Kin ya Kubo

Summary

Affiliation: Asahi University School of Dentistry
Country: Japan

Publications

  1. ncbi request reprint Molarless-induced changes of spines in hippocampal region of SAMP8 mice
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Brain Res 1057:191-5. 2005
  2. ncbi request reprint The bite-raised condition enhances the aging process in the dorsal and ventral hippocampus
    Kin ya Kubo
    Departments of Oral Anatomy, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 85:43-8. 2008
  3. doi request reprint The bite-raised condition in aged SAMP8 mice induces dendritic spine changes in the hippocampal region
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 441:141-4. 2008
  4. ncbi request reprint Denture-handling ability of elderly persons with dementia: examination of time spent inserting and removing dentures
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, Mizuho, Gifu, Japan
    Spec Care Dentist 27:149-53. 2007
  5. ncbi request reprint The distribution of proliferating cells during odontogenesis in the incisor teeth of Plecoglossus altivelis
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 1 Mozumi, Mizuho, Gifu 501 0296, Japan
    Okajimas Folia Anat Jpn 84:67-70. 2007
  6. ncbi request reprint Occlusal disharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 mice
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 414:188-91. 2007
  7. ncbi request reprint The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus
    Yukiko Ichihashi
    Department of Pediatric Dentistry, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 84:137-42. 2008
  8. ncbi request reprint Duration-dependent effects of the bite-raised condition on hippocampal function in SAMP8 mice
    Yoko Arakawa
    Department of Pediatric Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 84:115-9. 2007
  9. ncbi request reprint Occlusal disharmony attenuates glucocorticoid negative feedback in aged SAMP8 mice
    Yukiko Ichihashi
    Department of Pediatric Dentistry, Asahi University School of Dentistry, Mizuho, Japan
    Neurosci Lett 427:71-6. 2007
  10. doi request reprint Occlusal disharmony leads to learning deficits associated with decreased cellular proliferation in the hippocampal dentate gyrus of SAMP8 mice
    Daisuke Mori
    Department of Prosthodontics, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 534:228-32. 2013

