Ashesh B Jani

Summary

Publications

  1. pmc An electronic application for rapidly calculating Charlson comorbidity score
    William H Hall
    University of California, Davis, Department of Radiation Oncology, UC Davis Cancer Center, 4501 X Street, G126, Sacramento, CA 95817, USA
    BMC Cancer 4:94. 2004
  2. ncbi request reprint Impact of radioimmunoscintigraphy on definition of clinical target volume for radiotherapy after prostatectomy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, 5758 S Maryland Avenue, MC 9006, Chicago, IL 60637, USA
    J Nucl Med 45:238-46. 2004
  3. ncbi request reprint Influence of radioimmunoscintigraphy on postprostatectomy radiotherapy treatment decision making
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    J Nucl Med 45:571-8. 2004
  4. ncbi request reprint The application of number needed to treat (NNT) to clinical problems in radiotherapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637, USA
    Cancer Invest 22:262-70. 2004
  5. doi request reprint Pelvic shape and prostate motion: implications for target volume design and analysis of acute toxicity
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Am J Clin Oncol 32:291-5. 2009
  6. ncbi request reprint Radioimmunoscintigraphy for postprostatectomy radiotherapy: analysis of toxicity and biochemical control
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Illinois, USA
    J Nucl Med 45:1315-22. 2004
  7. ncbi request reprint Grade migration in prostate cancer: an analysis using the Surveillance, Epidemiology, and End Results registry
    A B Jani
    Department of Radiation Oncology and Urology, Emory University, Atlanta, GA, USA
    Prostate Cancer Prostatic Dis 10:347-51. 2007
  8. doi request reprint Age and grade trends in prostate cancer (1974-2003): a Surveillance, Epidemiology, and End Results Registry analysis
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Am J Clin Oncol 31:375-8. 2008
  9. ncbi request reprint Role of androgen ablation with low-dose-rate brachytherapy in the treatment of prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Clin Drug Investig 26:723-31. 2006
  10. ncbi request reprint Comparison of late gastrointestinal and genitourinary toxicity of prostate cancer patients undergoing intensity-modulated versus conventional radiotherapy using localized fields
    A B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Prostate Cancer Prostatic Dis 10:82-6. 2007

Detail Information

Publications89

  1. pmc An electronic application for rapidly calculating Charlson comorbidity score
    William H Hall
    University of California, Davis, Department of Radiation Oncology, UC Davis Cancer Center, 4501 X Street, G126, Sacramento, CA 95817, USA
    BMC Cancer 4:94. 2004
    ..Unfortunately, the use of such scales has yet to be widely integrated into either clinical practice or clinical trials research...
  2. ncbi request reprint Impact of radioimmunoscintigraphy on definition of clinical target volume for radiotherapy after prostatectomy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, 5758 S Maryland Avenue, MC 9006, Chicago, IL 60637, USA
    J Nucl Med 45:238-46. 2004
    ..The goal of this study was to evaluate the role of radioimmunoscintigraphy (RIS) directed against prostate-specific membrane antigen in modifying postprostatectomy prostate fossa clinical target volume (CTV) definition...
  3. ncbi request reprint Influence of radioimmunoscintigraphy on postprostatectomy radiotherapy treatment decision making
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    J Nucl Med 45:571-8. 2004
    ..The aim of this study was to evaluate the role of radioimmunoscintigraphy (RIS) directed against prostate-specific membrane antigen (PSMA) in influencing postradical retropubic prostatectomy (RRP) radiotherapy (RT) decision making...
  4. ncbi request reprint The application of number needed to treat (NNT) to clinical problems in radiotherapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637, USA
    Cancer Invest 22:262-70. 2004
    ....
  5. doi request reprint Pelvic shape and prostate motion: implications for target volume design and analysis of acute toxicity
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Am J Clin Oncol 32:291-5. 2009
    ..To study the impact of pelvic shape on prostate motion and the implications for radiotherapy target design and treatment outcomes...
  6. ncbi request reprint Radioimmunoscintigraphy for postprostatectomy radiotherapy: analysis of toxicity and biochemical control
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Illinois, USA
    J Nucl Med 45:1315-22. 2004
    ..Our goal was to evaluate the role of radioimmunoscintigraphy (RIS) directed against prostate-specific membrane antigen (PSMA) in influencing postprostatectomy radiotherapy (RT) toxicity and biochemical control...
