Research Topics
Genomes and GenesSpecies | T TakezakiSummaryAffiliation: Aichi Cancer Center Country: Japan Publications
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Detail Information
Publications
Dietary protective and risk factors for esophageal and stomach cancers in a low-epidemic area for stomach cancer in Jiangsu Province, China: comparison with those in a high-epidemic areaT Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Chikusa ku, Nagoya 464 8681
Jpn J Cancer Res 92:1157-65. 2001....- hOGG1 Ser(326)Cys polymorphism and modification by environmental factors of stomach cancer risk in ChineseToshiro Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Int J Cancer 99:624-7. 2002..Our findings suggest that the hOGG1 Ser(326)Cys polymorphism may alter the impact of some environmental factors on stomach cancer development. For confirmation, an additional study with a larger number of subjects is now required... - The 5th JICA training course, community-based cancer prevention (epidemiological approach)Toshiro Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464-8681, Japan
Asian Pac J Cancer Prev 4:169-74. 2003 - Diet and lung cancer risk from a 14-year population-based prospective study in Japan: with special reference to fish consumptionToshiro Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
Nutr Cancer 45:160-7. 2003..We conclude that frequent fresh fish consumption, irrespective of the cooking method, may reduce the risk of lung cancer... - Effect of body size on breast-cancer risk among Japanese womenK Hirose
Division of Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan
Int J Cancer 80:349-55. 1999..These findings suggest that avoidance of marked weight gain during adult life, especially after natural menopause and/or after age 60, may reduce the risk of breast cancer... 
Dietary factors and lung cancer risk in Japanese: with special reference to fish consumption and adenocarcinomasT Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, 464 8681, Nagoya, Japan
Br J Cancer 84:1199-206. 2001..This study suggests cooked/raw fish consumption lowers the risk of adenocarcinoma of the lung in Japanese...- Possible risk reduction in esophageal cancer associated with MPO -463 A alleleK Matsuo
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Aichi, Japan
J Epidemiol 11:109-14. 2001..Although there are limitations for interpretation of this study because of prevalent case-control study and partial statistical significance, these results suggest that MPO -463 A allele reduce the risk of esophageal cancer... - Fish consumption and colorectal cancer: a case-reference study in JapanC-X Yang
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
Eur J Cancer Prev 12:109-15. 2003..Although there is some possible bias in epidemiological studies, the results suggest that frequent raw/cooked fish intake may decrease the risk while dried/salted fish, in contrast, may exert a detrimental effect... - Alcohol, smoking, and dietary status and susceptibility to malignant lymphoma in Japan: results of a hospital-based case-control study at Aichi Cancer CenterK Matsuo
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Aichi Cancer Center Hospital, Chikusa ku, Nagoya 464 86811
Jpn J Cancer Res 92:1011-7. 2001..From the previous study on genetic background for ML [Matsuo et al., Blood, 97, 3205 - 3209 (2001)], genetic variation combined with limited environmental factors should be targeted in future studies... - Smoking habit and interleukin lB C-31T polymorphismN Hamajima
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
J Epidemiol 11:120-5. 2001..42-1.61) for the examinees. Although not significant for the examinees, the observed associations suggest that this polymorphism may influence smoking behavior through an inflammatory response of the respiratory tract to cigarette smoke... - Association of family history and other risk factors with breast cancer risk among Japanese premenopausal and postmenopausal womenK Hirose
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Japan
Cancer Causes Control 12:349-58. 2001..They imply that avoidance of obesity after menopause may reduce the risk of breast cancer, regardless of FH... - Association of polymorphisms in the beta-2 and beta-3 adrenoceptor genes with risk of colorectal cancer in JapaneseT Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Int J Clin Oncol 6:117-22. 2001..To examine links between polymorphisms in these genes and the risk of colorectal cancer in Japanese, we conducted the present hospital-based case-referent study... - Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancerK Matsuo
Division of Epidemiology and Prevention, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya, Aichi 464 8681, Japan
Carcinogenesis 22:913-6. 2001..Taking the observed high risk of esophageal cancer in association with the ALDH2 Lys487 allele into consideration, reducing alcohol intake may be most protective among Lys487 allele carriers of this polymorphism... - Insulin, insulin-like growth factor-I and breast cancer risk in Japanese womenKaoru Hirose
