Taiji Nagaoka

Summary

Affiliation: Asahikawa Medical College
Country: Japan

Publications

  1. pmc Relationship between retinal blood flow and renal function in patients with type 2 diabetes and chronic kidney disease
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Diabetes Care 36:957-61. 2013
  2. doi request reprint Impaired retinal circulation in patients with type 2 diabetes mellitus: retinal laser Doppler velocimetry study
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 51:6729-34. 2010
  3. doi request reprint Effect of aging on retinal circulation in normotensive healthy subjects
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8502, Japan
    Exp Eye Res 89:887-91. 2009
  4. doi request reprint C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production
    Taiji Nagaoka
    Department of Ophthalmology, Scott and White Eye Institute, Temple, TX 76504, USA
    Invest Ophthalmol Vis Sci 49:2053-60. 2008
  5. ncbi request reprint Retinal circulatory changes associated with interferon-induced retinopathy in patients with hepatitis C
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 48:368-75. 2007
  6. ncbi request reprint [Physiological mechanism for the regulation of ocular circulation]
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Japan
    Nihon Ganka Gakkai Zasshi 110:872-8. 2006
  7. ncbi request reprint Effect of systemic administration of simvastatin on retinal circulation
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
    Arch Ophthalmol 124:665-70. 2006
  8. ncbi request reprint Noninvasive evaluation of wall shear stress on retinal microcirculation in humans
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 47:1113-9. 2006
  9. ncbi request reprint Relationship between the parameters of retinal circulation measured by laser Doppler velocimetry and a marker of early systemic atherosclerosis
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Invest Ophthalmol Vis Sci 46:720-5. 2005
  10. pmc Effect of haemodialysis on retinal circulation in patients with end stage renal disease
    T Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa, 078 8510, Japan
    Br J Ophthalmol 88:1026-9. 2004

Collaborators

Detail Information

Publications66

  1. pmc Relationship between retinal blood flow and renal function in patients with type 2 diabetes and chronic kidney disease
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Diabetes Care 36:957-61. 2013
    ..To study the relationship between retinal microcirculation and renal function in patients with type 2 diabetes...
  2. doi request reprint Impaired retinal circulation in patients with type 2 diabetes mellitus: retinal laser Doppler velocimetry study
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 51:6729-34. 2010
    ..To evaluate the differences in retinal circulation in eyes of patients with type 2 diabetes with no or early-stage diabetic retinopathy compared with control eyes...
  3. doi request reprint Effect of aging on retinal circulation in normotensive healthy subjects
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8502, Japan
    Exp Eye Res 89:887-91. 2009
    ..The UT is the only parameter that increased significantly in subjects with prehypertension compared with those without prehypertension, suggesting that the UT may indicate the effects of prehypertension on the retinal arterioles...
  4. doi request reprint C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation of retinal arterioles via enhanced superoxide production
    Taiji Nagaoka
    Department of Ophthalmology, Scott and White Eye Institute, Temple, TX 76504, USA
    Invest Ophthalmol Vis Sci 49:2053-60. 2008
    ....
  5. ncbi request reprint Retinal circulatory changes associated with interferon-induced retinopathy in patients with hepatitis C
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 48:368-75. 2007
    ..To evaluate the effect of interferon (IFN) therapy on retinal microcirculation...
  6. ncbi request reprint [Physiological mechanism for the regulation of ocular circulation]
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Japan
    Nihon Ganka Gakkai Zasshi 110:872-8. 2006
    ..Ocular warming increased RBF in the retinal artery and vein but decreased CBF in the foveal region. The CBF in the foveal region may contribute to maintaining a constant retinal temperature in response to ocular warming...
  7. ncbi request reprint Effect of systemic administration of simvastatin on retinal circulation
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
    Arch Ophthalmol 124:665-70. 2006
    ..To investigate the effect of systemic administration of simvastatin on the retinal circulation...
  8. ncbi request reprint Noninvasive evaluation of wall shear stress on retinal microcirculation in humans
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 47:1113-9. 2006
    ..To evaluate wall shear stress (WSS) on retinal microcirculation noninvasively...