  7. ncbi request reprint Grade migration in prostate cancer: an analysis using the Surveillance, Epidemiology, and End Results registry
    A B Jani
    Department of Radiation Oncology and Urology, Emory University, Atlanta, GA, USA
    Prostate Cancer Prostatic Dis 10:347-51. 2007
    ..A grade migration from WD to MD assignment has occurred, suggesting that prognostic categorizations based on grade across eras may be difficult to interpret...
  8. doi request reprint Age and grade trends in prostate cancer (1974-2003): a Surveillance, Epidemiology, and End Results Registry analysis
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Am J Clin Oncol 31:375-8. 2008
    ..The objective of this investigation was to use the Surveillance, Epidemiology, and End Results (SEER) registry to examine time trends in age and grade...
  9. ncbi request reprint Role of androgen ablation with low-dose-rate brachytherapy in the treatment of prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Clin Drug Investig 26:723-31. 2006
    ..We report a single-institution experience and analysis of the role of androgen ablation with brachytherapy in patients with prostate cancer...
  10. ncbi request reprint Comparison of late gastrointestinal and genitourinary toxicity of prostate cancer patients undergoing intensity-modulated versus conventional radiotherapy using localized fields
    A B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Prostate Cancer Prostatic Dis 10:82-6. 2007
    ..006) predicted reduction in late GI toxicity but no factors correlated with late GU toxicity. IMRT did not influence late GU toxicity but was associated with a reduction of late GI toxicity over ConvRT...
  11. doi request reprint Prostate cancer modality time trend analyses from 1973 to 2004: a Surveillance, Epidemiology, and End Results registry analysis
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, Georgia 30322, USA
    Am J Clin Oncol 33:168-72. 2010
    ..Our objectives were to analyze time trends in the use of surgery and RT and type of RT (external beam RT [EBRT], brachytherapy [Brachy] or combination EBRT + Brachy [Combo])...
  12. ncbi request reprint Early prostate cancer: hedonic prices model of provider-patient interactions and decisions
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, GA 30322, USA
    Int J Radiat Oncol Biol Phys 70:1158-68. 2008
    ..To determine the relative influence of treatment features and treatment availabilities on final treatment decisions in early prostate cancer...
  13. doi request reprint Case study of anti-1-amino-3-F-18 fluorocyclobutane-1-carboxylic acid (anti-[F-18] FACBC) to guide prostate cancer radiotherapy target design
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, Georgia 30322, USA
    Clin Nucl Med 34:279-84. 2009
    ..Here we describe a case of a prostate cancer patient who underwent radiation treatment and had an FACBC scan obtained as part of a pilot study...
  14. ncbi request reprint Biological effective dose for comparison and combination of external beam and low-dose rate interstitial brachytherapy prostate cancer treatment plans
    Ashesh B Jani
    Department of Radiation and Cellular Oncology and Urology, University of Chicago Hospitals Chicago, IL USA
    Med Dosim 29:42-8. 2004
    ..The results of this analysis can assist physicians in quantitatively determining the best combination and weighting of radiation treatment modalities for individual patients...
  15. pmc The role of indium-111 radioimmunoscintigraphy in post-radical retropubic prostatectomy management of prostate cancer patients
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, 1365 Clifton Road, NE, Suite A1300, Atlanta, GA 30322, USA
    Clin Med Res 5:123-31. 2007
    ..The larger RIS-guided target volumes do not appear to be prohibitive in increasing radiotherapy-related toxicity. Future directions of the use of RIS for post-RRP prostate cancer are discussed...
  16. pmc Biological-effective versus conventional dose volume histograms correlated with late genitourinary and gastrointestinal toxicity after external beam radiotherapy for prostate cancer: a matched pair analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, USA
    BMC Cancer 3:16. 2003
    ....
  17. doi request reprint A surveillance, epidemiology, and end results registry analysis of prostate cancer modality time trends by age
    Breanne E Terakedis
    Department of Radiation Oncology, Emory University, Atlanta, GA, USA
    Am J Clin Oncol 33:619-23. 2010
    ....
