Katsuyuki Murata

....

..The purpose of this study was to determine the effects of shift work on heart rate-corrected QT (QTc) and blood pressure in relation to heart rate variability (CV(RR))...

..In light of the precautionary principle, a conclusion on health effects of low-level dietary exposures to methylmercury needs to be drawn from all available data including the New Zealand study...

....

..We examined whether the BMD approach can be applied to epidemiological endpoints with clinical standards...

..The subclinical effects of prenatal exposure to methylmercury from fish consumption on the cardiac autonomic function were assessed in 136 Japanese 7-year-old children recruited for this study...

....

..5) Since some developing countries appear to be in similar situations to Japan in the past, attention should be directed toward early recognition of a risky agent and precautions should be taken against it...

..The objectives of this article were to present an overview of neurophysiological findings involved in methylmercury neurotoxicity and to examine the usefulness of those measures...

..The influence of genetics on surgery-induced hyperglycemia remains only partially understood...

..Because umbilical cord blood has been used for cord-blood stem cell transplants, dry umbilical cord tissue should be effectively utilized for the advancement of medical sciences...

..Rather, long-term exposure to methylmercury may pose a potential risk for cardiac events involving sympathovagal imbalance among fish-consuming populations...

....

..A change in vulnerability to MeHg toxicity is suggested by the apparent sensitivity of the peak III-V component to recent MeHg exposure...

..Also, the following equation may be applicable to the population neither with dental amalgam fillings nor with occupational exposures: [hair mercury (microg/g)]=2.44x[toenail mercury (microg/g)]...

..The results of this cohort study will allow us to evaluate associations between the neurobehavioral development of children and perinatal exposures to MeHg and environmentally POPs in Japan...

..Cancer cells reportedly produce C-reactive protein (CRP) locally within tumors. The aim of this study was to determine whether tumoral CRP is associated with clinical outcome and recurrence in thoracic esophageal squamous cell cancer...

..Further studies are required to clarify at which period of exposure during gestation the cord mercury concentration represents in relation to mercury concentrations in maternal segmental hair...

..In conclusion, the absence of spontaneous awakening from nocturnal sleep in preschool children is suggested to be characterized by short sleep duration, parasympathetic hypoactivity, and elevated heart rate...

..05), which may have been due to the acute effects of such solvents. These findings suggest that long-term exposure to mixed organic solvents may impair neuromotor functions as measured by postural sway and tremor...

..To clarify the neuromotor effects of occupational exposure to mercury vapor, hand tremor and postural sway were measured in 27 miners and smelters (i.e., exposed workers) and 52 unexposed subjects...

....

..Despite the presence of potential selection bias, it is suggested that shift work in nurses may cause not only a long-term sympathodominant state but also some neuromotor impairment...

..The discrepancy between the two conclusions is also discussed...

..Such critical doses are necessary to promote preventive activities of adverse effects of lead...

..To minimize this risk in Japan, use of biological safety cabinet and appropriate protective equipment, in addition to staff education and training, should be implemented in the healthcare environment...

..This finding suggest the importance of consistency in chemical analysis and the necessity for quality and accuracy control using reference materials...

....

....

..The benchmark results using evoked potential latencies are in close agreement with results based on neuropsychological test performance...

..The objective was to clarify the effect of alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase 2 (ALDH2) genotypes on the diabetic risk in Japanese workers...

..To investigate whether sleep disturbances during pregnancy affect cardiac autonomic modulation in the resting state...

..Along with more recent epidemiological studies of children with environmental arsenic exposures, the data amply demonstrate the need to consider neurotoxicity as a key concern in risk assessment of inorganic arsenic exposure...

..These findings suggest that sleep duration in preschool children is associated with SBP, and extremely short or long sleep may invite subclinical health problems...

..0052), lumbar kyphosis (p = 0.0057), spinal inclination (p = 0.0378), mobility of lumbar spine (0.027), and mobility of spinal inclination (p = 0.0282) were significantly associated with presence/absence of falls in elderly individuals...

..These findings suggest that the BMDL and BMD correspond to the NOAEL and lowest-observed-adverse-effect level, respectively, if the sample number of clinical data is large enough to confirm the dose-response association...

..We suggest that sleep duration is an important predictor for autonomic development in childhood...

..The data of this study can be used as K6 benchmark values, which enhance the significance of future corporate health risk appraisal surveys...

..It is suggested that hepatocellular injury (i.e., AST elevation) in Japanese men may emerge at the ethanol level of more than 50 g/day...

..Also, these parameters should be analyzed in men and women separately...

..Our aim in this study was to assess whether cytokine polymorphisms were associated with infectious complications following esophagectomy in a Japanese population...