M Eto

Summary

Affiliation: Asahikawa Medical College
Country: Japan

Publications

  1. ncbi request reprint Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    CNS Neurol Disord Drug Targets 6:411-23. 2007
  2. ncbi request reprint Oxidative RNA damage and neurodegeneration
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Higashi 2 1 1 1, Midorigaoka, Asahikawa 078 8510, Japan
    Curr Med Chem 14:2968-75. 2007
  3. ncbi request reprint Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream
    Akihiko Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Sci Aging Knowledge Environ 2006:pe10. 2006
  4. ncbi request reprint Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
    Akihiko Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Neurobiol Dis 17:108-13. 2004
  5. ncbi request reprint Apolipoprotein E polymorphism and susceptibility to early- and late-onset sporadic Alzheimer's disease in Hokkaido, the northern part of Japan
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Japan
    Neurosci Lett 206:17-20. 1996
  6. ncbi request reprint Detection of the association between a deletion polymorphism in the gene encoding angiotensin I-converting enzyme and advanced diabetic retinopathy
    A Matsumoto
    Second Department of Internal Medicine, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa, Japan
    Diabetes Res Clin Pract 50:195-202. 2000
  7. ncbi request reprint The effect of dilazep on urinary protein excretion in spontaneous diabetic Chinese hamster
    A Morikawa
    Second Department of Internal Medicine, Asahikawa Medical College, Japan
    Nephron 65:125-32. 1993
  8. ncbi request reprint Estrogen prevents oxidative stress-induced endothelial cell apoptosis in rats
    N Sudoh
    Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Circulation 103:724-9. 2001
  9. ncbi request reprint Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia
    F Cosentino
    Cardiovascular Centre, University Hospital, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Heart 94:487-92. 2008

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    CNS Neurol Disord Drug Targets 6:411-23. 2007
    ..An enhancement of the pro-longevity signaling (e.g. caloric restriction) may be a promising approach as anti-oxidative strategy against age-associated neurodegenerative diseases...
  2. ncbi request reprint Oxidative RNA damage and neurodegeneration
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Higashi 2 1 1 1, Midorigaoka, Asahikawa 078 8510, Japan
    Curr Med Chem 14:2968-75. 2007
    ....
  3. ncbi request reprint Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream
    Akihiko Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Sci Aging Knowledge Environ 2006:pe10. 2006
    ..Moreover, if this concept holds true for pathology in other neurodegenerative diseases, we may need to restructure our thinking and undergo a paradigm shift before substantial progress can be made in therapeutic intervention...
  4. ncbi request reprint Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
    Akihiko Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa 078 8510, Japan
    Neurobiol Dis 17:108-13. 2004
    ..These results suggest that oxidative stress is an early event involved in the pathological cascade of FAD...
  5. ncbi request reprint Apolipoprotein E polymorphism and susceptibility to early- and late-onset sporadic Alzheimer's disease in Hokkaido, the northern part of Japan
    A Nunomura
    Department of Psychiatry and Neurology, Asahikawa Medical College, Japan
    Neurosci Lett 206:17-20. 1996
    ..Our results indicate that the ApoE-epsilon 4 allele is associated with susceptibility to Japanese sporadic AD developing after 50 years of age and homozygosity for the epsilon 4 allele shifts the onset to earlier age...
  6. ncbi request reprint Detection of the association between a deletion polymorphism in the gene encoding angiotensin I-converting enzyme and advanced diabetic retinopathy
    A Matsumoto
    Second Department of Internal Medicine, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa, Japan
    Diabetes Res Clin Pract 50:195-202. 2000
    ..89, P=0.027), respectively. These results indicate a significant relationship between the presence of the D allele polymorphism in the ACE gene and ADR in Japanese subjects with type 2 diabetes and no overt nephropathy...
  7. ncbi request reprint The effect of dilazep on urinary protein excretion in spontaneous diabetic Chinese hamster
    A Morikawa
    Second Department of Internal Medicine, Asahikawa Medical College, Japan
    Nephron 65:125-32. 1993
    ..It was concluded that dilazep administration suppressed urinary protein excretion in diabetic Chinese hamster possibly through the preservation of charge barrier of the glomerulus...
  8. ncbi request reprint Estrogen prevents oxidative stress-induced endothelial cell apoptosis in rats
    N Sudoh
    Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Circulation 103:724-9. 2001
    ..Progesterone did not influence the effects of estradiol on EC apoptosis. CONCLUSIONS: These results provide new insight into the cardioprotective action of estrogen as well as a paradigm of the response-to-injury hypothesis...
  9. ncbi request reprint Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia
    F Cosentino
    Cardiovascular Centre, University Hospital, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Heart 94:487-92. 2008
    ..Both mechanisms contribute to atherosclerotic vascular disease. Although acute supplementation of BH(4) improves endothelial dysfunction, the effect of chronic BH(4) in humans is unknown...