  18. doi request reprint A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy
    Kiran Devisetty
    Department of Radiation and Cellular Oncology, University of Chicago, IL, USA
    Radiother Oncol 93:298-301. 2009
    ..For V(30)>450 cc and < or =450 cc, acute GI toxicity was 33% and 8%, respectively (p=0.003)...
  19. ncbi request reprint Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy
    Loren K Mell
    Department of Radiation and Cellular Oncology, University of Chicago and University of Illinois at Chicago, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 70:1431-7. 2008
    ....
  20. ncbi request reprint Therapeutic options for a rising PSA after radical prostatectomy
    Bradley C Carthon
    Department of Hematology Oncology, Emory University, Atlanta, GA 30322, USA
    Can J Urol 20:6748-55. 2013
    ..In this review, we detail existing treatment algorithms for this group of patients as well as future therapies that show great promise...
  21. ncbi request reprint Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 66:566-70. 2005
    ..To analyze the impact of hormonal therapy (HT) on late gastrointestinal (GI) and genitourinary (GU) toxicity from external beam radiotherapy (RT)...
  22. doi request reprint External beam radiation therapy after transurethral resection of the prostate: a report on acute and late genitourinary toxicity
    Kiran Devisetty
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 77:1060-5. 2010
    ..To describe genitourinary (GU) toxicity in men with a history of transurethral resection of the prostate (TURP) treated with external beam radiation therapy (EBRT) for prostate cancer...
  23. ncbi request reprint Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome
    Michael T Milano
    Department of Radiation and Cellular Oncology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 63:354-61. 2005
    ..To assess survival, local control, and toxicity of intensity modulated radiation therapy (IMRT) in squamous cell carcinoma of the anal canal...
  24. pmc Dose-escalated radiotherapy for high-risk prostate cancer: outcomes in modern era with short-term androgen deprivation therapy
    Stanley L Liauw
    Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 77:125-30. 2010
    ..The present study reviewed the outcomes of intermediate- and high-risk men treated with RT and short-term ADT...
  25. doi request reprint Late rectal toxicity after prostate brachytherapy: influence of supplemental external beam radiation on dose-volume histogram analysis
    Kapila Kalakota
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Brachytherapy 9:131-6. 2010
    ..To describe the rate of gastrointestinal (GI) toxicity after prostate brachytherapy and describe how external beam radiation therapy (EBRT) may influence the association of rectal dose-volume histogram (DVH) parameters with rectal toxicity...
  26. ncbi request reprint Salvage therapy for locally recurrent prostate cancer after radiation
    David M Marcus
    Department of Radiation Oncolgy, Emory University, Atlanta, Georgia, USA
    Can J Urol 19:6534-41. 2012
    ..To date, there is little data describing outcomes and toxicity associated with each of these salvage modalities...
  27. ncbi request reprint Postprostatectomy target-normal structure overlap volume differences using computed tomography and radioimmunoscintigraphy images for radiotherapy treatment planning
    Andy Su
    Department of Radiation and Cellular Oncology, University of Illinois at Chicago, Chicago, IL 60637, USA
    Clin Nucl Med 31:139-44. 2006
    ....
  28. doi request reprint Boost first, eliminate systematic error, and individualize CTV to PTV margin when treating lymph nodes in high-risk prostate cancer
    Peter J Rossi
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Radiother Oncol 90:353-8. 2009
    ..The purpose of this report is to evaluate the movement of the planning target volume (PTV) in relation to the pelvic lymph nodes (PLNs) during treatment of high-risk prostate cancer...
  29. ncbi request reprint Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience
    Joseph K Salama
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    J Clin Oncol 25:4581-6. 2007
    ..To report a multicenter experience treating anal canal cancer patients with concurrent chemotherapy and intensity-modulated radiation therapy (IMRT)...
  30. doi request reprint The use of anticoagulants improves biochemical control of localized prostate cancer treated with radiotherapy
    Kevin S Choe
    Department Radiation and Cellular Oncology, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    Cancer 116:1820-6. 2010
    ..The potential antineoplastic effect of ACs was investigated in patients who received radiotherapy for localized prostate cancer...
  31. doi request reprint The association between C-reactive protein (CRP) level and biochemical failure-free survival in patients after radiation therapy for nonmetastatic adenocarcinoma of the prostate
    William A Hall
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia
    Cancer 119:3272-9. 2013
    ..Associations between prostate adenocarcinoma-specific endpoints and CRP in patients who are treated for localized disease remain unknown...
