Arianna Vignini

Summary

Country: Italy

Publications

  1. ncbi Reactive oxygen species plasmatic levels in ischemic stroke
    Laura Nanetti
    Institute of Biochemistry, Universita Politecnica delle Marche, Ancona, Italy
    Mol Cell Biochem 303:19-25. 2007
  2. ncbi Environmental and genetical aspects of the link between pregnancy, birth size, and type 2 diabetes
    Arianna Vignini
    Department of Clinical Sciences, Section of Biochemistry and Biology, Universita Politecnica Marche, Ancona, Italy
    Curr Diabetes Rev 8:155-61. 2012
  3. ncbi Modifications of platelet from Alzheimer disease patients: a possible relation between membrane properties and NO metabolites
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Universita Politecnica delle Marche, Ancona, Italy
    Neurobiol Aging 28:987-94. 2007
  4. ncbi Alterations of platelet biochemical and functional properties in newly diagnosed type 1 diabetes: a role in cardiovascular risk?
    Arianna Vignini
    Department of Biochemistry, Biology and Genetics, School of Medicine, Polytechnic University of Marche, Via Ranieri 65, Ancona, Italy
    Diabetes Metab Res Rev 27:277-85. 2011
  5. ncbi A study on the action of vitamin E supplementation on plasminogen activator inhibitor type 1 and platelet nitric oxide production in type 2 diabetic patients
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Via P Ranieri 65, 60131 Ancona, Italy
    Nutr Metab Cardiovasc Dis 18:15-22. 2008
  6. ncbi Platelet nitric oxide production and IR: relation with obesity and hypertriglyceridemia
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnical University of Marche, Via P Ranieri 65, 60131 Ancona, Italy
    Nutr Metab Cardiovasc Dis 18:553-8. 2008
  7. ncbi Lipoproteins obtained from anorexia nervosa patients induce higher oxidative stress in U373MG astrocytes through nitric oxide production
    Arianna Vignini
    Institute of Biochemistry School of Medicine, Polytechnic University of Marche, Via P Ranieri 65, Ancona, 60131, Italy
    Neuromolecular Med 10:17-23. 2008
  8. ncbi Anorexia nervosa: a role for L-arginine supplementation in cardiovascular risk factors?
    Arianna Vignini
    Department of Biochemistry, Biology and Genetics, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Int J Eat Disord 43:464-71. 2010
  9. ncbi Free thiols in human spermatozoa: are Na+/K+-ATPase, Ca2+-ATPase activities involved in sperm motility through peroxynitrite formation?
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Ancono, Italy
    Reprod Biomed Online 18:132-40. 2009
  10. ncbi Oxidative stress in ischaemic stroke
    Laura Nanetti
    Department of Biology, Universita Politecnica delle Marche, Ancona, Italy
    Eur J Clin Invest 41:1318-22. 2011

