Takashi Kanbayashi

Summary

Affiliation: Akita University School of Medicine
Country: Japan

Publications

  1. ncbi request reprint CSF hypocretin-1 (orexin-A) concentrations in narcolepsy with and without cataplexy and idiopathic hypersomnia
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Akita
    J Sleep Res 11:91-3. 2002
  2. ncbi request reprint Hypocretin-1 (orexin-A) concentrations in cerebrospinal fluid are low in patients with Guillain-Barré syndrome
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Japan
    Psychiatry Clin Neurosci 56:273-4. 2002
  3. pmc CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Sleep 32:181-7. 2009
  4. ncbi request reprint Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Japan
    Sleep 25:337-9. 2002
  5. doi request reprint The pathophysiologic basis of secondary narcolepsy and hypersomnia
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Curr Neurol Neurosci Rep 11:235-41. 2011
  6. doi request reprint Alcohol has a dose-related effect on parasympathetic nerve activity during sleep
    Yohei Sagawa
    Department of Neuropsychiatry, Akita University, School of Medicine, Akita, Japan
    Alcohol Clin Exp Res 35:2093-100. 2011
  7. doi request reprint Symptomatic narcolepsy in patients with neuromyelitis optica and multiple sclerosis: new neurochemical and immunological implications
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita City, Japan
    Arch Neurol 66:1563-6. 2009
  8. pmc Anti-NMDA-receptor antibody detected in encephalitis, schizophrenia, and narcolepsy with psychotic features
    Ko Tsutsui
    Akita University, Department of Neuropsychiatry, Akita, Japan
    BMC Psychiatry 12:37. 2012
  9. ncbi request reprint Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects
    Takashi Kanbayashi
    Department of Psychiatry, Akita University School of Medicine, Akita, Japan
    Psychiatry Clin Neurosci 56:307-8. 2002
  10. ncbi request reprint Total sleep deprivation elevates blood pressure through arterial baroreflex resetting: a study with microneurographic technique
    Yuriko Ogawa
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Sleep 26:986-9. 2003

