Luca Parente

Summary

Affiliation: Via Ponte Don Melillo
Country: Italy

Publications

  1. ncbi request reprint Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight
    Luca Parente
    Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Biochem Pharmacol 65:153-9. 2003
  2. ncbi request reprint Annexin 1: more than an anti-phospholipase protein
    Luca Parente
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Inflamm Res 53:125-32. 2004
  3. doi request reprint Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1
    Cosimo Walter D'Acunto
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano, Salerno, Italy
    Cancer Lett 295:85-91. 2010
  4. pmc Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Salerno, Italy
    PLoS ONE 7:e45639. 2012
  5. ncbi request reprint LGP1, A histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis
    Cosimo Walter D'Acunto
    Department of Pharmaceutical Science, University of Salerno, via Ponte Don Melillo 84084 Fisciano Salerno, Italy
    Anticancer Res 30:887-94. 2010
  6. doi request reprint Annexin A1: novel roles in skeletal muscle biology
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano, Salerno, Italy
    J Cell Physiol 227:3007-15. 2012
  7. doi request reprint Role of Annexin A1 in mouse myoblast cell differentiation
    Valentina Bizzarro
    Department of Pharmaceutical Sciences, University of Salerno, Salerno, Italy
    J Cell Physiol 224:757-65. 2010
  8. doi request reprint R-roscovitine sensitizes anaplastic thyroid carcinoma cells to TRAIL-induced apoptosis via regulation of IKK/NF-kappaB pathway
    Michela Festa
    Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Salerno, Italy
    Int J Cancer 124:2728-36. 2009
  9. ncbi request reprint Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation
    Silvana Morello
    Department of Pharmaceutical Science, Biomedical Section, University of Salerno, Salerno, Italy
    Cancer Biol Ther 7:278-84. 2008
  10. pmc Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptors
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Salerno, Italy
    PLoS ONE 7:e48246. 2012

