Pietro Vajro

Summary

Affiliation: Via Ponte Don Melillo
Country: Italy

Publications

  1. pmc Zinc monotherapy is effective in Wilson's disease patients with mild liver disease diagnosed in childhood: a retrospective study
    Giusy Ranucci
    Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy
    Orphanet J Rare Dis 9:41. 2014
  2. pmc Health-related quality of life in pediatric liver transplanted patients compared with a chronic liver disease group
    Antonella Gritti
    Faculty of Education Science, Suor Orsola Benincasa University, Naples, Italy
    Ital J Pediatr 39:55. 2013
  3. pmc Nutritional problems in children with neuromotor disabilities: an Italian case series
    Maria Sangermano
    Chair of Pediatrics, Department of Medicine and Surgery, Pediatrics Section, University of Salerno, via Allende, 84081 Baronissi Salerno, Italy
    Ital J Pediatr 40:61. 2014
  4. doi request reprint Management of adults with paediatric-onset chronic liver disease: strategic issues for transition care
    Pietro Vajro
    Chair of Paediatrics, Department of Medicine and Surgery, University of Salerno, Baronissi Salerno, Italy Electronic address
    Dig Liver Dis 46:295-301. 2014
  5. doi request reprint Treatment of children with chronic viral hepatitis: what is available and what is in store
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, Italy
    World J Pediatr 9:212-20. 2013
  6. pmc Pediatric non alcoholic fatty liver disease: more on novel treatment targets
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno, Via S, Allende, 84081 Baronissi Salerno, Italy
    BMC Pediatr 13:109. 2013
  7. doi request reprint Pediatric celiac disease, cryptogenic hypertransaminasemia, and autoimmune hepatitis
    Pietro Vajro
    Department of Pediatrics, School of Medicine at the University of Salerno, Salerno, Italy
    J Pediatr Gastroenterol Nutr 56:663-70. 2013
  8. pmc Persistent hypertransaminasemia in asymptomatic children: a stepwise approach
    Pietro Vajro
    Department of Medicine and Surgery, Pediatrics, University of Salerno, 84081 Baronissi, Italy
    World J Gastroenterol 19:2740-51. 2013
  9. pmc Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno Medical School, Salerno, Italy
    J Pediatr Gastroenterol Nutr 56:461-8. 2013
  10. pmc Therapeutic options in pediatric non alcoholic fatty liver disease: current status and future directions
    Pietro Vajro
    Medical School of the University of Salerno, Salerno, Italy
    Ital J Pediatr 38:55. 2012

Collaborators

Detail Information

Publications39

  1. pmc Zinc monotherapy is effective in Wilson's disease patients with mild liver disease diagnosed in childhood: a retrospective study
    Giusy Ranucci
    Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy
    Orphanet J Rare Dis 9:41. 2014
    ..The treatment of WD patients with mild liver disease is not clearly defined. To address this issue, we evaluated long-term outcomes of three treatment regimens (D-penicillamine, zinc or both) in patients diagnosed in childhood...
  2. pmc Health-related quality of life in pediatric liver transplanted patients compared with a chronic liver disease group
    Antonella Gritti
    Faculty of Education Science, Suor Orsola Benincasa University, Naples, Italy
    Ital J Pediatr 39:55. 2013
    ..Purpose of our study is to compare HRQoL of PLT patients (N = 33, mean age 12.8 y) vs. sex and age matched patients with compensated and clinically stable chronic liver disease (CLD) (N = 25, mean age 11.9 y)...
  3. pmc Nutritional problems in children with neuromotor disabilities: an Italian case series
    Maria Sangermano
    Chair of Pediatrics, Department of Medicine and Surgery, Pediatrics Section, University of Salerno, via Allende, 84081 Baronissi Salerno, Italy
    Ital J Pediatr 40:61. 2014
    ....