Collaborators

Detail Information

Publications38

  1. ncbi request reprint CSF hypocretin-1 (orexin-A) concentrations in narcolepsy with and without cataplexy and idiopathic hypersomnia
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Akita
    J Sleep Res 11:91-3. 2002
    ..Low CSF hypocretin-1 is therefore very specific for HLA DR2 positive narcolepsy-cataplexy, and the deficiency is likely to be established at the early stage of the disease...
  2. ncbi request reprint Hypocretin-1 (orexin-A) concentrations in cerebrospinal fluid are low in patients with Guillain-Barré syndrome
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Japan
    Psychiatry Clin Neurosci 56:273-4. 2002
    ..The results of the present study indicate that some patients with GBS have lower levels of CSF hypocretin-1...
  3. pmc CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Sleep 32:181-7. 2009
    ....
  4. ncbi request reprint Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Hondo, Japan
    Sleep 25:337-9. 2002
    ..In this study, we measured CSF hypocretin-1 levels in various age ranges from infants to elder people to investigate the age-dependent change of hypocretin concentrations...
  5. doi request reprint The pathophysiologic basis of secondary narcolepsy and hypersomnia
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Curr Neurol Neurosci Rep 11:235-41. 2011
    ..Further studies of the involvement of the hypocretin system in symptomatic narcolepsy and EDS are helpful to understand the pathophysiologic mechanisms for occurrence of EDS and cataplexy...
  6. doi request reprint Alcohol has a dose-related effect on parasympathetic nerve activity during sleep
    Yohei Sagawa
    Department of Neuropsychiatry, Akita University, School of Medicine, Akita, Japan
    Alcohol Clin Exp Res 35:2093-100. 2011
    ..The aim of this study was to identify the acute effects of ethanol on the relationship between sleep and heart rate variability (HRV) during sleep...
  7. doi request reprint Symptomatic narcolepsy in patients with neuromyelitis optica and multiple sclerosis: new neurochemical and immunological implications
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, Akita City, Japan
    Arch Neurol 66:1563-6. 2009
    ..To characterize factors that contribute to symptomatic narcolepsy and excessive daytime sleepiness in neuromyelitis optica and multiple sclerosis...
  8. pmc Anti-NMDA-receptor antibody detected in encephalitis, schizophrenia, and narcolepsy with psychotic features
    Ko Tsutsui
    Akita University, Department of Neuropsychiatry, Akita, Japan
    BMC Psychiatry 12:37. 2012
    ..These symptoms often occur in young females with ovarian teratomas and are frequently associated with serum and CSF autoantibodies to the NMDA receptor (NMDAR)...
  9. ncbi request reprint Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects
    Takashi Kanbayashi
    Department of Psychiatry, Akita University School of Medicine, Akita, Japan
    Psychiatry Clin Neurosci 56:307-8. 2002
    ..The results indicated that the percentage of rapid eye movement sleep to total sleep time was increased significantly by a single dose of 5 mg of donepezil when given to healthy subjects immediately before retiring to bed...
  10. ncbi request reprint Total sleep deprivation elevates blood pressure through arterial baroreflex resetting: a study with microneurographic technique
    Yuriko Ogawa
    Department of Neuropsychiatry, Akita University School of Medicine, Akita, Japan
    Sleep 26:986-9. 2003
    ....
  11. ncbi request reprint Sleep habits of students attending elementary schools, and junior and senior high schools in Akita prefecture
    Takaubu Takemura
    Department of Psychiatry, Akita University School of Medicine, Akita City, Japan
    Psychiatry Clin Neurosci 56:241-2. 2002
    ..In particular, approximately half of the students attending senior high schools answered that they slept 6 h or less on weekdays and nodded off during classes more than twice a week...
  12. ncbi request reprint A psychological study on patients with masticatory muscle disorder and sleep bruxism
    Takaubu Takemura
    Dept of Neuropsychiatry, Akita University School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
    Cranio 24:191-6. 2006
    ..Consequently, they are unable to demonstrate adequate self-assertiveness in stressful situations...
  13. ncbi request reprint [Symptomatic hypersomnia due to orexin deficiency in hypothalamic lesions]
    Takashi Kanbayashi
