Makio Mogi

Summary

Affiliation: Aichi-Gakuin University
Country: Japan

Publications

  1. ncbi request reprint p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya 464 8650, Japan
    Neurosci Lett 414:94-7. 2007
  2. ncbi request reprint Expression of cathepsin-K in gingival crevicular fluid of patients with periodontitis
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 52:894-8. 2007
  3. doi request reprint Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Aichi, Japan
    Biochem Biophys Res Commun 384:82-6. 2009
  4. doi request reprint Down-regulation of NF-kappaB led to up-regulation of NGF production in mouse osteoblasts
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 31:92-101. 2010
  5. ncbi request reprint Dual roles for NF-kappaB activation in osteoblastic cells by serum deprivation: osteoblastic apoptosis and cell-cycle arrest
    M Mogi
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Bone 35:507-16. 2004
  6. doi request reprint ELISA for RANKL-OPG complex in mouse sera
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 31:103-10. 2010
  7. ncbi request reprint Activation of caspases is required for osteoblastic differentiation
    Makio Mogi
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    J Biol Chem 278:47477-82. 2003
  8. ncbi request reprint Cytokine-induced nitric-oxide-dependent apoptosis in mouse osteoblastic cells: involvement of p38MAP kinase
    Masatoshi Kuzushima
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 51:1048-53. 2006
  9. ncbi request reprint Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells
    Nobuaki Ozeki
    Department of Endodontics, School of Dentistry, Aichi Gakuin University, Nagoya 464 8651, Japan
    Arch Oral Biol 47:511-7. 2002
  10. ncbi request reprint Involvement of p38MAP kinase in bone morphogenetic protein-4-induced osteoprotegerin in mouse bone-marrow-derived stromal cells
    Michiko Tazoe
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 48:615-9. 2003

Collaborators

Detail Information

Publications16

  1. ncbi request reprint p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya 464 8650, Japan
    Neurosci Lett 414:94-7. 2007
    ....
  2. ncbi request reprint Expression of cathepsin-K in gingival crevicular fluid of patients with periodontitis
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 52:894-8. 2007
    ..005 versus control subjects). Also, there was a positive correlation between cathepsin-K and RANKL levels (r=0.726), suggesting that both of them contribute to osteoclastic bone destruction in periodontal disease...
  3. doi request reprint Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Aichi, Japan
    Biochem Biophys Res Commun 384:82-6. 2009
    ..Thus, suitable suppression of mTOR phosphorylation is a necessary requirement for OPG production in bone marrow stromal cells...
  4. doi request reprint Down-regulation of NF-kappaB led to up-regulation of NGF production in mouse osteoblasts
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 31:92-101. 2010
    ..These findings demonstrate that the suitable suppression of NF-kappaB nuclear translocation induced NGF production in non-neuronal osteoblastic cells...
  5. ncbi request reprint Dual roles for NF-kappaB activation in osteoblastic cells by serum deprivation: osteoblastic apoptosis and cell-cycle arrest
    M Mogi
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Bone 35:507-16. 2004
    ..Taken together, our present results identify a novel role for NF-kappaB in cell-cycle and apoptosis regulation and underscore the significance of each independent signal cascade in serum-deprived osteoblastic cells...
  6. doi request reprint ELISA for RANKL-OPG complex in mouse sera
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 31:103-10. 2010
    ..Employing this assay system, we demonstrated that the RANKL-OPG complex was constitutively present in the serum of OPG+/- mice, but not in that of OPG-/- or wild-type C57BL/6 J mice...
  7. ncbi request reprint Activation of caspases is required for osteoblastic differentiation
    Makio Mogi
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    J Biol Chem 278:47477-82. 2003
    ..Taken together, these results confirm a unique and unanticipated role for the caspase-mediated signal cascade in the differentiation of osteoblasts...
  8. ncbi request reprint Cytokine-induced nitric-oxide-dependent apoptosis in mouse osteoblastic cells: involvement of p38MAP kinase
    Masatoshi Kuzushima
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 51:1048-53. 2006
    ..These results demonstrate that this cytokine-induced apoptosis in mouse osteoblastic cells was mediated by a p38MAP-kinase-dependent iNOS system...
  9. ncbi request reprint Differential expression of the Fas-Fas ligand system on cytokine-induced apoptotic cell death in mouse osteoblastic cells
    Nobuaki Ozeki
    Department of Endodontics, School of Dentistry, Aichi Gakuin University, Nagoya 464 8651, Japan
    Arch Oral Biol 47:511-7. 2002
    ....
  10. ncbi request reprint Involvement of p38MAP kinase in bone morphogenetic protein-4-induced osteoprotegerin in mouse bone-marrow-derived stromal cells
    Michiko Tazoe
    Department of Pharmacology, School of Dentistry, Aichi Gakuin University, Nagoya 464 8650, Japan
    Arch Oral Biol 48:615-9. 2003
    ..These results clearly suggest that activation of the p38MAP kinase pathway is necessary for BMP-4-induced OPG induction in ST2 cells...
  11. doi request reprint The presence of RANKL-OPG complex in human osteosarcoma U2OS
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 34:356-64. 2013
    ....
  12. doi request reprint The presence of TRAIL-OPG complex in human osteosarcoma and human salivary gland adenocarcinoma
    Makio Mogi
    Department of Medicinal Biochemistry, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    J Immunoassay Immunochem 32:70-8. 2011
    ..Employing this assay system, we demonstrated that the TRAIL-OPG complex was constitutively present in the human osteosarcoma cell lines, HOS, MG-63, and human salivary gland adenocarcinoma cell line, HSG...
  13. ncbi request reprint IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL
    Shigeru Kotake
    Institute of Rheumatology, Tokyo Women s Medical University, Tokyo, Japan
    Eur J Immunol 35:3353-63. 2005
    ..Contrary to our hypothesis, IFN-gamma(+) human T cells induced osteoclastogenesis through the expression of RANKL, suggesting that Th1 cells play a direct role in bone resorption in Th1 dominant diseases such as RA...
  14. ncbi request reprint Muramyl dipeptide enhances osteoclast formation induced by lipopolysaccharide, IL-1 alpha, and TNF-alpha through nucleotide-binding oligomerization domain 2-mediated signaling in osteoblasts
    Shuhua Yang
    Department of Oral and Maxillofacial Surgery, Matsumoto Dental University, Shiojiri, Nagano, Japan
    J Immunol 175:1956-64. 2005
    ....
  15. ncbi request reprint Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption
    Midori Nakamura
    Department of Pediatric Dentistry, Institute for Oral Science, Matsumoto Dental University, Nagano 399 0781, Japan
    Endocrinology 144:5441-9. 2003
    ..These results suggest that bone formation is coupled with bone resorption at local sites in OPG-/- mice, and that serum RANKL levels do not reflect this coupling...
  16. ncbi request reprint Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts
    Yuko Nakamichi
    Institute for Oral Science, Matsumoto Dental University, Nagano, Japan
    J Immunol 178:192-200. 2007
    ..These results suggest that OPG suppresses the shedding of RANKL from osteoblasts and that the serum RANKL in OPG(-/-) mice exactly reflects the state of bone resorption...