Collaborators

Detail Information

Publications36

  1. ncbi Reactive oxygen species plasmatic levels in ischemic stroke
    Laura Nanetti
    Institute of Biochemistry, Universita Politecnica delle Marche, Ancona, Italy
    Mol Cell Biochem 303:19-25. 2007
    ..Peroxynitrite might be the main marker of brain damage and neurological impairment in acute ischemic stroke...
  2. ncbi Environmental and genetical aspects of the link between pregnancy, birth size, and type 2 diabetes
    Arianna Vignini
    Department of Clinical Sciences, Section of Biochemistry and Biology, Universita Politecnica Marche, Ancona, Italy
    Curr Diabetes Rev 8:155-61. 2012
    ..In this paper the factors that participate in the programming of the fetus and infants that lead to endocrine dysfunction in postnatal life are reviewed...
  3. ncbi Modifications of platelet from Alzheimer disease patients: a possible relation between membrane properties and NO metabolites
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Universita Politecnica delle Marche, Ancona, Italy
    Neurobiol Aging 28:987-94. 2007
    ..These modifications may contribute further to the neurodegenerative process in AD because the abnormal function of Alzheimer platelets play a very important role in the pathogenesis of the disease...
  4. ncbi Alterations of platelet biochemical and functional properties in newly diagnosed type 1 diabetes: a role in cardiovascular risk?
    Arianna Vignini
    Department of Biochemistry, Biology and Genetics, School of Medicine, Polytechnic University of Marche, Via Ranieri 65, Ancona, Italy
    Diabetes Metab Res Rev 27:277-85. 2011
    ..The aim of this study was to investigate whether T1D at onset is able to induce alterations of platelet physicochemical and functional properties and whether these changes are affected by hyperglycaemia...
  5. ncbi A study on the action of vitamin E supplementation on plasminogen activator inhibitor type 1 and platelet nitric oxide production in type 2 diabetic patients
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Via P Ranieri 65, 60131 Ancona, Italy
    Nutr Metab Cardiovasc Dis 18:15-22. 2008
    ....
  6. ncbi Platelet nitric oxide production and IR: relation with obesity and hypertriglyceridemia
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnical University of Marche, Via P Ranieri 65, 60131 Ancona, Italy
    Nutr Metab Cardiovasc Dis 18:553-8. 2008
    ..The aim of the present work was to examine eNOS polymorphism, to find a correlation with platelet NO production and degree of insulin resistance (IR) in non-diabetic subjects and in patients affected by type 2 diabetes...
  7. ncbi Lipoproteins obtained from anorexia nervosa patients induce higher oxidative stress in U373MG astrocytes through nitric oxide production
    Arianna Vignini
    Institute of Biochemistry School of Medicine, Polytechnic University of Marche, Via P Ranieri 65, Ancona, 60131, Italy
    Neuromolecular Med 10:17-23. 2008
    ..Thus, a relevant pathophysiological association between NO and depression is certainly a possibility, as well as a central role played by NO in the pathogenesis...
  8. ncbi Anorexia nervosa: a role for L-arginine supplementation in cardiovascular risk factors?
    Arianna Vignini
    Department of Biochemistry, Biology and Genetics, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Int J Eat Disord 43:464-71. 2010
    ..The aim of the present study was to evaluate the effects of a short-term oral L-arginine treatment on platelet NO production, intracellular calcium concentration, iNOS and eNOS expression, in AN patients...
  9. ncbi Free thiols in human spermatozoa: are Na+/K+-ATPase, Ca2+-ATPase activities involved in sperm motility through peroxynitrite formation?
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Ancono, Italy
    Reprod Biomed Online 18:132-40. 2009
    ..Decrease in motility and loss of sperm function in idiopathic asthenozoospermia can be attributed to these sulphydryl groups, important entities of the sperm membrane...
  10. ncbi Oxidative stress in ischaemic stroke
    Laura Nanetti
    Department of Biology, Universita Politecnica delle Marche, Ancona, Italy
    Eur J Clin Invest 41:1318-22. 2011
    ..Production of reactive oxygen species after ischaemic stroke may enhance tissue damage through multiple molecular pathways...
  11. ncbi The production of peroxynitrite by human spermatozoa may affect sperm motility through the formation of protein nitrotyrosine
    Arianna Vignini
    Institute of Biochemistry, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Fertil Steril 85:947-53. 2006
    ..Motility parameters are negatively affected, suggesting that ONOO- may be involved in defective sperm function...
  12. ncbi Interactions between lipoproteins and platelet membranes in obesity
    Francesca Raffaelli
    Department of Biochemistry, Biology and Genetics, School of Medicine, Marche Polytechnic University, Ancona, Italy
