G Zaccara

Summary

Country: Italy

Publications

  1. ncbi Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies?
    G Zaccara
    Unit of Neurology, S M Nuova Hospital, Florence, Italy
    Acta Neurol Scand 114:157-68. 2006
  2. doi The adverse event profile of pregabalin across different disorders: a meta-analysis
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Florence, Italy
    Eur J Clin Pharmacol 68:903-12. 2012
  3. doi The adverse event profile of perampanel: meta-analysis of randomized controlled trials
    G Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Eur J Neurol 20:1204-11. 2013
  4. doi Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Firenze, Italy
    Seizure 22:528-36. 2013
  5. doi AMPA receptor inhibitors for the treatment of epilepsy: the role of perampanel
    Gaetano Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Expert Rev Neurother 13:647-55. 2013
  6. doi The adverse event profile of lacosamide: a systematic review and meta-analysis of randomized controlled trials
    Gaetano Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Epilepsia 54:66-74. 2013
  7. doi Central nervous system adverse effects of new antiepileptic drugs. A meta-analysis of placebo-controlled studies
    G Zaccara
    Unit of Neurology, Piero Palagi Hospital, Viale Michelangelo 41, Florence, Firenze, Italy
    Seizure 17:405-21. 2008
  8. doi Neurological comorbidity and epilepsy: implications for treatment
    G Zaccara
    Unit of Neurology, Palagi Hospital, Viale Michelangelo 41, Florence, Italy
    Acta Neurol Scand 120:1-15. 2009
  9. doi The adverse event profile of pregabalin: a systematic review and meta-analysis of randomized controlled trials
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Firenze, Italy
    Epilepsia 52:826-36. 2011
  10. doi Drug safety evaluation of zonisamide for the treatment of epilepsy
    Gaetano Zaccara
    Giovanni Di Dio Hospital, Unit of Neurology, Firenze, Italy
    Expert Opin Drug Saf 10:623-31. 2011