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Molarless-induced changes of spines in hippocampal region of SAMP8 mice
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Brain Res 1057:191-5. 2005
    ..The results suggest the involvement of the molarless condition in an attenuation of input activities in the hippocampal synapses...
  2. ncbi request reprint The bite-raised condition enhances the aging process in the dorsal and ventral hippocampus
    Kin ya Kubo
    Departments of Oral Anatomy, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 85:43-8. 2008
    ..These data suggest that in aged SAMP8 mice, the bite-raised condition enhanced aging processes in both the dorsal and ventral hippocampus...
  3. doi request reprint The bite-raised condition in aged SAMP8 mice induces dendritic spine changes in the hippocampal region
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 441:141-4. 2008
    ..The results suggest that the bite-raised condition exacerbates the age-related spatial learning impairment, and that this may be due to the degeneration of hippocampal dendritic spines...
  4. ncbi request reprint Denture-handling ability of elderly persons with dementia: examination of time spent inserting and removing dentures
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, Mizuho, Gifu, Japan
    Spec Care Dentist 27:149-53. 2007
    ..The results indicate that elderly people with mild to moderate dementia are able to insert and remove their dentures without help...
  5. ncbi request reprint The distribution of proliferating cells during odontogenesis in the incisor teeth of Plecoglossus altivelis
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 1 Mozumi, Mizuho, Gifu 501 0296, Japan
    Okajimas Folia Anat Jpn 84:67-70. 2007
    ..These findings suggest that ameloblasts and odontoblasts actively divide around the region currently being formed, suggesting that enameloid and dentin are made in cooperation by ameloblasts and odontoblasts...
  6. ncbi request reprint Occlusal disharmony induces spatial memory impairment and hippocampal neuron degeneration via stress in SAMP8 mice
    Kin ya Kubo
    Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 414:188-91. 2007
    ..The findings suggest that the bite-raised condition in aged SAMP8 mice induces hippocampal neuron loss, thereby leading to senile memory deficits...
  7. ncbi request reprint The bite-raised condition in aged SAMP8 mice reduces the expression of glucocorticoid receptors in the dorsal and ventral hippocampus
    Yukiko Ichihashi
    Department of Pediatric Dentistry, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 84:137-42. 2008
    ..These findings suggest that in aged SAMP8 mice, the bite-raised condition decreases the number of GR-immunoreactive cells in both the dorsal and ventral hippocampus...
  8. ncbi request reprint Duration-dependent effects of the bite-raised condition on hippocampal function in SAMP8 mice
    Yoko Arakawa
    Department of Pediatric Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 84:115-9. 2007
    ..Thus, behavioral and morphologic deficits induced by the bite-raised condition in aged SAMP8 mice are influenced by the duration of the occlusal disharmony...
  9. ncbi request reprint Occlusal disharmony attenuates glucocorticoid negative feedback in aged SAMP8 mice
    Yukiko Ichihashi
    Department of Pediatric Dentistry, Asahi University School of Dentistry, Mizuho, Japan
    Neurosci Lett 427:71-6. 2007
    ..These findings suggest that the bite-raised condition in aged SAMP8 mice decreases GR and GRmRNA, which impairs the hypothalamic-pituitary-adrenal feedback inhibition, thereby leading to memory deficits...
  10. doi request reprint Occlusal disharmony leads to learning deficits associated with decreased cellular proliferation in the hippocampal dentate gyrus of SAMP8 mice
    Daisuke Mori
    Department of Prosthodontics, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 534:228-32. 2013
    ..These findings suggest that occlusal disharmony induced by raising the bite impaired cell proliferation in the hippocampal DG, leading to learning deficits...
  11. ncbi request reprint Malocclusion induces chronic stress
    Mitsuo Iinuma
    Department of Pediatric Dentistry, Division of Oral Structure, Function and Development, Mizuho, Gifu 501 0296, Japan
    Okajimas Folia Anat Jpn 85:35-42. 2008
    ..These datas suggest that the bite-raised condition may enhance the aging process in hippocampus, thereby leading to impairment of spatial memory by stress...
  12. ncbi request reprint Relationship between light and dark period activity cycles and oral condition in senescence-accelerated mice
    Mitsuo Iinuma
    Department of Pediatric Dentistry, Asahi University School of Dentistry, 1851 1 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Okajimas Folia Anat Jpn 88:29-36. 2011
    ..Significant correlations were noted among total activity, degree of senescence, and percent dark period activity in each experimental group. Functional masticatory insufficiency promoted dementia and behavioral abnormalities in SAMP1...
  13. doi request reprint Effect of bite-raised condition on the hippocampal cholinergic system of aged SAMP8 mice
    Tasuku Katayama
    Department of Prosthodontics, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 520:77-81. 2012
    ..These findings suggest that the bite-raised condition in aged SAMP8 mice enhances the age-related decline in the septohippocampal cholinergic system, leading to impaired learning...
  14. ncbi request reprint Chewing ameliorates chronic mild stress-induced bone loss in senescence-accelerated mouse (SAMP8), a murine model of senile osteoporosis
    Manabu Furuzawa
    Department of Prosthodontics, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu, 501 0296, Japan
    Exp Gerontol 55:12-8. 2014
    ..These findings indicate that chewing can ameliorate chronic stress-induced bone loss in SAMP8 mice. Thus, chewing may represent a useful method preventing and/or treating chronic stress-related osteoporosis. ..
  15. doi request reprint Learning deficits and suppression of the cell proliferation in the hippocampal dentate gyrus of offspring are attenuated by maternal chewing during prenatal stress
    Mika Onishi
    Department of Pediatric Dentistry, Asahi University School of Dentistry, 1851 Hozumi, Mizuho, Gifu 501 0296, Japan
    Neurosci Lett 560:77-80. 2014
    ..These findings suggest that maternal chewing during prenatal stress is an effective stress-coping method for the dam to prevent learning deficits and suppression of cell proliferation in offspring. ..
  16. doi request reprint Segmental variations in trabecular bone density and microstructure of the spine in senescence-accelerated mouse (SAMP6): a murine model for senile osteoporosis
    Huayue Chen
    Department of Anatomy, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu, 501 1194, Japan
    Exp Gerontol 47:317-22. 2012
    ..These findings highlight the relevance of SAMP6 for studies of vertebral fragility associated with senile osteoporosis...
  17. ncbi request reprint Gender-related changes in three-dimensional microstructure of trabecular bone at the human proximal tibia with aging
    Huayue Chen
    Department of Anatomy, Gifu University Graduate School of Medicine, Gifu, Japan
    Histol Histopathol 26:563-70. 2011
    ..These findings illustrate potential mechanisms underlying osteoporotic proximal tibial fracture...
  18. ncbi request reprint Double inferior vena cava with interiliac vein: a case report and literature review
    Huayue Chen
    Department of Anatomy, Gifu University Graduate School of Medicine, 1 1 Yanagido, Gifu, 501 1194, Japan
    Okajimas Folia Anat Jpn 88:147-51. 2012
    ..Thirteen left IVC displayed symmetrical-to-normal connection with the bilateral common iliac veins. Awareness of these venous variations is necessary to reduce surgical risk and to determine strategy in interventional radiology...