  4. doi request reprint Management of adults with paediatric-onset chronic liver disease: strategic issues for transition care
    Pietro Vajro
    Chair of Paediatrics, Department of Medicine and Surgery, University of Salerno, Baronissi Salerno, Italy Electronic address
    Dig Liver Dis 46:295-301. 2014
    ....
  5. doi request reprint Treatment of children with chronic viral hepatitis: what is available and what is in store
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno, Baronissi, Salerno, Italy
    World J Pediatr 9:212-20. 2013
    ..Our review deals with pros and cons points when a physician decides to design a drug therapy for a child with chronic viral hepatitis, and different possible therapeutic opportunities...
  6. pmc Pediatric non alcoholic fatty liver disease: more on novel treatment targets
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno, Via S, Allende, 84081 Baronissi Salerno, Italy
    BMC Pediatr 13:109. 2013
    ..g., insulin resistance, oxidative stress, gut-liver axis, apoptosis) along with lifestyle interventions however might be necessary both in adult and pediatric NAFLD therapy. ..
  7. doi request reprint Pediatric celiac disease, cryptogenic hypertransaminasemia, and autoimmune hepatitis
    Pietro Vajro
    Department of Pediatrics, School of Medicine at the University of Salerno, Salerno, Italy
    J Pediatr Gastroenterol Nutr 56:663-70. 2013
    ..This study aims to conduct a systematic review and meta-analysis to evaluate the prevalence of CD in children with cryptogenic persistent hypertransaminasemia (HTS) or autoimmune hepatitis (AIH), and vice versa...
  8. pmc Persistent hypertransaminasemia in asymptomatic children: a stepwise approach
    Pietro Vajro
    Department of Medicine and Surgery, Pediatrics, University of Salerno, 84081 Baronissi, Italy
    World J Gastroenterol 19:2740-51. 2013
    ..Given the high benefit/cost ratio of preventing hepatic deterioration, no effort should be spared in diagnosing and properly treating each case of persistent hypertransaminasemia in pediatric patients...
  9. pmc Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease
    Pietro Vajro
    Department of Medicine and Surgery, University of Salerno Medical School, Salerno, Italy
    J Pediatr Gastroenterol Nutr 56:461-8. 2013
    ..Interactions between gut microbiota and other factors (eg, inflammasome deficiency) also are reviewed as emerging but far from being completely elucidated mechanisms influencing the onset of obesity and nonalcoholic fatty liver disease...
  10. pmc Therapeutic options in pediatric non alcoholic fatty liver disease: current status and future directions
    Pietro Vajro
    Medical School of the University of Salerno, Salerno, Italy
    Ital J Pediatr 38:55. 2012
    ..Toll-like receptors modifiers, Pentoxifylline, and Farnesoid X receptors agonists have been still poorly investigated, and will need further studies before becoming possible promising innovative therapeutic strategies...
  11. pmc Characterization and burden of Campania children health migration across Italian regions during years 2006-2010: chance and/or necessity?
    Pietro Vajro
    Medical School of the University of Salerno, Italy
    Ital J Pediatr 38:58. 2012
    ..To evaluate medical, economical and sociological variables underlying avoidable pediatric migration from Campania region...
  12. doi request reprint Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology Committee
    Pietro Vajro
    Department of Pediatrics, Medical School, University of Salerno, Salerno, Italy
    J Pediatr Gastroenterol Nutr 54:700-13. 2012
    ....
  13. doi request reprint Alagille syndrome: an overview
    Pietro Vajro
    Medical School of Salerno, Salerno, Italy
    Clin Res Hepatol Gastroenterol 36:275-7. 2012
    ..The other features are a peculiar facies, cardiac abnormalities, butterfly vertebrae, and ocular embryotoxon. The prognosis depends on the severity of the liver and heart diseases. Hepatocarcinoma has been reported...
