Heii Arai

Summary

Affiliation: Adachi Mental Clinic
Country: Japan

Publications

  1. ncbi request reprint Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Mol Biol 363:345-54. 2006
  2. doi request reprint Basic treatment principles for psychotic disorders in patients with epilepsy
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 54:19-33. 2013
  3. doi request reprint Interictal psychotic episodes in epilepsy: duration and associated clinical factors
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 53:1088-94. 2012
  4. ncbi request reprint Intellectual prognosis of status epilepticus in adult epilepsy patients: analysis with Wechsler Adult Intelligence Scale-revised
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 46:1502-9. 2005
  5. ncbi request reprint Déjà vu experiences in schizophrenia: relations with psychopathology and antipsychotic medication
    Naoto Adachi
    Adachi Mental Clinic, Sapporo 004 0867, Japan
    Compr Psychiatry 48:592-6. 2007
  6. doi request reprint Difference in age of onset of psychosis between epilepsy and schizophrenia
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo 004 0867, Japan
    Epilepsy Res 78:201-6. 2008
  7. doi request reprint Déjà vu experiences are rarely associated with pathological dissociation
    Naoto Adachi
    Adachi Mental Clinic, Kiyota, Sapporo, Japan
    J Nerv Ment Dis 196:417-9. 2008
  8. doi request reprint Epileptic, organic and genetic vulnerabilities for timing of the development of interictal psychosis
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo, Japan
    Br J Psychiatry 196:212-6. 2010
  9. doi request reprint Two forms of déjà vu experiences in patients with epilepsy
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsy Behav 18:218-22. 2010
  10. doi request reprint Analogy between psychosis antedating epilepsy and epilepsy antedating psychosis
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo, Japan
    Epilepsia 52:1239-44. 2011

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating
    Kazuhiro Nakamura
    Department of Pathology, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Mol Biol 363:345-54. 2006
    ..Thus, maintaining proper serotonin levels during childhood may be important for mature sensorimotor gating in adulthood...
  2. doi request reprint Basic treatment principles for psychotic disorders in patients with epilepsy
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 54:19-33. 2013
    ..As for preventative procedures, optimizing seizure control by adjusting antiepileptic drugs or by surgical treatment is necessary...
  3. doi request reprint Interictal psychotic episodes in epilepsy: duration and associated clinical factors
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 53:1088-94. 2012
    ..To clarify the nature of IIP, we studied the duration of IIP episodes and their related factors...
  4. ncbi request reprint Intellectual prognosis of status epilepticus in adult epilepsy patients: analysis with Wechsler Adult Intelligence Scale-revised
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 46:1502-9. 2005
    ..To confirm whether SE produces a subsequent intellectual decline, we evaluated intellectual function prospectively in adult epilepsy patients with and without SE...
  5. ncbi request reprint Déjà vu experiences in schizophrenia: relations with psychopathology and antipsychotic medication
    Naoto Adachi
    Adachi Mental Clinic, Sapporo 004 0867, Japan
    Compr Psychiatry 48:592-6. 2007
    ..The positive relation between frequency of déjà vu experiences and the dosage of neuroleptics remains uncertain...
  6. doi request reprint Difference in age of onset of psychosis between epilepsy and schizophrenia
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo 004 0867, Japan
    Epilepsy Res 78:201-6. 2008
    ..The findings of the study suggest that the nature of epilepsy-psychosis is not fully equivalent to that of schizophrenia...
  7. doi request reprint Déjà vu experiences are rarely associated with pathological dissociation
    Naoto Adachi
    Adachi Mental Clinic, Kiyota, Sapporo, Japan
    J Nerv Ment Dis 196:417-9. 2008
    ..Two indices for pathological dissociation (DES-taxon and DES > or = 30) were not associated with déjà vu experiences. Our findings suggest that déjà vu experiences are unlikely to be core pathological dissociative experiences...
  8. doi request reprint Epileptic, organic and genetic vulnerabilities for timing of the development of interictal psychosis
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo, Japan
    Br J Psychiatry 196:212-6. 2010
    ..Age at the first psychotic episode and an interval between the onset of epilepsy and that of psychosis reflect developmental processes of interictal psychosis. However, factors relating to these indices remain unknown...
  9. doi request reprint Two forms of déjà vu experiences in patients with epilepsy
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsy Behav 18:218-22. 2010
    ..Persons with epilepsy experience two forms of déjà vu which are differently associated with their seizure recognition...
