Carmine Zoccali

Summary

Country: Italy

Publications

  1. ncbi request reprint Inflammation markers, adhesion molecules, and all-cause and cardiovascular mortality in patients with ESRD: searching for the best risk marker by multivariate modeling
    Giovanni Tripepi
    National Research Council and Institute of Biomedicine Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Am Soc Nephrol 16:S83-8. 2005
  2. ncbi request reprint Asymmetric dimethylarginine (ADMA): a cardiovascular and renal risk factor on the move
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Cal, Italy
    J Hypertens 24:611-9. 2006
  3. ncbi request reprint Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension
    Carmine Zoccali
    Consiglio Nazionale delle Ricerche Instituto di Bio Medicina, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Ospedali Riuniti, 89124 Reggio Calabria, Italy
    J Am Soc Nephrol 17:S61-3. 2006
  4. ncbi request reprint A green light for troponin T in the cardiovascular risk stratification of continuous ambulatory peritoneal dialysis patients?
    C Zoccali
    Nephrology, Hypertension and Renal Transplantation, Consiglio Nazionale delle Richerche CNR Institutio di Biomedicina IBIM, Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Cal, Italy
    Kidney Int 70:408-10. 2006
  5. pmc Homoarginine and mortality in pre-dialysis chronic kidney disease (CKD) patients
    Pietro Ravani
    Department of Medicine and Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 8:e72694. 2013
  6. doi request reprint Uric acid, hypertension, and cardiovascular and renal complications
    Carmine Zoccali
    CNR National Research Council Italy Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension Unit and Nephrology, Hypertension and Renal Transplantation Unit, Ospedali Riuniti, Reggio Calabria, 89124, Italy
    Curr Hypertens Rep 15:531-7. 2013
  7. pmc Cultural adaptation and validation of the "Kidney Disease and Quality of Life--Short Form (KDQOL-SF™) version 1.3" questionnaire in Egypt
    Samar Abd Elhafeez
    Epidemiology Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt
    BMC Nephrol 13:170. 2012
  8. pmc Pro-inflammatory cytokines and bone fractures in CKD patients. An exploratory single centre study
    Vincenzo Panuccio
    Nephrology, Dialysis, Hypertension and Renal Transplantation Unit Azienda Ospedaliera, Via Vallone Petrara, 89124, Reggio Calabria, Italy
    BMC Nephrol 13:134. 2012
  9. doi request reprint FGF23: a mature renal and cardiovascular risk factor?
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation Division and CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Blood Purif 36:52-7. 2013
  10. pmc Pulmonary congestion predicts cardiac events and mortality in ESRD
    Carmine Zoccali
    National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Am Soc Nephrol 24:639-46. 2013

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Inflammation markers, adhesion molecules, and all-cause and cardiovascular mortality in patients with ESRD: searching for the best risk marker by multivariate modeling
    Giovanni Tripepi
    National Research Council and Institute of Biomedicine Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Am Soc Nephrol 16:S83-8. 2005
    ..However, the risk estimate by CRP being reasonably close to that of IL-6, CRP may be a cheap alternative to IL-6 in clinical practice...
  2. ncbi request reprint Asymmetric dimethylarginine (ADMA): a cardiovascular and renal risk factor on the move
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Cal, Italy
    J Hypertens 24:611-9. 2006
    ..ADMA may be at the crossroad of the atherosclerosis process and may represent an important factor in the high risk associated with renal insufficiency...
  3. ncbi request reprint Endothelial dysfunction and the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension
    Carmine Zoccali
    Consiglio Nazionale delle Ricerche Instituto di Bio Medicina, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Ospedali Riuniti, 89124 Reggio Calabria, Italy
    J Am Soc Nephrol 17:S61-3. 2006
    ..A dysfunctional endothelium may represent a critical link accounting for the risk for both renal impairment and cardiovascular complications in essential hypertension...
  4. ncbi request reprint A green light for troponin T in the cardiovascular risk stratification of continuous ambulatory peritoneal dialysis patients?
    C Zoccali
    Nephrology, Hypertension and Renal Transplantation, Consiglio Nazionale delle Richerche CNR Institutio di Biomedicina IBIM, Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Cal, Italy
    Kidney Int 70:408-10. 2006
    ..It still remains to be tested whether clinical policies incorporating troponin T may actually produce better outcomes in PD patients...
  5. pmc Homoarginine and mortality in pre-dialysis chronic kidney disease (CKD) patients
    Pietro Ravani
    Department of Medicine and Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    PLoS ONE 8:e72694. 2013
    ....
  6. doi request reprint Uric acid, hypertension, and cardiovascular and renal complications
    Carmine Zoccali
    CNR National Research Council Italy Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension Unit and Nephrology, Hypertension and Renal Transplantation Unit, Ospedali Riuniti, Reggio Calabria, 89124, Italy
    Curr Hypertens Rep 15:531-7. 2013
    ..Evidence still remains largely insufficient to recommend changes in the current policy of not prescribing uric acid-lowering drugs to individuals with asymptomatic hyperuricemia. ..
  7. pmc Cultural adaptation and validation of the "Kidney Disease and Quality of Life--Short Form (KDQOL-SF™) version 1.3" questionnaire in Egypt
    Samar Abd Elhafeez
    Epidemiology Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt
    BMC Nephrol 13:170. 2012
    ..3 questionnaire in a representative series of Egyptian CKD patients...