  14. doi request reprint Autoimmune hepatitis: current knowledge
    Pietro Vajro
    Medical School of Salerno, Salerno, Italy
    Clin Res Hepatol Gastroenterol 36:284-6. 2012
    ..The treatment with steroids and azathioprine is efficient in most cases. Cyclosporine A is also successfully used. Relapses under treatment are frequent. A long-term treatment may be necessary. Liver transplantation is rarely indicated...
  15. doi request reprint Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease
    Pietro Vajro
    Departments of Pediatrics, University of Naples Federico II, Naples, Italy
    J Pediatr Gastroenterol Nutr 52:740-3. 2011
    ..We evaluated the effects of short-term probiotic treatment in children with obesity-related liver disease who were noncompliant with lifestyle interventions...
  16. doi request reprint Clinical features and genotype-phenotype correlations in children with progressive familial intrahepatic cholestasis type 3 related to ABCB4 mutations
    Carla Colombo
    Department of Pediatrics, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
    J Pediatr Gastroenterol Nutr 52:73-83. 2011
    ....
  17. doi request reprint Re-evaluation of the diagnostic criteria for Wilson disease in children with mild liver disease
    Emanuele Nicastro
    Department of Pediatrics, University Federico II, Naples, Italy
    Hepatology 52:1948-56. 2010
    ..The WD scoring system was proved to have positive and negative predictive values of 93% and 91.6%, respectively...
  18. doi request reprint Indications and Limitations of Bariatric Intervention in Severely Obese Children and Adolescents With and Without Nonalcoholic Steatohepatitis: ESPGHAN Hepatology Committee Position Statement
    Valerio Nobili
    Unit of Hepato Metabolic Diseases, Bambino Gesu Children s Hospital, IRCCS, Rome Department of Medicine and Surgery, Pediatric Section, University of Salerno, Baronissi Salerno, Italy First Department of Pediatrics, Semmelweis University, Semmelweis, Hungary Department of Pediatrics, Karolinska University Hospital, CLINTEC, Karolinska Institutet, Stockholm, Sweden Paediatric Gastrointestinal, Liver and Nutrition Centre Variety Children s Hospital King s College Hospital NHS Foundation Trust Denmark Hill Camberwell, London, UK Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University Graz, Graz, Austria Pediatric Gastroenterology Unit, Children s Hospital, Place Amelie Raba, Bordeaux, France Liver Unit, Birmingham Children s Hospital, Birmingham, UK Swiss Center for Liver Disease in Children, Pediatric Gastroenterology Unit, Department of Pediatrics, University Hospitals, Geneva, Switzerland Department of Gastroenterology, Hepatology and Eating Disorders, Children s Memorial Health Institute, Warsaw, Poland Paediatric Viral Hepatitis
    J Pediatr Gastroenterol Nutr 60:550-61. 2015
    ....
  19. ncbi request reprint Vitamin E treatment in pediatric obesity-related liver disease: a randomized study
    Pietro Vajro
    Department of Pediatrics, University of Naples Federico II, Italy
    J Pediatr Gastroenterol Nutr 38:48-55. 2004
    ..The authors compared the effect of vitamin E and weight loss on transaminase values and on ultrasonographic bright liver in a controlled group of children with obesity-related liver dysfunction...
  20. ncbi request reprint Metabolic, hormonal, oxidative, and inflammatory factors in pediatric obesity-related liver disease
    Claudia Mandato
    Department of Pediatrics, European Laboratory for the Investigation of Food Induced Diseases, University of Naples, Naples, Italy
    J Pediatr 147:62-6. 2005
    ..To examine the role of metabolic, hormonal, oxidative, and inflammatory factors in pediatric obesity-related liver disease...
  21. doi request reprint Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model
    Vera Gallo
    Department of Pediatrics, Federico II University, S Pansini 5, 8013 Naples, Italy
    Expert Rev Clin Immunol 9:43-51. 2013
    ..This review focuses on recent advances in the molecular mechanisms of central tolerance, their alterations and clinical implication...