  32. doi request reprint Dose-escalated radiation therapy for intermediate-risk prostate cancer: patient selection for androgen deprivation therapy using percentage of positive cores
    Stanley L Liauw
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Cancer 115:1784-90. 2009
    ..However, the value of concurrent ADT was less certain with dose-escalated RT. Better methods of stratifying patients in this risk group may help select patients who are most likely to benefit...
  33. ncbi request reprint Hormone therapy adjuvant to external beam radiotherapy for locally advanced prostate carcinoma: a complication-adjusted number-needed-to-treat analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois 60637, USA
    Cancer 98:2351-61. 2003
    ....
  34. ncbi request reprint Management strategies for locally advanced prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Drugs Aging 23:119-29. 2006
    ..Finally, novel investigational strategies such as chemotherapy and gene therapy are being applied in an attempt to improve outcomes of locally advanced prostate cancer patients...
  35. ncbi request reprint Intensity-modulated radiotherapy in treatment of pancreatic and bile duct malignancies: toxicity and clinical outcome
    Michael T Milano
    Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 59:445-53. 2004
    ..To assess the efficacy and toxicity of intensity-modulated radiotherapy (IMRT) in pancreatic and bile duct (cholangiocarcinoma) malignancies...
  36. ncbi request reprint Adjuvant brachytherapy removes survival disadvantage of local disease extension in stage IIIC endometrial cancer: a SEER registry analysis
    Peter J Rossi
    Department of Radiation Oncology, Emory University School of Medicine, 1365 Clifton Rd, NE, Atlanta, GA 30322, USA
    Int J Radiat Oncol Biol Phys 70:134-8. 2008
    ..To assess the role of radiotherapy (RT) in women with Stage IIIC endometrial cancer...
  37. doi request reprint Salvage radiotherapy after postprostatectomy biochemical failure: does pretreatment radioimmunoscintigraphy help select patients with locally confined disease?
    Stanley L Liauw
    Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, 5758 S Maryland Avenue, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 71:1316-21. 2008
    ..Radioimmunoscintigraphy (RIS) has the potential to demonstrate early recurrences after prostatectomy and might be useful in selecting patients for salvage radiotherapy (RT)...
  38. ncbi request reprint Analysis of prostate-specific antigen rebound interval in patients with prostate cancer receiving hormonal therapy and external-beam radiation therapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Clin Prostate Cancer 3:43-8. 2004
    ..Excluding RI failures can marginally improve specificity but may possibly have an unacceptable risk of lowering sensitivity. Further work is needed to design and validate definitions of failure, which account for the RI...
  39. ncbi request reprint Postprostatectomy adjuvant versus salvage radiotherapy: a complication-adjusted number-needed-to-treat analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Cancer 103:1833-42. 2005
    ..The purpose of the current investigation was to systematically compare adjuvant versus salvage RT in a manner that incorporates both treatment efficacy and complications...
  40. doi request reprint External beam radiotherapy for prostate cancer: urinary outcomes for men with high International Prostate Symptom Scores (IPSS)
    Renuka Malik
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 80:1080-6. 2011
    ..To report the urinary outcome of men treated for prostate cancer with external beam radiotherapy (EBRT) who have pretreatment obstructive urinary symptoms (International Prostate Symptom Score [IPSS] ≥ 15)...
  41. doi request reprint External beam radiotherapy for prostate cancer patients on anticoagulation therapy: how significant is the bleeding toxicity?
    Kevin S Choe
    Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 76:755-60. 2010
    ..To characterize the bleeding toxicity associated with external beam radiotherapy for prostate cancer patients receiving anticoagulation (AC) therapy...
  42. ncbi request reprint Analysis of influence of age on acute and chronic radiotherapy toxicity in treatment of prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 65:1157-62. 2005
    ..Improved understanding of the influence of age on toxicity outcome after RT for prostate cancer can assist in treatment decision-making...
  43. ncbi request reprint Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial
    David M Schuster
    Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia Electronic address
    J Urol 191:1446-53. 2014
    ....
