Kenji Wakai

Summary

Affiliation: Aichi Cancer Center
Country: Japan

Publications

  1. ncbi request reprint The JICA Training Course, Community-Based Cancer Prevention for Asian Pacific Countries, 2004 (Epidemiological approach)
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Asian Pac J Cancer Prev 5:231-6. 2004
  2. ncbi request reprint Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: effect modification by sex for carotenoids
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Institute, Nagoya 464 8681, Japan
    Nutr Cancer 51:13-24. 2005
  3. ncbi request reprint Dietary fiber and risk of colorectal cancer in the Japan collaborative cohort study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 16:668-75. 2007
  4. ncbi request reprint Alcohol drinking and lung cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 37:168-74. 2007
  5. ncbi request reprint A scoring system to predict renal outcome in IgA nephropathy: from a nationwide prospective study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Nephrol Dial Transplant 21:2800-8. 2006
  6. ncbi request reprint Tobacco smoking and lung cancer risk: an evaluation based on a systematic review of epidemiological evidence among the Japanese population
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 36:309-24. 2006
  7. ncbi request reprint Dietary risk factors for colon and rectal cancers: a comparative case-control study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 16:125-35. 2006
  8. ncbi request reprint Updated information on risk factors for lung cancer: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
    J Epidemiol 15:S134-9. 2005
  9. ncbi request reprint The JICA training course, community-based cancer prevention for the Asian Pacific countries, fiscal years 2004 and 2005 (epidemiological approach)
    Kenji Wakai
    Aichi Cancer Center Research Institute, Chikusa ku, Nagoya 464 8681, Japan
    Asian Pac J Cancer Prev 7:5-10. 2006
  10. ncbi request reprint Alcohol consumption and colorectal cancer risk: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 15:S173-9. 2005

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint The JICA Training Course, Community-Based Cancer Prevention for Asian Pacific Countries, 2004 (Epidemiological approach)
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Asian Pac J Cancer Prev 5:231-6. 2004
  2. ncbi request reprint Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: effect modification by sex for carotenoids
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Institute, Nagoya 464 8681, Japan
    Nutr Cancer 51:13-24. 2005
    ..010) and 0.29 (0.07-1.17; trend P = 0.098), respectively. The effects of some carotenoids on colorectal cancer risk may be modified by sex or by factors associated with sex, including smoking and drinking habits...
  3. ncbi request reprint Dietary fiber and risk of colorectal cancer in the Japan collaborative cohort study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 16:668-75. 2007
    ..The role of dietary fiber in the prevention of colorectal cancer seems to remain inconsistent, and further investigations in various populations are warranted. (..
  4. ncbi request reprint Alcohol drinking and lung cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 37:168-74. 2007
    ..Based on a systematic review of epidemiologic evidence, we evaluated this association among the Japanese population, who may be more susceptible to alcohol-related diseases than Western populations...
  5. ncbi request reprint A scoring system to predict renal outcome in IgA nephropathy: from a nationwide prospective study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Nephrol Dial Transplant 21:2800-8. 2006
    ..Although there are several prognostic indicators, it remains difficult to predict the renal outcome in individual patients...
  6. ncbi request reprint Tobacco smoking and lung cancer risk: an evaluation based on a systematic review of epidemiological evidence among the Japanese population
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 36:309-24. 2006
    ..It would be of value, therefore, to quantify that association in Japan based on a systematic review of epidemiological evidence for the primary prevention of lung cancer...
  7. ncbi request reprint Dietary risk factors for colon and rectal cancers: a comparative case-control study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 16:125-35. 2006
    ..In Japan, the incidence rate of colon cancer has more rapidly increased than that of rectal cancer. The differential secular trends may be due to different dietary factors in the development of colon and rectal cancers...
  8. ncbi request reprint Updated information on risk factors for lung cancer: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
    J Epidemiol 15:S134-9. 2005
    ..Updated information on risk factors for lung cancer, therefore, is of great importance. The Japan Collaborative Cohort Study, a large prospective study started in 1988, has provided such information...
