Research Topics
| Naoki AikawaSummaryCountry: Japan Publications
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Detail Information
Publications
Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trialNaoki Aikawa
Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan
Shock 35:349-54. 2011..Mortality rates of patients who recovered from DIC were 3.7% (1/27) in the TM-α group and 15% (3/20) in the heparin group. These results suggest TM-α may be valuable in the treatment of DIC associated with infection...
Clinical effects of micafungin, a novel echinocandin antifungal agent, on systemic fungal infections in surgery, emergency, and intensive-care medicine: evaluation using the AKOTT algorithmNaoki Aikawa
Emergency and Critical Care Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
J Infect Chemother 15:219-27. 2009....
Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV studyNaoki Aikawa
Department of Emergency and Critical Care Medicine, Keio University School of Medicine, 35 Shinano machi, Shinjuku ku, Tokyo, Japan
Pulm Pharmacol Ther 24:549-54. 2011..The Pharmaceuticals and Medical Devices Agency (PMDA) has ordered to conduct a postmarket clinical study in order to reevaluate the efficacy and safety of Sivelestat in actual clinical settings in Japan...
[Influence of the diagnosis and treatment guidelines for mycosis profunda (deep mycosis) in the field of emergency and critical care medicine--the influences of conformity and non-conformity to the guidelines on the outcomes of patients]Shigeto Oda
Department of Emergency and Critical Care Medicine, Chiba University School of Medicine, Japan
Jpn J Antibiot 61:29-41. 2008....
Application of the recent American practice resources for risk stratification system for patients presenting to a Japanese emergency department because of syncopeMasaru Suzuki
Department of Emergency Medicine, Keio University, Tokyo, Japan
Int Heart J 48:513-22. 2007..The objective of the present study was to determine if risk stratification using these practice resources is valid in a series of Japanese patients...
[Efficacy of micafungin sodium on fungal infection in critical care]Yoshihisa Tateishi
Department of Emergency and Critical Care Medicine, Graduate School of Medicine, Chiba University, Japan
Nippon Ishinkin Gakkai Zasshi 47:293-7. 2006..The drug was well tolerated and discontinuation of its treatment due to adverse events was not experienced during the study period...
Current status of diagnosis and treatment of invasive fungal infections in Japan: the influence of the new Japanese guidelinesNaoki Aikawa
Keio University Hospital, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
J Infect Chemother 11:278-87. 2005..Definitive diagnoses of invasive fungal infection are too scarce at the national level. The cooperation of clinicians for organizing more definitive diagnoses would be appreciated when the guidelines are revised...
Long-term survival of Japanese patients transported to an emergency department because of syncopeMasaru Suzuki
Department of Emergency Medicine, School of Medicine, Keio University, Tokyo, Japan
Ann Emerg Med 44:215-21. 2004..81 [95% CI 1.53 to 5.16], 18.74 [95% CI 5.90 to 59.52]). CONCLUSION: Cardiac syncope is associated with higher mortality than noncardiac syncope in this Japanese patient population...
Thrombolysis candidates for the treatment of stroke at an emergency department in JapanKeiji Yamaguchi
Department of Emergency Medicine, School of Medicine, Keio University, Tokyo, Japan
Acad Emerg Med 9:754-8. 2002..38% among all ED patients. CONCLUSIONS: The number of potential IV-tPA candidates among patients transported to the ED by ambulance in Japan was substantial, where the proportion of embolic infarction cases was extremely high...
Characteristics of elderly patients presenting to the emergency department with injuryWilliam Ng
Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
Keio J Med 51:11-6. 2002..This information would be useful in the planning of injury prevention programs, with particular emphasis on elderly females and MVA-unrelated trauma...
Population pharmacokinetics of Arbekacin in patients infected with methicillin-resistant Staphylococcus aureusYusuke Tanigawara
Department of Hospital Pharmacy, School of Medicine, Keio University, Tokyo 160 8582, Japan
Antimicrob Agents Chemother 50:3754-62. 2006..3 liters in patients with sepsis. The population pharmacokinetic parameters of arbekacin obtained here are useful for optimal use of this aminoglycoside in the treatment of MRSA-infected patients...
Multicenter prospective study of procalcitonin as an indicator of sepsisNaoki Aikawa
Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Keio University Hospital, 35 Shinanomachi, Shinjuku ku, Tokyo, 160 8582, Japan
J Infect Chemother 11:152-9. 2005..2%, while that of blood culture was 42.6%. PCT is thus essential for discriminating bacterial infection from SIRS, and is superior in this respect to conventional serum markers and blood culture...
[Influence of the diagnosis and treatment guidelines for mycosis profunda (deep mycosis) in the field of emergency and critical care medicine--with reference to patient background]Hideki Ishikawa
Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Japan
Jpn J Antibiot 61:18-28. 2008....
[Compulsory postgraduate clinical training and surgical education]Naoki Aikawa
Department of Emergency and Critical Care Medicine, School of Medicine, Keio University, Tokyo, Japan
Nippon Geka Gakkai Zasshi 104:280-4. 2003..In accordance with the introduction of new system, the current surgical training system is to be renovated and the terms for surgical trainees to be eligible for surgical specialty boards must be reviewed...