  8. pmc Pro-inflammatory cytokines and bone fractures in CKD patients. An exploratory single centre study
    Vincenzo Panuccio
    Nephrology, Dialysis, Hypertension and Renal Transplantation Unit Azienda Ospedaliera, Via Vallone Petrara, 89124, Reggio Calabria, Italy
    BMC Nephrol 13:134. 2012
    ..We studied the relationship between inflammatory cytokines and incident bone fractures in a cohort of CKD-5D patients...
  9. doi request reprint FGF23: a mature renal and cardiovascular risk factor?
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation Division and CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Blood Purif 36:52-7. 2013
    ....
  10. pmc Pulmonary congestion predicts cardiac events and mortality in ESRD
    Carmine Zoccali
    National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Am Soc Nephrol 24:639-46. 2013
    ..015). In summary, lung ultrasound can detect asymptomatic pulmonary congestion in hemodialysis patients, and the resulting BL-US score is a strong, independent predictor of death and cardiac events in this population...
  11. doi request reprint Assessment of obesity in chronic kidney disease: what is the best measure?
    Carmine Zoccali
    Unita Operativa di Nefrologia, Dialisi e Trapianto Renale Ospedali Riunitiand IBIM CNR, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Reggio Calabria, Italy
    Curr Opin Nephrol Hypertens 21:641-6. 2012
    ..Obesity is a major driver of the current epidemic of chronic kidney disease (CKD), but metrics of obesity in the CKD population have been studied sparsely. This review updates knowledge on this issue...
  12. doi request reprint The fat-mass and obesity-associated gene (FTO) predicts mortality in chronic kidney disease of various severity
    Belinda Spoto
    CNR IBIM and Nephrology, Dialysis and Transplantation Unit of Reggio Calabria, Reggio Calabria, Italy
    Nephrol Dial Transplant 27:iv58-62. 2012
    ..Polymorphisms in the FTO (fat-mass and obesity-associated) gene have been associated with the body mass index, cancer, type 2 diabetes and hypertension...
  13. ncbi request reprint Dissecting inflammation in ESRD: do cytokines and C-reactive protein have a complementary prognostic value for mortality in dialysis patients?
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy
    J Am Soc Nephrol 17:S169-73. 2006
    ..IL-6 seems to be an almost ideal indicator of the severity of inflammation. The use of this biomarker can be recommended in clinical studies that aim to better the understanding of inflammation or to modify it in this population...
  14. doi request reprint Adiponectin and leptin in chronic kidney disease: causal factors or mere risk markers?
    Carmine Zoccali
    Unita Operativa di Nefrologia, Dialisi e Trapianto Renale Ospedali Riuniti and IBIM CNR, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Reggio Calabria, Italy
    J Ren Nutr 21:87-91. 2011
    ..However, LEP may exert noxious effects on the kidney (particularly renal fibrosis) if administered in conditions of LEP sufficiency or excess...
  15. doi request reprint Tissue inhibitor of metalloproteinases (TIMP-1), genetic markers of insulin resistance and cardiomyopathy in patients with kidney failure
    Belinda Spoto
    CNR IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Nephrology, Dialysis and Transplantation Unit of Reggio Calabria, Italy
    Nephrol Dial Transplant 27:2440-5. 2012
    ....
  16. doi request reprint Insulin resistance and left ventricular hypertrophy in end-stage renal disease: association between the ENPP1 gene and left ventricular concentric remodelling
    Belinda Spoto
    CNR IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Nephrology, Dialysis and Transplantation Unit, Reggio Calabria, Italy
    Nephrol Dial Transplant 27:661-6. 2012
    ..The ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) gene, whose variability has been repeatedly associated with IR, codes for a membrane glycoprotein which inhibits insulin-receptor signalling...
  17. ncbi request reprint Low triiodothyronine and survival in end-stage renal disease
    C Zoccali
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Division of Nephrology, Dialysis and Transplantation, Reggio Calabria, Italy
    Kidney Int 70:523-8. 2006
    ..Low fT3 is an independent predictor of death in hemodialysis patients. These data lend support to the hypothesis that thyroid dysfunction is implicated in the high risk of the ESRD population...
  18. ncbi request reprint Low triiodothyronine and cardiomyopathy in patients with end-stage renal disease
    Carmine Zoccali
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Reggio Calabria, Italy
    J Hypertens 24:2039-46. 2006
    ....
  19. ncbi request reprint Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism?
    C Zoccali
    Epidemiologia Clinica e Fisiopatologia delle malattie Renali e dell Ipertensione Arteriosae Unita Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy
    Kidney Int 70:2053-5. 2006
    ..These findings are of relevance for designing studies aimed at testing the etiologic relevance of ADMA to the high cardiovascular risk of ESRD...
  20. ncbi request reprint Clinical databases in nephrology: research and clinical practice goals and challenges
    Carmine Zoccali
    Unit of Nephrology, Dialysis and Renal Transplant, CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Ospedali Riuniti Reggio Calabria Italy
    J Nephrol 19:551-5. 2006
    ..Research on audit and feedback functionality is a new, useful and stimulating research area which may be of great interest to nephrologists...
  21. ncbi request reprint Chronic kidney disease epidemics--a gap in effectiveness: the distance between potential and actual treatment benefits
    Carmine Zoccali
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Nephrol 19:131-4. 2006
    ..Therefore, there is ample room for improving clinical outcomes in CKD by the systematic application of available treatments according to the recommendations of current clinical guidelines...
  22. ncbi request reprint Asymmetric dimethylarginine: a new player in the pathogenesis of renal disease?
