Affiliation: Akita University School of Medicine
Zhou M, Tanaka O, Sekiguchi M, He H, Yasuoka Y, Itoh H, et al
. ATP-sensitive K+-channel subunits on the mitochondria and endoplasmic reticulum of rat cardiomyocytes. J Histochem Cytochem. 2005;53:1491-500 pubmed
..The data obtained in this study will be useful for analyzing the composition of K(ATP) channels of cardiomyocytes and help to understanding the cardioprotective role of K(ATP) channels during heart ischemia...
Zhou M, He H, Suzuki R, Liu K, Tanaka O, Sekiguchi M, et al
. Localization of sulfonylurea receptor subunits, SUR2A and SUR2B, in rat heart. J Histochem Cytochem. 2007;55:795-804 pubmed
..Thus, SUR2A and SUR2B are not only the regulatory subunits of sarcolemmal K(ATP) channels but may also function as regulatory subunits in mitochondrial K(ATP) channels and play important roles in cardioprotection...
Zhou M, He H, Hirano M, Sekiguchi M, Tanaka O, Kawahara K, et al
. Localization of ATP-sensitive K+ channel subunits in rat submandibular gland. J Histochem Cytochem. 2010;58:499-507 pubmed publisher
..1, Kir6.2, SUR2A, and SUR2B, with various combinations of colocalization with each other, and may play important roles in rat SMG during salivary secretion...
Zhou M, Tanaka O, Suzuki M, Sekiguchi M, Takata K, Kawahara K, et al
. Localization of pore-forming subunit of the ATP-sensitive K(+)-channel, Kir6.2, in rat brain neurons and glial cells. Brain Res Mol Brain Res. 2002;101:23-32 pubmed
..2. Under the electron microscope, we showed in vivo for the first time that the immunoreactive products were localized in the endoplasmic reticulum and Golgi apparatus as well as the plasma membranes of neurons and glial cells. ..
Zhou M, He H, Suzuki R, Tanaka O, Sekiguchi M, Yasuoka Y, et al
. Expression of ATP sensitive K+ channel subunit Kir6.1 in rat kidney. Eur J Histochem. 2007;51:43-51 pubmed
..1 is mainly localized in the mitochondria, endoplasmic reticulum (ER), and very weakly in cell membranes. Thus, Kir6.1 is contained in the kidney and may be a candidate of mitochondrial K(ATP) channels. ..
Zhou M, He H, Tanaka O, Suzuki R, Sekiguchi M, Yasuoka Y, et al
. Localization of the sulphonylurea receptor subunits, SUR2A and SUR2B, in rat renal tubular epithelium. Tohoku J Exp Med. 2008;214:247-56 pubmed
..In conclusion, the regulatory subunits of the K(ATP) channel in the rat kidney are SUR2A and SUR2B; they also are candidate regulatory subunits for the mitochondrial K(ATP) channel...
Zhou M, He H, Tanaka O, Sekiguchi M, Kawahara K, Abe H. Different localization of ATP sensitive K+ channel subunits in rat testis. Anat Rec (Hoboken). 2011;294:729-37 pubmed publisher
..Different localizations of the K(ATP) channel subunits in the cell membrane and membranous organelles of spermatogenic cells and Sertoli cells indicated the complex and multiple functions of K(ATP) channels in rat testis...
Zhou M, He H, Tanaka O, Sekiguchi M, Kawahara K, Abe H. Localization of the ATP-sensitive K(+) channel regulatory subunits SUR2A and SUR2B in the rat brain. Neurosci Res. 2012;74:91-105 pubmed publisher