  9. ncbi request reprint Relationship between the parameters of retinal circulation measured by laser Doppler velocimetry and a marker of early systemic atherosclerosis
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Invest Ophthalmol Vis Sci 46:720-5. 2005
    ..To examine the relation between intima-media thickness (IMT) in the common carotid artery, which is generally recognized as a marker of early atherosclerosis, and retinal circulatory parameters...
  10. pmc Effect of haemodialysis on retinal circulation in patients with end stage renal disease
    T Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa, 078 8510, Japan
    Br J Ophthalmol 88:1026-9. 2004
    ..To investigate the effect of haemodialysis on retinal circulation in patients with end stage renal disease (ESRD)...
  11. ncbi request reprint Retinal artery response to acute systemic blood pressure increase during cold pressor test in humans
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 43:1941-5. 2002
    ..The purpose of this study was to investigate the response of the retinal arteriole to an acute increase in systemic blood pressure (BP)...
  12. ncbi request reprint The effect of nitric oxide on retinal blood flow during hypoxia in cats
    Taiji Nagaoka
    Departments of Ophthalmology and Physiology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 43:3037-44. 2002
    ..To investigate how nitric oxide (NO) contributes to the regulation of retinal circulation during rest and hypoxia in cats...
  13. ncbi request reprint The effect of ocular warming on ocular circulation in healthy humans
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Arch Ophthalmol 122:1477-81. 2004
    ..To examine the effect of ocular warming on retinal blood flow (RBF) and subfoveal choroidal blood flow (CBF) in humans...
  14. pmc Alteration of choroidal circulation in the foveal region in patients with type 2 diabetes
    T Nagaoka
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa, 078 8510, Japan
    Br J Ophthalmol 88:1060-3. 2004
    ..To investigate changes in choroidal blood flow (CBF) in the foveal region in patients with type 2 diabetes...
  15. doi request reprint Role of nitric oxide in regulation of retinal blood flow in response to hyperoxia in cats
    Naohiro Izumi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    Invest Ophthalmol Vis Sci 49:4595-603. 2008
    ..To investigate whether nitric oxide (NO) regulates retinal circulation during and after induction of hyperoxia in cats...
  16. doi request reprint Retinal arteriolar responses to acute severe elevation in systemic blood pressure in cats: role of endothelium-derived factors
    Seigo Nakabayashi
    Department of Ophthalmology, Asahikawa Medical University, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
    Exp Eye Res 103:63-70. 2012
    ..It appears that the retinal endothelium, by releasing vasoactive substances, contributes to RBF regulation during acute severe elevation of systemic blood pressure...
  17. doi request reprint Homocysteine inhibition of endothelium-dependent nitric oxide-mediated dilation of porcine retinal arterioles via enhanced superoxide production
    Tsuneaki Omae
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 54:2288-95. 2013
    ....
  18. doi request reprint Acute hyperglycemia-induced endothelial dysfunction in retinal arterioles in cats
    Kenji Sogawa
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    Invest Ophthalmol Vis Sci 51:2648-55. 2010
    ..To investigate the effects of acute hyperglycemia on retinal microcirculation and endothelial function in cats and removal of superoxide to prevent retinal endothelial dysfunction from hyperglycemia...
  19. doi request reprint Idiopathic full-thickness macular holes and the vitreomacular interface: a high-resolution spectral-domain optical coherence tomography study
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
    Am J Ophthalmol 154:881-892.e2. 2012
    ..To analyze the vitreomacular interface in idiopathic full-thickness macular holes (MHs) using spectral-domain optical coherence tomography...
  20. doi request reprint Impaired systemic vascular endothelial function in patients with branch retinal vein occlusion
    Ichiro Tanano
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Curr Eye Res 38:114-8. 2013
    ..To evaluate systemic endothelial function in patients with branch retinal vein occlusion (BRVO)...