  9. ncbi request reprint The JICA training course, community-based cancer prevention for the Asian Pacific countries, fiscal years 2004 and 2005 (epidemiological approach)
    Kenji Wakai
    Aichi Cancer Center Research Institute, Chikusa ku, Nagoya 464 8681, Japan
    Asian Pac J Cancer Prev 7:5-10. 2006
    ....
  10. ncbi request reprint Alcohol consumption and colorectal cancer risk: findings from the JACC Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    J Epidemiol 15:S173-9. 2005
    ..Because alcohol drinking is a potential risk factor for colorectal cancer, the trend in alcohol consumption in Japan may partly explain the increase in incidence and mortality rates of this malignancy until 1990-1995...
  11. ncbi request reprint Intake frequency of fish and serum levels of long-chain n-3 fatty acids: a cross-sectional study within the Japan Collaborative Cohort Study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, Japan
    J Epidemiol 15:211-8. 2005
    ..Whether reported fish consumption reflects the fatty acid intake, however, has to be elucidated...
  12. ncbi request reprint Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Nagoya 464 8681, Japan
    Cancer Sci 96:590-9. 2005
    ..05-4.13). This prospective study did not support any increase in the risk of breast cancer associated with total or saturated fat intake, but it suggested the protective effects of the long-chain n-3 fatty acids that are abundant in fish...
  13. ncbi request reprint Trends in incidence of end-stage renal disease in Japan, 1983-2000: age-adjusted and age-specific rates by gender and cause
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Nephrol Dial Transplant 19:2044-52. 2004
    ..Trends in age-adjusted or age-specific incidence rates of end-stage renal disease (ESRD) have never been examined in Japan, a major ESRD epidemic area...
  14. ncbi request reprint Foods and beverages in relation to urothelial cancer: case-control study in Japan
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Urol 11:11-9. 2004
    ..The roles of several foods and beverages in the development of bladder cancer remain unclear...
  15. ncbi request reprint One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study
    Takeshi Suzuki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Sci 98:1439-46. 2007
    ..04), MTR A2756G (P = 0.04) and MTRR A66G (P = 0.03) polymorphisms. The results suggest that there may be interactions between one-carbon metabolism-related polymorphisms and alcohol drinking for HNSCC risk...
  16. ncbi request reprint No association between AICDA 7888 C/T polymorphism, Helicobacter pylori seropositivity, and the risk of atrophic gastritis and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Gastric Cancer 13:43-9. 2010
    ..We investigated the association of the AICDA 7888 C/T polymorphism with H. pylori infection and the risk of gastric cancer and atrophic gastritis in Japanese subjects...
  17. ncbi request reprint No association between MTHFR C677T and serum uric acid levels among Japanese with ABCG2 126QQ and SLC22A12 258WW
    Yukako Hinohara
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:93-100. 2013
    ..24) for CT genotype and OR=0.98 (0.84-1.32) for TT genotype, relative to CC genotype. The present study indicated no association between SUA and MTHFR C677T genotype, after the influences of ABCG2 Q126X and SLC22A12 W258X were removed...
  18. ncbi request reprint Alcohol dehydrogenase 2 His47Arg polymorphism influences drinking habit independently of aldehyde dehydrogenase 2 Glu487Lys polymorphism: analysis of 2,299 Japanese subjects
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 15:1009-13. 2006
    ..Heavy drinker status was also strongly associated with ADH2 Arg alleles. In conclusion, this study showed the strong effect of ADH2 His(47)Arg polymorphism on habitual drinking regardless of ALDH2 genotype...
  19. ncbi request reprint Risk of colorectal cancer is linked to erythrocyte compositions of fatty acids as biomarkers for dietary intakes of fish, fat, and fatty acids
    Kiyonori Kuriki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 15:1791-8. 2006
    ....
  20. ncbi request reprint A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Carcinogenesis 27:1018-23. 2006
    ..38, 0.80-2.38). In conclusion, while we failed to find any significant association with the ALDH2 polymorphism itself, significant interaction between ALDH2 and ADH2 polymorphism was observed. Replication in the future study is warranted...
  21. ncbi request reprint Tooth loss and intakes of nutrients and foods: a nationwide survey of Japanese dentists
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Community Dent Oral Epidemiol 38:43-9. 2010
    ..To clarify the association of tooth loss with dietary intakes among dentists, for whom sufficient dental care is available...