    Carmine Zoccali
    Istituto di Biomedicina Epidemiologia Clinica e Fisiopatologia delle malattie Renali e dell Ipertensione Arteriosa e Unita Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy
    Curr Opin Nephrol Hypertens 15:314-20. 2006
    ..This review summarizes current knowledge on asymmetric dimethylarginine, renal function in health and disease, and renal disease progression and examines interventions that may modify the plasma concentration of this methylarginine...
  23. ncbi request reprint Left ventricular systolic function monitoring in asymptomatic dialysis patients: a prospective cohort study
    Carmine Zoccali
    National Research Council Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension of Reggio Calabria, Reggio Calabria, Italy
    J Am Soc Nephrol 17:1460-5. 2006
    ..02) than in those who had a decrease in mwFS. Changes in mwFS have an independent prognostic value for CV events, and periodic echocardiographic studies of systolic function are useful for monitoring asymptomatic dialysis patients...
  24. ncbi request reprint Inflammation as a mediator of the link between mild to moderate renal insufficiency and endothelial dysfunction in essential hypertension
    Carmine Zoccali
    Consiglio Nazionale delle Ricerche Instituto di Bio Medicina, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Ospedali Riuniti, 89124 Reggio Calabria, Italy
    J Am Soc Nephrol 17:S64-8. 2006
    ..The proatherogenic potential of inflammation associated with subtle impairment in renal function may contribute to the cardiovascular risk of essential hypertension...
  25. ncbi request reprint Urotensin II is an inverse predictor of incident cardiovascular events in end-stage renal disease
    C Zoccali
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Division of Nephrology, Dialysis and Transplantation, Reggio Calabria, Italy
    Kidney Int 69:1253-8. 2006
    ..UTN is an inverse predictor of CV outcomes in ESRD. Our data suggest that UTN should not be necessarily seen as a vasculotoxic peptide in haemodialysis patients...
  26. ncbi request reprint Renal impairment: a risk factor for ischemic heart disease
    Carmine Zoccali
    Department of Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal, Italy
    Curr Opin Pharmacol 6:221-5. 2006
    ....
  27. ncbi request reprint Mendelian randomization: a new approach to studying epidemiology in ESRD
    Carmine Zoccali
    Consiglio Nazionale delle Ricerche Istituto di Biomedicina, Clinical Epidemiology of Renal Diseases and Hypertension, Reggio Cal, Italy
    Am J Kidney Dis 47:332-41. 2006
    ..Examples are provided about the use of this concept to elucidate paradoxical inverse associations in epidemiological studies in the general and end-stage renal disease populations...
  28. ncbi request reprint Homocysteine and risk in end-stage renal disease: a matter of context
    C Zoccali
    Istituto di Biomedicina Epidemiologia e Fisiopatologia Clinica delle Malattie Renali e dell Ipertensione Arteriosa e Unità Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy
    Kidney Int 69:204-6. 2006
    ..A paper by Ducloux et al. in this issue adds perhaps decisive evidence on malnutrition-hypoalbuminemia as the main factor explaining the counterintuitive association between homocysteine and clinical outcome reported in previous studies...
  29. ncbi request reprint Asymmetric dimethyl-arginine (ADMA) response to inflammation in acute infections
    Carmine Zoccali
    CNR IBIM, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, c o Ki Point, Gransial SRL, Via Filippini n 85, 89100 Reggio Calabria, Italy
    Nephrol Dial Transplant 22:801-6. 2007
    ..We examined the evolution in the plasma concentration of ADMA measured at the clinical outset of acute inflammation and after its resolution in a series of 17 patients with acute bacterial infections...
  30. ncbi request reprint Prognostic value of the New York Heart Association classification in end-stage renal disease
    Maurizio Postorino
    CNR IBIM Istituto di Biomedicina Consiglio Nazionale delle Ricerche c o Divisione di Nefrologia e Dialisi Ospedali Riuniti 89100 Reggio Calabria, Italy
    Nephrol Dial Transplant 22:1377-82. 2007
    ....
  31. ncbi request reprint How important is echocardiography for risk stratification in follow-up of patients with chronic kidney disease?
    Carmine Zoccali
    Unit of Nephrology, Dialysis and Transplantation, and of the Section of Epidemiology and Pathophysiology of Renal Diseases and Hypertension, National Research Council, Reggio Calabria, Italy
    Nat Clin Pract Nephrol 3:178-9. 2007
  32. doi request reprint Urotensin II: a cardiovascular and renal update
    Carmine Zoccali
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Division of Nephrology, Dialysis and Transplantation, Reggio Calabria, Italy
    Curr Opin Nephrol Hypertens 17:199-204. 2008
    ..This review summarizes recent studies on cardiovascular and renal pathophysiology of urotensin II and clinical studies exploring the role of this peptide in cardiovascular and renal diseases...
  33. pmc ACE inhibition is renoprotective among obese patients with proteinuria
    Francesca Mallamaci
    CNR IBIM c o EUROLINE, di Ascrizzi Vincenzo, via Vallone Petrara 55 57, 89132 Reggio Calabria, Italy
    J Am Soc Nephrol 22:1122-8. 2011
    ..In summary, obesity predicts a higher incidence of renal events, but treatment with ramipril can essentially abolish this risk excess. Furthermore, the reduction in risk conferred by ramipril is larger among obese than nonobese patients...
  34. ncbi request reprint Cardiorenal risk as a new frontier of nephrology: research needs and areas for intervention
    Carmine Zoccali
    Division of Nephrology, Hypertension and Renal Transplantation, CNR Centro di Fisiologia Clinica, Reggio Calabria, Italy
    Nephrol Dial Transplant 17:50-4. 2002
    ..Observational studies aimed at linking these risk factors to well-defined and measured renal and cardiovascular outcomes should increase knowledge of renal disease progression and cardiovascular risk in these populations...