  21. doi request reprint Association between diabetic retinopathy and flow-mediated vasodilation in type 2 DM
    Kenji Sogawa
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    Curr Eye Res 37:446-51. 2012
    ..Brachial artery flow-mediated vasodilation (FMD) is a marker of endothelial function associated with production of endogenous nitric oxide. Using FMD, we investigated the relationship between macrovascular function and DR...
  22. doi request reprint Short-term effects of topical tafluprost on retinal blood flow in cats
    Naohiro Izumi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    J Ocul Pharmacol Ther 24:521-6. 2008
    ..The aim of this study was to determine the short-term effects of topical tafluprost, a novel prostaglandin F(2) derivative, on feline retinal circulation...
  23. doi request reprint Adiponectin-induced dilation of isolated porcine retinal arterioles via production of nitric oxide from endothelial cells
    Tsuneaki Omae
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 54:4586-94. 2013
    ..However, the action of adiponectin in the retinal microcirculation is unknown. We examined the direct effect and underlying mechanism of the vasomotor action of adiponectin in porcine retinal arterioles...
  24. ncbi request reprint Resveratrol, a component of red wine, elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels
    Taiji Nagaoka
    Department of Ophthalmology, Scott and White Eye Institute, College of Medicine, Texas A and M Health Science Center, Temple, TX 76504, USA
    Invest Ophthalmol Vis Sci 48:4232-9. 2007
    ..In this study, the direct effect and the underlying mechanism of the vasomotor action of resveratrol were examined in retinal arterioles...
  25. ncbi request reprint Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways
    Taiji Nagaoka
    Department of Ophthalmology, Scott and White Eye Institute, Temple, Texas 76504, USA
    Invest Ophthalmol Vis Sci 48:825-32. 2007
    ..In the current study, the direct effect and the underlying mechanism of the vasomotor action of simvastatin in retinal arterioles was studied...
  26. ncbi request reprint Role of nitric oxide in regulation of retinal blood flow during hypercapnia in cats
    Eiichi Sato
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 44:4947-53. 2003
    ..To investigate whether nitric oxide (NO) contributes to the regulation of retinal circulation during hypercapnia in cats...
  27. ncbi request reprint Dilation of porcine retinal arterioles to cilostazol: roles of eNOS phosphorylation via cAMP/protein kinase A and AMP-activated protein kinase and potassium channels
    Ichiro Tanano
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 54:1443-9. 2013
    ..We examined the effects of cilostazol on the retinal microvascular diameter to determine its dependence on the endothelium and/or smooth muscle to reveal the signaling mechanisms involved in this vasomotor activity...
  28. doi request reprint Fenofibrate, an anti-dyslipidemia drug, elicits the dilation of isolated porcine retinal arterioles: role of nitric oxide and AMP-activated protein kinase
    Tsuneaki Omae
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 53:2880-6. 2012
    ..In the current study, we examined the effect of the vasomotor action of fenofibrate on porcine retinal arterioles...
  29. doi request reprint Macular hole formation in fellow eyes with a perifoveal posterior vitreous detachment of patients with a unilateral macular hole
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, 2 1 1 1 Midorigaoka Higashi, Hokkaido, Japan
    Am J Ophthalmol 151:981-989.e4. 2011
    ....
  30. ncbi request reprint Role of Ca2+ -dependent and Ca2+ -sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro
    Takayuki Kamiya
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Exp Eye Res 121:94-101. 2014
    ....
  31. ncbi request reprint Autoregulation of retinal blood flow in response to decreased ocular perfusion pressure in cats: comparison of the effects of increased intraocular pressure and systemic hypotension
    Tomofumi Tani
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 55:360-7. 2014
    ..To investigate the regulatory mechanisms responsible for autoregulation of retinal blood flow (RBF) during periods of decreased ocular perfusion pressure (OPP)...
  32. doi request reprint Relationship between choroidal thickness and choroidal circulation in healthy young subjects
    Kenji Sogawa
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Am J Ophthalmol 153:1129-32.e1. 2012
    ..To investigate the relationship between the choroidal thickness and choroidal blood flow in healthy young subjects...
