Toshihiko Shoji

Summary

Affiliation: Asahi Breweries
Country: Japan

Publications

  1. ncbi request reprint Apple procyanidin oligomers absorption in rats after oral administration: analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
    J Agric Food Chem 54:884-92. 2006
  2. ncbi request reprint Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption
    Hiroshi Sugiyama
    Fundamental Research Laboratory, Asahi Breweries Limited, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
    J Agric Food Chem 55:4604-9. 2007
  3. ncbi request reprint Isolation and structural elucidation of some procyanidins from apple by low-temperature nuclear magnetic resonance
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Agric Food Chem 51:3806-13. 2003
  4. ncbi request reprint Apple (Malus pumila) procyanidins fractionated according to the degree of polymerization using normal-phase chromatography and characterized by HPLC-ESI/MS and MALDI-TOF/MS
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Chromatogr A 1102:206-13. 2006
  5. ncbi request reprint Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cells
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Agric Food Chem 53:6105-11. 2005
  6. ncbi request reprint Characterization and structures of anthocyanin pigments generated in rosé cider during vinification
    Toshihiko Shoji
    Institute for Production Research and Development, Nikka Whisky Distilling Co, Ltd, 967 Matsuyama, Masuo, Kashiwa, Chiba 277 0033, Japan
    Phytochemistry 59:183-9. 2002
  7. doi request reprint Cloning of a novel O-methyltransferase from Camellia sinensis and synthesis of o-methylated EGCG and evaluation of their bioactivity
    Masanobu Kirita
    Research Laboratories for Fundamental Technology of Food, Asahi Breweries Limited, Moriya shi, Ibaraki, Japan
    J Agric Food Chem 58:7196-201. 2010
  8. ncbi request reprint Dietary unripe apple polyphenol inhibits the development of food allergies in murine models
    Hiroshi Akiyama
    National Institute of Health Sciences, 1 18 1, Kamiyoga, Setagaya ku Tokyo 158 8501, Japan
    FEBS Lett 579:4485-91. 2005
  9. ncbi request reprint Separation of proanthocyanidins by degree of polymerization by means of size-exclusion chromatography and related techniques
    Akio Yanagida
    Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1, Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Biochem Biophys Methods 56:311-22. 2003
  10. ncbi request reprint Chiral recognition of apple procyanidins by complexation with oxotitanium phthalocyanine
    Atsuya Muranaka
    Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980 8578, Japan
    Org Lett 8:2447-50. 2006

Collaborators

  • Hiroshi Akiyama
  • Akio Yanagida
  • Yoko Akazome
  • Mari Maeda-Yamamoto
  • Daiki Honma
  • M Kobori
  • Tomomasa Kanda
  • Atsuya Muranaka
  • Yasuyuki Ohtake
  • Masanobu Kirita
  • Tomisato Miura
  • Hiroshi Sugiyama
  • Masanobu Uchiyama
  • Toyokazu Yokota
  • Yoshihisa Tanaka
  • Motoyuki Tagashira
  • Shinya Usui
  • Manabu Sami
  • Mitsuru Chiba
  • Hiroyuki Nozaka
  • Toshiya Nakamura
  • Kosuke Kasai
  • Tatsusuke Sato
  • Masaaki Yasue
  • Atsuko Yamaguchi
  • Nina Moriichi
  • Saeko Masumoto
  • Nagao Kobayashi
  • Kengo Yoshida