  44. doi request reprint High-dose radiotherapy with or without androgen deprivation therapy for intermediate-risk prostate cancer: cancer control and toxicity outcomes
    Scott Edelman
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, USA
    Int J Radiat Oncol Biol Phys 83:1473-9. 2012
    ..To evaluate the impact of short-course androgen deprivation therapy (ADT) on cancer control outcomes and toxicity in intermediate-risk prostate cancer treated with dose-escalated external beam radiotherapy (high-dose radiotherapy [HDRT])...
  45. ncbi request reprint Early prostate cancer: clinical decision-making
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Lancet 361:1045-53. 2003
    ..Here, we review the major treatment options, discuss their relative advantages and disadvantages, and provide a general approach to management of patients with early-stage prostate cancer...
  46. ncbi request reprint A case study of radiotherapy planning for a bilateral metal hip prosthesis prostate cancer patient
    Andy Su
    Department of Radiation and Cellular Oncology, The University of Chicago Hospitals, Chicago, IL 60637, USA
    Med Dosim 30:169-75. 2005
    ..The work described herein may also have applicability to other groups of patients, such as those with gynecological or other pelvic malignancies...
  47. doi request reprint Toxicity analysis of dose escalation from 75.6 gy to 81.0 gy in prostate cancer
    Natalie Xu
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Am J Clin Oncol 34:11-5. 2011
    ..Our objective was to perform a toxicity analysis of a minor dose escalation (from 75.6 to 81.0 Gy) within this "high-dose" range...
  48. ncbi request reprint Hormone therapy and radiotherapy for early prostate cancer: a utility-adjusted number needed to treat (NNT) analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, 5758 S Maryland Avenue, MC 9001, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 61:687-94. 2005
    ..To quantify, using the number needed to treat (NNT) methodology, the benefit of short-term (< or =6 months) hormone therapy adjuvant to radiotherapy in the group of patients with early (clinical stage T1-T2c) prostate cancer...
  49. doi request reprint Lymphadenectomy for patients with cervical cancer: is it of value?
    Peter J Rossi
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Surg Oncol 100:404-6. 2009
    ..The purpose of this Surveillance Epidemiology and End Results (SEER) analysis was to assess the value of lymphadenectomy (LND) in patients with cervical cancer...
  50. ncbi request reprint Approaching clinical problems in prostate cancer radiotherapy using the number needed to treat (NNT) technique
    Ashesh B Jani
    The Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Cancer Invest 24:318-27. 2006
    ..Limitations of NNT calculations based on non-randomized comparisons also are discussed...
  51. ncbi request reprint Applying population dynamics modeling to patients with lymph node positive prostate cancer
    Peter A S Johnstone
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Urol 178:1952-5; discussion 1955-6. 2007
    ..Patients with prostate cancer and positive lymph nodes are often considered to be doomed to distant failure. We applied these models to that population to examine whether those data support this presumption...
  52. ncbi request reprint Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, IL, USA
    Am J Clin Oncol 26:382-5. 2003
    ..27.0%). Thus, biochemical failure decreased with the administration of hormone therapy in this group of patients with early stage, intermediate- or high-risk prostate cancer. This finding requires validation by ongoing randomized trials...
  53. ncbi request reprint Quantitative evaluation of a cone-beam computed tomography-planning computed tomography deformable image registration method for adaptive radiation therapy
    Joshua D Lawson
    Department of Radiation Oncology, Emory University, Atlanta, Georgia, USA
    J Appl Clin Med Phys 8:2432. 2007
    ..The method is completely automated, applicable to any chosen registration algorithm, and does not require user interaction of any kind...
  54. ncbi request reprint Intensity-modulated versus conventional pelvic radiotherapy for prostate cancer: analysis of acute toxicity
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 67:147-51. 2006
    ..To provide a single-institution analysis of the influence of pelvic intensity-modulated radiotherapy (RT) on acute genitourinary (GU) and gastrointestinal (GI) toxicity...
  55. ncbi request reprint Androgen ablation adjuvant to postprostatectomy radiotherapy: complication-adjusted number needed to treat analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 64:976-81. 2004
    ..To quantify the benefits and harm of androgen ablation (AA) adjuvant to radiotherapy in the postprostatectomy setting. AA is commonly used in the management of prostate cancer...
  56. ncbi request reprint Role of external beam radiotherapy with low-dose-rate brachytherapy in treatment of prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 67:1007-11. 2006
    ..EBRT is often used in addition to low-dose-rate brachytherapy in the treatment of prostate cancer, particularly for disease with adverse features...