  35. doi request reprint Waist circumference modifies the relationship between the adipose tissue cytokines leptin and adiponectin and all-cause and cardiovascular mortality in haemodialysis patients
    C Zoccali
    Nephrology, Dialysis and Transplantation Unit and CNR IBIM Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Intern Med 269:172-81. 2011
    ....
  36. ncbi request reprint [Initiating dialysis early or late? New questions and new proposals]
    Carmine Zoccali
    Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e Ipertensione Arteriosa, Reggio Calabria, Italy
    G Ital Nefrol 27:584-7. 2010
    ..Both these intriguing proposals should be considered as a rational basis for new studies rather than as recommendations for clinical practice...
  37. doi request reprint What makes plaques vulnerable in CKD?: a fresh look at metalloproteinases
    Carmine Zoccali
    Department of Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Kidney Int 78:1206-8. 2010
    ..Future studies should look at the association of MMPs (and their inhibitors) with the inflammatory component of atherosclerosis, and with stable and unstable atherosclerotic lesions...
  38. doi request reprint The databases: renal replacement therapy since 1989--the European Renal Association and European Dialysis and Transplant Association (ERA-EDTA)
    Carmine Zoccali
    Nephrology and Renal Transplantation Unit and Consiglio Nazionale delle Ricerche, Instituto di Biomedicina, Ospedali Riuniti, Reggio Cal, Italy
    Clin J Am Soc Nephrol 4:S18-22. 2009
    ..In this respect, Dialysis Outcomes and Practice Patterns Study Europe has revealed relevant differences in clinical policies that are related to ESRD treatment among European countries...
  39. doi request reprint The burden of cardiovascular disease in patients with chronic kidney disease and in end-stage renal disease
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Contrib Nephrol 161:63-7. 2008
    ..Multiple interventions on the multiple, modifiable risk factors of CKD at population and hospital level should be deployed if we are to curb the burden of CV sequelae of the CKD epidemics...
  40. ncbi request reprint Cardiovascular risk in patients with chronic kidney disease: not high enough to enter the major league?
    Carmine Zoccali
    Unità Operativa di Nefrologia Dialisi e Trapianto Renale e Ipertensione Arteriosa, Ospedali Riuniti 89124 Reggio Calabria, Italy
    Curr Hypertens Rep 10:1-2. 2008
  41. ncbi request reprint The MAURO study: multiple intervention and audit in renal diseases to optimize care
    Carmine Zoccali
    CNR IBIM, National Research Council Institute of Biomedicine, Reggio Calabria, Italy
    J Nephrol 21:20-2. 2008
  42. ncbi request reprint Urotensin II and cardiomyopathy in end-stage renal disease
    Carmine Zoccali
    Consiglio Nationale delle Ricerche CNR Istituto di Biomedicina IBIM, Division of Nephrology, Dialysis and Transplantation, Reggio Calabria, Italy
    Hypertension 51:326-33. 2008
    ..Additional mechanistic insights may be needed before launching long-term clinical trials with UTN antagonists in patients with end-stage renal disease...
  43. ncbi request reprint The endothelium as a target in renal diseases
    Carmine Zoccali
    CNR IBIM, National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria Italy
    J Nephrol 20:S39-44. 2007
    ....
  44. ncbi request reprint It is important to lower homocysteine in dialysis patients
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation Unit, CNR IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Semin Dial 20:530-3. 2007
    ..The contention that the homocysteine pathway cannot be used for interventions aimed at curbing cardiovascular risk in this population is, at least by now, unwarranted...
  45. ncbi request reprint [The chronic renal failure epidemic: an underestimated public health problem]
    C Zoccali
    UO di Nefrologia, Dialisi e Trapianto CNR IBIM, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Ospedali Riuniti, Reggio Calabria, Italy
    G Ital Nefrol 24:3-7. 2007
    ....
  46. ncbi request reprint Cardiovascular risk profile assessment and medication control should come first
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Ospedali Riuniti, Reggio Calabria, Italy
    Semin Dial 20:405-8. 2007
  47. pmc Phosphate may promote CKD progression and attenuate renoprotective effect of ACE inhibition
    Carmine Zoccali
    Nephrology, Dialysis and Transplantation Unit, Ospedali Riuniti, Reggio Calabria, Italy
    J Am Soc Nephrol 22:1923-30. 2011
    ..Future trials should test whether reducing serum phosphate improves renal outcomes and optimizes the renoprotective effect of ACE inhibition...
  48. ncbi request reprint The importance of large, high quality clinical databases in nephrology
    C Zoccali
    CNR Centre of Clinical Physiology and Division of Nephrology, Reggio Calabria, Italy
    J Nephrol 14:S89-93. 2001
    ..The task may be daunting but worth while; due to complexity and cost the randomised clinical trial is unlikely to remain the only source of information on which to base clinical decisions about treatments...
  49. ncbi request reprint Fibrinogen, inflammation and concentric left ventricular hypertrophy in chronic renal failure
    C Zoccali
    Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, c o Ospedali Riuniti Bianchi Melacrino Morelli Via Vallone Petrara, 89124 Reggio Calabria, Italy
    Eur J Clin Invest 33:561-6. 2003
    ..We investigated the relationship between fibrinogen and echocardiographic measurements of left ventricular (LV) geometry and LV function in a group of 192 patients with end stage renal disease (ESRD)...
