C R Nwokocha

Summary

Affiliation: University of the West Indies
Country: Jamaica

Publications

  1. pmc Comparative study on the hepatoprotection to heavy metals of Zingiber officinale
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Nigeria
    Pharmacognosy Res 4:208-13. 2012
  2. pmc Comparative analysis on the effect of palm oil (Elaeis guineensis) in reducing cadmium and lead accumulation in liver of Wistar rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica, Nigeria
    Pharmacognosy Res 4:214-8. 2012
  3. doi request reprint Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase
    Chukwuemeka R Nwokocha
    Physiology Section, Department of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica
    Cardiovasc Toxicol 13:357-63. 2013
  4. doi request reprint Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences Physiology Section, The University of the West Indies, Mona, Kingston 7, Jamaica
    Pharm Biol 50:1436-41. 2012
  5. ncbi request reprint Serum lipids, proteins and electrolyte profiles in rats following total body irradiation
    C R Nwokocha
    Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
    West Indian Med J 61:117-21. 2012
  6. pmc Experimental malaria: the in vitro and in vivo blood pressure paradox
    C R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Kingston, Jamaica
    Cardiovasc J Afr 23:98-102. 2012
  7. doi request reprint Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague-Dawley rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston, Jamaica
    Pharm Biol 50:1096-102. 2012
  8. doi request reprint Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liver
    Chukwuemeka R Nwokocha
    Dept of Basic Medical Sciences, University of the West Indies, Mona, Kingston 7, Jamaica
    Food Chem Toxicol 50:2070-3. 2012
  9. ncbi request reprint Antihypertensive properties of Allium sativum (garlic) on normotensive and two kidney one clip hypertensive rats
    C R Nwokocha
    Niger J Physiol Sci 26:213-8. 2011
  10. doi request reprint In vivo distribution of lead in male and female rats after intraperitoneal and oral administration
    C R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies Mona Jamaica, West Indies
    Toxicol Ind Health 28:131-5. 2012