  57. doi request reprint Performance evaluation of Calypso 4D localization and kilovoltage image guidance systems for interfraction motion management of prostate patients
    Tomi Ogunleye
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    ScientificWorldJournal 9:449-58. 2009
    ..Implications for Calypso's role as a QA tool are discussed...
  58. ncbi request reprint Dosimetric quality endpoints for low-dose-rate prostate brachytherapy using biological effective dose (BED) vs. conventional dose
    Rachana Singh
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Med Dosim 28:255-9. 2003
    ..This methodology can be applied to analyze BED dosimetric endpoints to improve clinical outcome and reduce complications of prostate brachytherapy...
  59. doi request reprint Prostate-specific antigen halving time while on neoadjuvant androgen deprivation therapy is associated with biochemical control in men treated with radiation therapy for localized prostate cancer
    Renuka Malik
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 79:1022-8. 2011
    ..To assess whether the PSA response to neoadjuvant androgen deprivation therapy (ADT) is associated with biochemical control in men treated with radiation therapy (RT) for prostate cancer...
  60. ncbi request reprint Analysis of acute toxicity with use of transabdominal ultrasonography for prostate positioning during intensity-modulated radiotherapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 65:504-8. 2005
    ....
  61. ncbi request reprint A review of low-dose-rate prostate brachytherapy--techniques and outcomes
    David M Marcus
    Department of Radiation Oncology, Emory University School of Medicine, GA 30322, USA
    J Natl Med Assoc 102:500-10. 2010
    ..As research in prostate brachytherapy continues, it is likely that this modality will play an increasingly important role in the treatment of early-stage prostate cancer patients in the future...
  62. ncbi request reprint Extensive inguinal lymphadenectomy improves overall 5-year survival in penile cancer patients: results from the Surveillance, Epidemiology, and End Results program
    Timothy V Johnson
    Department of Urology, School of Medicine, Emory University, Atlanta, GA 30322, USA
    Cancer 116:2960-6. 2010
    ..Therefore, they assessed the frequency of inguinal lymphadenectomy and the impact of dissection extent on survival using the Surveillance, Epidemiology, and End Results (SEER) database...
  63. ncbi request reprint Opacity transfer function optimization for volume-rendered computed tomography images of the prostate
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, 5758 S Maryland Avenue, MC 9006, Chicago, IL 60637, USA
    Acad Radiol 12:761-70. 2005
    ..The selection of an opacity transfer function is essential for volume visualization. Computed tomography (CT) scans of the pelvis were used to determine an optimal opacity transfer function for use in radiotherapy...
  64. ncbi request reprint Organ motion and IMRT in prostate cancer therapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois 60637, USA
    Cancer J 9:244-6. 2003
  65. ncbi request reprint Intensity-modulated radiotherapy for neoadjuvant treatment of gastric cancer
    Brian Knab
    Department of Radiation and Cellular Oncology, The University of Chicago Hospitals, Chicago, IL, USA
    Med Dosim 31:292-7. 2006
    ..In conclusion, our study suggests a dosimetric benefit of IMRT over conventional planning, and suggests an important role for IMRT in the neoadjuvant treatment of gastric cancer...
  66. ncbi request reprint Accuracy and reliability of the endoscopic classification of chronic radiation-induced proctopathy using a novel grading method
    Kenneth D Chi
    Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, IL 60637, USA
    J Clin Gastroenterol 39:42-6. 2005
    ..To assess a novel grading method of radiation proctitis for intraobserver and interobserver agreement among endoscopists...
  67. ncbi request reprint PET lesion segmentation using automated iso-intensity contouring in head and neck cancer
    Edmund Simon
    Departmentof Radiation, Emory University, Atlanta, GA 30322, USA
    Technol Cancer Res Treat 8:249-55. 2009
    ..Iso-SUV's can also be used to study the differences between PET's role as a nuclear medicine diagnostic test versus a radiation oncology treatment planning tool...
  68. doi request reprint Influence of demographic factors on outcome of collecting duct carcinoma: a Surveillance, Epidemiology, and End Results (SEER) database analysis
    Joseph M Pepek
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Clin Genitourin Cancer 7:E24-7. 2009
    ..Collecting duct carcinoma (CDC) is a rare tumor that is difficult to analyze in a single-institution setting. The Surveillance, Epidemiology, and End Results (SEER) database was used to examine demographics and outcomes of CDC...
