Research Topics
| C R NwokochaSummaryAffiliation: University of the West Indies Country: Jamaica Publications
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Detail Information
Publications
Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley ratsChukwuemeka R Nwokocha
Department of Basic Medical Sciences Physiology Section, The University of the West Indies, Mona, Kingston 7, Jamaica
Pharm Biol 50:1436-41. 2012..Annona muricata Linn (Annonaceae) (soursop) is a food plant reported to have antihypertensive properties...
Serum lipids, proteins and electrolyte profiles in rats following total body irradiationC R Nwokocha
Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
West Indian Med J 61:117-21. 2012....
Experimental malaria: the in vitro and in vivo blood pressure paradoxC R Nwokocha
Department of Basic Medical Sciences, University of the West Indies, Kingston, Jamaica
Cardiovasc J Afr 23:98-102. 2012..Therefore insight into the complexity of the pathogenesis of malaria is vital to understand the disease, particularly as it relates to blood pressure...
Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague-Dawley ratsChukwuemeka R Nwokocha
Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston, Jamaica
Pharm Biol 50:1096-102. 2012..We investigated the possible mechanisms of action of its aqueous extract and its effect on cytochromes P450 (CYP) enzyme activities...
Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liverChukwuemeka R Nwokocha
Dept of Basic Medical Sciences, University of the West Indies, Mona, Kingston 7, Jamaica
Food Chem Toxicol 50:2070-3. 2012..We examined the ability of fruit extract to protect against mercury (Hg), lead (Pb) and cadmium (Cd) accumulation in the liver...
Antihypertensive properties of Allium sativum (garlic) on normotensive and two kidney one clip hypertensive ratsC R Nwokocha
Niger J Physiol Sci 26:213-8. 2011..AGE caused a decrease in blood pressure and bradycardia by direct mechanism not involving the cholinergic pathway in both normotensive and 2K1C rats, suggesting a likely involvement of peripheral mechanism for hypotension...
In vivo distribution of lead in male and female rats after intraperitoneal and oral administrationC R Nwokocha
Department of Basic Medical Sciences, University of the West Indies Mona Jamaica, West Indies
Toxicol Ind Health 28:131-5. 2012..05) higher than the males. Our findings suggest that lead retention and the organ distribution varied depending upon the sex and route of lead administration...
Comparative study on the efficacy of Allium sativum (garlic) in reducing some heavy metal accumulation in liver of wistar ratsChukwuemeka R Nwokocha
Department of Basic Medical Sciences, University of the West Indies, Mona, Jamaica
Food Chem Toxicol 50:222-6. 2012..This study was undertaken to compare the therapeutic efficacy and protective ability of garlic extracts on reducing toxicity induced by mercury, lead and cadmium in the liver...
Effects of total body irradiation on fatty acid and total lipid content of ratsNwokocha Chukwuemeka
Department of Basic Medical Sciences, University of the West Indies, Jamaica
Pak J Pharm Sci 25:169-73. 2012..The consequences of our observation are not known yet, but could point to some possible clinical intervention...
Estimation of absorbed cadmium in tissues of male and female albino rats through different routes of administrationC R Nwokocha
Dept of Basic Medical Sciences, University of the West Indies, Mona
Niger J Physiol Sci 26:97-101. 2011..The concentrations of cadmium were analyzed in tissues (lung, stomach, kidney, heart, spleen, blood) by AAS. There were significant (P...
Specificity of vascular reactivity and altered response in experimental malariaC R Nwokocha
Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
West Indian Med J 60:330-5. 2011..In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between the parasitized erythrocytes and vascular endothelial cells and that it could be tissue specific...
Altered vascular reactivity induced by malaria parasitesC R Nwokocha
Section of Physiology, Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica, West Indies
West Indian Med J 60:13-8. 2011..In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between parasitized erythrocytes and vascular endothelial cells...
Comparative study on the efficacy of Garcinia kola in reducing some heavy metal accumulation in liver of Wistar ratsC R Nwokocha
Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica
J Ethnopharmacol 135:488-91. 2011..Garcinia kola has the highest hepatoprotective effect to Cd followed by Hg and least protection against Pb toxicity in rats and its administration is beneficial in reducing heavy metal accumulation in the liver...