  33. pmc Functional and molecular characterization of the endothelin system in retinal arterioles
    Travis W Hein
    Department of Ophthalmology, Scott and White Eye Institute, Temple, Texas 76504, USA
    Invest Ophthalmol Vis Sci 50:3329-36. 2009
    ..The authors examined the roles of ET(A) and ET(B) receptors and of endothelin-converting enzyme (ECE)-1 in ET-1-induced vasomotor responses of single retinal arterioles...
  34. doi request reprint Effects of topical carteolol on retinal arterial blood flow in primary open-angle glaucoma patients
    Motofumi Kawai
    Department of Ophthalmology, Asahikawa Medical University, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
    Jpn J Ophthalmol 56:458-63. 2012
    ..Our aim was to evaluate the effects of topical carteolol on retinal arterial blood flow (RBF) in patients with primary open-angle glaucoma...
  35. doi request reprint Correlation between plasma pentosidine concentrations and retinal hemodynamics in patients with type 2 diabetes
    Eiichi Sato
    Department of Ophthalmology, Asahikawa Medical University, Japan
    Am J Ophthalmol 153:903-909.e1. 2012
    ..To investigate whether plasma pentosidine, a well-defined advanced glycation end product, is associated with retinal hemodynamic abnormalities in patients with type 2 diabetes...
  36. doi request reprint Pioglitazone, a peroxisome proliferator-activated receptor-γ agonist, induces dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels
    Tsuneaki Omae
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 52:6749-56. 2011
    ....
  37. ncbi request reprint Pulsatile ocular blood flow: changes associated with scleral buckling procedures
    Harumasa Yokota
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Jpn J Ophthalmol 49:162-5. 2005
    ..To determine the changes in the pulse amplitude (PA) and the pulsatile ocular blood flow (POBF) after scleral buckling (SB)...
  38. doi request reprint Spontaneous outer retinal closure of stage 1B macular hole without vitreofoveal separation
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1, Midorigaoka Higashi, Asahikawa, Hokkaido, 078 8510, Japan
    Int Ophthalmol 30:731-4. 2010
    ..This case demonstrates that spontaneous closure in the outer retina may develop in some cases of stage 1B macular holes without vitreofoveal separation...
  39. ncbi request reprint [The change of retinal arteriolar circulation in a case of branch retinal artery occlusion]
    Tsuneaki Omae
    Department of Ophthalmology, Asahikawa Medical College, Japan
    Nihon Ganka Gakkai Zasshi 113:800-7. 2009
    ....
  40. ncbi request reprint Role of prorenin in the pathogenesis of retinal neovascularization
    Harumasa Yokota
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Hokkaido Igaku Zasshi 83:159-65. 2008
    ..To determine the role of prorenin in the pathogenesis of retinal neovascularization, we evaluated the inhibitory effect of the handle region peptide (HRP) on retinal neovascularization...
  41. doi request reprint Influence of macular microcirculation and retinal thickness on visual acuity in patients with branch retinal vein occlusion and macular edema
    Hidetaka Noma
    Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women s Medical University, Chiba, Japan
    Jpn J Ophthalmol 54:430-4. 2010
    ..To investigate perifoveal capillary blood flow velocity and retinal thickness at the central fovea in patients with branch retinal vein occlusion (BRVO) and macular edema and to assess their relation with visual acuity and visual prognosis...
  42. doi request reprint Stage 1-A macular hole: a prospective spectral-domain optical coherence tomography study
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Retina 31:127-47. 2011
    ....
  43. ncbi request reprint Relationship between retinal fractal dimensions and retinal circulation in patients with type 2 diabetes mellitus
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Curr Eye Res 38:1148-52. 2013
    ..To investigate the relationship between retinal fractal dimensions (Dfs) and retinal circulation, which is impaired in early-stage diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM)...
  44. ncbi request reprint Relation between plasma nitric oxide levels and diabetic retinopathy
    Naohiro Izumi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Jpn J Ophthalmol 50:465-8. 2006
    ..The purpose of this study was to determine the relationship between plasma NO levels and DR...