  22. doi request reprint Soy consumption reduces the risk of non-small-cell lung cancers with epidermal growth factor receptor mutations among Japanese
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Sci 99:1202-8. 2008
    ..023). In conclusion, soy consumption may exert a protective association against the development of NSCLCs with EGFR mutations, providing possible insights into mechanisms of their genesis...
  23. ncbi request reprint Smoking and colorectal cancer in a non-Western population: a prospective cohort study in Japan
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
    J Epidemiol 13:323-32. 2003
    ..The risk of colorectal cancer in relation to smoking habits has been examined mostly in Caucasians, and evidence for other ethnic groups is still scarce...
  24. doi request reprint Alcohol drinking and esophageal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Isao Oze
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 41:677-92. 2011
    ..We conclude that there is convincing evidence that alcohol drinking increases the risk of esophageal cancer in the Japanese population...
  25. ncbi request reprint Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan
    Akio Hiraki
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Cancer Sci 98:1087-91. 2007
    ....
  26. ncbi request reprint Smoking and serum CA19-9 levels according to Lewis and secretor genotypes
    Sayo Kawai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 123:2880-4. 2008
    ..When hemoglobin A1c was further adjusted, the association became stronger (p = 0.0027). In addition to polymorphic variations, some components of cigarette smoke may influence the production or destruction of CA19-9...
  27. doi request reprint Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Helicobacter 14:47-53. 2009
    ..We investigated the associations of TLR4+3725 G/C polymorphism, another functional polymorphism of TLR4, with risk of gastric cancer and gastric atrophy in Japanese...
  28. doi request reprint Significant association of RUNX3 T/A polymorphism at intron 3 (rs760805) with the risk of gastric atrophy in Helicobacter pylori seropositive Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Gastroenterol 44:1165-71. 2009
    ..pylori seropositivity and gastric atrophy in Japanese people...
  29. ncbi request reprint MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study
    Asahi Hishida
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Int Urol Nephrol 45:1613-20. 2013
    ..To clarify the associations of MTHFR, MTR, and MTRR polymorphisms with the risk of CKD in Japanese, we examined this association among Japanese subjects using cross-sectional data...
  30. ncbi request reprint Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and colorectal cancer risk in Japanese
    Kiyonori Kuriki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Sci 97:1226-35. 2006
    ....
  31. ncbi request reprint Applicability of allele/genotype frequency from documented controls for case-control studies on genotypes among Japanese: MTHFR C677T as an example
    Kenta Iida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 10:231-6. 2009
    ....
  32. ncbi request reprint A prospective study of reproductive and menstrual factors and colon cancer risk in Japanese women: findings from the JACC study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Cancer Sci 95:602-7. 2004
    ....
  33. ncbi request reprint Effect of dietary antioxidants and risk of oral, pharyngeal and laryngeal squamous cell carcinoma according to smoking and drinking habits
    Takeshi Suzuki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
    Cancer Sci 97:760-7. 2006
    ..These findings suggest that dietary antioxidant intake prevents HNSCC in smokers and drinkers...
  34. ncbi request reprint DPP4 genetic variants influence baseline prostate-specific antigen levels: the J-MICC study
    Takahiro Higashibata
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 75:73-80. 2013
    ..006), compared with the most common haplotype, T-A. In summary, our study suggests that DPP4 genetic variants influence baseline PSA levels, especially in men aged between 60 and 69...
  35. ncbi request reprint Diet and colorectal cancer mortality: results from the Japan Collaborative Cohort Study
    Masayo Kojima
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho, Nagoya, Japan
    Nutr Cancer 50:23-32. 2004
    ..Further investigation is therefore necessary to confirm the association between diet and colorectal cancer, especially by subsites and gender...
  36. ncbi request reprint Serum folate and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism adjusted for folate intake
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    J Epidemiol 18:125-31. 2008
    ..Since studies considering folate intake are limited, we examined the association between folate intake and serum folate levels, according to the genotype...