    Obesity (Silver Spring) 17:1375-80. 2009
    ..The present data point out that obesity might represent a major potentially modifiable risk factor for the onset of numerous complications, in particular cardiovascular ones...
  13. ncbi Nitric oxide platelet production in spontaneous miscarriage in the first trimester
    Francesca Raffaelli
    Department of Biochemistry, Biology and Genetics, Marche Polytechnic University, Ancona, Italy
    Fertil Steril 93:1976-82. 2010
    ..To investigate the role played by platelet nitric oxide (NO) metabolism in patients with spontaneous miscarriage (SM) and recurrent spontaneous miscarriage (RSM) compared with healthy pregnant women...
  14. ncbi Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study
    Eleonora Salvolini
    Department of Clinical and Molecular Sciences Histology, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Fertil Steril 97:554-60. 2012
    ..Also to evaluate the immunohistochemical expression of citrulline, a marker of NOS activity, and nitrotyrosine, which indicates the formation of peroxynitrite, which may affect sperm functionality through its cytotoxic action...
  15. ncbi Reduced nitric oxide levels in acromegaly: cardiovascular implications
    Vanessa Ronconi
    Division of Endocrinology, Department of Internal Medicine, , Ospedali Riuniti Umberto I-GM Lancisi-G Salesi, Ancona, Italy
    Blood Press 14:227-32. 2005
    ..Moreover the inverse correlation of NO levels with GH, IGF-1 and disease duration suggests that reduced levels of platelet NO linked to GH excess may contribute to the vascular alterations affecting patients with acromegaly...
  16. ncbi Platelet membrane fluidity and Na+/K+ ATPase activity in acute stroke
    Laura Nanetti
    Institute of Biochemistry, Marche Polytechnic University, Italy
    Brain Res 1205:21-6. 2008
    ..These modifications and their interaction with some vascular risk factors might be involved in the pathogenesis of ischemic damage development...
  17. ncbi Nitric oxide and peroxynitrite platelet levels in gestational hypertension and preeclampsia
    Laura Mazzanti
    Department of Biochemistry, Biology and Genetics, Marche Polytechnic University, via Tronto 10 60128 Ancona, Italy
    Platelets 23:26-35. 2012
    ....
  18. ncbi Role of nitric oxide concentrations on human sperm motility
    Giancarlo Balercia
    Endocrinology Division, Department of Internal Medicine, University of Ancona, Ancona, Italy
    J Androl 25:245-9. 2004
    ..The positive role played by NO in spermatozoa capacitation leads us to speculate that such paradoxical involvement in both pathologic and physiologic processes depends on the alternative redox state and relative level of NO...
  19. ncbi Glutamate in vitro effects on human term placental mitochondria
    Eleonora Salvolini
    Department of Molecular Pathology and Innovative Therapies Histology, Polytechnic University of Marche, Ancona, Italy
    J Matern Fetal Neonatal Med 25:952-6. 2012
    ....
  20. ncbi Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial
    Giancarlo Balercia
    Department of Internal Medicine and Applied Biotechnologies, Andrology Unit, Endocrinology, Umberto I Hospital, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Fertil Steril 91:1785-92. 2009
    ..To evaluate the effectiveness of coenzyme Q(10) treatment in improving semen quality in men with idiopathic infertility...
  21. ncbi Effect of homocysteinylation of low density lipoproteins on lipid peroxidation of human endothelial cells
    Gianna Ferretti
    Istituto di Biochimica, , , Ancona, Italy
    J Cell Biochem 92:351-60. 2004
    ..These results suggest that Hcy-LDL exert a cytotoxic effect that is likely related to an increase in lipid peroxidation and oxidative damage of EC...
  22. ncbi Age-related changes on platelet membrane: a study on elderly and centenarian monozygotic twins
    Laura Nanetti
    Institute of Biochemistry, Polytechnic Marche University, School of Medicine, Via Ranieri 65, 60131 Ancona, Italy
    Exp Gerontol 40:519-25. 2005
    ..Thus genetic factors might play an important role in the mechanisms at the basis of successful aging...
  23. ncbi Single nucleotide polymorphism (SNP) of the endothelial nitric oxide synthase (eNOS) gene (Glu298Asp variant) in infertile men with asthenozoospermia
    Eddi Buldreghini
    Andrology Unit, Endocrinology, Department of Internal Medicine and Applied Biotechnologies, Umberto I Hospital, Torrette, Via Conca, 60100 Ancona, Italy
    J Androl 31:482-8. 2010
    ..03) and heterozygous eNOS (GT) genotypes (P = .04). Our findings suggest that the T allele encoding for aspartic acid of the eNOS (Glu298Asp) gene may contribute to poor sperm motility...
  24. ncbi Impact of gender on platelet membrane functions of Alzheimer's disease patients
    Arianna Vignini
    Department of Clinical Science Biochemistry, School of Medicine, Polytechnic University of Marche, Ancona, Italy
