Shevin T Jacob

Summary

Publications

  1. pmc Mycobacterium tuberculosis bacteremia in a cohort of HIV-infected patients hospitalized with severe sepsis in Uganda-high frequency, low clinical sand derivation of a clinical prediction score
    Shevin T Jacob
    University of Washington, Department of Medicine, Seattle, Washington, USA
    PLoS ONE 8:e70305. 2013
  2. pmc Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research
    Shevin T Jacob
    International Respiratory and Severe Illness Center INTERSECT, Department of Medicine, University of Washington, 325 9th Ave, Box 359927, Seattle, WA 98104, USA
    BMC Med 11:107. 2013
  3. pmc The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: a prospective intervention study*
    Shevin T Jacob
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA
    Crit Care Med 40:2050-8. 2012
  4. pmc Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 4:e7782. 2009
  5. pmc Fitting a square peg into a round hole: are the current Surviving Sepsis Campaign guidelines feasible for Africa?
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Box 359927, 325 Ninth Avenue, Seattle, WA 98104, USA
    Crit Care 15:117. 2011
  6. ncbi request reprint Treatment of severe sepsis with artemether-lumefantrine is associated with decreased mortality in Ugandan patients without malaria
    CHRISTOPHER C MOORE
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Am J Trop Med Hyg 80:723-8. 2009
  7. doi request reprint Clinical care for severe influenza and other severe illness in resource-limited settings: the need for evidence and guidelines
    Justin R Ortiz
    International Respiratory and Severe Illness Center INTERSECT, University of Washington, Seattle, WA, USA
    Influenza Other Respir Viruses 7:87-92. 2013
  8. doi request reprint Clinical research during a public health emergency: a systematic review of severe pandemic influenza management
    Justin R Ortiz
    Department of Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 41:1345-52. 2013
  9. pmc Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis
    Rituparna Das
    Department of Medicine, Yale School of Medicine, New Haven, CT 06510, USA
    Proc Natl Acad Sci U S A 110:E2997-3006. 2013
  10. pmc A post-trial assessment of factors influencing study drug adherence in a randomized biomedical HIV-1 prevention trial
    Shevin T Jacob
    Department of Medicine, University of Washington, Seattle, WA, USA
    AIDS Behav 15:897-904. 2011

Detail Information

Publications10

  1. pmc Mycobacterium tuberculosis bacteremia in a cohort of HIV-infected patients hospitalized with severe sepsis in Uganda-high frequency, low clinical sand derivation of a clinical prediction score
    Shevin T Jacob
    University of Washington, Department of Medicine, Seattle, Washington, USA
    PLoS ONE 8:e70305. 2013
    ..In a cohort of hospitalized HIV-infected Ugandan patients with severe sepsis, we report the frequency, management and outcomes of patients with MTB bacteremia and propose a risk score based on clinical predictors of MTB bacteremia...
  2. pmc Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research
    Shevin T Jacob
    International Respiratory and Severe Illness Center INTERSECT, Department of Medicine, University of Washington, 325 9th Ave, Box 359927, Seattle, WA 98104, USA
    BMC Med 11:107. 2013
    ....
  3. pmc The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: a prospective intervention study*
    Shevin T Jacob
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA
    Crit Care Med 40:2050-8. 2012
    ..In sub-Saharan Africa, sepsis is an important cause of mortality. Optimal sepsis management including fluid resuscitation, early antibiotic administration, and patient monitoring is limited by lack of supplies and skilled health workers...
  4. pmc Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 4:e7782. 2009
    ..We conducted a prospective observational study reporting the management and outcomes of severely septic patients in two Ugandan hospitals. We describe their epidemiology, management, and clinical correlates for mortality...
  5. pmc Fitting a square peg into a round hole: are the current Surviving Sepsis Campaign guidelines feasible for Africa?
    Shevin T Jacob
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Box 359927, 325 Ninth Avenue, Seattle, WA 98104, USA
    Crit Care 15:117. 2011
    ..Comprehensive, evidence-based guidelines combined with innovative approaches to sepsis management in LMICs are required to make a meaningful impact on worldwide sepsis survival...
  6. ncbi request reprint Treatment of severe sepsis with artemether-lumefantrine is associated with decreased mortality in Ugandan patients without malaria
    CHRISTOPHER C MOORE
    Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Am J Trop Med Hyg 80:723-8. 2009
    ..7%, SE = 15.2 versus 58.3%, SE = 3.7; Log rank chi(2) 3.94, P = 0.041). Research into the properties of A-L is needed to improve treatment of sepsis without compromising malarial susceptibility...
  7. doi request reprint Clinical care for severe influenza and other severe illness in resource-limited settings: the need for evidence and guidelines
    Justin R Ortiz
    International Respiratory and Severe Illness Center INTERSECT, University of Washington, Seattle, WA, USA
    Influenza Other Respir Viruses 7:87-92. 2013
    ....
  8. doi request reprint Clinical research during a public health emergency: a systematic review of severe pandemic influenza management
    Justin R Ortiz
    Department of Medicine, University of Washington, Seattle, WA, USA
    Crit Care Med 41:1345-52. 2013
    ....
  9. pmc Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis
    Rituparna Das
    Department of Medicine, Yale School of Medicine, New Haven, CT 06510, USA
    Proc Natl Acad Sci U S A 110:E2997-3006. 2013
    ..Our data place MIF in a crucial upstream position in the innate immune response to mycobacteria and suggest that commonly occurring low expression MIF alleles confer an increased risk of TB disease in some populations. ..
  10. pmc A post-trial assessment of factors influencing study drug adherence in a randomized biomedical HIV-1 prevention trial
    Shevin T Jacob
    Department of Medicine, University of Washington, Seattle, WA, USA
    AIDS Behav 15:897-904. 2011
    ....