  69. ncbi request reprint Chronic genitourinary and gastrointestinal toxicity of prostate cancer patients undergoing pelvic radiotherapy with intensity-modulated versus 4-field technique
    Andy W Su
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Am J Clin Oncol 30:215-9. 2007
    ..To compare chronic GU and GI toxicity of pelvic radiotherapy delivered using intensity-modulated radiotherapy (IMRT) versus conventional 4-field technique...
  70. ncbi request reprint Impact of hormone therapy on acute radiotherapy toxicity in the treatment of prostate cancer
    A B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Prostate Cancer Prostatic Dis 8:224-8. 2005
    ..To analyze the impact of neoadjuvant hormone therapy (HT) on acute gastrointestinal (GI) and genitourinary (GU) toxicity from radiotherapy (RT)...
  71. ncbi request reprint The effectiveness of combining hormone therapy and radiotherapy in the treatment of prostate cancer
    Ashesh B Jani
    University of Chicago Hospitals, Department of Radiation and Cellular Oncology, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637, USA
    Expert Opin Pharmacother 5:2469-77. 2004
    ..Further data are needed in order to identify the optimum target population, combination of agents, and hormone duration, as a function of patient and disease factors...
  72. ncbi request reprint Integration of databases for radiotherapy outcomes analyses
    Ashesh B Jani
    Department of Radiation Oncology, Emory University, Atlanta, Georgia 30322, USA
    J Am Coll Radiol 4:825-31. 2007
    ..This bioinformatics database was successfully queried in a manner that allowed streamlining data flow of relevance to radiotherapy outcomes studies. Future directions of the application of this integration are discussed...
  73. ncbi request reprint Intensity-modulated radiation therapy for prostate cancer
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Clin Prostate Cancer 2:98-105. 2003
    ..In addition, future directions of prostate IMRT, both technologic and clinical, are discussed...
  74. ncbi request reprint Selecting a secondary treatment
    Nancy B Davis
    Department of Medicine, Section of Hematology Oncology, The University of Chicago Medical Center, 5841 South Maryland Avenue, MC2115, Chicago, IL 60637, USA
    Urol Clin North Am 30:403-14. 2003
    ..ketoconazole. and chemotherapy. At each interval, clinical trials should be offered since none of these maneuvers are proven to prolong life...
  75. ncbi request reprint Biochemical control and toxicity after intensity-modulated radiation therapy for prostate cancer
    S L Liauw
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
    Technol Cancer Res Treat 8:201-6. 2009
    ..By last follow-up late Grade 3+ toxicity was 2% for both GI and GU systems. In conclusion, patients treated with IMRT for prostate cancer have excellent rates of biochemical control and low rates of severe toxicity of treatment...
  76. ncbi request reprint Impact on late toxicity of using transabdominal ultrasound for prostate cancer patients treated with intensity modulated radiotherapy
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637 USA
    Technol Cancer Res Treat 4:115-20. 2005
    ..Further efforts, perhaps better undertaken in a multi-institutional setting, are needed to determine whether BAT use can significantly reduce late GI toxicity...
  77. ncbi request reprint Prostate cancer and race
    Otis W Brawley
    Department of Hematology and Oncology, Emory School of Medicine, Emory University, Atlanta, Georgia, USA
    Curr Probl Cancer 31:211-25. 2007
  78. ncbi request reprint Oral vitamin a therapy for a patient with a severely symptomatic postradiation anal ulceration: report of a case
    Josh Levitsky
    Section of Gastroenterology, Department of Medicine, University of Chicago Hospitals, Chicago, Illinois, USA
    Dis Colon Rectum 46:679-82. 2003
    ..Vitamin A seems to be very effective in the treatment of radiation-induced anorectal damage, with little toxicity and expense...
  79. ncbi request reprint Sparing of the penile bulb and proximal penile structures with intensity-modulated radiation therapy for prostate cancer
    J Kao
    University of Chicago University of Illinois at Chicago Department of Radiation Oncology, 5758 S Maryland Avenue, MC 9006, Chicago, IL 60637, USA
    Br J Radiol 77:129-36. 2004
    ..4% vs 21.9%, p=0.003) but the volumes of bladder receiving 70 Gy were similar (p=0.3). IMRT may potentially reduce long term sexual morbidity by reducing the dose to the majority of the penile bulb...