    Exp Gerontol 48:319-25. 2013
    ..Studies on gender differences could lead to a higher probability of improved health outcomes via better-targeted therapies...
  25. ncbi Evidence for reduction of pro-atherosclerotic properties in platelets from healthy centenarians
    Rosa Anna Rabini
    Department of Diabetology Research, Italian National Research Center on Aging, Ancona, Italy
    Exp Gerontol 38:367-71. 2003
    ....
  26. ncbi The effects of disodium pamidronate on human polymorphonuclear leukocytes and platelets: an in vitro study
    Eleonora Salvolini
    Department of Molecular Pathology and Innovative Therapies Histology, Polytechnic University of Marche, Via Tronto 10 A, 60020, Ancona, Italy
    Cell Mol Biol Lett 14:457-65. 2009
    ..In addition, PMN- and platelet-derived NO could act as a negative feed-back signal to restrict the inflammatory processes...
  27. ncbi VEGF and nitric oxide synthase immunoexpression in Down's syndrome amniotic fluid stem cells
    Eleonora Salvolini
    Department of Molecular Pathology and Innovative Therapies Histology Section, Polytechnic University of Marche, Ancona, Italy
    Eur J Clin Invest 41:23-9. 2011
    ..In addition, we measured the VEGF and NO content in cell culture supernatants to analyse their production by AF-MSCs...
  28. ncbi Activation of human aortic endothelial cells by LDL from Type 1 diabetic patients: an in vitro study
    Rosa A Rabini
    Department of Diabetology, Italian National Research Center on Aging, Ancona, Italy
    Atherosclerosis 165:69-77. 2002
    ..The results suggest that a short-term interaction with LDL from Type 1 diabetic patients causes alterations of the plasma membrane surface and of cellular functions in endothelial cells in a possibly atherogenic way...
  29. ncbi Protective effect of human HDL against Cu(2+)-induced oxidation of astrocytes
    Gianna Ferretti
    Institute of Biochemistry, Faculty of Medicine, University of Ancona, Ancona, Italy
    J Trace Elem Med Biol 17:25-30. 2003
    ....
  30. ncbi Prognostic significance of personality profiles in patients with chronic migraine
    Roberta Luconi
    Department of Neuroscience, Polytechnic University of Marche, Ancona, Italy
    Headache 47:1118-24. 2007
    ..The aim of this study was to assess whether the psychological profile may have prognostic significance in chronic migraine patients...
  31. ncbi Placental expression of endothelial and inducible nitric oxide synthase and nitric oxide levels in patients with HELLP syndrome
    Laura Mazzanti
    Department of Biochemistry, Biology and Genetics, Universita Politecnica Marche, Ancona, Italy
    Am J Obstet Gynecol 205:236.e1-7. 2011
    ..To determine placental gene expression of endothelial and inducible nitric oxide synthases and measure nitric oxide levels in patients with hemolysis, elevated liver enzyme levels, and low platelet count syndrome...
  32. ncbi Cytotoxic effects induced by hexachlorobenzene in Squilla mantis (L.) (Crustacea, Stomatopoda)
    Antonio Dell'Anno
    Department of Marine Science, Faculty of Science, Polytechnic University of Marche, Via Brecce Bianche, 60131, Ancona, Italy
    Environ Toxicol 23:9-14. 2008
    ..Overall these findings suggest that even small concentrations of HCB may determine important changes on cell metabolism with potential cascade effects on recruitment of this commercial species...
  33. ncbi Nitric oxide production during the osteogenic differentiation of human periodontal ligament mesenchymal stem cells
    Monia Orciani
    Dipartimento di Patologia Molecolare e Terapie Innovative Istologia, Universita Politecnica delle Marche, Via Tronto 10 A, 60020 Ancona, Italy
    Acta Histochem 111:15-24. 2009
    ....
  34. ncbi Follicular fluid nitric oxide (NO) concentrations in stimulated cycles: the relationship to embryo grading
    Arianna Vignini
    Institute of Biochemistry, Polytechnic University of Marche at Salesi Hospital, via Corridoni 11, Ancona, Italy
    Arch Gynecol Obstet 277:229-32. 2008
    ..We investigated the concentration of nitric oxide (NO) in follicular fluid, collected during oocyte retrieval after in-vitro fertilization and embryo transfer (IVF-ET) and its relationship to oocyte and embryo grading...
  35. ncbi Copper-induced oxidative damage on astrocytes: protective effect exerted by human high density lipoproteins
    Gianna Ferretti
    Istituto di Biochimica, , , Via Ranieri, I-60131 Ancona, Italy
    Biochim Biophys Acta 1635:48-54. 2003
    ....
  36. ncbi Evidence for S-nitrosothiol-dependent changes in fibrinogen that do not involve transnitrosation or thiolation
    Shirin Akhter
    Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON, Canada N9B
    Proc Natl Acad Sci U S A 99:9172-7. 2002
    ..Three such putative RSNO-binding domains have been identified in the unordered, aromatic residue-rich C-termini of the alpha-chains of fibrinogen...