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
Asian Pac J Cancer Prev 4:239-46. 2003..Additional studies are needed to clarify the role of glucose metabolism pathways in breast cancer development and interaction of IGF systems... - Foods and beverages in relation to urothelial cancer: case-control study in JapanKenji Wakai
Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan
Int J Urol 11:11-9. 2004..The roles of several foods and beverages in the development of bladder cancer remain unclear... - Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smokingChang Ming Gao
Department of Epidemiology, Jiangsu Province Institute of Cancer Research, Nanjing, China
Asian Pac J Cancer Prev 5:133-8. 2004.... - Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancerKazuya Shinmura
First Department of Pathology, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu, Shizuoka 431 3192, Japan
Carcinogenesis 25:2311-7. 2004..These results suggest that low NEIL1 activities arising from mutations and reduced expression may be involved in the pathogenesis in a subset of gastric cancers... - Development of a semi-quantitative food frequency questionnaire to determine variation in nutrient intakes between urban and rural areas of Chongqing, ChinaZi-Yuan Zhou
Department of Hygiene Toxicology, Faculty of Preventive Medicine, Third Military Medical University, Chongqing, China
Asia Pac J Clin Nutr 13:273-83. 2004..We were able to develop a data-based SQFFQ that can estimate nutrient intake of both urban and rural populations, with suitable coverage rates. Further reliability and reproducibility tests are now needed to assess its applicability... - Comparison of lifestyle risk factors by family history for gastric, breast, lung and colorectal cancerXin En Huang
Department of Chemotherapy, Jiangsu Cancer Hospital and Research Institute, Nanjing 210009, China
Asian Pac J Cancer Prev 5:419-27. 2004..Habitual smoking increased, while frequent physical exercise and raw vegetables intake decreased cancer risk, regardless of the CFH status... - Lung cancer death rates by smoking status: comparison of the Three-Prefecture Cohort study in Japan to the Cancer Prevention Study II in the USATomomi Marugame
Statistics and Cancer Control Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Cancer Sci 96:120-6. 2005..34 [95%CI 0.27-0.43]). These findings might explain why Japanese risks of lung cancer are lower than those observed in Western countries... - Charcoal cigarette filters and lung cancer risk in Aichi Prefecture, JapanJoshua E Muscat
Department of Health Evaluation Sciences, Penn State Cancer Institute, Division of Population Sciences, Penn State College of Medicine, Hershey, PA 17033, USA
Cancer Sci 96:283-7. 2005..As the detection of a modest benefit or risk (e.g. 10-20%) that can have significant public health impact requires large samples, the findings should be confirmed or refuted in larger studies... - The KOJACH food frequency questionnaire for Chaoshan, China: development and descriptionKe Li
Department of Preventive Medicine, Shantou Medical University, Shantou 515041, Guangdong Province, China
Asia Pac J Clin Nutr 15:153-60. 2006..For adoption of the area-specific SQFFQ, Validity and reproducibility tests are now planned to determine how the combined SQFFQ performs in actual assessment of disease risk and benefit... - Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and colorectal cancer risk in JapaneseKiyonori Kuriki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Cancer Sci 97:1226-35. 2006.... - CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinkingChang Ming Gao
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
World J Gastroenterol 13:5725-30. 2007..To investigate associations between the Rsa I polymorphism of CYP2E1 and risk of colorectal cancer... - Dietary factors protective against breast cancer in Japanese premenopausal and postmenopausal womenKaoru Hirose
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
Int J Cancer 107:276-82. 2003..61, 95% CI 0.41-0.91). Thus, traditional Japanese dietary factors may protect against breast cancer development, especially among postmenopausal women... - A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lungHidemi Ito
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
J Epidemiol 12:258-65. 2002..This study supported the first study by Sugimura et al (Cancer Epidemiol Biomarkers Prev, 1999; 8: 669-674), that the association of OGG1 Ser326Cys polymorphism was limited for the risk of lung adenocarcinoma... - Height, weight, menstrual and reproductive factors and risk of gastric cancer among Japanese postmenopausal women: analysis by subsite and histologic subtypeManami Inoue
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