  10. doi request reprint Analogy between psychosis antedating epilepsy and epilepsy antedating psychosis
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo, Japan
    Epilepsia 52:1239-44. 2011
    ..We aimed to estimate the reliability of distinction between Psychosis-Epilepsy and Epilepsy-Psychosis by comparing their clinical characteristics...
  11. ncbi request reprint Recurrent postictal psychosis after remission of interictal psychosis: further evidence of bimodal psychosis
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 44:1218-22. 2003
    ..Methods: We reviewed the records of 14 patients with bimodal psychosis treated at a national center hospital. Clinical and psychopathological characteristics of the patients were examined...
  12. ncbi request reprint Psychoses and epilepsy: are interictal and postictal psychoses distinct clinical entities?
    Naoto Adachi
    Adachi Mental Clinic, Sapporo, Japan
    Epilepsia 43:1574-82. 2002
    ..To evaluate further the relevance of designating psychotic episodes as either postictal or interictal, we compared several biologic variables between epilepsy patients with and without psychosis...
  13. ncbi request reprint Hyperperfusion in the lateral temporal cortex, the striatum and the thalamus during complex visual hallucinations: single photon emission computed tomography findings in patients with Charles Bonnet syndrome
    N Adachi
    National Leprosarium Tama Zenshoen, Higashimurayama, Japan
    Psychiatry Clin Neurosci 54:157-62. 2000
    ..These results suggest that when elderly people suffer from eye disease, subsequent excessive cortical compensation in the lateral temporal cortex, striatum and thalamus may precipitate the development of visual hallucinations...
  14. ncbi request reprint Predictive variables of interictal psychosis in epilepsy
    N Adachi
    Adachi Mental Clinic, Kiyota, Sapporo, Japan
    Neurology 55:1310-4. 2000
    ..To evaluate which variables predict interictal psychosis in epilepsy...
  15. ncbi request reprint Frequency and age-related variables in interictal psychoses in localization-related epilepsies
    Naoto Adachi
    Adachi Mental Clinic, Kitano 7 5 12, Kiyota, Sapporo 004 0867, Japan
    Epilepsy Res 48:25-31. 2002
    ..As one of a series of multi-center studies on psychosis in epilepsy, we investigated whether the frequency of interictal psychosis differs between types of LRE...
  16. ncbi request reprint Déjà vu experiences in patients with schizophrenia
    Takuya Adachi
    Adachi Mental Clinic, Sapporo 004 0867, Japan
    Compr Psychiatry 47:389-93. 2006
    ..Their déjà vu experiences are not primarily different in nature from those of the nonclinical subjects. The decreased frequency of the experiences in the patients may suggest déjà vu experiences as nonpathologic phenomena...
  17. doi request reprint The relationship between the response of clinical symptoms and plasma olanzapine concentration, based on pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP)
    Motohiro Nozawa
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Ther Drug Monit 30:35-40. 2008
    ..Long-term olanzapine treatment with adequate plasma olanzapine concentrations could be more effective in improving some symptoms than treatment with conventional antipsychotics...
  18. ncbi request reprint Nicotine effects on mismatch negativity in nonsmoking schizophrenic patients
    Rie Inami
    Department of Psychiatry, Juntendo University School of Medicine, Koshigaya, Japan
    Neuropsychobiology 56:64-72. 2007
    ..The goal of the present study is to identify the effect of nicotine on auditory automatic processing, as reflected by mismatch negativity (MMN), in nonsmoking schizophrenic patients...
  19. ncbi request reprint Transient administration of triclofos sodium is helpful in minimizing anticonvulsants under polypharmacy
    Hideki Sakai
    Psychiatry Clin Neurosci 60:776-7. 2006
  20. ncbi request reprint Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP)
    Hitoshi Maeshima
    Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:1410-8. 2007
    ..Although GLS and GLS2 are not likely genetic risk factors for schizophrenia, changes in plasma glutamate concentration might be connected with clinical course of schizophrenia...
  21. ncbi request reprint Genetic analysis of the TrkB gene and schizophrenia in the Japanese population: Juntendo University Schizophrenia Projects (JUSP)
    Maiko Higashi
    Department of Psychiatry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Neurosci Lett 425:1-5. 2007
    ..025), the significance did not remain after Bonferroni correction. Thus, these results do not support a significant role for TrkB sequence variation in the etiology of schizophrenia...