  22. pmc Fatty liver disease and hypertransaminasemia hiding the association of clinically silent Duchenne muscular dystrophy and hereditary fructose intolerance
    Giulia Paolella
    School of Medicine, University of Salerno, Salerno, Italy
    Ital J Pediatr 38:64. 2012
    ..This case illustrates the problems of a correct diagnosis in sub-clinical patients presenting with "cryptogenic" hypertransaminasemia...
  23. doi request reprint Genotype-phenotype correlation in Italian children with Wilson's disease
    Emanuele Nicastro
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    J Hepatol 50:555-61. 2009
    ..Wilson's disease phenotype is very variable for clinical and laboratory features. Our aim was to assess the role of the type of ATP7B disease causing mutations on Wilson's disease phenotype...
  24. ncbi request reprint Cryptogenic liver disease in four children: a novel congenital disorder of glycosylation
    Claudia Mandato
    Department of Pediatrics, University of Naples Federico II, Italy
    Pediatr Res 59:293-8. 2006
    ..Clinicians are encouraged to test such patients for abnormal Tf glycosylation by ESI-MS...
  25. doi request reprint Prevalence and long-term course of macro-aspartate aminotransferase in children
    Maria Caropreso
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    J Pediatr 154:744-8. 2009
    ..To investigate the prevalence, association with clinical conditions, and long-term course of macro-aspartate aminotransferase (macro-AST)...
  26. doi request reprint Liver biopsy in children: position paper of the ESPGHAN Hepatology Committee
    Antal Dezsofi
    First Department of Pediatrics, Semmelweis University, Budapest, Hungary Paediatric Gastroenterology and Hepatology, Hannover Medical School, Hannover, Germany Kings College London School of Medicine at Kings College Hospital, London, UK Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey Department of Pediatrics, CLINTEC, Karolinska University Hospital, Stockholm, Sweden Paediatric Centre for Hepatology, Gastroenterology and Nutrition, King s College Hospital, London, UK Pediatric Hepatology Service, Hospital Infantil Universitario La Paz, Madrid, Spain Necker Enfants Malades Hospital, Paris, France Pediatric Gastroenterology Unit, Department of Pediatrics, University Hospitals Geneva, Switzerland Hepatometabolic Unit, Bambino Gesu Children s Hospital, Rome, Italy Department of Gastroenterology, Hepatology and Nutritional Disturbances, Children s Memorial Health Institute, Warsaw, Poland Department of Medicine and Surgery, University of Salerno, Salerno, Italy Institute of Liver Studies King s College Hospital, London, UK
    J Pediatr Gastroenterol Nutr 60:408-20. 2015
    ..This position paper presents types of LB, indications, complications, contraindications, and an essential checklist for paediatric LB. ..
  27. doi request reprint Emerging pathomechanisms involved in obesity
    Roberta D'Aniello
    Department of Medicine and Surgery, Pediatrics Section, University of Salerno, Baronissi Pediatrics Section, Local Health Service ASL Salerno, Salerno, Italy
    J Pediatr Gastroenterol Nutr 60:113-9. 2015
    ..Our study focuses on these factors for further preventive/therapeutic approaches in paediatric obesity...
  28. pmc Gut-liver axis and probiotics: their role in non-alcoholic fatty liver disease
    Giulia Paolella
    Giulia Paolella, Luca Pierri, Marco Poeta, Martina Di Stasi, Pietro Vajro, Department of Medicine and Surgery, University of Salerno, 84081 Baronissi Salerno, Italy
    World J Gastroenterol 20:15518-31. 2014
    ..Globally, this approach appears to be a promising and innovative add-on therapeutic tool for NAFLD in the context of multi-target therapy. ..
  29. pmc Management of cholelithiasis in Italian children: a national multicenter study
    Claudia Della Corte
    Pediatric Liver Unit, Department of Pediatrics, University Federico II of Naples, Via S Pansini 5, Naples 80131, Italy
    World J Gastroenterol 14:1383-8. 2008
    ..To evaluate the management of Italian children with cholelithiasis observed at Pediatric and Surgical Departments linked to Italian Society of Pediatric Gastroenterology Hepatology and Nutrition...