  50. ncbi request reprint Neuropeptide Y, left ventricular mass and function in patients with end stage renal disease
    Carmine Zoccali
    CNR, Institute of Biomedicine, Epidemiology and Pathophysiology of Renal Diseases and Hypertension and Division of Nephrology, Morelli Hospital, Reggio Calabria, Italy
    J Hypertens 21:1355-62. 2003
    ....
  51. ncbi request reprint Chlamydia pneumoniae, overall and cardiovascular mortality in end-stage renal disease (ESRD)
    Carmine Zoccali
    National Research Council CNR, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Kidney Int 64:579-84. 2003
    ..Cross-sectional and retrospective studies suggest that Chlamydia pneumoniae infection may contribute importantly to the high cardiovascular risk of patients with end-stage renal disease (ESRD)...
  52. ncbi request reprint Fibrinogen, mortality and incident cardiovascular complications in end-stage renal failure
    C Zoccali
    National Research Council, Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Cal, Italy
    J Intern Med 254:132-9. 2003
    ....
  53. ncbi request reprint Prospective study of neuropeptide y as an adverse cardiovascular risk factor in end-stage renal disease
    Carmine Zoccali
    CNR IBIM, Institute of Biomedicine, Epidemiology, and Pathophysiology of Renal Diseases and Hypertension, and Division of Nephrology, Morelli Hospital, Reggio Calabria, Italy
    J Am Soc Nephrol 14:2611-7. 2003
    ..Controlled trials are needed to establish whether interference with the sympathetic system, NPY, or both may reduce the high CV morbidity and mortality of dialysis patients...
  54. ncbi request reprint Novel cardiovascular risk factors in end-stage renal disease
    Carmine Zoccali
    CNR IBIM, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Reggio Calabria, Italy
    J Am Soc Nephrol 15:S77-80. 2004
    ..ADMA per se seems responsible for a 52% increase in the risk of death and for a 34% increase in the risk of cardiovascular events in dialysis patients...
  55. ncbi request reprint Prognostic value of echocardiographic indicators of left ventricular systolic function in asymptomatic dialysis patients
    Carmine Zoccali
    CNR IBIM National Research Council, Institute of Biomedicine, Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Ospedali Riuniti Via Vallone Petrara, 89124 Reggio Calabria, Italy
    J Am Soc Nephrol 15:1029-37. 2004
    ..Risk stratification by simple systolic function parameters may prove useful in secondary prevention strategies in these patients...
  56. ncbi request reprint Left ventricular mass monitoring in the follow-up of dialysis patients: prognostic value of left ventricular hypertrophy progression
    Carmine Zoccali
    Institute of Biomedicine Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Kidney Int 65:1492-8. 2004
    ..Whether changes in left ventricular mass (LVM) in clinical practice predict survival and cardiovascular events in these patients is still unknown...
  57. ncbi request reprint ADMA: a critical cardio-renal link in heart failure?
    C Zoccali
    IBIM CNR, Epidemiologia Clinica and Fisiopatologia delle Malattie Renali and dell Ipertensione Arteriosa, Reggio Cal, Italy
    Eur J Clin Invest 33:361-2. 2003
  58. ncbi request reprint Another Marker of Cardiac Dysfunction in Dialysis Patients?
    Carmine Zoccali
    Istituto CNR di Biomedicina, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Reggio Calabria, Italy
    Nephron Clin Pract 93:C49-50. 2003
  59. ncbi request reprint Inflammation and atherosclerosis in end-stage renal disease
    Carmine Zoccali
    Consiglio Nazionale delle Ricerche CNR IBM, Laboratorio CNR di Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Ospedali Riuniti, Reggio Calabria, Italia
    Blood Purif 21:29-36. 2003
    ..The intellectual framework is well delineated but very few controlled trials have been performed or are underway in patients with ESRD...
  60. ncbi request reprint Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease
    Carmine Zoccali
    CNR Centre of Clinical Physiology and Renal Unit, Morelli Hospital, Reggio, Calabria, Italy
    J Am Soc Nephrol 13:490-6. 2002
    ..These data support the hypothesis that accumulation of this endogenous inhibitor of NO synthase is an important risk factor for cardiovascular disease in chronic renal failure and suggest a possible link between ADMA and inflammation...
  61. ncbi request reprint Nocturnal hypoxemia predicts incident cardiovascular complications in dialysis patients
    Carmine Zoccali
    CNR, Centre of Clinical Physiology and Division of Nephrology, Ospedali Riuniti, Reggio Calabria, Italy
    J Am Soc Nephrol 13:729-33. 2002
    ..61 to 15.86) than in those above this threshold (P = 0.005). This study adds weight to the hypothesis that nocturnal hypoxemia in dialysis patients represents an important cardiovascular risk factor...
  62. ncbi request reprint Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease
    Carmine Zoccali
    CNR, Centre of Clinical Physiology and Division of Nephrology, Reggio Calabria, Italy
    Circulation 105:1354-9. 2002
    ....
  63. ncbi request reprint Hypertension in end-stage renal disease: target values, methods of measurement and drug therapy
    Carmine Zoccali
    Clinical Physiology Center of the National Research Council, Unit of Nephrology, Dialysis and Transplantation, RC Hospital, Reggio Calabria, Italy
    J Nephrol 15:199-201. 2002
  64. ncbi request reprint Norepinephrine and concentric hypertrophy in patients with end-stage renal disease
    Carmine Zoccali
    CNR, Centre of Clinical Physiology and Division of Nephrology, Reggio Calabria, Italy
    Hypertension 40:41-6. 2002
    ..003). Plasma NE is associated to concentric LVH in ESRD patients. These observations constitute a sound basis for testing the effect of anti-adrenergic drugs on left ventricle mass and on cardiovascular outcomes in patients with ESRD...