  22. ncbi request reprint Central nervous system disease complicating Mycoplasma pneumoniae
    Tomoko Watanabe
    Psychiatry Clin Neurosci 61:577. 2007
  23. ncbi request reprint No genetic association between tryptophan hydroxylase 2 gene polymorphisms and Japanese schizophrenia
    Shinji Higashi
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo ku, Tokyo, Japan
    Psychiatr Genet 17:123. 2007
  24. ncbi request reprint Hospitalization for medical comorbidities among psychiatric patients in Tokyo
    Kotaro Hatta
    Psychiatr Serv 58:1502. 2007
  25. pmc Haloperidol plasma concentration in Japanese psychiatric subjects with gene duplication of CYP2D6
    Tohru Ohnuma
    Department of Psychiatry, Juntendo Koshigaya Hospital, 560 Fukuroyama, Koshigaya shi Saitama, 343 0032 Japan
    Br J Clin Pharmacol 56:315-20. 2003
    ....
  26. ncbi request reprint Maximal response to electroconvulsive therapy for the treatment of catatonic symptoms
    Kotaro Hatta
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo ku, Tokyo, Japan
    J ECT 23:233-5. 2007
    ..We treated catatonic symptoms with drugs within the upper limit of dosage and electroconvulsive therapy (ECT) to determine the maximal response...
  27. ncbi request reprint Effect of IL-6 polymorphism on risk of Alzheimer disease: genotype-phenotype association study in Japanese cases
    Nobuto Shibata
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Am J Med Genet 114:436-9. 2002
    ..These findings suggest that the IL-6prom G allele which may affect plasma IL-6 concentration might be a risk factor for sporadic AD in Japanese...
  28. ncbi request reprint Genetic association between Notch4 polymorphisms and Japanese schizophrenics
    Nobuto Shibata
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Psychiatr Genet 16:77-9. 2006
    ..The linkage disequilibrium of this locus indicates that there is genetic heterogeneity in the Notch4 gene. Linkage disequilibrium may differ among ethnic groups, and so a larger study should be performed in this region...
  29. ncbi request reprint The effect of IL4 +33C/T polymorphism on risk of Japanese sporadic Alzheimer's disease
    Nobuto Shibata
    Department of Psychiatry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Neurosci Lett 323:161-3. 2002
    ..We could not find any relationship between the IL4 +33C/T polymorphism and plasma IL4 concentration...
  30. pmc Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22
    Michael L Mimmack
    Department of Neurobiology, Babraham Institute, Cambridge CB2 4AT, United Kingdom
    Proc Natl Acad Sci U S A 99:4680-5. 2002
    ....
  31. ncbi request reprint Acute stress symptoms in a victim of the Indian Ocean Tsunami
    Tomoko Watanabe
    Psychiatry Clin Neurosci 60:644. 2006
  32. ncbi request reprint Visual and auditory hallucinations with excessive intake of paroxetine
    Ryo Kumagai
    Psychiatry Clin Neurosci 57:548-9. 2003
  33. ncbi request reprint No genetic association between Fyn kinase gene polymorphisms (-93A/G, IVS10+37T/C and Ex12+894T/G) and Japanese sporadic Alzheimer's disease
    Tomoko Watanabe
    Department of Psychiatry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, 343 0032, Japan
    Neurosci Lett 360:109-11. 2004
    ..These results suggest that the Fyn polymorphisms (-93A/G, IVS10+37T/C and Ex12+894T/G) investigated here have no genetic association with sporadic AD...
  34. ncbi request reprint No genetic association between tumour necrosis factor receptor II 196R polymorphism and Japanese sporadic Alzheimer's disease
    Nobuto Shibata
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Psychiatr Genet 14:53-5. 2004
    ..The results showed no genetic association between TNFRII 196R polymorphism and Alzheimer's disease. The TNFRII 196R G allele does not appear to be associated with Alzheimer's disease susceptibility in a Japanese population...
  35. ncbi request reprint Expression of nNOS and soluble guanylate cyclase in schizophrenic brain
    Hajime Baba
    Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Neuroreport 15:677-80. 2004
    ..Abnormalities of nNOS expression in the brain might contribute to the development of schizophrenia...
  36. ncbi request reprint A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT
    Tsuneyoshi Ota
    Department of Medical Imaging, National Institute of Radiological Sciences, Chiba, Japan
    Ann Nucl Med 18:187-93. 2004
    ..MP4A ratio method showed 92% sensitivity and the IMP ratio method 69% sensitivity for the diagnosis of AD. These results encourage us to develop a new SPECT tracer similar to MP4A for the diagnosis of AD...
  37. ncbi request reprint Risperidone withdrawal-related respiratory dyskinesia: a case diagnosed by spirography and fibroscopy
    Sakura Komatsu
    Department of Psychiatry, Juntendo University School of Medicine, Saitama, Japan
    Clin Neuropharmacol 28:90-3. 2005
    ..If RD is suspected, assessment should include spirography combined with fibroscopy for examination of irregularities in the rate, rhythm, and depth of respiration...
