Research Topics
| Yasuhiro ShimizuSummaryAffiliation: Aichi Cancer Center Country: Japan Publications
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Detail Information
Publications
Small carcinoma of the pancreas is curable: new computed tomography finding, pathological study and postoperative results from a single instituteYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
J Gastroenterol Hepatol 20:1591-4. 2005....- Implantation metastasis along the percutaneous transhepatic biliary drainage sinus tractYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
Hepatogastroenterology 51:365-7. 2004..If left in place, careful follow-up and awareness of this mode of tumor recurrence may lead to a timely resection, with preservation of a good quality of life and long-term survival... - Predicting pleural effusion and ascites following extended hepatectomy in the non-cirrhotic liverYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
J Gastroenterol Hepatol 22:837-40. 2007..In this study we investigated the risk factors for pleural effusion and ascites following extended hepatectomy... - Treatment strategy for synchronous metastases of colorectal cancer: is hepatic resection after an observation interval appropriate?Yasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
Langenbecks Arch Surg 392:535-8. 2007..Our treatment policy has been to conduct hepatic resection for the metastases at an interval of 3 months after colorectal resection. We examined the appropriateness of interval hepatic resection for synchronous hepatic metastasis... - Late complication in patients undergoing pancreatic resection with intraoperative radiation therapy: gastrointestinal bleeding with occlusion of the portal systemYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya 464, Japan
J Gastroenterol Hepatol 20:1235-40. 2005..The purpose of the present paper was to review gastrointestinal (GI) bleeding occurring with occlusion of the portal system (PVs) as a complication of IORT in patients surviving long term without recurrence... 
A nomogram for predicting the probability of carcinoma in patients with intraductal papillary-mucinous neoplasmYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
World J Surg 34:2932-8. 2010..The objective of the present study was to use clinical and laboratory data to develop a model for predicting the presence of carcinoma in patients with intraductal papillary mucinous neoplasm (IPMN)...- Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic fociYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Kanokoden 1 1, Chikusa ku, Nagoya, 464 8681, Japan
Langenbecks Arch Surg 393:181-4. 2008..Our treatment policy has been to reevaluate the metastases at an interval of 3 months after colorectal resection and determine treatment strategy. We examined the validity of observation interval for synchronous hepatic metastases... - Adequate length of the surgical distal resection margin in rectal cancer: from the viewpoint of pathological findingsKoji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa Nagoya, Aichi, 464 8681 Japan
Am J Surg 204:474-80. 2012..Previous studies have not identified how to determine the optimal distal margin in rectal cancer based on histopathological diagnosis. We examined the surgical distal resection margin from a histopathological viewpoint... - Clinical impact of K-ras mutation analysis in EUS-guided FNA specimens from pancreatic massesTakeshi Ogura
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
Gastrointest Endosc 75:769-74. 2012..EUS-guided FNA (EUS-FNA) is considered optimal for differentially diagnosing pancreatic masses. However, the sensitivity of EUS-FNA ranges from 65% to 95%, respectively, which requires improvement... - Possible oncogenesis of mucinous cystic tumors of the pancreas lacking ovarian-like stromaYasuhiro Shimizu
Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, Japan
Pancreatology 2:413-20. 2002..MCTs with ovarian-like stroma (MCTs-OLS+; n = 6) and those lacking ovarian-like stroma (MCTs-OLS-; n = 4) were compared to elucidate the oncogenesis of MCT without OLS... - Prolonged survival of patients with metastatic colorectal cancer following first-line oxaliplatin-based chemotherapy with molecular targeting agents and curative surgeryKohei Shitara
Department of Clinical Oncology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
Oncology 81:167-74. 2011..The ability of molecular targeting agents to improve overall survival (OS) in metastatic colorectal cancer (MCRC) patients who underwent oxaliplatin-based chemotherapy remains controversial... - Analysis of lymph node metastatic pattern according to the depth of in-growth in the muscularis propria in T2 rectal cancer for lateral lymph node dissectionKoji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
Dig Surg 28:352-9. 2011..The biological behavior of rectal cancers that invade the muscularis propria (pT2) has not been well studied. We retrospectively studied the pattern of lymph node metastases in patients with T2 rectal cancer... - Quantitative detection of disseminated cancer cells in the greater omentum of gastric carcinoma patients with real-time RT-PCR: a comparison with peritoneal lavage cytologyYasuhiro Kodera
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