  65. ncbi request reprint Hypertension as a cardiovascular risk factor in end-stage renal failure
    Carmine Zoccali
    CNR Centro di Fisiologia Clinica, Ospedali Riuniti, Via Vallone Petrara, 89124 Regio Cal, Italy
    Curr Hypertens Rep 4:381-6. 2002
    ....
  66. ncbi request reprint Prognostic impact of the indexation of left ventricular mass in patients undergoing dialysis
    C Zoccali
    Centre of Clinical Physiology and Division of Nephrology, Morelli Hospital, Reggio Cal, Italy
    J Am Soc Nephrol 12:2768-74. 2001
    ..The indexing of LVM by height(2.7) provides more powerful prediction of mortality and cardiovascular outcomes than the BSA-based method, and the use of this index appears to be appropriate in patients undergoing dialysis...
  67. ncbi request reprint Atherosclerotic renal artery stenosis: epidemiology, cardiovascular outcomes, and clinical prediction rules
    Carmine Zoccali
    Unità Opertativa di Nefrologia, Dialisi e Trapianto, Reggio Calabria, Italy
    J Am Soc Nephrol 13:S179-83. 2002
    ..When tested in a systematic and quantitative manner, clinical findings can perform as accurately as more complex tests in the detection of renal artery stenosis...
  68. ncbi request reprint Cardiac consequences of hypertension in hemodialysis patients
    Carmine Zoccali
    Istituto di Biomedicina Epidemiologia Clinica e Fisiopatologia delle malattie Renali e dell Ipertensione Arteriosa e Unita Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy
    Semin Dial 17:299-303. 2004
    ..Despite the lack of evidence from randomized controlled trials, it appears reasonable that interventions aimed at curbing the high CV mortality of ESRD should be targeted to both hypertension and LVH...
  69. ncbi request reprint Inflammatory proteins as predictors of cardiovascular disease in patients with end-stage renal disease
    Carmine Zoccali
    CNR IBIM, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Unita Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti VI piano, 89125 Reggio Calabria, Italy
    Nephrol Dial Transplant 19:V67-72. 2004
    ..Furthermore, ADPN is related to several metabolic risk factors in a manner consistent with the hypothesis that this protein acts as a protective factor for the cardiovascular system...
  70. ncbi request reprint Low triiodothyronine: a new facet of inflammation in end-stage renal disease
    Carmine Zoccali
    CNR IBIM, Clinical Epidemiology and Pathosphysiology of Renal Diseases and Hypertension, Ospedali Riuniti, Calabria, Italy
    J Am Soc Nephrol 16:2789-95. 2005
    ..This association may entail a causal link because fT3 is acutely and reversibly suppressed in patients with CKD during inflammatory processes triggered by intercurrent infections...
  71. ncbi request reprint Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients
    Carmine Zoccali
    CNR, Division of Nephrology, Centre of Clinical Physiology and Renal Unit, Via Sbarre Inferiori 39, 89131 Reggio Calabria, Italy
    Kidney Int 62:339-45. 2002
    ..The endogenous inhibitor of nitric oxide (NO), asymmetric dimethylarginine (ADMA), is a strong predictor of adverse cardiovascular outcomes in patients with end-stage renal disease (ESRD)...
  72. ncbi request reprint Biomarkers in chronic kidney disease: utility and issues towards better understanding
    Carmine Zoccali
    Nephrology, Hypertension and Renal Transplantation, CNR IBIM Clinical Epidemiology of Renal Diseases and Hypertension, Riuniti Hospital, Reggio Cal, Italy
    Curr Opin Nephrol Hypertens 14:532-7. 2005
    ..This review examines the value of a series of biomarkers which have been recently tested in prospective studies in chronic kidney disease and end-stage renal disease patients...
  73. ncbi request reprint Neuropeptide Y as a far-reaching neuromediator: from energy balance and cardiovascular regulation to central integration of weight and bone mass control mechanisms. Implications for human diseases
    Carmine Zoccali
    CNR IBIM Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Ospedali Riuniti, Reggio Calabria, Italy
    Curr Opin Nephrol Hypertens 14:25-32. 2005
    ..I review recent knowledge on the interference of neuropeptide Y with energy balance and cardiovascular and renal disease and on the central regulation of bone mass...
  74. ncbi request reprint Clinical epidemiology of major nontraditional risk factors in peritoneal dialysis patients
    Carmine Zoccali
    CNR IBIM Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Ospedali Riuniti, Calabria, Italy
    Perit Dial Int 25:S84-7. 2005
    ..While traditional risk factors dominate the scene in the general population, in chronic kidney disease (CKD), nontraditional risk factors play an increasingly important role, being perhaps dominant in ESRD patients...
  75. ncbi request reprint Leptin and biochemical markers of bone turnover in dialysis patients
    Carmine Zoccali
    CNR IBIM, National Research Council Institute of Biomedicine Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    J Nephrol 17:253-60. 2004
    ..We studied the relationship between plasma leptin and biochemical bone turnover indicators in 161 hemodialysis (HD) patients...