  30. ncbi request reprint Per-rectal portal scintigraphy is complementary to ultrasonography and endoscopy in the assessment of portal hypertension in children with chronic cholestasis
    Pietro Vajro
    Department of Pediatrics, Medical School of the University of Naples Federico II, Naples, Italy
    J Nucl Med 45:1705-11. 2004
    ..We evaluated the clinical usefulness of 99mTc-pertechnetate per-rectal portal scintigraphy (PPS) in the assessment of portal circulation in children with chronic cholestasis...
  31. pmc A case of galactosemia misdiagnosed as cow's milk intolerance
    Roberto Della Casa
    Department of Pediatrics, Federico II University, Naples, Italy
    Ital J Pediatr 38:47. 2012
    ..This case exemplifies the problems in reaching a correct diagnosis in patients with metabolic diseases...
  32. pmc Precocious puberty in Turner Syndrome: report of a case and review of the literature
    Nicola Improda
    Department of Pediatrics, Federico II University of Naples, Naples, Italy
    Ital J Pediatr 38:54. 2012
    ..Approximately one third of girls with TS may undergo spontaneous puberty. Here we report on the case of a girl with a rare 45X0/47XXX mosaic TS exhibiting a precocious puberty...
  33. doi request reprint New strategies for the treatment of lysosomal storage diseases (review)
    Giancarlo Parenti
    Department of Pediatrics, Federico II University, Naples, Italy
    Int J Mol Med 31:11-20. 2013
    ..The recent progress made in the treatment of LSDs represents a good model that may be extended to other genetic disorders...
  34. pmc Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: insights into genotype-phenotype correlation
    Donatella Capalbo
    Department of Pediatrics, University of Naples Federico II, 80131 Naples, Italy
    Int J Endocrinol 2012:353250. 2012
    ..The aim of this paper is to give an overview on the clinical presentation and diagnostic criteria of APECED and to focus on current knowledge on genotype-phenotype correlation...
  35. ncbi request reprint Emotional and behavioral problems after pediatric liver transplantation: a quantitative assessment
    Antonella Gritti
    Department of Psychiatry, Child Neuropsychiatry, Audiophonology and Dermatology, Second University of Naples, Naples, Italy
    Pediatr Transplant 10:205-9. 2006
    ..Regarding Total Behavioral Problems and Externalizing Problems, this risk is higher than in children with chronic liver disease...
  36. doi request reprint Shwachman-Diamond syndrome with autoimmune-like liver disease and enteropathy mimicking celiac disease
    Claudio Veropalumbo
    Pediatrics Section, University of Naples Federico II, Naples, Italy Electronic address
    Clin Res Hepatol Gastroenterol 39:e1-4. 2015
    ..Our report may stimulate other studies to define the relationship between the SDS genetic defect and intestinal permeability as the pathogenic mechanism underlying SDS related liver and intestinal inflammation. ..
  37. ncbi request reprint Characterization of liver involvement in defects of cholesterol biosynthesis: long-term follow-up and review
    Massimiliano Rossi
    Department of Pediatrics, Federico II University, Naples, Italy
    Am J Med Genet A 132:144-51. 2005
    ..Periodic liver function evaluations are recommended in these patients...
  38. doi request reprint Celiac disease-associated autoimmune hepatitis in childhood: long-term response to treatment
    Silvia Nastasio
    Department of Clinical and Experimental Medicine, Division of Pediatric Gastroenterology, University of Pisa, Pisa, Italy
    J Pediatr Gastroenterol Nutr 56:671-4. 2013
    ..The aim of the present study was to analyze the features and the long-term response to immunosuppressive treatment in children with autoimmune hepatitis (AIH) associated with CD...