospinal fluid (CSF)...
  5. ncbi request reprint Usefulness of DNA analysis of tuberculosis with ruptured lymphadenitis in a bacille Calmette-Guérin-vaccinated infant
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba, Chiba, Japan
    Pediatr Int 49:392-4. 2007
  6. ncbi request reprint Transient thrombocytopenia with large platelets in Kawasaki disease
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba Pref, Japan
    Pediatr Hematol Oncol 24:551-4. 2007
    ..6%). The authors believe that it is important for clinicians to be aware that thrombocytopenia may occur during the course of KD and that this may be a more active condition when compared with thrombocytosis...
  7. ncbi request reprint Acute pancreatitis complicating typhoid fever in a 4-year-old girl
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Kamakari, Chiba, Japan
    Pediatr Int 49:1004-6. 2007
    ..Pancreatitis represents an extremely rare complication of typhoid fever. Herein we report the case of a 4-year-old Bangladeshi girl with acute pancreatitis caused by Salmonella typhi...
  8. doi request reprint Indomethacin overcomes doxorubicin resistance by decreasing intracellular content of glutathione and its conjugates with decreasing expression of gamma-glutamylcysteine synthetase via promoter activity in doxorubicin-resistant leukemia cells
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba gun, Chiba, Japan
    Cancer Chemother Pharmacol 64:715-21. 2009
    ....
  9. ncbi request reprint Fungal thoracic Spondylodiskitis in an immunocompetent 14-year-old girl
    Takeshi Asano
    Department of Pediatrics, Graduate School of Medicine, Nippon Medical School Chiba Hokusoh Hospital, Inba gun, Chiba, Japan
    J Nippon Med Sch 76:265-7. 2009
    ....
  10. ncbi request reprint Concomitant severe normocytic and normochromic anemia in poststreptococcal acute glomerulonephritis
    Takeshi Asano
    Department of Pediatrics, Graduate School of Medicine, Nippon Medical School, Inba gun, Chiba, Japan
    J Nippon Med Sch 76:272-4. 2009
    ..We speculate that these factors combined to cause an unusual case of severe anemia in PSAGN...
  11. doi request reprint High prevalence of antibodies against Bartonella henselae with cervical lymphadenopathy in children
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba, Japan
    Pediatr Int 52:533-5. 2010
    ....
  12. doi request reprint IL-17 is elevated in cerebrospinal fluids in bacterial meningitis in children
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba Pref 270 1694, Japan
    Cytokine 51:101-6. 2010
    ..We found that, IL-17 was significantly elevated in CSF with bacterial meningitis. We believe that IL-17 plays a key role in neutrophil infiltration into CSF and neuronal protection in bacterial meningitis...
  13. ncbi request reprint A 13-year-old girl with a preoperatively diagnosed solid cystic tumor of the pancreas
    Takeshi Asano
    Department of Pediatrics, Chiba Hokusoh Hospital, Nippon Medical School, Inbu gun, Chiba, Japan
    J Nippon Med Sch 73:231-4. 2006
    ..Light microscopy of the tumor confirmed small neoplastic cells. Pathological diagnosis was solid pseudopapillary tumor (solid cystic tumor) of the pancreas. Surgery was successful, and the postoperative course was uneventful...
  14. ncbi request reprint Transient thrombocytopenia after incompatible red blood transfusion in an infant girl with autoimmune hemolytic anemia
    Takeshi Asano
    Department of Pediatrics, Chiba Hokusoh Hospital, Nippon Medical School, Inba gun, Chiba, Japan
    J Nippon Med Sch 73:93-6. 2006
    ..The platelet count and hemoglobin levels gradually improved over 8 weeks with corticosteroid therapy. We suspect that the thrombocytopenia in our patient was transfusion-induced...
  15. doi request reprint High mobility group box 1 in cerebrospinal fluid from several neurological diseases at early time points
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba, Japan
    Int J Neurosci 121:480-4. 2011
    ..In conclusion, HMGB1 is a poor disease marker for acute encephalopathy...
  16. ncbi request reprint Acute pancreatitis with Kawasaki disease: analysis of cases with elevated serum amylase levels
    Takeshi Asano
    Department of Paediatrics, Nippon Medical School, Chiba Hokusoh Hospital, 1715 Kamakari, Inba mura, 270 1694 Inba gun, Chiba Pref, Japan
    Eur J Pediatr 164:180-1. 2005
  17. pmc Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation
    T Asano
    Department of Pediatrics, Nippon Medical School, Tokyo, Japan
    Br J Cancer 92:1486-92. 2005
    ....
  18. ncbi request reprint Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome in a 14-year-old boy: an immunohistochemical study of infiltrating lymphocytes in acneous skin regions
    Takeshi Asano
    Department of Paediatrics, Nippon Medical School, Chiba Hokusoh Hospital, 1715 Kamakari, Inba gun, Inba mura, 2701694 Chiba, Japan
    Eur J Pediatr 164:466-8. 2005
  19. ncbi request reprint Adenovirus-mediated human topoisomerase IIalpha gene transfer increases the sensitivity of etoposide-resistant human and mouse breast cancer cells
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Japan
    Acta Oncol 44:240-7. 2005
    ..We concluded that a recombinant adenovirus containing the human Topoisomerase IIalpha gene might be a powerful tool for overcoming drug resistance in breast cancer cells, but not in leukemia cells...
