M M Zanone

Summary

Country: Italy

Publications

  1. doi request reprint Human mesenchymal stem cells modulate cellular immune response to islet antigen glutamic acid decarboxylase in type 1 diabetes
    Maria M Zanone
    Department of Internal Medicine, University of Turin, Turin, Italy
    J Clin Endocrinol Metab 95:3788-97. 2010
  2. pmc The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalli
    E Favaro
    Department of Internal Medicine, University of Turin, Turin, Italy
    Diabetologia 55:1058-70. 2012
  3. doi request reprint Association of autoimmunity to autonomic nervous structures with nerve function in patients with type 1 diabetes: a 16-year prospective study
    Maria M Zanone
    Corresponding author Maria M Zanone
    Diabetes Care 37:1108-15. 2014
  4. doi request reprint Association of cytomegalovirus infections with recurrence of humoral and cellular autoimmunity to islet autoantigens and of type 1 diabetes in a pancreas transplanted patient
    Maria M Zanone
    Department of Internal Medicine, University of Turin, Turin, Italy
    Transpl Int 23:333-7. 2010
  5. ncbi request reprint Human pancreatic islet endothelial cells express coxsackievirus and adenovirus receptor and are activated by coxsackie B virus infection
    Maria M Zanone
    Department of Internal Medicine, University of Torino, Italy
    FASEB J 21:3308-17. 2007
  6. ncbi request reprint Expression of nephrin by human pancreatic islet endothelial cells
    M M Zanone
    Department of Internal Medicine and Centre of Experimental Medicine CeRMS, University of Torino, Corso Dogliotti 14, Torino, Italy
    Diabetologia 48:1789-97. 2005
  7. ncbi request reprint Persistent infection of human microvascular endothelial cells by coxsackie B viruses induces increased expression of adhesion molecules
    Maria M Zanone
    Department of Internal Medicine and Center of Experimental Medicine CeRMS, University of Torino, Torino, Italy
    J Immunol 171:438-46. 2003
  8. ncbi request reprint Autonomic function and autoantibodies to autonomic nervous tissues at follow-up in a cohort of young patients with type 1 diabetes. Effects of serum from diabetic patients on human adrenergic cells
    Maria M Zanone
    Department of Internal Medicine, Research Center for Experimental Medicine, University of Torino, Corso Dogliotti 14, 10126, Torino, Italy
    J Neuroimmunol 139:66-75. 2003
  9. ncbi request reprint Primary and immortalised human pancreatic islet endothelial cells: phenotypic and immunological characterisation
    E Favaro
    Department of Internal Medicine and Center of Experimental Medicine CeRMS, University of Turin, Turin, Italy
    Diabetologia 48:2552-62. 2005
  10. ncbi request reprint Glutamic acid decarboxylase and ICA512/IA-2 autoantibodies as disease markers and relationship to residual beta-cell function and glycemic control in young type 1 diabetic patients
    M M Zanone
    Division of Internal Medicine, University of Torino, Torino, Italy
    Metabolism 52:25-9. 2003