  38. ncbi request reprint Hypothesis: minimal changes in neural transmission in schizophrenia: decreased glutamatergic and GABAergic functions in the prefrontal cortex
    Tohru Ohnuma
    Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo, Tokyo 113 8421, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 29:889-94. 2005
    ..But these changes are small and failed to be statistically significant. The "receptors/transporters ratio" for each case magnified these changes, such that they became statistically significant...
  39. ncbi request reprint Decreased cell proliferation in the dentate gyrus of rats after repeated administration of cocaine
    Mika Yamaguchi
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Synapse 58:63-71. 2005
    ..These data imply that the regulation of hippocampal cell proliferation by cocaine may be involved in the development of certain symptoms of addiction, such as cognitive impairment and acquisition of behavioral sensitization...
  40. ncbi request reprint No genetic association between polymorphisms in the Fyn kinase gene and age of schizophrenic onset
    Tohru Ohnuma
    Department of Psychiatry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 343 0032, Japan
    Neurosci Lett 343:70-2. 2003
    ..The present study reports that there is no indication that the three polymorphisms in the Fyn gene are associated with the age of schizophrenic onset...
  41. pmc Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p
    Tadao Arinami
    Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki Ken, 305 8577, Japan
    Am J Hum Genet 77:937-44. 2005
    ....
  42. ncbi request reprint A quantitative near-infrared spectroscopy study: a decrease in cerebral hemoglobin oxygenation in Alzheimer's disease and mild cognitive impairment
    Heii Arai
    Department of Psychiatry, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Brain Cogn 61:189-94. 2006
    ..The NIRS system may be a potential tool for the primary screening of AD...
  43. ncbi request reprint Electroconvulsive therapy improves severe pain associated with fibromyalgia
    Chie Usui
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Pain 121:276-80. 2006
    ..We conclude that a course of ECT produced notable improvements in both intractable severe pain associated with fibromyalgia and also in terms of thalamic blood flow...
  44. ncbi request reprint No genetic association between postsynaptic density-95 gene polymorphisms and schizophrenia
    Ritsuko Kawashima
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo ku, Tokyo 113 8421, Japan
    Neurosci Lett 400:168-71. 2006
    ..The results suggested that these six polymorphisms did not affect risk for schizophrenia...
  45. ncbi request reprint Expression of Fyn, a non-receptor tyrosine kinase in prefrontal cortex from patients with schizophrenia and its correlation with clinical onset
    Tohru Ohnuma
    Department of Psychiatry, Juntendo University School of Medicine 2 1 1 Hongo, Bunkyo ku, Tokyo, Japan
    Brain Res Mol Brain Res 112:90-4. 2003
    ..8% P<0.05). In addition, the cellular Fyn mRNA signal was negatively correlated with the age of onset (r=-0.94, P=0.0026). These results suggest that an increase in Fyn expression may contribute to the pathophysiology of schizophrenia...
  46. ncbi request reprint Case reports and literature review: the association between reactivation of human herpes virus-6 and peripheral white blood cell count in patients with carbamazepine-induced hypersensitivity syndrome
    Kentaro Matsuda
    Department of Psychiatry, Juntendo Koshigaya Hospital, 560 Fukuroyama, Koshigaya shi, Saitama 343 0032, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:751-4. 2006
    ..When an increase in white blood cells are observed in HS cases at onset, immediate discontinuation of cause drug and intensive care are necessary to avoid the more severe symptoms of HS...
  47. ncbi request reprint Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat
    Juan Liu
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan
    Synapse 60:56-68. 2006
    ..Further studies are required to elucidate the biological significance of hippocampal neurogenesis in the mechanisms underlying the development of cognitive dysfunctions and the psychosis of schizophrenia...
  48. ncbi request reprint Genetic association between USF 1 and USF 2 gene polymorphisms and Japanese Alzheimer's disease
    Nobuto Shibata
    Department of Psychiatry, Juntendo University School of Medicine 2 1 1 Hongo, Bunkyo ku, Tokyo, 113 8421 Japan
    J Gerontol A Biol Sci Med Sci 61:660-2. 2006
    ..For the USF 2 gene, the two SNPs did not show significant association with onset of AD. Our study suggests that the three SNPs of the USF 1 gene and two SNPs of the USF 2 gene presented here are not associated with onset of AD...
  49. doi request reprint Association between physical restraint and drug-induced liver injury
    Kotaro Hatta
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Neuropsychobiology 56:180-4. 2007
    ....