    Department of Psychiatry, Akita University School of Medicine
    No To Hattatsu 38:340-5. 2006
    ..The features of nocturnal sleep and EDS in symptomatic hypersomnia are more similar to idiopathic hypersomnia than to narcolepsy...
  14. ncbi request reprint Acute effects of zolpidem on daytime alertness, psychomotor and physical performance
    Sachiko Uemura Ito
    Akita University, School of Health Sciences, Course of Physical Therapy 1 1 1 Hondo, Akita, Akita 0108543, Japan
    Neurosci Res 59:309-13. 2007
    ....
  15. ncbi request reprint Niemann-Pick disease type C: cataplexy and hypocretin in cerebrospinal fluid
    Katsuyuki Oyama
    Department of Pediatrics, Akita University School of Medicine, Akita, Japan
    Tohoku J Exp Med 209:263-7. 2006
    ..All of the NPC cases with cataplexy demonstrated low levels of CSF hypocretin-1, confirming the association of reduced CSF hypocretin-1 levels with cataplexy in NPC...
  16. ncbi request reprint A case of mild Alzheimer's disease accompanied by periodic synchronous discharges
    Hiroyasu Ishikawa
    Department of Psychiatry, Akita University School of Medicine, Akita, Japan
    Clin EEG Neurosci 35:165-7. 2004
    ..We recently encountered a patient with mild AD accompanied by transient PSD. To our knowledge, this is the first case report to suggest that PSD can occur in mild AD...
  17. ncbi request reprint [Recent advance of treatments for narcolepsy and hypersomnia]
    Takashi Kanbayashi
    Department of Neuropsychiatry, Akita University School of Medicine, 1 1 1 Hondo, Akita, 010 8543 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 29:109-13. 2009
    ..H3 receptors are auto receptors located in the brain histamine neuron, and agonists act for suppression, antagonists for activation. They have shown good results in the animal experiments and phase 2 of clinical experiments...
  18. ncbi request reprint A case of acute disseminated encephalomyelitis presenting hypersomnia with decreased hypocretin level in cerebrospinal fluid
    Hiroaki Kubota
    Chiba Children s Hospital, Department of Pediatrics, Graduate School of Medicine, Chiba University, Japan
    J Child Neurol 17:537-9. 2002
    ..This case suggests that the arousal state control mechanism related to the hypocretin peptide/receptor system may be impaired in some patients with acute disseminated encephalomyelitis...
  19. ncbi request reprint Does CSF hypocretin-1 decrease in Bickerstaff's brainstem encephalitis?
    Naoki Saji
    Clin Neurol Neurosurg 109:547-8. 2007
  20. ncbi request reprint Narcolepsy without cataplexy: 2 subtypes based on CSF hypocretin-1/orexin-A findings
    Yasunori Oka
    Department of Neurology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawaharacho, Sakyo ku, 606 8507 Kyoto, Japan
    Sleep 29:1439-43. 2006
    ..Our aim was to examine whether clinical characteristics vary with CSF hypocretin-1 levels among narcoleptic patients without cataplexy...
  21. ncbi request reprint Parkinson's disease comorbid with narcolepsy presenting low CSF hypocretin/orexin level
    Tetsuya Maeda
    Sleep Med 7:662. 2006
  22. ncbi request reprint CSF orexin levels of Parkinson's disease, dementia with Lewy bodies, progressive supranuclear palsy and corticobasal degeneration
    Kenichi Yasui
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    J Neurol Sci 250:120-3. 2006
    ..These findings suggest that loss of orexin neurons or impaired orexin neurotransmission might exist as a part of the neurodegeneration associated with advanced PSP with long duration of morbidity...
  23. ncbi request reprint Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects
    Rika Aizawa
    Japanese Red Cross Junior College of Akita, Akita City, Japan
    Psychiatry Clin Neurosci 56:303-4. 2002
    ..There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines...
  24. ncbi request reprint Hypersomnia and low CSF hypocretin-1 (orexin-A) concentration in a patient with multiple sclerosis showing bilateral hypothalamic lesions
    Takashi Kato
    Department of Neurology, Toyoshina Red Cross Hospital, Nagano
    Intern Med 42:743-5. 2003
    ..These findings suggest that the hypothalamic hypocretin (orexin) system may be crucial to maintaining the arousal level and that lesions in the system can cause hypersomnia in MS...
  25. ncbi request reprint [Orexin nervous system and narcolepsy]
    Hideaki Kondo
    Nihon Naika Gakkai Zasshi 95:748-55. 2006
  26. ncbi request reprint Decreased cerebrospinal fluid hypocretin-1 levels near the onset of narcolepsy in 2 prepubertal children