  20. doi request reprint IL-8 in cerebrospinal fluid from children with acute encephalopathy is higher than in that from children with febrile seizure
    T Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Chiba Pre, Japan
    Scand J Immunol 71:447-51. 2010
    ..IL-8 in CSF was also higher than serum IL-8, suggesting that increased IL-8 was generated from glia cells or astrocytes, not by leakage from serum. Increased IL-8 in CSF in encephalopathy may protect against severe brain damage...
  21. pmc Identification of a novel biomarker candidate, a 4.8-kDa peptide fragment from a neurosecretory protein VGF precursor, by proteomic analysis of cerebrospinal fluid from children with acute encephalopathy using SELDI-TOF-MS
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inzai City, Chiba, Japan
    BMC Neurol 11:101. 2011
    ..The purpose of this study was to identify a novel marker candidate protein differentially expressed in the cerebrospinal fluid (CSF) of children with encephalopathy using proteomic analysis...
  22. ncbi request reprint Clinical aspects of infant leukemia--experiences of a single institution of Japan: high level of serum immunoglobulin M in infant leukemia
    Miho Maeda
    Department of Pediatrics, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 72:355-63. 2005
    ..Infant leukemia patients in our institution had some special features. CNS involvement at diagnosis was seen in only 1 patient and serum IgM levels were higher than those in children whose leukemia was diagnosed at 1 to 10 years of age...
  23. ncbi request reprint Indomethacin overcomes doxorubicin resistance with inhibiting multi-drug resistance protein 1 (MRP1)
    Seita Matsunaga
    Department of Pediatrics, Nippon Medical School, Chiba Hokusoh Hospital, Inba mura, Inba gun, Japan
    Cancer Chemother Pharmacol 58:348-53. 2006
    ..These data strongly suggest that the cyclooxygenase inhibitor, indomethacin, increased the cytotoxicity of doxorubicin with decreasing expression of MRP1 through inhibition of MRP1 promoter activity...
  24. ncbi request reprint Successful immunosuppressive therapy for a child with Myelodysplastic syndrome
    Mizue Orimoto
    Department of Pediatrics, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, Japan
    Med Pediatr Oncol 40:334-5. 2003
  25. ncbi request reprint Brain white matter changes during treatment of a child for acute lymphoblastic leukemia
    Miho Maeda
    Department of Pediatrics, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo 113 8603, Japan
    J Nippon Med Sch 72:252-3. 2005
    ..Methotrexate has been considered to be responsible for ischemic damage to oligodendroglial cells, resulting in demyelination. The changes are occasionally prolonged without persistent neurologic symptoms...
  26. ncbi request reprint Delayed-type hypersensitivity in response to L-asparaginase in a case of acute lymphoblastic leukemia
    Hidehiko Narazaki
    Department of Pediatrics, Chiba Hokusoh Hospital, Nippon Medical School, Inzai, Chiba, Japan
    J Nippon Med Sch 79:489-93. 2012
    ..No asparaginases other than E. coli L-Asp have been approved for use in Japan. Other asparaginases, such as polyethylene glycol L-Asp and Erwinia L-Asp should be quickly approved for use as alternative chemotherapy reagents in Japan...
  27. ncbi request reprint Solid and cystic tumor of the pancreas in a 12-year-old boy
    Takeshi Asano
    Departments of Pediatrics, Nippon Medical School, Tokyo, Japan
    Pediatr Int 45:339-41. 2003
  28. ncbi request reprint Possible synergic effect of angiotensin-I converting enzyme gene insertion/deletion polymorphism and angiotensin-II type-1 receptor 1166A/C gene polymorphism on ischemic heart disease in patients with Kawasaki disease
    Ryuji Fukazawa
    Department of Pediatrics, Nippon Medical School, 113 8603 Tokyo, Japan
    Pediatr Res 56:597-601. 2004
    ..These results suggested that the renin-angiotensin system is associated with the formation of severe coronary artery stenosis and myocardial ischemia...
  29. ncbi request reprint [Acute suppurative thyroiditis in 7 year-old girl with piriform sinus fistula]
    Takeshi Asano
    Department of Pediatrics, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 69:593-6. 2002
    ..We diagnosed her as acute suppurative thyroiditis and treated her with intravenous antibiotics infusion and incisional drainage. After the treatment, the clinical course was uneventful. Pharyngograph revealed left piriform sinus fistula...
  30. pmc Distinct mechanisms of ferritin delivery to lysosomes in iron-depleted and iron-replete cells
    Takeshi Asano
    Department of Biophysics and Biochemistry, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Mol Cell Biol 31:2040-52. 2011
    ....
  31. ncbi request reprint Zanamivir is an effective treatment for influenza in children undergoing therapy for acute lymphoblastic leukemia
    Miho Maeda
    Department of Pediatrics, Nippon Medical School, Tokyo, Japan
    Scand J Infect Dis 34:632-3. 2002
    ..We conclude that inhaled zanamivir seems to be an effective treatment for influenza infection in immunocompromised patients...