  80. ncbi request reprint Changing face and different countenances of prostate cancer: racial and geographic differences in prostate-specific antigen (PSA), stage, and grade trends in the PSA era
    A B Jani
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Int J Cancer 96:363-71. 2001
    ..For whites, the trends are more complex and more dependent on region. These findings should be used for future clinical and health-policy decisions in the screening and treatment of prostate cancer...
  81. ncbi request reprint The impact of age and comorbidity on survival outcomes and treatment patterns in prostate cancer
    W H Hall
    Department of Radiation Oncology, UC Davis Cancer Center, University of California, Davis, 4501 X Street, Sacramento, CA 95817, USA
    Prostate Cancer Prostatic Dis 8:22-30. 2005
    ..Several clinical vignettes are provided to demonstrate the potential clinical utility of the CCI as applied to prostate cancer...
  82. ncbi request reprint 'Insignificant' prostate cancer on biopsy: pathologic results from subsequent radical prostatectomy
    P A S Johnstone
    Radiation Oncology Department, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USA
    Prostate Cancer Prostatic Dis 10:237-41. 2007
    ..Thus, reasoned accounting should be made of other data before undertaking a course of radiation therapy as monotherapy, particularly prostate-specific antigen kinetics and potential molecular markers...
  83. ncbi request reprint Equivalent racial outcome after conformal radiotherapy for prostate cancer: a single departmental experience
    P P Connell
    Department of Radiation and Cellular Oncology, University of Chicago, Micheal Reese Center for Radiation Therapy, Chicago, IL, USA
    J Clin Oncol 19:54-61. 2001
    ..36). CONCLUSION: Conformal RT is equally effective for AA and W patients. More research is needed in order to understand and correct the advanced presentations in AA men. These data suggest a need for early screening in AA populations...
  84. ncbi request reprint Influence of intensity-modulated radiotherapy on acute genitourinary and gastrointestinal toxicity in the treatment of localized prostate cancer
    Ashesh B Jani
    Dept of Radiation and Cellular Oncology, University of Chicago Hospitals, 5758 S Maryland Ave, MC 9006, Chicago, IL 60637, USA
    Technol Cancer Res Treat 6:11-5. 2007
    ....
  85. ncbi request reprint Is there an association between multiple myeloma and prostate cancer?
    Johnny Kao
    Department of Radiation and Cellular Oncology, University of Chicago, 5758 South Maryland Avenue, MC 9006, Chicago, IL 60637, USA
    Med Hypotheses 63:226-31. 2004
    ....
  86. ncbi request reprint Race and disparities in health
    Otis W Brawley
    Hematology and Oncology, Emory School of Medicine, Department of Epidemiology, Rollins School of Public Health, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA
    Curr Probl Cancer 31:114-22. 2007
  87. ncbi request reprint Sentinel lymph node versus axillary lymph node dissection for early-stage breast carcinoma: a comparison using a utility-adjusted number needed to treat analysis
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, Illinois 60637, USA
    Cancer 97:359-66. 2003
    ..The current study was performed to compare the value of sentinel lymph node dissection (SND) and axillary lymph node dissection (AND) in improving the utility-adjusted survival for early-stage breast carcinoma patients...
  88. ncbi request reprint Analysis of impact of age and race on biochemical control after radiotherapy in different prostate cancer settings
    Ashesh B Jani
    Department of Radiation and Cellular Oncology, University of Chicago Hospitals, Chicago, Illinois 60637, USA
    Urology 66:124-9. 2005
    ..Proper understanding of these prognostic factors can assist in both treatment decision-making and the general understanding of the natural history of prostate cancer...
  89. ncbi request reprint A critical review of variables affecting the accuracy and false-negative rate of sentinel node biopsy procedures in early breast cancer
    Vani Vijayakumar
    Nuclear Medicine Section, Department of Radiology, University of Texas Medical Branch, Galveston, Texas 77555 0793, USA
    Nucl Med Commun 26:395-405. 2005
    ..In this review, the factors that influence the success of different techniques are examined, and studies which have investigated false-negative rates and/or sentinel lymph node identification rates are summarized...