    Hiroaki Kubota
    Division of Neurology, Chiba Children s Hospital, Chiba, Japan
    Sleep 26:555-7. 2003
    ..Measurement of hypocretin-1 levels in the cerebrospinal fluid is useful for the early diagnosis of narcolepsy with prepubertal onset...
  27. ncbi request reprint [A six year-old case of narcolepsy]
    Yukiharu Fujii
    Department of Pediatric Neurology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo
    No To Hattatsu 35:505-10. 2003
    ..The CSF orexin level was far below the lower limit of the control values. It is very useful to measure CSF orexin for the diagnosis of early onset narcolepsy...
  28. ncbi request reprint [Excessive daytime sleepiness and low CSF orexin-A/hypocretin-I levels in a patient with probable progressive supranuclear palsy]
    Yuko Hattori
    Honmachi Neurological Clinic, 3 20 29 Sakae, Naka ku, Nagoya City 460 0008, Japan
    No To Shinkei 55:1053-6. 2003
    ..In our patient, the treatment with methylphenidate HCl was effective on EDS...
  29. ncbi request reprint FOS expression in orexin neurons following muscimol perfusion of preoptic area
    Shinsuke Satoh
    Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka 569 8686, Japan
    Neuroreport 15:1127-31. 2004
    ..018 by Wilcoxon signed-rank test). These results suggest that subpopulations of the preoptic neurons give an inhibitory tone to the activities of the orexin neurons in the perifornical/lateral hypothalamic areas...
  30. ncbi request reprint Low CSF hypocretin-1/orexin-A associated with hypersomnia secondary to hypothalamic lesion in a case of multiple sclerosis
    Yasunori Oka
    J Neurol 251:885-6. 2004
  31. ncbi request reprint Hypersomnia and low cerebrospinal fluid hypocretin levels in acute disseminated encephalomyelitis
    Sosuke Yoshikawa
    Department of Pediatrics, Osaka Medical College, Osaka, Japan
    Pediatr Neurol 31:367-70. 2004
    ..Decreased hypothalamic hypocretin neurotransmission may be involved in this symptomatic case of hypersomnia associated with acute disseminated encephalomyelitis...
  32. ncbi request reprint Hypersomnia, asterixis and cataplexy in association with orexin A-reduced hypothalamic tumor
    Kazuya Nokura
    J Neurol 251:1534-5. 2004
  33. ncbi request reprint [Nacrolepsy manifesting initially as cataplexy and sleep paralysis: usefulness of CSF hypocretin-1 examination for early diagnosis]
    Yuka Kobayashi
    Department of Neurology, Dokkyo University School of Medicine
    Rinsho Shinkeigaku 42:233-6. 2002
    ..A delay in diagnosis, however, may produce personal and social problems for narcoleptic patients. We believe that an examination of CSF hypocretin-1 aids in the early diagnosis of narcolepsy...
  34. ncbi request reprint Hypersomnia caused by isolated angiitis of the CNS
    Kayoko Nakaji
    Department of Neurology, Kyoto University Graduate School of Medicine, Japan
    Intern Med 44:883-5. 2005
    ..Orexin A in the CSF was decreased. Hypersomnia and a decrease of the CNS orexin A improved after corticosteroid therapy. Hypersomnia can be an initial symptom of IAC if it involves the hypothalamus...
  35. ncbi request reprint [An old and new focal symptom, hypothalamus and hypersomnia, orexin system and narcolepsy]
    Takashi Kanbayashi
    Rinsho Shinkeigaku 45:824-7. 2005
  36. ncbi request reprint Expression pattern of FOS in orexin neurons during sleep induced by an adenosine A2A receptor agonist
    Shinsuke Satoh
    Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka 569 8686, Japan
    Behav Brain Res 170:277-86. 2006
    ..MCH neurons are not likely to change their activities during this sleep-promoting process...
  37. ncbi request reprint Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system
    Seiji Nishino
    Center for Narcolepsy, Stanford University, Palo Alto, CA 94304, USA
    Sleep Med Rev 9:269-310. 2005
    ..It appears that further studies of the involvement of the hypocretin system in symptomatic narcolepsy and EDS are helpful to understand the pathophysiological mechanisms for the occurrence of EDS and cataplexy...
  38. ncbi request reprint Diazepam reduces both arterial blood pressure and muscle sympathetic nerve activity in human
    Tsuyoshi Kitajima
    Department of Psychiatry, Fujita Health University School of Medicine, 1 98 Dengakugakubo, Kutsukake cho, Toyoake City, Aichi 470 1192, Japan
    Neurosci Lett 355:77-80. 2004
    ..We concluded that the hypotensive effect of diazepam in human is mainly due to the central mechanism...