  37. doi request reprint PRKCH gene polymorphism is associated with the risk of severe gastric atrophy
    Yasuyuki Goto
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, 466 8550, Japan
    Gastric Cancer 13:90-4. 2010
    ..To elucidate its applicability in the development of GA and GC, this study aimed to investigate the associations of the PRKCH polymorphism with the risks of GA and GC...
  38. pmc Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Gastroenterol 9:51. 2009
    ....
  39. doi request reprint Significant association of urokinase plasminogen activator Pro141Leu with serum lipid profiles in a Japanese population
    Takashi Tamura
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Gene 524:363-7. 2013
    ..11 (95%CI; 1.00-1.23) and 1.16 (95%CI; 1.03-1.30) for those with Leu allele relative to ProPro. This study suggested that PLAU Pro141Leu (rs2227564) is significantly associated with serum lipid levels in a Japanese population...
  40. ncbi request reprint Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions
    Chun xia Yang
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Asian Pac J Cancer Prev 6:256-62. 2005
    ..Interactions between ALDH2 and ADH2 need further clarification...
  41. doi request reprint Association between KLK3 rs2735839 G/A polymorphism and serum PSA levels in Japanese men
    Syunsuke Nobata
    Seirei Preventive Health Care Center, Hamamatsu, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Urol Int 89:39-44. 2012
    ..To clarify the association of kallikrein-related peptidase 3 (KLK3) rs2735839 G/A polymorphism with serum prostate-specific antigen (PSA) levels in Japanese men...
  42. ncbi request reprint Breast cancer risk and erythrocyte compositions of n-3 highly unsaturated fatty acids in Japanese
    Kiyonori Kuriki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Int J Cancer 121:377-85. 2007
    ....
  43. ncbi request reprint Lung cancer mortality and body mass index in a Japanese cohort: findings from the Japan Collaborative Cohort Study (JACC Study)
    Takaaki Kondo
    Department of Medical Technology, Nagoya University School of Health Sciences, 1 20 Daikominami 1 chome, Nagoya, Japan
    Cancer Causes Control 18:229-34. 2007
    ..To determine the relationship of body mass index (BMI) and BMI changes during adulthood to lung cancer mortality in a large-sized Japanese cohort...
  44. ncbi request reprint Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study
    Kazuko Nishio
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Causes Control 18:801-8. 2007
    ..To examine whether soy foods really have protective effects against breast cancer and how their influence on breast cancer is modified according to menopausal status, we conducted a population-based, prospective cohort study in Japan...
  45. ncbi request reprint Time spent walking or exercising and blood levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3): A large-scale cross-sectional study in the Japan Collaborative Cohort study
    Kenji Wakai
    Department of Preventive Medicine, Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Japan
    Asian Pac J Cancer Prev 10:23-7. 2009
    ..048). Our findings may partly explain the protective effects of physical activity against several sites of cancer...
  46. ncbi request reprint Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Oncology 68:454-61. 2005
    ..To elucidate whether leptin is involved in the etiology of female colorectal cancer...
  47. ncbi request reprint One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya 464 8681, Japan
    Carcinogenesis 26:2164-71. 2005
    ..In conclusion, we found consistently significant interactions between one-carbon metabolism-related polymorphisms and alcohol drinking...
  48. ncbi request reprint Gastric cancer risk and erythrocyte composition of docosahexaenoic acid with anti-inflammatory effects
    Kiyonori Kuriki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Epidemiol Biomarkers Prev 16:2406-15. 2007
    ..Further studies are needed to investigate mechanisms of action of DHA relevant to antitumor effects in the stomach...
  49. ncbi request reprint Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Obstet Gynaecol Res 31:452-8. 2005
    ..Here we investigated this relation using data from the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk, which was initiated in 1988...
  50. ncbi request reprint Attributable and absolute risk of lung cancer death by smoking status: findings from the Japan Collaborative Cohort Study
    Masahiko Ando
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Cancer 105:249-54. 2003
    ..For all current smokers, immediate cessation is encouraged because it offers the only realistic way to avoid a substantial increase in lung cancer mortality brought about by further continuation of smoking...
  51. ncbi request reprint Significant interaction between LRP2 rs2544390 in intron 1 and alcohol drinking for serum uric acid levels among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene 503:131-6. 2012
    ....