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight
    Luca Parente
    Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Biochem Pharmacol 65:153-9. 2003
    ..We propose that the complexity of the situation in the field of COX-derived mediators should be borne in mind when anti-inflammatory therapy is required...
  2. ncbi request reprint Annexin 1: more than an anti-phospholipase protein
    Luca Parente
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Inflamm Res 53:125-32. 2004
    ..Thus, ANXA1 may contribute to the anti-inflammatory signalling that allows safe post-apoptotic clearance of dead cells...
  3. doi request reprint Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of Annexin A1
    Cosimo Walter D'Acunto
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano, Salerno, Italy
    Cancer Lett 295:85-91. 2010
    ..The results suggest that elevated activity of HDACs is responsible for the reduction of ANXA1, indicating that ANXA1 expression is a contributing factor to the proapoptotic effects in prostate cancer...
  4. pmc Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Salerno, Italy
    PLoS ONE 7:e45639. 2012
    ....
  5. ncbi request reprint LGP1, A histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis
    Cosimo Walter D'Acunto
    Department of Pharmaceutical Science, University of Salerno, via Ponte Don Melillo 84084 Fisciano Salerno, Italy
    Anticancer Res 30:887-94. 2010
    ..In the present study, we investigated the effects of the novel HDACi LGP1, a new simplified analogue of FR235222, in human leukaemia U937 cells resistant to TRAIL-induced apoptosis...
  6. doi request reprint Annexin A1: novel roles in skeletal muscle biology
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano, Salerno, Italy
    J Cell Physiol 227:3007-15. 2012
    ..This suggests that ANXA1 may contribute to the regeneration of skeletal muscle tissue and may have therapeutic implications with respect to the development of ANXA1 mimetics...
  7. doi request reprint Role of Annexin A1 in mouse myoblast cell differentiation
    Valentina Bizzarro
    Department of Pharmaceutical Sciences, University of Salerno, Salerno, Italy
    J Cell Physiol 224:757-65. 2010
    ..The data reported here suggest for the first time that ANXA1 plays a role in myogenic differentiation...
  8. doi request reprint R-roscovitine sensitizes anaplastic thyroid carcinoma cells to TRAIL-induced apoptosis via regulation of IKK/NF-kappaB pathway
    Michela Festa
    Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Salerno, Italy
    Int J Cancer 124:2728-36. 2009
    ..The combination of R-roscovitine and TRAIL may represent a novel approach to the treatment of anaplastic thyroid carcinomas resistant to conventional chemotherapy...
  9. ncbi request reprint Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation
    Silvana Morello
    Department of Pharmaceutical Science, Biomedical Section, University of Salerno, Salerno, Italy
    Cancer Biol Ther 7:278-84. 2008
    ....
  10. pmc Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptors
    Valentina Bizzarro
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Salerno, Italy
    PLoS ONE 7:e48246. 2012
    ..These properties indicate that ANXA1 may be involved in a novel repair mechanism for skeletal muscle and may have therapeutic implications with respect to the development of ANXA1 mimetics...
  11. doi request reprint Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues
    Carmen Petronzi
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
    Eur J Med Chem 46:488-96. 2011
    ..To evaluate the affinity of BLQ and its analogues for hsPLA2, surface plasmon resonance (SPR) experiments were performed...
  12. pmc Carrageenan-induced mouse paw oedema is biphasic, age-weight dependent and displays differential nitric oxide cyclooxygenase-2 expression
    Inmaculada Posadas
    Department of Experimental Pharmacology, Faculty of Pharmacy, University of Naples Federico II, via D Montesano 49, Naples 80131, Italy
    Br J Pharmacol 142:331-8. 2004
    ..The present results are the first report on the differential expressions of eNOS, iNOS, COX-1 and COX-2 in response to carrageenan injection in the two phases of the mouse paw oedema...
  13. doi request reprint Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1
    Antonello Petrella
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, Fisciano, Salerno, Italy
    Eur J Cancer 44:740-9. 2008
    ..These results suggest that ANXA1 expression may mediate cycle arrest induced by low doses FR235222, whereas apoptosis induced by high doses FR235222 is associated to ANXA1 processing...
  14. ncbi request reprint Dexamethasone inhibits TRAIL-induced apoptosis of thyroid cancer cells via Bcl-xL induction
    Antonello Petrella
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Eur J Cancer 42:3287-93. 2006
    ..These results demonstrate that dexamethasone protects thyroid cancer cells from apoptosis induced by TRAIL. DEX acts via GR activation and up-regulation of the expression of the anti-apoptotic protein Bcl-xL...
  15. ncbi request reprint Anti-inflammatory effects of annexin-1: stimulation of IL-10 release and inhibition of nitric oxide synthesis
    Viviana Ferlazzo
    Department of Bio Pathology and Bio Medical Methodologies, University of Palermo, Palermo, Italy
    Int Immunopharmacol 3:1363-9. 2003
    ..In addition, ANX-1-stimulated IL-10 release may also be responsible for the inhibition of IL-12 mRNA expression and, consequently, IL-12 synthesis...
  16. ncbi request reprint Proteinase-activated receptor-2 mediates arterial vasodilation in diabetes
    Fiorentina Roviezzo
    Dipartimento di Farmacologia Sperimentale, Universita di Napoli Federico II, Italy
    Arterioscler Thromb Vasc Biol 25:2349-54. 2005
    ..Here, using nonobese diabetic (NOD) mice at different disease stages, we have evaluated the role of PAR2 in the arterial vascular response during diabetes progression...
  17. pmc Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo
    Mariarosaria Bucci
    Dipartimento di Farmacologia Sperimentale, Via Domenico Montesano 49, Universita di Napoli Federico II, 80131 Naples, Italy
    Proc Natl Acad Sci U S A 102:904-8. 2005
    ..These data collectively support the critical role for eNOS in regulating the magnitude of the acute inflammatory response and show that eNOS is critical for regulating microcirculatory endothelial barrier function in vivo...