Gastric Cancer 5:69-76. 2002..CONCLUSION: Quantitative RT-PCR of peritoneal washes remains the first choice as a tool to sensitively predict intraperitoneal recurrence in gastric carcinoma patients... - Acute portal vein thrombosis after EUS-guided FNA of pancreatic cancer: case reportKakuya Matsumoto
Department of Gastroenterology, Aichi Cancer Center, Nagoya, Japan
Gastrointest Endosc 57:269-71. 2003 - Current concept of endoscopic ultrasound-guided fine needle aspiration for pancreatic cancerNobumasa Mizuno
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan nobumasa aichi cc jp
Pancreatology 11:40-6. 2011..This review highlights the diagnostic potential of EUS-FNA, as well as its current indications and contraindications, complications, and techniques... - Diagnostic approach to pancreatic tumors with the specimens of endoscopic ultrasound-guided fine needle aspirationWaki Hosoda
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan
Pathol Int 60:358-64. 2010..The usefulness of these markers was confirmed using 13 additional pancreatic tumors, prospectively. Although minimal in selection, these markers are helpful in making diagnosis from EUS-FNA specimens of the major pancreatic tumors... - Prospective clinical study of EUS-guided choledochoduodenostomy for malignant lower biliary tract obstructionKazuo Hara
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
Am J Gastroenterol 106:1239-45. 2011..However, prospective studies of EUS-CDS have not yet been performed. We conducted a prospective study to evaluate the safety, feasibility, and efficacy of EUS-CDS in patients with malignant lower biliary tract obstruction... - Survival after curative resection for mucinous adenocarcinoma of the colorectumYukihide Kanemitsu
Department of Gastroenterological Surgery, The Aichi Cancer Center, Kanokoden, Nagoya, Japan
Dis Colon Rectum 46:160-7. 2003.... - Interventional endoscopic ultrasonographyKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
J Gastroenterol Hepatol 24:509-19. 2009..In this review, we particularly focus on the present and future roles of interventional EUS, including EUS-FNA and therapeutic EUS... - Clinicopathological study of poorly differentiated colorectal adenocarcinomas: comparison between solid-type and non-solid-type adenocarcinomasKoji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa Nagoya, Aichi 464 8681, Japan
Anticancer Res 31:3463-7. 2011..We aimed to clarify the clinicopathological features of poorly differentiated colorectal adenocarcinomas and to define two subtypes of these adenocarcinomas... - Diagnosis of autoimmune pancreatitis using endoscopic ultrasonographyNoriyuki Hoki
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
J Gastroenterol 44:154-9. 2009..These criteria require distinguishing AIP from neoplastic lesions. However, this can be difficult, and patients often undergo surgery on the basis of suspected pancreatic cancer (PC)... - Is "depth of submucosal invasion > or = 1,000 microm" an important predictive factor for lymph node metastases in early invasive colorectal cancer (pT1)?Koji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa, Nagoya, Aichi 464 8681, Japan
Hepatogastroenterology 57:1123-7. 2010.... - Rare pancreatic neoplasms: the utility of endoscopic ultrasound-guided fine-needle aspiration-a large single center studyHiroshi Imaoka
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden Chikusa ku, Nagoya 464 8681, Japan
J Gastroenterol 44:146-53. 2009..We describe the performance and pitfalls of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for diagnosis of these rare pancreatic tumors and their characteristic cytopathological features... - Treatment and risk factors for recurrence after curative resection of gastrointestinal stromal tumors of the stomachYoshinari Mochizuki
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1-1, Kanokoden, Chikusa-ku, 464-8681 Nagoya, Japan
World J Surg 28:870-5. 2004..0051). In conclusion, surgical resection may be indicated whenever a recurrent GIST is considered resectable. A high MIB-1 PI was identified as an independent indicator of risk for recurrent disease following curative surgery... - [Surgical treatment for colorectal liver metastases--results of multi-institute study for effects of radical hepatectomy]Kenzo Yasui
Department of Gastroenterological Surgery, Aichi Cancer Center, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan
Gan To Kagaku Ryoho 31:690-4. 2004..2% to 11.9% in each institute. This suggests that there could be a difference in diagnostic accuracy, surgical indication or timing of surgery for synchronous liver metastases in each institute... - Endoscopic diagnosis and staging of mucinous cystic neoplasms and intraductal papillary-mucinous tumorsKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-0021, Japan
J Hepatobiliary Pancreat Surg 10:142-6. 2003..They are effective for differential diagnosis, for assessing the degree of malignancy, and for deciding upon an appropriate treatment in patients with IPMTs... - Endoscopic ultrasound-guided choledochoduodenostomy for malignant lower biliary tract obstructionKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Gastrointest Endosc Clin N Am 22:259-69, ix. 2012..In addition, the stents placed by EUS-CDS had a longer patency than transpapillary biliary stents... 
Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasisHai xing Ju
Division of Molecular Oncology, Aichi Cancer Center Research Institute, Nagoya, Japan
Am J Pathol 178:1835-46. 2011..In addition, most methylation status in stage IV CRCs seems to be established before metastasis...- Pathology studies of combined radical resection of seminal vesicle in the treatment of rectal cancerKoji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
Int Surg 96:51-5. 2011..Combined radical resection of the seminal vesicle in patients with rectal cancer ensures that the distance of the circumferential resection margin is sufficient to inhibit local recurrence... - Interventional endoscopic ultrasonography for pancreatic cancerKazuo Hara
Kazuo Hara, Kenji Yamao, Nobumasa Mizuno, Susumu Hijioka, Akira Sawaki, Masahiro Tajika, Hiroki Kawai, Shinya Kondo, Yasumasa Niwa, Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya 464 8681, Japan
World J Clin Oncol 2:108-14. 2011..This review focuses on interventional EUS, including EUS-FNA and therapeutic EUS for pancreatic cancer... - Quantitative detection of disseminated free cancer cells in peritoneal washes with real-time reverse transcriptase-polymerase chain reaction: a sensitive predictor of outcome for patients with gastric carcinomaYasuhiro Kodera
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya Aichi, Japan
Ann Surg 235:499-506. 2002..To evaluate the feasibility of real-time reverse transcriptase-polymerase chain reaction (RT-PCR) detection of free cancer cells in the peritoneal washes as a prognostic indicator for patients with gastric carcinoma... - Diagnostic yield of endoscopic retrograde cholangiography and of EUS-guided fine needle aspiration sampling in gallbladder carcinomasSusumu Hijioka
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden, Chikusa ku, Nagoya, Aichi, 464 8681, Japan
J Hepatobiliary Pancreat Sci 19:650-5. 2012..We compared the diagnostic value and safety of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) with endoscopic retrograde cholangiography (ERC) in patients with suspected GBC... - Pancreaticobiliary maljunction in monozygotic twins--a case reportKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
Hepatogastroenterology 51:675-8. 2004..This case is not only of academic interest for familial occurrence, but also of clinical interest in the early detection of pancreaticobiliary maljunction... - EUS-Guided Biliary DrainageKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
Gut Liver 4:S67-75. 2010.... - Effect of a tyrosine kinase inhibitor STI571 in a patient with hepatic metastases from a duodenal gastrointestinal stromal tumorAkira Sawaki
Department of Gastroenterology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-0021, Japan
J Gastroenterol 38:690-4. 2003..This case report describes a highly effective use of STI571 in a 54-year-old woman with multiple liver metastases from a GIST originating in the duodenum... - A randomized phase II/III trial comparing hepatectomy followed by mFOLFOX6 with hepatectomy alone as treatment for liver metastasis from colorectal cancer: Japan Clinical Oncology Group Study JCOG0603Yukihide Kanemitsu
Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Jpn J Clin Oncol 39:406-9. 2009..The primary endpoint is treatment compliance at nine courses of mFOLFOX6 regimen in Phase II and disease-free survival in Phase III. The secondary endpoints are overall survival, incidence of adverse events and patterns of recurrence... - Tumor necrosis in patients with TNM stage IV colorectal cancer without residual disease (R0 Status) is associated with a poor prognosisKoji Komori
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1 1, Kanokoden, Chikusa, Nagoya, Aichi 464 8681, Japan
Anticancer Res 33:1099-105. 2013..To examine the usefulness of the histopathological finding of tumor necrosis for stratifying TNM stage IV colorectal cancer in R0 status... - Can EUS-guided FNA distinguish between gallbladder cancer and xanthogranulomatous cholecystitis?Susumu Hijioka
Department of Gastroenterology, Aichi Cancer Center Hospital, Chikusa ku, Nagoya, Japan
Gastrointest Endosc 72:622-7. 2010..EUS-guided FNA (EUS-FNA) is a useful modality for sampling various targets, but its applicability to gallbladder (GB) mass lesions is limited... - Usefulness of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for undiagnosed intra-abdominal lymphadenopathyOsamu Nakahara
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
J Gastroenterol 44:562-7. 2009..The aim of this study was to evaluate the yield of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in patients with undiagnosed intra-abdominal lymphadenopathy... - Carcinoma of the hepatic hilus developing 21 years after biliary diversion for choledochal cyst: a case reportMasahiko Koike
Department of Gastrointestinal Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
