Y Sawaishi

Summary

Affiliation: Akita University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint Acute cerebellitis
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Akita City, Japan
    Cerebellum 1:223-8. 2002
  2. ncbi request reprint Positron emission tomography in juvenile Alexander disease
    Y Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    J Neurol Sci 165:116-20. 1999
  3. ncbi request reprint Migratory basal ganglia lesions in subacute sclerosing panencephalitis (SSPE): clinical implications of axonal spread
    Y Sawaishi
    The Department of Pediatrics, Akita University School of Medicine, Hondo 1 1 1, Akita, Japan
    J Neurol Sci 168:137-40. 1999
  4. doi request reprint Review of Alexander disease: beyond the classical concept of leukodystrophy
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
    Brain Dev 31:493-8. 2009
  5. ncbi request reprint A hippocampal lesion detected by high-field 3 tesla magnetic resonance imaging in a patient with temporal lobe epilepsy
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Tohoku J Exp Med 205:287-91. 2005
  6. ncbi request reprint Juvenile Alexander disease with a novel mutation in glial fibrillary acidic protein gene
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Neurology 58:1541-3. 2002
  7. ncbi request reprint Choroid plexus carcinoma presented with spinal dysfunction caused by a drop metastasis: a case report
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Akita, Japan
    J Neurooncol 63:75-9. 2003
  8. ncbi request reprint Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Japan
    Sleep 25:337-9. 2002
  9. ncbi request reprint Lidocaine-dependent early infantile status epilepticus with highly suppressed EEG
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Epilepsia 43:201-4. 2002
  10. ncbi request reprint [Symptomatic hypersomnia due to orexin deficiency in hypothalamic lesions]
    Takashi Kanbayashi
    Department of Psychiatry, Akita University School of Medicine
    No To Hattatsu 38:340-5. 2006