Detail Information

Publications12

  1. ncbi request reprint Apple procyanidin oligomers absorption in rats after oral administration: analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
    J Agric Food Chem 54:884-92. 2006
    ..These results suggest that ACTs are absorbed and directly involved in physiological functions in the rats...
  2. ncbi request reprint Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption
    Hiroshi Sugiyama
    Fundamental Research Laboratory, Asahi Breweries Limited, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
    J Agric Food Chem 55:4604-9. 2007
    ..These results suggested that the oligomeric procyanidins contained in AP inhibited triglyceride absorption by inhibiting pancreatic lipase activity in mice and humans...
  3. ncbi request reprint Isolation and structural elucidation of some procyanidins from apple by low-temperature nuclear magnetic resonance
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Agric Food Chem 51:3806-13. 2003
    ..Compounds 6-11 were detected for the first time as apple constituents...
  4. ncbi request reprint Apple (Malus pumila) procyanidins fractionated according to the degree of polymerization using normal-phase chromatography and characterized by HPLC-ESI/MS and MALDI-TOF/MS
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Chromatogr A 1102:206-13. 2006
    ..This method will be useful for the evaluation of the physiological functions of proanthocyanidins and for the elucidation of their individual structures...
  5. ncbi request reprint Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cells
    Toshihiko Shoji
    Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
    J Agric Food Chem 53:6105-11. 2005
    ..No correlation between the degree of procyanidin polymerization and tyrosinase inhibitory activity was observed. Nevertheless, these observations suggest that procyanidins are effective inhibitors of tyrosinase...
  6. ncbi request reprint Characterization and structures of anthocyanin pigments generated in rosé cider during vinification
    Toshihiko Shoji
    Institute for Production Research and Development, Nikka Whisky Distilling Co, Ltd, 967 Matsuyama, Masuo, Kashiwa, Chiba 277 0033, Japan
    Phytochemistry 59:183-9. 2002
    ..These two pigments were found to consist of cyanidin-3-galactoside and (-)-epicatechin linked by a CH(3)-CH bridge at the 8-position. They were diastereomers that differed in the configuration of the asymmetric methine carbon...
  7. doi request reprint Cloning of a novel O-methyltransferase from Camellia sinensis and synthesis of o-methylated EGCG and evaluation of their bioactivity
    Masanobu Kirita
    Research Laboratories for Fundamental Technology of Food, Asahi Breweries Limited, Moriya shi, Ibaraki, Japan
    J Agric Food Chem 58:7196-201. 2010
    ..In contrast, the inhibition of histamine release was potentiated by an increase in the number of methyl groups in EGCG, especially in the galloyl moiety...
  8. ncbi request reprint Dietary unripe apple polyphenol inhibits the development of food allergies in murine models
    Hiroshi Akiyama
    National Institute of Health Sciences, 1 18 1, Kamiyoga, Setagaya ku Tokyo 158 8501, Japan
    FEBS Lett 579:4485-91. 2005
    ..This suggests that the ACT intake may prevent the development of food allergies and this effect could be correlated with the rise in the percentage of TCR(gamma)delta-T cells among the IEL...
  9. ncbi request reprint Separation of proanthocyanidins by degree of polymerization by means of size-exclusion chromatography and related techniques
    Akio Yanagida
    Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1, Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Biochem Biophys Methods 56:311-22. 2003
    ....
  10. ncbi request reprint Chiral recognition of apple procyanidins by complexation with oxotitanium phthalocyanine
    Atsuya Muranaka
    Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980 8578, Japan
    Org Lett 8:2447-50. 2006
    ..700 nm). The helicity of the oligomeric procyanidins is proposed to be left-handed on the basis of the CD analyses. [structure: see text]..
  11. ncbi request reprint Characterization of polymerized polyphenols by size-exclusion HPLC
    Akio Yanagida
    Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Biosci Biotechnol Biochem 66:1972-5. 2002
    ..This rapid analytical method may also be useful for the profiling of molecular mass distribution of polyphenolic constituents in many kinds of food materials...
  12. ncbi request reprint Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3
    Tomisato Miura
    Department of Pathologic analysis, Hirosaki University Graduate School of Health Sciences, 66 1, Hon cho, Hirosaki, Aomori 036 8564, Japan
    Carcinogenesis 29:585-93. 2008
    ..Our results indicate that the oral administration of apple procyanidins inhibits the proliferation of tumor cells by inducing apoptosis through the intrinsic mitochondrial pathway...