Collaborators

Detail Information

Publications18

  1. pmc Comparative study on the hepatoprotection to heavy metals of Zingiber officinale
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Nigeria
    Pharmacognosy Res 4:208-13. 2012
    ..Zingiber officinale (Zingiberaceae) is a herb used for culinary and therapeutic purposes due to its anti-inflammatory and antioxidant potentials...
  2. pmc Comparative analysis on the effect of palm oil (Elaeis guineensis) in reducing cadmium and lead accumulation in liver of Wistar rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica, Nigeria
    Pharmacognosy Res 4:214-8. 2012
    ..Palm oil from Elaeis guineensis is an edible nutrient substance with anti-inflammatory and antioxidant properties. We examined its protective effect against lead (Pb) and cadmium (Cd) accumulation in the liver...
  3. doi request reprint Apocynin ameliorates cadmium-induced hypertension through elevation of endothelium nitric oxide synthase
    Chukwuemeka R Nwokocha
    Physiology Section, Department of Basic Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica
    Cardiovasc Toxicol 13:357-63. 2013
    ..Apocynin was effective in reducing cadmium-induced elevated blood pressures through elevation of eNOS. Inhibition of NADPH oxidase activity may be a useful strategy for prevention and treatment of cadmium-induced hypertension. ..
  4. doi request reprint Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences Physiology Section, The University of the West Indies, Mona, Kingston 7, Jamaica
    Pharm Biol 50:1436-41. 2012
    ..Annona muricata Linn (Annonaceae) (soursop) is a food plant reported to have antihypertensive properties...
  5. ncbi request reprint Serum lipids, proteins and electrolyte profiles in rats following total body irradiation
    C R Nwokocha
    Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
    West Indian Med J 61:117-21. 2012
    ....
  6. pmc Experimental malaria: the in vitro and in vivo blood pressure paradox
    C R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Kingston, Jamaica
    Cardiovasc J Afr 23:98-102. 2012
    ..Therefore insight into the complexity of the pathogenesis of malaria is vital to understand the disease, particularly as it relates to blood pressure...
  7. doi request reprint Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague-Dawley rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston, Jamaica
    Pharm Biol 50:1096-102. 2012
    ..We investigated the possible mechanisms of action of its aqueous extract and its effect on cytochromes P450 (CYP) enzyme activities...
  8. doi request reprint Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liver
    Chukwuemeka R Nwokocha
    Dept of Basic Medical Sciences, University of the West Indies, Mona, Kingston 7, Jamaica
    Food Chem Toxicol 50:2070-3. 2012
    ..We examined the ability of fruit extract to protect against mercury (Hg), lead (Pb) and cadmium (Cd) accumulation in the liver...
  9. ncbi request reprint Antihypertensive properties of Allium sativum (garlic) on normotensive and two kidney one clip hypertensive rats
    C R Nwokocha
    Niger J Physiol Sci 26:213-8. 2011
    ..AGE caused a decrease in blood pressure and bradycardia by direct mechanism not involving the cholinergic pathway in both normotensive and 2K1C rats, suggesting a likely involvement of peripheral mechanism for hypotension...
  10. doi request reprint In vivo distribution of lead in male and female rats after intraperitoneal and oral administration
    C R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies Mona Jamaica, West Indies
    Toxicol Ind Health 28:131-5. 2012
    ..05) higher than the males. Our findings suggest that lead retention and the organ distribution varied depending upon the sex and route of lead administration...
  11. doi request reprint Comparative study on the efficacy of Allium sativum (garlic) in reducing some heavy metal accumulation in liver of wistar rats
    Chukwuemeka R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona, Jamaica
    Food Chem Toxicol 50:222-6. 2012
    ..This study was undertaken to compare the therapeutic efficacy and protective ability of garlic extracts on reducing toxicity induced by mercury, lead and cadmium in the liver...
  12. ncbi request reprint Effects of total body irradiation on fatty acid and total lipid content of rats
    Nwokocha Chukwuemeka
    Department of Basic Medical Sciences, University of the West Indies, Jamaica
    Pak J Pharm Sci 25:169-73. 2012
    ..The consequences of our observation are not known yet, but could point to some possible clinical intervention...
  13. ncbi request reprint Estimation of absorbed cadmium in tissues of male and female albino rats through different routes of administration
    C R Nwokocha
    Dept of Basic Medical Sciences, University of the West Indies, Mona, Jamaica, West Indies
    Niger J Physiol Sci 26:97-101. 2011
    ..506 ± 0.074 vs 0.748 ± 0.147), stomach (0.045 ± 0.020 vs 0.001± 0.001) and blood (1.126 ± 0.001 vs 0.114 ± 0.001). Our results suggest that Cd accumulation in the various organs was sex and route of exposure-dependent in rats...
  14. doi request reprint Comparative study on the efficacy of Garcinia kola in reducing some heavy metal accumulation in liver of Wistar rats
    C R Nwokocha
    Department of Basic Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica
    J Ethnopharmacol 135:488-91. 2011
    ..Garcinia kola has the highest hepatoprotective effect to Cd followed by Hg and least protection against Pb toxicity in rats and its administration is beneficial in reducing heavy metal accumulation in the liver...
  15. ncbi request reprint Specificity of vascular reactivity and altered response in experimental malaria
    C R Nwokocha
    Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
    West Indian Med J 60:330-5. 2011
    ..In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between the parasitized erythrocytes and vascular endothelial cells and that it could be tissue specific...
  16. ncbi request reprint Altered vascular reactivity induced by malaria parasites
    C R Nwokocha
    Section of Physiology, Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica, West Indies
    West Indian Med J 60:13-8. 2011
    ..In this study, we have examined the possibility that there is altered vascular reactivity due to the direct interaction between parasitized erythrocytes and vascular endothelial cells...
  17. ncbi request reprint Proteins and liver function changes in rats following cumulative total body irradiations
    C R Nwokocha
    Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
    West Indian Med J 61:773-7. 2012
    ..The aim of this research is to sequentially document the effect of total body radiation on body function utilizing the sequential changes in liver function enzymes and proteins in rats...
  18. ncbi request reprint Effect of Gongronema latifolium ethanol leaf extract on gastric acid secretion and cytoprotection in streptozotocin-induced diabetic rats
    D U Owu
    Department of Basic Medical Sciences, The University of the West Indies, Kingston 7, Jamaica
    West Indian Med J 61:853-60. 2012
    ..This study aimed to provide a pharmacological basis to the medicinal use ofGongronema latifolium as an antidiabetic and antiulcerogenic agent in diabetes mellitus...