Hepatogastroenterology 49:1216-20. 2002..She underwent a curative resection of the tumor. Biliary tract carcinoma may be a late postoperative complications of choledochal cysts. Long-term follow-up of the patient is necessary after the primary operation... - Pancreatic endocrine neoplasm can mimic serous cystadenomaHiroshi Imaoka
Department of Gastroenterology, Aichi Cancer Center Hospital, 1 1 Kanokoden Chikusa ku, Nagoya, Japan
Int J Gastrointest Cancer 35:217-20. 2005..This case suggests that it is very difficult to distinguish PENs from SCAs based solely on imaging methods. EUS-FNAB is essential for determining the appropriate therapeutic strategy, as it provides the histopathological diagnosis... - Surgical treatment for metastatic malignancies. Anatomical resection of liver metastasis: indications and outcomesKenzo Yasui
Department of Gastroenterological Surgery, Aichi Cancer Center, 1 1 Kanokoden, Nagoya 464 8681, Japan
Int J Clin Oncol 10:86-96. 2005..Anatomical resection provides a higher probability of coresecting microscopic invasions that are predictable but undetectable, and can be recommended as a standard procedure for locally advanced metastatic liver cancer... - Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB): past, present, and futureKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Nagoya 464-8681, Japan
J Gastroenterol 40:1013-23. 2005.... - [ case of arteriovenous malformation of the pancreas with Osler-Weber-Rendu disease]Toshihiro Muto
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital
Nihon Shokakibyo Gakkai Zasshi 105:719-24. 2008..This is the first reported case of arteriovenous malformation with Osler-Weber-Rendu disease in Japan... - Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomasWentao Gao
Division of Molecular Oncology, Aichi Cancer Center Research Institute, 1 1 Kanokoden, Chikusa ku, Nagoya 464 8681, Japan
Carcinogenesis 29:1901-10. 2008..Our global epigenome analysis reveals distinct patterns of methylation that are probably to represent different pathophysiologic processes in HCCs... - BCL10 as a useful marker for pancreatic acinar cell carcinoma, especially using endoscopic ultrasound cytology specimensWaki Hosoda
Department of Pathology, Aichi Cancer Center Hospital, Nagoya, Japan
Pathol Int 63:176-82. 2013..Therefore, we suggested that BCL10 expression is a useful marker for acinar cell differentiation, particularly in the diagnosis of EUS-FNA specimens... - Efficacy of peroral pancreatoscopy in the diagnosis of pancreatic diseasesKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan
Gastrointest Endosc 57:205-9. 2003..Peroral pancreatoscopy with a thin fiberscope can provide a definitive diagnosis of intraductal papillary-mucinous tumor including the degree of malignancy... - Cdx2 expression in pancreatic tumors: Relationship with prognosis of invasive ductal carcinomasKakuya Matsumoto
Division of Oncological Pathology, Aichi Cancer Center Research Institute, Nagoya 464 8681, Japan
Oncol Rep 12:1239-43. 2004..015). In conclusion, our data suggest that Cdx2 might be necessary for intestinal phenotypic expression even in pancreatic tumor cells. In addition, Cdx2 expression in IDCs may be a novel prognostic marker for patient survival... - [A case report of recurrent gastric cancer in which combination chemotherapy with paclitaxel and 5-fluorouracil made for successful biliary stenting and improvement in QOL]Shinji Ohtani
Dept. of Surgery, Hiroshima Teishin Hospital
Gan To Kagaku Ryoho 32:81-4. 2005..Furthermore, billiary stenting was performed and a PTCD tube could be removed after 4 courses. No serious adverse effect was observed, and the patient maintained good QOL through this treatment... - Incidence and consequence of falls in inpatient rehabilitation of stroke patientsToru Suzuki
Department of Rehabilitation Medicine, Nanakuri Sanatorium, Fujita Health University, 424 1 Mukoubiro, Ohdori, Hisai, Mie, Japan
Exp Aging Res 31:457-69. 2005..Those with cognitive subscore on the FIM lower than 29 were prone to fall. Also, deteriorated motor and cognitive functions were associated with a high risk of falls... - Pseudomyxoma peritonei caused by acute pancreatitis in intraductal papillary mucinous carcinoma of the pancreasHiroshi Imaoka
Pancreas 32:223-4. 2006 - [A case report of advanced gastric cancer with carcinomatous ascites successfully treated by outpatient chemotherapy]Shinji Ohtani
Dept of Surgery, Hiroshima Teishin Hospital
Gan To Kagaku Ryoho 34:85-7. 2007..Tumor marker decreased remarkably, and CT revealed reduction of peritoneal dissemination. These regimens seem to be effective in ambulant patients with advanced gastric cancer with peritoneal dissemination and carcinomatous ascites... - Risk factors for pancreatic cancer and early diagnosis of pancreatic cancerKenji Yamao
Department of Gastroenterology, Aichi Cancer Center Hospital
Nippon Shokakibyo Gakkai Zasshi 105:8-16. 2008 - [A case of anaplastic ductal carcinoma (giant cell carcinoma of osteoclastoid type) with portal vein and main pancreatic ductal invasion]Toshifumi Isaka
Department of Gastroenterology, Aichi Cancer Center Hospital
Nippon Shokakibyo Gakkai Zasshi 102:736-40. 2005