Deepali Jain

..Clinicians should consider that the occurrence of hemophagocytosis in the appropriate geographical area could be due to dengue virus infection and present with pancytopenia...

..The authors describe a 4-year-old girl with an extraskeletal osteosarcoma in the lateral abdominal wall...

..We present the first case of ectopic hidradenoma papilleferum presenting as a cystic swelling in the lower eyelid. A brief review of literature is included...

..It needs to be differentiated from primary clear cell carcinoma of the GB with the help of immunohistochemistry...

..Also, the pathogenesis of HCC in alcoholic cirrhosis (ALC) in which the pathologic and clinical features are very similar to those of nonalcoholic fatty liver cirrhosis (NAFLC) is unknown...

..Herein we describe 2 unique cases of tubulovillous adenoma of the anal canal with review of the literature. The diagnosis of these lesions is clinically important as they may undergo malignant transformation...

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..Histology revealed a highly cellular tumor with closely packed fascicles of spindle cells. Immunohistochemically, the tumor cells expressed vimentin...

..Extensive medlar search showed presence of only 28 cases of psammocarcinoma of ovary reported till date...

..Even after thorough search no extraovarian primary site could be found. Based on overall clinicopathologic correlation, a diagnosis of metastatic signet ring cell adenocarcinoma of bone marrow with uncertain primary was established...

..Hypocellular variants of acute myeloid leukemia are very rare and almost always occur in old aged patients. In contrast, hypocellular acute lymphoblastic leukemia usually occurs in children...

..We herein report 4 interesting cases of hepatitis C virus-, alcohol-, and nonalcoholic fatty liver disease-associated end-stage liver disease with coexisting HCC and multiple large von-Meyenburg complexes...

..The patient was treated with hyper-CVAD chemotherapy regimen, resulting in a complete response...

..Approximately 75% of patients are affected with Candida species. Scopulariopsis species affecting prosthetic valve is rarely reported in the literature...

..We describe an interesting case showing features of mucinous cystadenoma arising in the ureter in which the tumor was incidentally detected in a 53-year-old man with significant secondary hydronephrosis and nonfunctioning kidney...

..We herein present the first case of sclerosing mediastinitis involving the ascending aorta as part of a multifocal fibrosclerotic disorder...

..Cases of APL in Down syndrome (DS) have been described in the literature rarely and it is rarer still to find the microgranular variant (M3v) of APL in trisomy 21 patients...

..A rare hematologic manifestation is in the form of dyserythropoeisis. Herein, we present the case of a 9-year-old female with severe dyserythropoeisis associated with parvovirus infection...

..Spinal cord teratomas are uncommon tumours. The diagnosis is rarely suspected before surgery and final diagnosis is invariably made at histopathological examination...

..Non-functioning pituitary adenomas (NFPA) are characterized by the lack of clinical syndrome as compared to functioning adenomas (FA) but not all functioning adenomas have clinical effects. Their exact incidence varies in different series...

..We discuss possible mechanisms and clinical characteristics of extrarenal Wilms' tumor and present a short review of the literature...

..Pathologic examination revealed a mature teratoma with pulmonary differentiation. To the best of our knowledge this is the second case of spinal teratoma with pulmonary differentiation...

..Proliferative indices were very low (<1%) and tumor suppressor gene protein expression was not seen in the present study. Cortical dysplasia of the surrounding brain was observed in 37.3% of cases...

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..Interhemisperic lipomas are almost always associated with hypogenesis or agenesis of the corpus callosum. These lesions are stable...

..As a consequence, very little is known about its histogenesis, clinicopathologic features and prognosis. We herein describe a case of renal carcinoid with atypical features...

..p53 and MDM2 proteins expression are not common in ependymomas; however, they are seen in higher grades only and may be involved in the tumor progression...

..These findings suggest that YAP1 may play an important role in normal human brain development and that it could represent a new target in human brain tumors...

..Five of the patients were females, one was male, and the sex of one neonate could not be ascertained. One of the neonates was from a twin pregnancy; the other twin was normal...

..Thus, this small series confirms that stereotactic procedures involving multiple bits are associated with a high diagnostic yield...

..Congenital myopathies are rare. Through this article, the authors want to present a clinicopathological analysis of 25 new cases...

..Electron microscopy confirmed the ependymal nature of these tumors. Clear cell ependymomas are rare and aggressive tumors. More cases need to be reported to determine their therapeutic responsiveness and prognosis...

..The pathogenesis is uncertain and they were believed to have a good prognosis until it was recently shown, from study of explant livers, that they had progressed to end stage disease, needing liver transplantation...

..The present case report highlights the rare occurrence of osseous metaplasia in thymomas and the diagnostic challenge that it can pose, especially if it is associated with cystic degeneration...

..This report highlights the importance of histochemistry and electron microscopy for accurate diagnosis; otherwise TAM can be misdiagnosed on clinical grounds as a metabolic or mitochondrial myopathy...

..To the best of the authors' knowledge, involvement of bone by B. coli has never been reported, and this case is the first documented instance of cervical cord compression due to B. coli osteomyelitis of the spine in the literature...

..Melanin production in medullary carcinoma is extremely uncommon...

..Although p63 expression is significantly associated with higher histological grade of meningiomas, it may not be considered as a sole biomarker to assess aggressive behavior of the tumor...

..All patients had thrombocytopenia, bleeding symptoms and haemolytic anaemia with positive direct Coombs test at presentation. We discuss the aetiopathogenic, clinical, therapeutic and natural history of Evans syndrome...

..Certain genetic causes, such as Marfan syndrome and congenital bicuspid aortic valve disease, are well known. However, other rarer genetic and nongenetic causes of aortic disease exist...

..Rarely, they have been reported at the cerebellopontine (CP) angle. Here we describe an interesting case of CP angle chondroma which was clinically and radiologically diagnosed as schwannoma and meningioma...

..We investigated the functional effect of constitutive BRAF activation in normal human neural stem and progenitor cells to determine its role in tumor induction in the brain...

..To the best of our knowledge, spinal teratoma with renal component has not been described previously...

..Cellular leiomyoma is characterized by significantly increased cellularity and may mimic malignant tumors. Our aim was to differentiate these from other malignant small round-cell tumors...

..We report the clinical and pathologic findings of a case of primary epithelioid hemangioendothelioma of the urinary bladder in a 17-years-old boy. The tumor was treated by transurethral resection...

..Right hemicolectomy was performed with clinical and radiological suspicion of malignancy. This is the first reported case of XGI in ascending colon with mucosal involvement...

..We report a case of a 59-year-old male who presented with a large tumor in the scalp. Histopathologic examination revealed an apocrine mixed tumor with prominent pilomatricomal differentiation...

..CONCLUSION: The case highlights the potential pitfall of cytology in diagnosing NF, especially because of unusual site and morphologic overlap...

..The expression of these proteins was correlated with aggressive tumor behavior. All these indicate significant diagnostic, therapeutic, and prognostic roles for these proteins...

..The findings suggest that the normally limited expression of MECP2 in visual pathway neurons may underlie the intact vision observed in Rett syndrome...

..This comprehensive and up-to-date review describes the key clinical, gross, and histologic findings for 16 distinct entities. It also provides differential diagnoses and key facts to differentiate between similar appearing tumors...

..Pathological examination in both cases revealed a uterus-like structure with evidence of fresh and old hemorrhage. The rarity of this lesion and its association with diastematomyelia requires documentation...