  52. ncbi request reprint A prospective study on the possible association between having children and colon cancer risk: findings from the JACC Study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Cancer Sci 95:243-7. 2004
    ..From these prospective data, having children may reduce risk of colon cancer among women, but not among men, suggesting that modifications of hormone profiles secondary to pregnancies may influence female colon cancer risk...
  53. ncbi request reprint Impact of menstrual and reproductive factors on breast cancer risk in Japan: results of the JACC study
    Koji Tamakoshi
    Department of Public Health Health Information Dynamics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550
    Cancer Sci 96:57-62. 2005
    ....
  54. doi request reprint No associations of Toll-like receptor 2 (TLR2) -196 to -174del polymorphism with the risk of Helicobacter pylori seropositivity, gastric atrophy, and gastric cancer in Japanese
    Asahi Hishida
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Showa Ku, Japan
    Gastric Cancer 13:251-7. 2010
    ..This study aimed to confirm the associations of the polymorphism with the risk of gastric cancer, as well as Helicobacter pylori seropositivity and the risk of gastric atrophy in Japanese...
  55. ncbi request reprint Effect of familial history and smoking on common cancer risks in Japan
    Takeshi Suzuki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Cancer 109:2116-23. 2007
    ..The authors further evaluated the effect modification by habitual smoking with adjustment for other confounding environmental factors...
  56. pmc Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study
    Kenji Wakai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Epidemiol 21:223-35. 2011
    ..To detect gene-environment interactions in the development of lifestyle-related diseases, and especially cancer, the Japan Multi-institutional Collaborative Cohort (J-MICC) Study was launched in 2005...
  57. ncbi request reprint Serum levels of polyunsaturated fatty acids and risk of colorectal cancer: a prospective study
    Masayo Kojima
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Am J Epidemiol 161:462-71. 2005
    ..No adverse effects of high serum levels of omega-6 polyunsaturated fatty acids on colorectal cancer risk were detected...
  58. ncbi request reprint Study profile on baseline survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Emi Morita
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Japan
    Nagoya J Med Sci 73:187-95. 2011
    ..Current drinkers included 74.9% (n=1099) of males and 45.9% (n=1699) of females. Lifestyle data and specimens were successfully collected to examine any associations among disease biomarkers, lifestyles, and genotypes...
  59. ncbi request reprint Cigarette smoking and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort study
    Yoshimitsu Niwa
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Obstet Gynaecol Res 31:144-51. 2005
    ..Here we investigated this relation using data from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk, initiated in 1988...
  60. pmc Obesity/weight gain and breast cancer risk: findings from the Japan collaborative cohort study for the evaluation of cancer risk
    Sadao Suzuki
    Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Epidemiol 23:139-45. 2013
    ....
  61. ncbi request reprint Association of obesity and diabetes with serum prostate-specific antigen levels in Japanese males
    Mariko Naito
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nagoya J Med Sci 74:285-92. 2012
    ..Our findings suggest that the pre-overweight men had increased PSA levels, and the diabetes was associated with a reduction of PSA levels in elderly...
  62. doi request reprint Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Mol Genet Metab 103:378-82. 2011
    ..This study was the first report to estimate the impact of SLC2A9 rs11722228 on SUA levels. Since the allele frequency of rs11722228 is similar among different ethnic groups, the impact remains to be examined in other ethnic groups...
  63. ncbi request reprint Impact of the alcohol-dehydrogenase (ADH) 1C and ADH1B polymorphisms on drinking behavior in nonalcoholic Japanese
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center, Nagoya, Japan
    Hum Mutat 28:506-10. 2007
    ..In conclusion, this study showed a significant impact of the ADH1C polymorphism on habitual drinking, regardless of the ADH1B/ALDH2 polymorphisms...
  64. pmc Significant association between Helicobacter pylori infection and serum C-reactive protein
    Yoshiko Ishida
    Department of Preventive Medicine, Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Med Sci 5:224-9. 2008
    ..Helicobacter pylori (H. pylori) infection in gastric mucosa may cause systemic inflammatory reaction. This study aimed to examine the association between the infection and serum high sensitivity C-reactive protein (hsCRP)...