  45. doi request reprint Higher levels of prorenin predict development of diabetic retinopathy in patients with type 2 diabetes
    Harumasa Yokota
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    J Renin Angiotensin Aldosterone Syst 12:290-4. 2011
    ..However, there was no difference in the development of DR between high and low groups in females (p = 0.58). Serum prorenin levels in males with type 2 diabetes could be a new prognostic indicator of the development of DR...
  46. ncbi request reprint Vitreomacular interface in patients with familial exudative vitreoretinopathy
    Akito Shimouchi
    Department of Ophthalmology, Asahikawa Medical University, 2 1 1 1, Midorigaoka Higashi, 078 8510, Asahikawa, Hokkaido, Japan
    Int Ophthalmol 33:711-5. 2013
    ....
  47. doi request reprint Low shear stress up-regulation of proinflammatory gene expression in human retinal microvascular endothelial cells
    Akihiro Ishibazawa
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan Department of Ocular Tissue Engineering, Asahikawa Medical University, Asahikawa, Japan Electronic address
    Exp Eye Res 116:308-11. 2013
    ....
  48. ncbi request reprint [Long-term clinical course and changes in the choroidal circulation in the foveal region in a case of juvenile retinitis pigmentosa with bilateral cystoid macular edema]
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical College, Hokkaido, Japan
    Nihon Ganka Gakkai Zasshi 113:656-63. 2009
    ....
  49. ncbi request reprint [Evaluation of retinal circulation in patients with diabetic retinopathy]
    Taiji Nagaoka
    Department of Ophthalmology, Asahikawa Medical College
    Nihon Rinsho 63:220-5. 2005
  50. ncbi request reprint Reproducibility and clinical application of a newly developed stabilized retinal laser Doppler instrument
    Akitoshi Yoshida
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Am J Ophthalmol 135:356-61. 2003
    ..To describe a newly developed stabilized retinal laser Doppler instrument, to report the reproducibility of retinal blood flow measurements, and to present examples of its clinical application...
  51. ncbi request reprint Inhibitory effect of bucillamine on the increased leukocyte entrapment in the retinal microcirculation of diabetic rats
    Fumihiko Mori
    Department of Ophthalmology, Hakodate Goryokaku Hospital, Hakodate, and Department of Ophthalmology, Asahikawa Medical College, Japan
    Jpn J Ophthalmol 50:377-9. 2006
    ..To evaluate quantitatively the effects of bucillamine on the entrapment of leukocytes in the retinal microcirculation of diabetic rats...
  52. ncbi request reprint Prorenin levels in retinopathy of prematurity
    Harumasa Yokota
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Am J Ophthalmol 143:531-3. 2007
    ..To evaluate serum prorenin levels in preterm infants with or without retinopathy of prematurity (ROP)...
  53. ncbi request reprint [Pathogenesis of macular edema associated with branch retinal vein occlusion and strategy for treatment]
    Hidetaka Noma
    Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women s Medical University, 477 96 Owada Shinden, Yachiyo shi, Chiba ken 276 8524, Japan
    Nihon Ganka Gakkai Zasshi 114:577-91. 2010
    ..To manage macular edema associated with BRVO, it is important to control cytokine production with a combination of treatments...
  54. doi request reprint Effects of shear stress on the gene expressions of endothelial nitric oxide synthase, endothelin-1, and thrombomodulin in human retinal microvascular endothelial cells
    Akihiro Ishibazawa
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan
    Invest Ophthalmol Vis Sci 52:8496-504. 2011
    ..Physiological shear stress is higher in the retinal microcirculatory network than in other organs. The effects of laminar shear stress on gene expression in human retinal microvascular endothelial cells (HRMECs) was investigated...
  55. doi request reprint Foveal anatomic changes in a progressing stage 1 macular hole documented by spectral-domain optical coherence tomography
    Atsushi Takahashi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
    Ophthalmology 117:806-10. 2010
    ..To report the case of a stage 1 macular hole and the sequential intrafoveal changes with spectral-domain optical coherence tomography (SD-OCT)...