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Acute cerebellitis
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Akita City, Japan
    Cerebellum 1:223-8. 2002
    ..A timely assessment and appropriate choice of treatment, including surgical intervention when indicated, are key to improving the outcome of affected patients...
  2. ncbi request reprint Positron emission tomography in juvenile Alexander disease
    Y Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    J Neurol Sci 165:116-20. 1999
    ..Positron emission tomography with 18F-fluorodeoxyglucose demonstrated hypometabolism in the frontal white matter corresponding to the areas with leukodystrophy. However, the overlying gray matter preserved normal glucose metabolism...
  3. ncbi request reprint Migratory basal ganglia lesions in subacute sclerosing panencephalitis (SSPE): clinical implications of axonal spread
    Y Sawaishi
    The Department of Pediatrics, Akita University School of Medicine, Hondo 1 1 1, Akita, Japan
    J Neurol Sci 168:137-40. 1999
    ..The series of migratory legions, each of which was connected by axonal pathways originating from the substantia nigra, suggests axonal spread of the SSPE virus...
  4. doi request reprint Review of Alexander disease: beyond the classical concept of leukodystrophy
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
    Brain Dev 31:493-8. 2009
    ..Except for a few mutations, no clear phenotype-genotype correlation has been established for Alexander disease, although male preponderance in the infantile type suggests that phenotypes may be partly affected by gender...
  5. ncbi request reprint A hippocampal lesion detected by high-field 3 tesla magnetic resonance imaging in a patient with temporal lobe epilepsy
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Tohoku J Exp Med 205:287-91. 2005
    ..This is the first report detecting a hippocampal lesion by 3 T MRI, which could not be found by conventional 1.5 T MRI...
  6. ncbi request reprint Juvenile Alexander disease with a novel mutation in glial fibrillary acidic protein gene
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Neurology 58:1541-3. 2002
    ..The authors discuss similar molecular mechanisms in another intermediate filament disease and propose a possible molecular pathogenesis in juvenile Alexander disease...
  7. ncbi request reprint Choroid plexus carcinoma presented with spinal dysfunction caused by a drop metastasis: a case report
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Akita, Japan
    J Neurooncol 63:75-9. 2003
    ..This report shows that CPC can develop exophytically in the subarachnoid space as well as in the ventricle simultaneously before appearance of clinical symptoms and confirms the importance of extensive neuroimaging in its evaluation...
  8. ncbi request reprint Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Japan
    Sleep 25:337-9. 2002
    ..In this study, we measured CSF hypocretin-1 levels in various age ranges from infants to elder people to investigate the age-dependent change of hypocretin concentrations...
  9. ncbi request reprint Lidocaine-dependent early infantile status epilepticus with highly suppressed EEG
    Yukio Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    Epilepsia 43:201-4. 2002
    ..Repeatedly all the abnormal findings improved in a lidocaine-dependent manner. Given the pharmacologic mechanisms of lidocaine as a sodium channel blocker, we speculate that our patient had a sodium channel dysfunction...
  10. ncbi request reprint [Symptomatic hypersomnia due to orexin deficiency in hypothalamic lesions]
    Takashi Kanbayashi
    Department of Psychiatry, Akita University School of Medicine
    No To Hattatsu 38:340-5. 2006
    ..The features of nocturnal sleep and EDS in symptomatic hypersomnia are more similar to idiopathic hypersomnia than to narcolepsy...
  11. ncbi request reprint [A case of carbamazepine intoxication with alpha coma and status epilepticus]
    A Ono
    Department of Pediatrics, Akita University School of Medicine, Akita
    No To Hattatsu 33:528-32. 2001
    ..Early diagnosis and appropriate treatments should improve the prognosis of carbamazepine intoxication...
  12. ncbi request reprint Immunoliposome-mediated gene transfer into cultured myotubes
    Y Watanabe
    Department of Pediatrics, Akita University School of Medicine, Japan
    Tohoku J Exp Med 192:173-80. 2000
    ..These results suggest that laminin B2 is not effective in enhancing the efficiency of gene transfection for non-proliferating myotubes. A specific antibody for surface antigen other than laminin B2 should be chosen in further studies...
  13. ncbi request reprint Fluctuation of computed tomographic findings in white matter in Alexander's disease
    Takashi Shiihara
    Department of Pediatrics, Yamagata University School of Medicine, Japan
    J Child Neurol 17:227-30. 2002
    ..Fluctuation of CT findings in white matter may reflect blood-brain barrier dysfunction in Alexander's disease...
  14. ncbi request reprint Asymptomatic hereditary Alexander's disease caused by a novel mutation in GFAP
    Takashi Shiihara
    Department of Pediatrics, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
    J Neurol Sci 225:125-7. 2004
    ..To elucidate the genotype-phenotype correlation in Alexander's disease, molecular diagnosis and MRI examination are required for many patients and their families...
  15. ncbi request reprint CSF hypocretin-1 (orexin-A) levels in childhood narcolepsy and neurologic disorders
    J Arii
    Department of Pediatrics, Chiba Rosai Hospital, 2 16 Tatsumidai higashi, Ichihara shi, Chiba 290 0003, Japan
    Neurology 63:2440-2. 2004
  16. ncbi request reprint Congenital hypomyelination neuropathy: decreased expression of the P2 protein in peripheral nerve with normal DNA sequence of the coding region
    Y Sawaishi
    Department of Pediatrics, Akita University School of Medicine, Japan
    J Neurol Sci 134:150-9. 1995
    ..Further investigation including the analysis of promoter region of P2 protein gene is needed to elucidate the mechanism of congenital hypomyelination neuropathy...
  17. ncbi request reprint Mutations of the NOG gene in individuals with proximal symphalangism and multiple synostosis syndrome
    T Takahashi
    Department of Pediatrics, Akita University School of Medicine, Akita, Japan
    Clin Genet 60:447-51. 2001
    ..386T>A (L129X) in a familial case of symphalangism, and a g.58delC (frameshift) in a family with multiple synostosis syndrome. Characteristic genotype-phenotype correlations have not been recognized from the mutations in the NOG gene...
  18. ncbi request reprint TRH therapy in a patient with juvenile Alexander disease
    Keiko Ishigaki
    Tokyo Women s Medical University, School of Medicine, Department of Pediatrics, 8 1 Kawadacho, 162 8666 Shinjuku ku, Tokyo, Japan
    Brain Dev 28:663-7. 2006
    ..Juvenile Alexander disease was diagnosed by genetic analysis, which detected a novel GFAP mutation, D360V. We also describe our clinical success in treating this patient with thyrotropin releasing hormone (TRH)...
  19. ncbi request reprint Periaxin mutation in Japanese patients with Charcot-Marie-Tooth disease
    Tesshu Otagiri
    Department of Pediatrics, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
    J Hum Genet 51:625-8. 2006
    ..Therefore, the high frequency of the R1070X mutation among the Japanese population is not likely the consequence of a founder effect, but probably a result of a mutation hot spot...
  20. doi request reprint Nationwide survey (incidence, clinical course, prognosis) of Rasmussen's encephalitis
    Ayako Muto
    Department of Pediatrics, Tokyo Women s Medical University, Tokyo, Japan
    Brain Dev 32:445-53. 2010
    ..We performed a nationwide survey of RE to assess the clinical picture, treatment effect, and prognosis of Japanese RE patients...
  21. ncbi request reprint Leukoencephalopathy around a tumor cyst following intracystic methotrexate injection
    Tamami Yano
    Department of Reproductive and Developmental Medicine, Division of Pediatrics, Akita University School of Medicine, Akita, Japan
    Pediatr Neurol 32:68-71. 2005
    ....
  22. pmc Pharmacokinetics and effects of ribavirin following intraventricular administration for treatment of subacute sclerosing panencephalitis
    Mitsuaki Hosoya
    Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan
    Antimicrob Agents Chemother 48:4631-5. 2004
    ..Intraventricular ribavirin therapy should be pursued further for its potential use for patients with SSPE and might be applied in the treatment of patients with encephalitis caused by other RNA viruses...
  23. ncbi request reprint Periaxin mutation causes early-onset but slow-progressive Charcot-Marie-Tooth disease
    Kazuki Kijima
    Department of Pediatrics, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
    J Hum Genet 49:376-9. 2004
    ..Mutations lacking the carboxyl-terminal acidic domain may show loss-of-function effects and cause severe demyelinating CMT...
  24. ncbi request reprint Mutations in the NHLRC1 gene are the common cause for Lafora disease in the Japanese population
    Shweta Singh
    Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India
    J Hum Genet 50:347-52. 2005
    ..Our study, in addition to documenting the genetic and molecular heterogeneity observed for LD, suggests that mutations in the NHLRC1 gene may be a common cause of LD in the Japanese population...