  65. ncbi request reprint Serum insulin-like growth factors, insulin-like growth factor-binding protein-3, and risk of lung cancer death: a case-control study nested in the Japan Collaborative Cohort (JACC) Study
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8550, Japan
    Jpn J Cancer Res 93:1279-86. 2002
    ..A higher level of circulating IGFBP-3 and / or IGF-II may decrease lung cancer risk. Elevated serum IGF-I may increase the risk, but this could partly be attributable to latent tumors...
  66. doi request reprint Combined effect of miR-146a rs2910164 G/C polymorphism and Toll-like receptor 4 +3725 G/C polymorphism on the risk of severe gastric atrophy in Japanese
    Asahi Hishida
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, 466 8550, Japan
    Dig Dis Sci 56:1131-7. 2011
    ..A G/C polymorphism in miRNA-146a (rs2910164) was shown to be associated with the risk of hepatocellular carcinoma...
  67. doi request reprint Lung cancer risk and consumption of vegetables and fruit: an evaluation based on a systematic review of epidemiological evidence from Japan
    Kenji Wakai
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Jpn J Clin Oncol 41:693-708. 2011
    ..To re-assess this issue, we reviewed data from Japanese epidemiological studies...
  68. doi request reprint Cigarette smoking and esophageal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Isao Oze
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Jpn J Clin Oncol 42:63-73. 2012
    ..Therefore, we reviewed epidemiologic studies on the association between cigarette smoking and esophageal cancer among the Japanese population...
  69. ncbi request reprint Controls for monitoring the deterioration of stored blood samples in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study)
    Mariko Naito
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Nagoya J Med Sci 70:107-15. 2008
    ..The resulting findings will produce valuable information on the stability of the molecules, not only for the J-MICC Study, but also for other cohort studies...
  70. ncbi request reprint Psychological attitudes and risk of breast cancer in Japan: a prospective study
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya, 464 8681, Japan
    Cancer Causes Control 18:259-67. 2007
    ..To examine the association between psychological factors and the risk of breast cancer prospectively in a non-Western population...
  71. ncbi request reprint A past history of gastric ulcers and Helicobacter pylori infection increase the risk of gastric malignant lymphoma
    Takeshi Suzuki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Carcinogenesis 27:1391-7. 2006
    ..These results suggested the risk of gastric lymphoma increased by interaction between H. pylori infection and gastric ulcer history. Further studies are warranted...
  72. pmc Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population
    Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    BMC Med Genet 12:33. 2011
    ..This study examined serum uric acid (SUA) distribution according to SLC22A12 W258X genotype in a general Japanese population...
  73. ncbi request reprint An intervention study of smoking cessation with feedback on genetic cancer susceptibility in Japan
    Hidemi Ito
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Chikusaku Nagoya, Japan
    Prev Med 42:102-8. 2006
    ..To evaluate whether feedback of genetic information regarding an L-myc polymorphism, identified as impacting on tobacco-related cancer risk, has an influence on smoking cessation, an intervention study was conducted...
  74. ncbi request reprint Risk factors differ for non-small-cell lung cancers with and without EGFR mutation: assessment of smoking and sex by a case-control study in Japanese
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Cancer Sci 98:96-101. 2007
    ..In conclusion, our case-control study clearly demonstrated that the impacts of smoking and sex on the risk of EGFRmut NSCLC are different from those for EGFRwt NSCLC. Further epidemiological evaluation is warranted...
  75. ncbi request reprint Coffee consumption and the risk of endometrial cancer: Evidence from a case-control study of female hormone-related cancers in Japan
    Kaoru Hirose
    Department of Planning and Information, Aichi Prefectural Institute of Public Health, 7 6 Azanagare, Tsujimachi, Kita ku, Nagoya, Japan
    Cancer Sci 98:411-5. 2007
    ..Given the scarcity of studies of coffee intake and endometrial cancer and other hormone-dependent cancer risk, additional investigations are warranted...
  76. ncbi request reprint Decrease in risk of lung cancer death in Japanese men after smoking cessation by age at quitting: pooled analysis of three large-scale cohort studies
    Kenji Wakai
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
    Cancer Sci 98:584-9. 2007
    ....
