Research Topics
| Toshihiko ShojiSummaryAffiliation: Asahi Breweries Country: Japan Publications
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Detail Information
Publications
Apple procyanidin oligomers absorption in rats after oral administration: analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometryToshihiko Shoji
Fundamental Research Laboratory, Asahi Breweries, Ltd, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
J Agric Food Chem 54:884-92. 2006..These results suggest that ACTs are absorbed and directly involved in physiological functions in the rats...- Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorptionHiroshi Sugiyama
Fundamental Research Laboratory, Asahi Breweries Limited, I 21, Midori 1 chome, Moriya shi, Ibaraki 302 0106, Japan
J Agric Food Chem 55:4604-9. 2007..These results suggested that the oligomeric procyanidins contained in AP inhibited triglyceride absorption by inhibiting pancreatic lipase activity in mice and humans... - Isolation and structural elucidation of some procyanidins from apple by low-temperature nuclear magnetic resonanceToshihiko Shoji
Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
J Agric Food Chem 51:3806-13. 2003..Compounds 6-11 were detected for the first time as apple constituents... - Apple (Malus pumila) procyanidins fractionated according to the degree of polymerization using normal-phase chromatography and characterized by HPLC-ESI/MS and MALDI-TOF/MSToshihiko Shoji
Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
J Chromatogr A 1102:206-13. 2006..This method will be useful for the evaluation of the physiological functions of proanthocyanidins and for the elucidation of their individual structures... - Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cellsToshihiko Shoji
Fundamental Research Laboratory, Asahi Breweries, Ltd, 1 21 Midori 1 Chome, Moriya, Ibaraki 302 0106, Japan
J Agric Food Chem 53:6105-11. 2005..No correlation between the degree of procyanidin polymerization and tyrosinase inhibitory activity was observed. Nevertheless, these observations suggest that procyanidins are effective inhibitors of tyrosinase... - Characterization and structures of anthocyanin pigments generated in rosé cider during vinificationToshihiko Shoji
Institute for Production Research and Development, Nikka Whisky Distilling Co, Ltd, 967 Matsuyama, Masuo, Kashiwa, Chiba 277 0033, Japan
Phytochemistry 59:183-9. 2002..These two pigments were found to consist of cyanidin-3-galactoside and (-)-epicatechin linked by a CH(3)-CH bridge at the 8-position. They were diastereomers that differed in the configuration of the asymmetric methine carbon... 
Cloning of a novel O-methyltransferase from Camellia sinensis and synthesis of o-methylated EGCG and evaluation of their bioactivityMasanobu Kirita
Research Laboratories for Fundamental Technology of Food, Asahi Breweries Limited, Moriya shi, Ibaraki, Japan
J Agric Food Chem 58:7196-201. 2010..In contrast, the inhibition of histamine release was potentiated by an increase in the number of methyl groups in EGCG, especially in the galloyl moiety...- Dietary unripe apple polyphenol inhibits the development of food allergies in murine modelsHiroshi Akiyama
National Institute of Health Sciences, 1 18 1, Kamiyoga, Setagaya ku Tokyo 158 8501, Japan
FEBS Lett 579:4485-91. 2005..This suggests that the ACT intake may prevent the development of food allergies and this effect could be correlated with the rise in the percentage of TCR(gamma)delta-T cells among the IEL... - Separation of proanthocyanidins by degree of polymerization by means of size-exclusion chromatography and related techniquesAkio Yanagida
Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1, Horinouchi, Hachioji, Tokyo 192 0392, Japan
J Biochem Biophys Methods 56:311-22. 2003.... - Chiral recognition of apple procyanidins by complexation with oxotitanium phthalocyanineAtsuya Muranaka
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan
Org Lett 8:2447-50. 2006..700 nm). The helicity of the oligomeric procyanidins is proposed to be left-handed on the basis of the CD analyses. [structure: see text].. - Characterization of polymerized polyphenols by size-exclusion HPLCAkio Yanagida
Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
Biosci Biotechnol Biochem 66:1972-5. 2002..This rapid analytical method may also be useful for the profiling of molecular mass distribution of polyphenolic constituents in many kinds of food materials... - Apple procyanidins induce tumor cell apoptosis through mitochondrial pathway activation of caspase-3Tomisato Miura
Department of Pathologic analysis, Hirosaki University Graduate School of Health Sciences, 66 1, Hon cho, Hirosaki, Aomori 036 8564, Japan
Carcinogenesis 29:585-93. 2008..Our results indicate that the oral administration of apple procyanidins inhibits the proliferation of tumor cells by inducing apoptosis through the intrinsic mitochondrial pathway...