Int J Cancer 97:833-8. 2002..From these results, however, it appears that height, weight, menstrual and reproductive factors have less impact on gastric cancer than environmental factors such as smoking and dietary habits or family history of gastric cancer... - A49T, V89L and TA repeat polymorphisms of steroid 5alpha-reductase type II and breast cancer risk in Japanese womenChunxia Yang
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Breast Cancer Res 4:R8. 2002..To test the hypothesis that these three polymorphisms are associated with risk of breast cancer, a case-control study was conducted with patients of Aichi Cancer Center Hospital... - [Risk and protective factors in lung cancer other than the smoking habit]Toshiro Takezaki
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute
Nippon Rinsho 60:42-5. 2002 - Interaction between cytochrome P-450 2E1 polymorphisms and environmental factors with risk of esophageal and stomach cancers in ChineseChangming Gao
Division of Epidemiology, Cancer Research Institute of Jiangsu Province, Nanjing 210009, China
Cancer Epidemiol Biomarkers Prev 11:29-34. 2002..These results suggest that gene-environment interactions between the CYP2E1 polymorphism and smoking may have the potential to alter the susceptibility for cancer development in the stomach... - Helicobacter pylori seropositivity and IL-1B C-31T polymorphism among Japanese BraziliansMiyuki Uno
Department of Clinical Laboratory, Aichi Cancer Center, Kanokoden, Chikusa ku, Nagoya, Japan
Int J Mol Med 10:321-6. 2002..8%, and had no association with the HP seropositivity. The observed association between HP+ and IL-1B -31TT indicated that the genetic trait also influences the susceptibility to HP for Japanese in Brazil... - Glutathione-S-transferases M1 (GSTM1) and GSTT1 genotype, smoking, consumption of alcohol and tea and risk of esophageal and stomach cancers: a case-control study of a high-incidence area in Jiangsu Province, ChinaChang Ming Gao
Division of Epidemiology, Jiangsu Province Institute of Cancer Research, 42 Baiziting, Nanjing 210009, China
Cancer Lett 188:95-102. 2002..These findings suggest the GSTM1 polymorphism is involved in the susceptibility to esophageal cancer development, and tea consumption reduces the risk of esophageal and stomach cancers... - Dietary factors and the risk of gastric cancer among Japanese women: a comparison between the differentiated and non-differentiated subtypesLucy Sayuri Ito
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
Ann Epidemiol 13:24-31. 2003.... - Geographical variation in nutrient intake between urban and rural areas of Jiangsu province, China and development of a semi-quantitative food frequency questionnaire for middle-aged inhabitantsYing-Ming Wang
Department of Nutrition and Food Science, Nanjing Medical University
J Epidemiol 13:80-9. 2003..Further validity and reproducibility tests are now needed to assess their appropriateness for usage... - Physical exercise reduces risk of breast cancer in Japanese womenKaoru Hirose
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681
Cancer Sci 94:193-9. 2003..This study provides evidence that physical exercise, especially exercise twice a week or more, reduces the risk of breast cancer among Japanese women... - Epidemiology of pancreatic cancer in Japan: a nested case-control study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC)Manami Inoue
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
Int J Epidemiol 32:257-62. 2003.... - Aldehyde dehydrogenase 2 (ALDH2) genotype affects rectal cancer susceptibility due to alcohol consumptionKeitaro Matsuo
Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
J Epidemiol 12:70-6. 2002..The alcohol related enzyme encoding gene ALDH2 has polymorphism Glu487Lys, and 487Lys allele is closely linked with phenotypic loss of enzyme activity... - Reproducibility of a semi-quantitative food frequency questionnaire in Chaoshan area, ChinaKe Li
Department of Preventive Medicine, Shantou Medical University, Shantou 515041, Guangdong Province, China
Asian Pac J Cancer Prev 6:521-6. 2005..To examine reproducibility of assessed intake of foods and nutrients according to a semi-quantitative food frequency questionnaire (SQFFQ) in adult doctors and nurses residing in Chaoshan area of China... - Duplex polymerase chain reaction with confronting two-pair primers (PCR-CTPP) for genotyping alcohol dehydrogenase beta subunit (ADH2) and aldehyde dehydrogenase 2 (ALDH2)Akiko Tamakoshi
Department of Preventive Medicine Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Alcohol Alcohol 38:407-10. 2003.... - Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC reviewStefania Boccia
Institute of Hygiene, Universita Cattolica del Sacro Cuore, Rome, Italy
Am J Epidemiol 167:505-16. 2008..05, 95% CI: 1.13, 3.72) versus high (OR = 0.95, 95% CI: 0.54, 1.67) folate levels. Overall, these findings support the hypothesis that folate plays a role in gastric carcinogenesis...