  76. doi request reprint Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension
    Francesco Perticone
    Department of Experimental and Clinical Medicine, G Salvatore, University Magna Graecia of Catanzaro, Reggio Calabria, Italy
    Am J Kidney Dis 52:74-84. 2008
    ..Left ventricular (LV) hypertrophy and decreased kidney function are well-established cardiovascular risk factors in hypertensive patients...
  77. ncbi request reprint Urotensin II in end-stage renal disease: an inverse correlate of sympathetic function and cardiac natriuretic peptides
    Francesca Mallamaci
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Dialysis and Transplantation, Reggio Calabria Italy
    J Nephrol 18:727-32. 2005
    ..Urotensin II (UTN) is a peptide highly conserved across species with disparate effects on the vascular system and it is currently unclear whether high plasma UTN levels play a vasculotoxic or a vasculoprotective role...
  78. doi request reprint Biomarkers of left atrial volume: a longitudinal study in patients with end stage renal disease
    Giovanni Tripepi
    CNR IBIM, Istituto di Biomedicina, Epidemiologia Clinica e Fisiopatologia, delle Malattie Renali e dell Ipertensione Arteriosa, c o EUROLINE di Ascrizzi Vincenzo, via Vallone Petrara 55 57, Reggio Calabria, Italy
    Hypertension 54:818-24. 2009
    ....
  79. ncbi request reprint Troponin is related to left ventricular mass and predicts all-cause and cardiovascular mortality in hemodialysis patients
    Francesca Mallamaci
    Divisione di Nefrologia e CNR, Centro di Fisiologia Clinica, Reggio Calabria, Italy
    Am J Kidney Dis 40:68-75. 2002
    ..These data support the hypothesis that this marker can be usefully applied for risk stratification in clinically stable dialysis patients...
  80. ncbi request reprint Adiponectin in essential hypertension
    Francesca Mallamaci
    CNR, Center of Clinical Physiology, Reggio Calabria, Italy
    J Nephrol 15:507-11. 2002
    ..High levels in essential hypertensives may be the expression of a counter-regulatory response aimed at mitigating endothelial damage and cardiovascular risk associated with high arterial pressure...
  81. ncbi request reprint Prognostic value of 24-hour ambulatory blood pressure monitoring and of night/day ratio in nondiabetic, cardiovascular events-free hemodialysis patients
    Giovanni Tripepi
    CNR IBIM, Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension, Reggio Cal, Italy
    Kidney Int 68:1294-302. 2005
    ....
  82. ncbi request reprint Diagnostic value of troponin T for alterations in left ventricular mass and function in dialysis patients
    Francesca Mallamaci
    CNR Centre of Clinical Physiology and Division of Nephrology, Reggio Calabria, Italy
    Kidney Int 62:1884-90. 2002
    ..We tested the diagnostic value of cTnT for left ventricular hypertrophy (LVH) and LV systolic dysfunction in a large group of clinically stable hemodialysis patients without heart failure...
  83. ncbi request reprint Subclinical hypothyroidism is linked to micro-inflammation and predicts death in continuous ambulatory peritoneal dialysis
    Giuseppe Enia
    CNR IBIM, Istituto di Biomedicina, Epidemiologia Clinica e Fisiopatologia, delle Malattie Renali e dell Ipertensione Arteriosa, c o Ki Point Gransial Srl, Via Filippini n 85, 89125 Reggio Calabria, Italy
    Nephrol Dial Transplant 22:538-44. 2007
    ..Low T3 is a frequent alteration in patients with ESRD. This derangement has been recently linked to inflammation in haemodialysis patients. Whether this association holds true in peritoneal dialysis patients has not been studied...
  84. ncbi request reprint Prognostic value of combined use of biomarkers of inflammation, endothelial dysfunction, and myocardiopathy in patients with ESRD
    Francesca Mallamaci
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Reggio Calabria, Italy
    Kidney Int 67:2330-7. 2005
    ..Cardiovascular risk stratification is important in the clinical management of patients with end-stage renal diseases (ESRD) and biomarkers are increasingly used in these patients...
  85. ncbi request reprint Neuropeptide Y and markers of osteoblast activity in dialysis patients: a cross-sectional study
    Vincenzo Panuccio
    CNR IBIM, National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Am J Kidney Dis 50:1001-8. 2007
    ..In mice, neuropeptide Y (NPY) decreases bone turnover by means of a parathyroid hormone-independent effect on osteoblast activity...
  86. ncbi request reprint Vascular endothelial growth factor, left ventricular dysfunction and mortality in hemodialysis patients
    Francesca Mallamaci
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension, Reggio Calabria, Italy
    J Hypertens 26:1875-82. 2008
    ..We investigated the relationship between vascular endothelial growth factor, left ventricular function (by midwall fractional shortening) and mortality in a prospective cohort study in 228 hemodialysis patients...
  87. ncbi request reprint Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients
    Francesca Mallamaci
    CNR Centro Fisiologia Clinica e Divisione di Nefrologia, Ospedali Riuniti, Reggio Calabria, Italy
    Kidney Int 61:609-14. 2002
    ..We prospectively tested the prediction power of homocysteinemia for all-cause and cardiovascular outcomes in a cohort of 175 hemodialysis patients followed for 29 +/- 12 months...
  88. doi request reprint Vitamin D receptor (VDR) gene polymorphism is associated with left ventricular (LV) mass and predicts left ventricular hypertrophy (LVH) progression in end-stage renal disease (ESRD) patients
    Alessandra Testa
    CNR IBIM, Research Unit of Clinical Epidemiology and Physiopathology of Renal Disease and Hypertension, Reggio Calabria, Italy
    J Bone Miner Res 25:313-9. 2010
    ..These cross-sectional and longitudinal observations coherently support the hypothesis that altered vitamin D signaling is implicated in LVH in ESRD patients...