Detail Information

Publications24

  1. ncbi Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies?
    G Zaccara
    Unit of Neurology, S M Nuova Hospital, Florence, Italy
    Acta Neurol Scand 114:157-68. 2006
    ..A review of long-term open-label studies was performed with the aim of detecting differences in efficacy and/or tolerability of new antiepileptic drugs (AEDs)...
  2. doi The adverse event profile of pregabalin across different disorders: a meta-analysis
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Florence, Italy
    Eur J Clin Pharmacol 68:903-12. 2012
    ..In the present study, we evaluated whether the incidence of these 20 AEs differs across distinct disorders in which PGB was investigated...
  3. doi The adverse event profile of perampanel: meta-analysis of randomized controlled trials
    G Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Eur J Neurol 20:1204-11. 2013
    ..To identify adverse events (AEs) significantly associated with perampanel treatment in double-blind clinical studies (RCTs). Serious AEs, study withdrawals due to AEs and dose-effect responses of individual AEs were also investigated...
  4. doi Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Firenze, Italy
    Seizure 22:528-36. 2013
    ..Indirect comparisons of patients withdrawing because of AEs, and the incidence of some vestibulocerebellar AEs between these three antiepileptic dugs (AEDs)...
  5. doi AMPA receptor inhibitors for the treatment of epilepsy: the role of perampanel
    Gaetano Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Expert Rev Neurother 13:647-55. 2013
    ..Weight increase is the only non-neurological adverse effects associated with perampanel...
  6. doi The adverse event profile of lacosamide: a systematic review and meta-analysis of randomized controlled trials
    Gaetano Zaccara
    Unit of Neurology, Department of Medicine, Florence Health Authority, Firenze, Italy
    Epilepsia 54:66-74. 2013
    ....
  7. doi Central nervous system adverse effects of new antiepileptic drugs. A meta-analysis of placebo-controlled studies
    G Zaccara
    Unit of Neurology, Piero Palagi Hospital, Viale Michelangelo 41, Florence, Firenze, Italy
    Seizure 17:405-21. 2008
    ....
  8. doi Neurological comorbidity and epilepsy: implications for treatment
    G Zaccara
    Unit of Neurology, Palagi Hospital, Viale Michelangelo 41, Florence, Italy
    Acta Neurol Scand 120:1-15. 2009
    ....
  9. doi The adverse event profile of pregabalin: a systematic review and meta-analysis of randomized controlled trials
    Gaetano Zaccara
    U O Neurologia, Azienda Sanitaria di Firenze, Firenze, Italy
    Epilepsia 52:826-36. 2011
    ..We also assessed the association between serious AEs and pregabalin, and investigated whether pregabalin AEs display a dose-response relationship...
  10. doi Drug safety evaluation of zonisamide for the treatment of epilepsy
    Gaetano Zaccara
    Giovanni Di Dio Hospital, Unit of Neurology, Firenze, Italy
    Expert Opin Drug Saf 10:623-31. 2011
    ..Zonisamide is a broad spectrum antiepileptic drug with multiple mechanisms of action which has been recently approved in the US and Europe as an adjunctive therapy for refractory partial seizures in adults...
  11. ncbi Motor control in mirror movements: studies with transcranial magnetic stimulation
    M Cincotta
    U O di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova 1, 50122 Florence, Italy
    Suppl Clin Neurophysiol 56:175-80. 2003
  12. ncbi Modulatory effects of high-frequency repetitive transcranial magnetic stimulation on the ipsilateral silent period
    M Cincotta
    Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1, 50122, Florence, Italy
    Exp Brain Res 171:490-6. 2006
    ..The ISP facilitation induced by high-frequency rTMS is a novel, promising tool to investigate pathophysiological abnormal interhemispheric inhibitory transfer in various neurological diseases...
  13. ncbi Role of the right dorsal premotor cortex in "physiological" mirror EMG activity
    F Giovannelli
    Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Florence, Italy
    Exp Brain Res 175:633-40. 2006
    ..These findings strongly support the hypothesis that the right dPMC is part of the non-mirror transformation cortical network...
  14. ncbi Physical interactions between induced electrical fields can have substantial effects on neuronal excitation during simultaneous TMS of two brain areas
    M Cincotta
    Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1, 50122 Firenze, Italy
    Clin Neurophysiol 116:1733-42. 2005
    ..To analyse the interactions between simultaneous or nearly simultaneous focal transcranial magnetic stimulation (TMS) of the motor cortex hand area (M1hand) of both hemispheres...
  15. ncbi Suprathreshold 0.3 Hz repetitive TMS prolongs the cortical silent period: potential implications for therapeutic trials in epilepsy
    M Cincotta
    Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1 50122, Florence, Italy
    Clin Neurophysiol 114:1827-33. 2003
    ..To investigate the after-effects of 0.3 Hz repetitive transcranial magnetic stimulation (rTMS) on excitatory and inhibitory mechanisms at the primary motor cortex level, as tested by single-pulse TMS variables...
  16. doi Mild cognitive impairment: loss of linguistic task-induced changes in motor cortex excitability
    L Bracco
    Department of Neurological and Psychiatric Sciences, University of Florence, Florence Health Authority, Florence, Italy
    Neurology 72:928-34. 2009
    ..We used TMS to investigate functional connectivity between language-related cortical areas and M1(hand) in aMCI...
  17. ncbi Congenital hemiparesis: different functional reorganization of somatosensory and motor pathways
    A Ragazzoni
    Unit of Neurology, Santa Maria Nuova Hospital, Piazza S Maria Nuova, 1, Florence, Italy
    Clin Neurophysiol 113:1273-8. 2002
    ..To investigate the reorganization of somatosensory and motor cortex in congenital brain injury...
  18. ncbi Adverse motor effects induced by antiepileptic drugs
    G Zaccara
    Unit of Neurology, S Maria Nuova Hospital, Fierenze, Italy
    Epileptic Disord 6:153-68. 2004
    ..Finally, we summarize the role of sophisticated technical studies which provide a valuable insight into the specific or subtle effects of AEDs on the central nervous system...
  19. ncbi Remote effects of cortical dysgenesis on the primary motor cortex: evidence from the silent period following transcranial magnetic stimulation
    M Cincotta
    Unita Operativa di Neurologia, Azienda Sanitaria N 10 Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1, 50122, Firenze, Italy
    Clin Neurophysiol 111:1340-5. 2000
    ..Cerebral areas projecting to the primary motor cortex (M1) modulate the cortical silent period (CSP) following transcranial magnetic stimulation (TMS). Therefore, we used the CSP to investigate remote effects of CD on the M1...
  20. ncbi Bilateral motor cortex output with intended unimanual contraction in congenital mirror movements
    M Cincotta
    Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy
    Neurology 58:1290-3. 2002
    ..Thus, it is likely that the shortened CSP after unilateral TMS is caused by output from the nonstimulated M1, suggesting that both M1 produce output with intended unimanual movements in patients with MM...
  21. ncbi Cortical silent period in two patients with meningioma and preoperative seizures: a pre- and postsurgical follow-up study
    Massimo Cincotta
    Unita Operativa di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova 1, 50122, Florence, Italy
    Clin Neurophysiol 113:597-603. 2002
    ..This study aimed to investigate the relationship between the expected intraindividual variations in risk factors for seizures and CSP duration...
  22. ncbi Event-related potentials in patients with total locked-in state due to fulminant Guillain-Barré syndrome
    A Ragazzoni
    Neurology Unit, Ospedale S Maria Nuova, Florence, Italy
    Int J Psychophysiol 37:99-109. 2000
    ..ERPs allow monitoring the level of alertness and attention and appear more specific than EEG in identifying a state of awareness in patients in which communication is severely impaired as a consequence of neurological disorders...
  23. ncbi Cost effectiveness of riluzole in amyotrophic lateral sclerosis. Italian Cooperative Group for the Study of Meta-Analysis and the Osservatorio SIFO sui Farmaci
    A Messori
    Drug Information Centre, Pharmaceutical Service, Azienda Ospedaliera Careggi, Florence, Italy
    Pharmacoeconomics 16:153-63. 1999
    ..We conducted a pharmacoeconomic analysis for estimating the cost per life-year gained using this drug...
  24. ncbi Current approaches to the use of generic antiepileptic drugs
    G Kramer
    Swiss Epilepsy Center, Bleulerstrasse 60, Ch 8008 Zurich, Switzerland
    Epilepsy Behav 11:46-52. 2007
    ..Both physicians and patients have a right to be informed and approve before pharmacists make a generic substitution or switch between generics...