Research Topics
Genomes and Genes | Y BandoSummaryAffiliation: Asahikawa Medical College Country: Japan Publications
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Detail Information
Publications
150-kDa oxygen-regulated protein attenuates myocardial ischemia-reperfusion injury in rat heartAlexey N Aleshin
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
J Mol Cell Cardiol 38:517-25. 2005..Our results indicated cytoprotective roles for ORP150 in rat heart and suggested a therapeutic role for the protein both in preventing cardiomyocyte death and in preserving contractile function after ischemic damage...- Phosphorylated PKR contributes the induction of GRP94 under ER stressMototsugu Ito
Graduate School of Pharmaceutical Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 13 0033, Japan
Biochem Biophys Res Commun 360:615-20. 2007..These results suggest that a novel mechanism other than ERSE-dependent mRNA transcription is required for the induction of GRP94 and phosphorylation of PKR contributes to the induction of GRP94 under ER stress... 
The functional role of stress proteins in ER stress mediated cell deathYoshio Bando
Department of Functional Anatomy and Neuroscience, Asahikawa Medical University, Asahikawa, 078 8510, Japan
Anat Sci Int 87:14-23. 2012..These findings suggest that hypoxia and oxidative stress target the ER and secretory pathway, resulting in ER stress, and that these proteins exert cytoprotective effects in various diseases associated with ER stress...- Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's diseaseYoshio Bando
Department of Anatomy, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
Neurochem Int 46:11-8. 2005..These results suggest that a close association exists between PKR and extrastriatal degeneration in PD and HD pathology... - ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell deathYoshio Bando
Department of Anatomy I, Asahikawa Medical College, Asahikawa, Hokkaido, Japan
FASEB J 18:1401-3. 2004..These data are consistent with the possibility that ORP150 exerts cytoprotective effects in renal tubular epithelia subjected to I/R injury and suggest a key role for ER stress in the renal tubular response to acute renal failure... - GRP94 reduces cell death in SH-SY5Y cells perturbated calcium homeostasisY Bando
Department of Anatomy and Neuroscience, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
Apoptosis 9:501-8. 2004..These results indicated that suppression of GRP94 is associated with accelerated cell death. Moreover, expression of GRP94 suppressed A23187-induced cell death and stabilized calcium homeostasis... - Implications of protease M/neurosin in myelination during experimental demyelination and remyelinationYoshio Bando
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, Asahikawa, Hokkaido 078 8510, Japan
Neurosci Lett 405:175-80. 2006..Our data emphasize that the maintenance of myelination is an important function of protease M/neurosin in OLGs, suggesting its relation to the oligodendroglial response to myelin disorders... - Differential changes in axonal conduction following CNS demyelination in two mouse modelsYoshio Bando
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, Asahikawa, Hokkaido 078 8510, Japan
Eur J Neurosci 28:1731-42. 2008.... - GRP94 (94 kDa glucose-regulated protein) suppresses ischemic neuronal cell death against ischemia/reperfusion injuryYoshio Bando
Department of Anatomy and Neuroscience, Osaka University Graduate School of Medicine, Osaka, Japan
Eur J Neurosci 18:829-40. 2003..These results confirmed that GRP94 could suppress ischemic injury to neurons, suggesting that gene transfer of GRP94 into the brain may have therapeutic potential in the treatment of cerebrovascular disease... - RA410/Sly1 suppresses MPP+ and 6-hydroxydopamine-induced cell death in SH-SY5Y cellsYoshio Bando
Department of Anatomy and Neuroscience, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
Neurobiol Dis 18:143-51. 2005..These results suggest that RA410/Sly1 plays an important cytoprotective role in MPP+ and 6-OHDA-induced cellular perturbation... - Neuropsin promotes oligodendrocyte death, demyelination and axonal degeneration after spinal cord injuryR Terayama
Department of Functional Anatomy and Neuroscience, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
Neuroscience 148:175-87. 2007..These observations suggest that neuropsin is involved in the secondary phase of the pathogenesis of SCI mediated by demyelination, oligodendrocyte death, and axonal degeneration... - Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brainM Aoki
Department of Traumatology, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, 565 0871, Osaka, Japan
Brain Res Mol Brain Res 95:117-28. 2001..These results suggest that reduction in GRP78 expression contributes to cell damage in the ischemic brain and that hypothermia-mediated restoration of GRP78 expression is one mechanism that enhances neuronal survival... - 150-kDa oxygen-regulated protein (ORP150) functions as a novel molecular chaperone in MDCK cellsY Bando
Department of Anatomy and Neuroscience, Osaka University Graduate School of Medicine, Suita City, Japan
Am J Physiol Cell Physiol 278:C1172-82. 2000..These data indicate that ORP150 may function as a unique molecular chaperone in renal epithelial cells by facilitating protein transport/maturation in an environment where less ATP is accessible... 