  56. doi request reprint Effect of panretinal photocoagulation on choroidal circulation in the foveal region in patients with severe diabetic retinopathy
    A Takahashi
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Br J Ophthalmol 92:1369-73. 2008
    ..To study alterations in choroidal blood flow (CBF) in the foveal region after panretinal photocoagulation (PRP) in patients with severe proliferative diabetic retinopathy...
  57. ncbi request reprint Effect of timolol and UF-021 (a prostaglandin-related compound) on pulsatile ocular blood flow in normal volunteers
    N Kitaya
    Department of Ophthalmology, Asahikawa Medical College, Japan
    Ophthalmic Res 29:139-44. 1997
    ..Our results suggest that in normal subjects timolol decreases POBF in both the treated and the untreated eyes, whereas UF-021 has no action on either IOP or POBF...
  58. pmc Choroidal blood flow in the foveal region in eyes with rhegmatogenous retinal detachment and scleral buckling procedures
    R Sugawara
    Department of Ophthalmology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
    Br J Ophthalmol 90:1363-5. 2006
    ..To investigate changes in choroidal blood flow (ChBF) in the foveal region of the human eye with rhegmatogenous retinal detachment induced by scleral buckling...
  59. pmc Serum prorenin levels and diabetic retinopathy in type 2 diabetes: new method to measure serum level of prorenin using antibody activating direct kinetic assay
    H Yokota
    Department of Ophthalmology, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa, 078 8510 Japan
    Br J Ophthalmol 89:871-3. 2005
    ..To investigate the serum levels of prorenin and its correlation with the severity of diabetic retinopathy (DR)...
  60. pmc Features of abnormal choroidal circulation in central serous chorioretinopathy
    N Kitaya
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Br J Ophthalmol 87:709-12. 2003
    ..To evaluate abnormalities in the choroidal circulation in cases of central serous chorioretinopathy (CSC)...
  61. doi request reprint Central corneal thickness measurements with Fourier-domain optical coherence tomography versus ultrasonic pachymetry and rotating Scheimpflug camera
    Akihiro Ishibazawa
    Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
    Cornea 30:615-9. 2011
    ..To compare the accuracy and repeatability of Fourier-domain optical coherence tomography (FD-OCT) with ultrasonic pachymetry (USP) and a rotating Scheimpflug camera for measuring the central corneal thickness (CCT)...
  62. doi request reprint Macular microcirculation and macular oedema in branch retinal vein occlusion
    H Noma
    Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women s Medical University, Yachiyo, Chiba 276 8524, Japan
    Br J Ophthalmol 93:630-3. 2009
    ..The relationship between the blood-flow velocity in the perifoveal capillaries and macular oedema was investigated in patients with branch retinal vein occlusion (BRVO)...
  63. ncbi request reprint Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats
    R Sugawara
    Department of Ophthalmology, Asahikawa Medical College, Midorogaoka Higashi 2 1 Asahikawa 078 8510, Japan
    Curr Eye Res 29:11-6. 2004
    ..We evaluated the effectiveness of the peroxynitrite decomposition catalyst, FP15, and the PARP inhibitor, PJ34, in the treatment of leukocyte entrapment in the retinal microcirculation of diabetic rats...
  64. pmc Inhibitory effect of losartan, an AT1 angiotensin II receptor antagonist, on increased leucocyte entrapment in retinal microcirculation of diabetic rats
    F Mori
    Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
    Br J Ophthalmol 86:1172-4. 2002
    ..The effectiveness of losartan for the treatment of leucocyte entrapment in the retinal microcirculation of diabetic rats was evaluated quantitatively...
  65. ncbi request reprint Pulsatile ocular blood flow is unaffected in type 2 diabetes mellitus
    Fumihiko Mori
    Jpn J Ophthalmol 47:621-2. 2003
  66. ncbi request reprint Dysfunction of active transport of blood-retinal barrier in patients with clinically significant macular edema in type 2 diabetes
    Fumihiko Mori
    Diabetes Care 25:1248-9. 2002