  77. ncbi request reprint Modification of the effect of smoking on cholesterol in Japanese carriers of a PTPN11 polymorphism
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya 466 8550, Japan
    Mol Med Report 1:595-8. 2008
    ..039; HDL-C, p=0.020). These data suggest that cigarette smoking might alter the metabolism of cholesterol in Japanese PTPN11 AA genotype carriers...
  78. doi request reprint Cigarette smoking and pancreas cancer risk: an evaluation based on a systematic review of epidemiologic evidence in the Japanese population
    Keitaro Matsuo
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Jpn J Clin Oncol 41:1292-302. 2011
    ..Therefore, we reviewed epidemiologic studies on the association between cigarette smoking and pancreas cancer in the Japanese population...
  79. ncbi request reprint Smoking increases the treatment failure for Helicobacter pylori eradication
    Takeshi Suzuki
    Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
    Am J Med 119:217-24. 2006
    ..pylori) eradication is encountered in approximately 10-20% of patients, and many studies have pointed to a link with smoking. To investigate the effects of smoking on eradication outcome, we performed a meta-analysis...
  80. ncbi request reprint Risk factors for IgA nephropathy: a case-control study with incident cases in Japan
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Nephron 90:16-23. 2002
    ..Our previous study with prevalent cases suggested that some genetic, immunological and lifestyle-related factors increased the risk of immunoglobulin A nephropathy (IgAN). To confirm this hypothesis, we conducted another case-control study...
  81. ncbi request reprint Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity
    Chiyoe Kitagawa
    Department of Medicine, Division of Respiratory Diseases, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Pharmacogenet Genomics 15:35-41. 2005
    ..The determination of T-3279G and UGT1A1*28 genotypes might be clinically useful in predicting severe irinotecan toxicity in cancer patients...
  82. ncbi request reprint The association between tumour necrosis factor-alpha gene polymorphism and the susceptibility to rugal hyperplastic gastritis and gastric carcinoma
    Itaru Ohyama
    Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Eur J Gastroenterol Hepatol 16:693-700. 2004
    ..The aim of this study was to clarify the association of tumour necrosis factor-alpha (TNFA) gene polymorphism with susceptibility to hyper-rugosity. We also examined the association of TNFA polymorphism with gastric carcinoma...
  83. ncbi request reprint Duplex polymerase chain reaction with confronting two-pair primers (PCR-CTPP) for genotyping alcohol dehydrogenase beta subunit (ADH2) and aldehyde dehydrogenase 2 (ALDH2)
    Akiko Tamakoshi
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Alcohol Alcohol 38:407-10. 2003
    ....
  84. ncbi request reprint Lifestyle risk factors for intrahepatic stone: findings from a case-control study in an endemic area, Taiwan
    Masato Momiyama
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Gastroenterol Hepatol 23:1075-81. 2008
    ..To examine associations between lifestyle risk factors and intrahepatic stone (IHS), we conducted a case-control study in Taiwan, which has the highest incidence of IHS in the world...
  85. ncbi request reprint Association between decreased kidney function and endotoxin receptor CD14 C-159T polymorphism among Japanese health check-up examinees
    Rieko Okada
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Ren Fail 29:967-72. 2007
    ..This study was conducted to determine whether this polymorphism is associated with decreased kidney function...
  86. ncbi request reprint The JICA training course, community-based cancer prevention for the Asian and Pan-Pacific countries, fiscal year 2006 (epidemiological approach)
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Asian Pac J Cancer Prev 8:150-4. 2007
    ....
  87. pmc A review of food frequency questionnaires developed and validated in Japan
    Kenji Wakai
    Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    J Epidemiol 19:1-11. 2009
    ..Because dietary habits vary greatly, the FFQ must be tailored for use with specific populations. The usefulness of FFQs in Japan was assessed by reviewing questionnaires developed and validated in that country...
  88. ncbi request reprint The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults
    Hiroyasu Iso
    Public Health, Department of Social and Environmental Health, Osaka University and Osaka City University, Suita Shi, Osaka, Japan
    Ann Intern Med 144:554-62. 2006
    ..In western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear...