Collaborators

Detail Information

Publications14

  1. doi request reprint Human mesenchymal stem cells modulate cellular immune response to islet antigen glutamic acid decarboxylase in type 1 diabetes
    Maria M Zanone
    Department of Internal Medicine, University of Turin, Turin, Italy
    J Clin Endocrinol Metab 95:3788-97. 2010
    ..Mesenchymal stem cells (MSCs) exert an immunosuppressive effect on the immune system. However, studies on the immunomodulatory potential of MSCs in type 1 diabetes are lacking...
  2. pmc The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalli
    E Favaro
    Department of Internal Medicine, University of Turin, Turin, Italy
    Diabetologia 55:1058-70. 2012
    ..We investigated whether the ghrelin gene products and the GLP-1 receptor agonist exendin-4 (Ex-4) display survival effects in human pancreatic islet microendothelial cells (MECs) exposed to chronic hyperglycaemia...
  3. doi request reprint Association of autoimmunity to autonomic nervous structures with nerve function in patients with type 1 diabetes: a 16-year prospective study
    Maria M Zanone
    Corresponding author Maria M Zanone
    Diabetes Care 37:1108-15. 2014
    ..CONCLUSIONS Circulating Ab to autonomic structures are associated with the development of autonomic dysfunction in young diabetic patients independent of glycemic control. ..
  4. doi request reprint Association of cytomegalovirus infections with recurrence of humoral and cellular autoimmunity to islet autoantigens and of type 1 diabetes in a pancreas transplanted patient
    Maria M Zanone
    Department of Internal Medicine, University of Turin, Turin, Italy
    Transpl Int 23:333-7. 2010
    ....
  5. ncbi request reprint Human pancreatic islet endothelial cells express coxsackievirus and adenovirus receptor and are activated by coxsackie B virus infection
    Maria M Zanone
    Department of Internal Medicine, University of Torino, Italy
    FASEB J 21:3308-17. 2007
    ....
  6. ncbi request reprint Expression of nephrin by human pancreatic islet endothelial cells
    M M Zanone
    Department of Internal Medicine and Centre of Experimental Medicine CeRMS, University of Torino, Corso Dogliotti 14, Torino, Italy
    Diabetologia 48:1789-97. 2005
    ..In this study, we purified and characterised microvascular endothelial cells (MECs) isolated from human islets and investigated the expression and distribution of nephrin on these cells...
  7. ncbi request reprint Persistent infection of human microvascular endothelial cells by coxsackie B viruses induces increased expression of adhesion molecules
    Maria M Zanone
    Department of Internal Medicine and Center of Experimental Medicine CeRMS, University of Torino, Torino, Italy
    J Immunol 171:438-46. 2003
    ..Furthermore, our data confirm that the behavior against a viral challenge of ECs in large vessels and microvessels may differ...
  8. ncbi request reprint Autonomic function and autoantibodies to autonomic nervous tissues at follow-up in a cohort of young patients with type 1 diabetes. Effects of serum from diabetic patients on human adrenergic cells
    Maria M Zanone
    Department of Internal Medicine, Research Center for Experimental Medicine, University of Torino, Corso Dogliotti 14, 10126, Torino, Italy
    J Neuroimmunol 139:66-75. 2003
    ....
  9. ncbi request reprint Primary and immortalised human pancreatic islet endothelial cells: phenotypic and immunological characterisation
    E Favaro
    Department of Internal Medicine and Center of Experimental Medicine CeRMS, University of Turin, Turin, Italy
    Diabetologia 48:2552-62. 2005
    ..We aimed to morphologically and functionally characterise primary MECs purified and cultured from human islets, and to establish a simian virus 40 (SV40)-immortalised cell line from these primary cultures...
  10. ncbi request reprint Glutamic acid decarboxylase and ICA512/IA-2 autoantibodies as disease markers and relationship to residual beta-cell function and glycemic control in young type 1 diabetic patients
    M M Zanone
    Division of Internal Medicine, University of Torino, Torino, Italy
    Metabolism 52:25-9. 2003
    ....
  11. ncbi request reprint Autonomic function and autoantibodies to autonomic nervous structures, glutamic acid decarboxylase and islet tyrosine phosphatase in adolescent patients with IDDM
    M M Zanone
    Division of Internal Medicine, University of Turin, Italy
    J Neuroimmunol 87:1-10. 1998
    ....
  12. ncbi request reprint From endothelial to beta cells: insights into pancreatic islet microendothelium
    Maria M Zanone
    Department of Internal Medicine, University of Torino, Torino, Italy
    Curr Diabetes Rev 4:1-9. 2008
    ..In this review we will describe the phenotypic and functional characteristics of islet microendothelium and its possible involvement in type 1 and 2 diabetes, and islet revascularisation in transplantation settings...
  13. ncbi request reprint Anti-CD38 autoantibodies: characterisation in new-onset type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies
    R Mallone
    Department of Internal Medicine, University of Torino, Italy
    Diabetologia 45:1667-77. 2002
    ..Whether these aAbs are also found in new-onset Type I diabetes and in Latent Autoimmune Diabetes in Adults (LADA) is not known, as is their relationship with conventional islet aAbs...
  14. pmc Hyperglycemia induces apoptosis of human pancreatic islet endothelial cells: effects of pravastatin on the Akt survival pathway
    Enrica Favaro
    Department of Internal Medicine, University of Torino, Torino, Italy
    Am J Pathol 173:442-50. 2008
    ....