  89. ncbi request reprint Urotensin II and biomarkers of endothelial activation and atherosclerosis in end-stage renal disease
    Francesca Mallamaci
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Dialysis and Transplantation, Reggio Calabria, Italy
    Am J Hypertens 19:505-10. 2006
    ..Because UTN accumulates in patients with chronic renal failure, the association between plasma UTN and biomarkers of atherosclerosis and endothelial activation needs to be better understood...
  90. ncbi request reprint Heart valve calcifications, survival, and cardiovascular risk in hemodialysis patients
    Vincenzo Panuccio
    National Research Council, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Am J Kidney Dis 43:479-84. 2004
    ..The prognostic value of cardiac valve calcifications and their relationship with left ventricular hypertrophy and background cardiovascular risk in hemodialysis patients is still unknown...
  91. ncbi request reprint Uric acid and endothelial dysfunction in essential hypertension
    Carmine Zoccali
    CNR IBIM Consiglio Nazionale delle Ricerche, Istituto di Biomedicina, delle Malattie Renali e dell Ipertensione Arteriosa, c o Divisione di Nefrologia e Dialisi, Ospedali Riuniti Via Vallone Petrara, Reggio Calabria, Italy
    J Am Soc Nephrol 17:1466-71. 2006
    ..Probably, the chronic inflammation that was documented in these patients may be considered the mechanistic link between serum UA and vascular damage...
  92. ncbi request reprint Hyperhomocysteinemia and arteriovenous fistula thrombosis in hemodialysis patients
    Francesca Mallamaci
    Division of Nephrology, Consiglio Nazionale della Ricerche Istituto di Bio Medicina, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Am J Kidney Dis 45:702-7. 2005
    ....
  93. ncbi request reprint An additive effect of endothelial nitric oxide synthase gene polymorphisms contributes to the severity of atherosclerosis in patients on dialysis
    Belinda Spoto
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Reggio Calabria, Italy
    Am J Hypertens 20:758-63. 2007
    ..Reduced synthesis of nitric oxide (NO) is considered a major proatherogenic mechanism in patients with end-stage renal disease (ESRD), but genetic factors impinging on this mechanism have been little studied in this population...
  94. ncbi request reprint Fibrinogen and calcium x phosphate product are predictors of cardiovascular events in the CAPD population
    Giuseppe Enia
    CNR IBIM, Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension and Division of Nephrology, Reggio Calabria Italy
    J Nephrol 18:764-9. 2005
    ..Plasma fibrinogen (Fib) and calcium x phosphate product have emerged as cardiovascular (CV) event predictors in hemodialysis (HD) patients, but their role in peritoneal dialysis (PD) is less studied...
  95. ncbi request reprint Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease
    Belinda Spoto
    CNR IBIM, National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio, Calabria, Italy
    Am J Hypertens 18:1549-55. 2005
    ....
  96. ncbi request reprint Detection of pulmonary congestion by chest ultrasound in dialysis patients
    Francesca Mallamaci
    Nephrology and Renal Transplantation Unit Ospedali Riuniti, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    JACC Cardiovasc Imaging 3:586-94. 2010
    ..This study sought to investigate clinical and echocardiographic correlates of the lung comets score...
  97. ncbi request reprint The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease
    Alessandra Testa
    CNR IBIM, National Research Council Institute of Biomedicine, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria and Department of Internal Medicine, Catania University, Catania, Italy
    J Hypertens 23:1825-30. 2005
    ..We evaluated the role of endothelial NOS (eNOS) gene polymorphisms and its interaction with plasma ADMA in the high cardiovascular complications rate of these patients...
  98. doi request reprint Clinical implications of elevated asymmetric dimethylarginine in chronic kidney disease and end-stage renal disease
    Francesca Mallamaci
    Renal and Transplantation Unit, Ospedali Riuniti, and CNR IBIM, Reggio Cal, Iitaly
    J Ren Nutr 19:25-8. 2009
    ....
  99. doi request reprint Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients
    Giovanni Tripepi
    CNR IBIM, Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Reggio Calabria, Italy
    Clin J Am Soc Nephrol 6:1714-21. 2011
    ..Inflammation amplifies the effect of ADMA on the severity of atherosclerosis in ESRD patients, but it is still unknown whether inflammation and ADMA interact in the high risk of death and CV events in this population...
  100. ncbi request reprint Adipose tissue cytokines, insulin sensitivity, inflammation, and cardiovascular outcomes in end-stage renal disease patients
    Carmine Zoccali
    Consiglio Nazionale Ricerche Istituto BIo Medicina Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa, Reggio Calabria, Italy
    J Ren Nutr 15:125-30. 2005
    ..Finally, low adiponectin and high norepinephrine seem to be interacting factors in the dismal cardiovascular outcomes with ESRD...
  101. ncbi request reprint Predictors of cardiovascular death in ESRD
    Carmine Zoccali
    CNR IBIM Istituto di Biomedicina, Epidemiologia Clinica e Fisiopatologia delle Malattie Renali e dell Ipertensione Arteriosa e Unità Operativa di Nefrologia, Dialisi e Trapianto Renale, Ospedali Riuniti, Reggio Calabria, Italy
    Semin Nephrol 25:358-62. 2005
    ..Biomarkers give information beyond that provided by traditional risk factors and therefore represent an useful adjunct for the definition of the risk profile of ESRD patients...