Jay M Janz

Summary

Publications

  1. ncbi Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4
    Jay M Janz
    Anchor Therapeutics, Cambridge, Massachusetts 02142, United States
    J Am Chem Soc 133:15878-81. 2011
  2. ncbi Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells
    Boris Tchernychev
    Anchor Therapeutics, Cambridge, MA 02142, USA
    Proc Natl Acad Sci U S A 107:22255-9. 2010

Collaborators

  • Christoph Seibert
  • Boris Tchernychev
  • Pallavi Sachdev
  • Thomas P Sakmar
  • Kenneth E Carlson
  • Adam O'Shea
  • Thomas McMurry
  • Yong Ren
  • Qing Deng
  • Richard Looby
  • Lynn Haggis
  • Stephen Hunt
  • Ed McBride
  • Manija A Kazmi

Detail Information

Publications2

  1. ncbi Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4
    Jay M Janz
    Anchor Therapeutics, Cambridge, Massachusetts 02142, United States
    J Am Chem Soc 133:15878-81. 2011
    ..Adaptation and application of our findings should prove useful in further understanding pepducin modulation of GPCRs as well as enable new experimental approaches to better understand GPCR signal transduction...
  2. ncbi Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells
    Boris Tchernychev
    Anchor Therapeutics, Cambridge, MA 02142, USA
    Proc Natl Acad Sci U S A 107:22255-9. 2010
    ..We conclude that ATI-2341 is a potent and efficacious mobilizer of bone marrow PMNs and HSPCs and could represent a previously undescribed therapeutic approach for the recruitment of HSPCs before ABMT...