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell deathJunichi Hitomi
Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
J Cell Biol 165:347-56. 2004..Thus, caspase-4 can function as an ER stress-specific caspase in humans, and may be involved in pathogenesis of Alzheimer's disease...- Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosisRyuji Terayama
Department of Anatomy, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
Neurosci Lett 382:82-7. 2005..These observations suggest that the differential expression of protease M/neurosin in mature oligodendrocytes and their progenitors is involved in the pathogenesis of MS and EAE... - Differential expression of neuropsin and protease M/neurosin in oligodendrocytes after injury to the spinal cordRyuji Terayama
Department of Anatomy, Asahikawa Medical College, Asahikawa 078 8510, Japan
Glia 48:91-101. 2004..These findings suggest that each subpopulation of oligodendrocytes based on the expression of neuropsin and protease M/neurosin has different roles in the response of the spinal cord to injury as well as in normal homeostasis... - Involvement of neuropsin in the pathogenesis of experimental autoimmune encephalomyelitisRyuji Terayama
Department of Anatomy, Asahikawa Medical College, Asahikawa, Japan
Glia 52:108-18. 2005..These observations suggest that neuropsin is involved in the pathogenesis of EAE mediated by demyelination and oligodendroglial death... - Novel function of PS2V: change in conformation of tau proteinsAtsuko Nishikawa
Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan
Biochem Biophys Res Commun 318:435-8. 2004..In this manuscript, we make the first report of PS2V alterations in the conformation of the tau protein (unknown form of tau) in the human neuroblastoma cell line... - Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreinsMari Kishibe
Departments of Structural Anatomy and Neuroscience and Dermatology, Asahikawa Medical College, Midorigaoka Higashi 2 1 1 1, Asahikawa 078 8510, Japan
J Biol Chem 282:5834-41. 2007..We propose that in psoriatic lesion, KLK8 modulates hyperproliferation and prevents excessive hyperkeratosis by shedding the corneocytes... - Novel interaction between HMGA1a and StIP1 in murine terminally differentiated retinaHiroaki Okuda
Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
Mol Cell Neurosci 33:81-7. 2006.... - Regeneration of the abdominal postganglionic sympathetic systemMasahiro Yamada
Department of Anatomy 1, Asahikawa Medical College, Japan
Neurosci Res 54:261-8. 2006..Therefore, postganglionic sympathetic nerves in the abdomen are able to regenerate and reinnervation occurs even after the removal of sympathetic ganglia... - Possible involvement of the expression and phosphorylation of N-Myc in the induction of HMGA1a by hypoxia in the human neuroblastoma cell lineTakeshi Yanagita
Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka, Japan
Neurosci Lett 374:47-52. 2005..Such signal consolidation processes could play a role in neuronal survival after hypoxia in neurons... - HMGA1a: sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNATakayuki Manabe
Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
Genes Cells 12:1179-91. 2007..These results provide insights into the molecular basis for PS2V-associated neurodegenerative diseases that are initiated by specific RNA binding of HMGA1a... 
An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's diseaseReiko Onuki
Gene Function Research Center, National Institute of Advanced Industrial Science and Technology, Higashi, Tsukuba Science City, Japan
EMBO J 23:959-68. 2004..We also detected the accumulation of phosphorylated PKR in the nuclei of autopsied brain tissues in Alzheimer's disease. Thus, PKR might play a role in ER stress-induced apoptosis and in Alzheimer's disease...- Immobilization of proteins on boron nitride nanotubesChunyi Zhi
Advanced Materials Laboratory, National Institute for Materials Science NIMS, Namiki 1 1, Tsukuba, Ibaraki 305 0044, Japan
J Am Chem Soc 127:17144-5. 2005..For the most effective immobilization, noncovalently functionalized BNNTs should be used. The effect of immobilization was studied using high-resolution transmission electron microscopy and energy dispersion spectroscopy... - CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitisBing Zhu
Center for Neurologic Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Immunol 179:5228-37. 2007..Further understanding of suppressive monocytes in autoimmune disease models may have important clinical implications for human autoimmune diseases... - Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitisMei Ling Chen
Center for Neurologic Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
J Immunol 180:7327-37. 2008..Our work helps elucidate the ambiguity concerning the role of TGFbeta in CD4(+)CD25(+) Treg-mediated suppression and indicates that LAP is an authentic marker able to identify a TGFbeta-expressing CD4(+)CD25(+) Treg subset...