  89. ncbi request reprint Alcohol consumption and lung cancer mortality in Japanese men: results from Japan collaborative cohort (JACC) study
    Yoshikazu Nishino
    Division of Epidemiology, Miyagi Cancer Center Research Institute, Japan
    J Epidemiol 16:49-56. 2006
    ..The relationship between alcohol consumption and increased risk of lung cancer is controversial. This study was set up to investigate the association between alcohol consumption and death from lung cancer in a large Japanese cohort...
  90. ncbi request reprint Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study
    Yoshinori Ito
    Department of Public Health, Fujita Health University School of Health Sciences, Japan
    J Epidemiol 15:S140-9. 2005
    ..To examine the association by sex, we extended the follow-up and analyzed additional serum samples...
  91. ncbi request reprint Tobacco smoking and colorectal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population
    Tetsuya Mizoue
    Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashiku, Fukuoka 812 8582, Japan
    Jpn J Clin Oncol 36:25-39. 2006
    ..It is unclear whether tobacco smoking is related to colorectal cancer risk in Japan. We evaluated the association among the Japanese population based on a systematic review of epidemiologic evidence...
  92. ncbi request reprint Glucose intolerance and colorectal cancer risk in a nested case-control study among Japanese People
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S180-4. 2005
    ..Glucose intolerance may increase the risk of developing colorectal cancer...
  93. ncbi request reprint Dietary risk factors for inflammatory bowel disease: a multicenter case-control study in Japan
    Naomasa Sakamoto
    Department of Hygiene, Hyogo College of Medicine, Hyogo, Japan
    Inflamm Bowel Dis 11:154-63. 2005
    ....
  94. ncbi request reprint Dietary habits and risk of urothelial cancer incidence in the JACC Study
    Fumio Sakauchi
    Department of Public Health, Sapporo Medical University School of Medicine
    J Epidemiol 15:S190-5. 2005
    ..In the present study, the associations of dietary habits with the risk of urothelial cancer incidence were evaluated taking into consideration sex, age, and smoking habits...
  95. ncbi request reprint Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S196-202. 2005
    ....
  96. ncbi request reprint Association of serum carotenoid concentration and dietary habits among the JACC Study subjects
    Kotaro Ozasa
    Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan
    J Epidemiol 15:S220-7. 2005
    ....
  97. ncbi request reprint Associations of lifestyle factors with bone mineral density among male university students in Japan
    Isuzu Egami
    Department of Food and Nutrition, Nagoya Bunri College, Nagoya Japan
    J Epidemiol 13:48-55. 2003
    ..Single-life students had lower bone mineral density compared with those lived with families (p=0.044). Bone mineral density could be increased by modifying dietary habits in young men...
  98. ncbi request reprint Risk factors for kidney cancer in a Japanese population: findings from the JACC Study
    Masakazu Washio
    Department of Public Health, Sapporo Medical University School of Medicine, Hokkaido, Japan
    J Epidemiol 15:S203-11. 2005
    ..Although the incidence of kidney cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing...
  99. ncbi request reprint Alcohol consumption and mortality among middle-aged and elderly Japanese men and women
    Yingsong Lin
    Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan
    Ann Epidemiol 15:590-7. 2005
    ..We conducted a prospective cohort study to examine the association between alcohol intake and the risk of all-cause mortality among middle-aged and elderly Japanese men and women...
  100. ncbi request reprint Tobacco smoking and breast cancer risk: an evaluation based on a systematic review of epidemiological evidence among the Japanese population
    Chisato Nagata
    Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
    Jpn J Clin Oncol 36:387-94. 2006
    ..As tobacco smoking may be one of the few modifiable risk factors for breast cancer, we focused on the association between tobacco smoking and the risk of breast cancer in this review...
  101. ncbi request reprint Prevalence of chronic kidney disease (CKD) in the Japanese general population predicted by the MDRD equation modified by a Japanese coefficient
    Enyu Imai
    Department of Nephrology, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Clin Exp Nephrol 11:156-63. 2007
    ..However, to date, a nationwide epidemiological study has not been conducted yet to survey the CKD population...