Research Topics
Species | Shigetaka YoshidaSummaryAffiliation: Asahikawa Medical College Country: Japan Publications
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Detail Information
Publications
Implications of protease M/neurosin in myelination during experimental demyelination and remyelinationYoshio Bando
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, Asahikawa, Hokkaido 078 8510, Japan
Neurosci Lett 405:175-80. 2006..Our data emphasize that the maintenance of myelination is an important function of protease M/neurosin in OLGs, suggesting its relation to the oligodendroglial response to myelin disorders...
Differential changes in axonal conduction following CNS demyelination in two mouse modelsYoshio Bando
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, Asahikawa, Hokkaido 078 8510, Japan
Eur J Neurosci 28:1731-42. 2008....
Klk8, a multifunctional protease in the brain and skin: analysis of knockout miceShigetaka Yoshida
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, Hokkaido, Japan
Biol Chem 391:375-80. 2010..Klk8 might be involved in desquamation through the degradation of adhesive molecules that connect layers of the epidermis. Klk8 might thus be involved in tissue development and rearrangement...
Involvement of neuropsin in the pathogenesis of experimental autoimmune encephalomyelitisRyuji Terayama
Department of Anatomy, Asahikawa Medical College, Asahikawa, Japan
Glia 52:108-18. 2005..These observations suggest that neuropsin is involved in the pathogenesis of EAE mediated by demyelination and oligodendroglial death...
Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreinsMari Kishibe
Departments of Structural Anatomy and Neuroscience and Dermatology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
J Biol Chem 282:5834-41. 2007..We propose that in psoriatic lesion, KLK8 modulates hyperproliferation and prevents excessive hyperkeratosis by shedding the corneocytes...
Regeneration of the abdominal postganglionic sympathetic systemMasahiro Yamada
Department of Anatomy 1, Asahikawa Medical College, Japan
Neurosci Res 54:261-8. 2006..Therefore, postganglionic sympathetic nerves in the abdomen are able to regenerate and reinnervation occurs even after the removal of sympathetic ganglia...
Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosisRyuji Terayama
Department of Anatomy, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
Neurosci Lett 382:82-7. 2005..These observations suggest that the differential expression of protease M/neurosin in mature oligodendrocytes and their progenitors is involved in the pathogenesis of MS and EAE...
Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cordRyuji Terayama
Department of Anatomy, Asahikawa Medical College, Asahikawa 078 8510, Japan
Glia 48:91-101. 2004..These findings suggest that each subpopulation of oligodendrocytes based on the expression of neuropsin and protease M/neurosin has different roles in the response of the spinal cord to injury as well as in normal homeostasis...
Epidermal lamellar granules transport different cargoes as distinct aggregatesAkemi Ishida-Yamamoto
Department of Dermatology, Asahikawa Medical College, Asahikawa, Japan
J Invest Dermatol 122:1137-44. 2004..This study provides strong evidence for the sequential synthesis and independent trafficking of various LG cargoes, including for the first time CatD and KLK8, from TGN...
Three-dimensional ultra-structures of myelin and the axons in the spinal cord: Application of SEM with the osmium maceration method to the central nervous system in two mouse modelsTaichi Nomura
Department of Functional Anatomy and Neuroscience, Asahikawa Medical University, Asahikawa 078 8510, Japan
Neurosci Res 75:190-7. 2013..This technique will be a powerful tool for identifying the mechanisms underlying the pathogenesis in demyelination...
[Kallikrein-family serine protease in the central nervous system]Shigetaka Yoshida
Department of Anatomy 1, Asahikawa Medical College, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Hokkaido 078-8510, Japan
Kaibogaku Zasshi 78:77-82. 2003..These proteases in balance with inhibitors are implicated in the modulation of the extracellular environment...
