A Capasso

Summary

Affiliation: Via Ponte Don Melillo
Country: Italy

Publications

  1. ncbi Beta-endorphin fragments (DT gamma E and DE gamma E) reduce opiate withdrawal in guinea pig ileum
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 26:313-9. 2002
  2. ncbi Antioxidant action and therapeutic efficacy of Allium sativum L
    Anna Capasso
    Department of Pharmacy, University of Salerno, Via Ponte Don Melillo, Fisciano, Salerno 84084, Italy
    Molecules 18:690-700. 2013
  3. ncbi Role of lipid rafts/caveolae in the anticancer effect of endocannabinoids
    Claudia Grimaldi
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, 84084 Fisciano, Italy
    Mini Rev Med Chem 12:1119-26. 2012
  4. ncbi Vinorelbine in cancer therapy
    Anna Capasso
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy
    Curr Drug Targets 13:1065-71. 2012
  5. ncbi Methisergide selective inhibition of opioid acute physical dependence in isolated tissues
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Salerno, Italy
    Med Chem 4:309-12. 2008
  6. ncbi Functional interference of dexamethasone on some morphine effects: hypothesis for the steroid-opioid interaction
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Recent Pat CNS Drug Discov 3:138-50. 2008
  7. ncbi Glucocorticoids involvement in the control of CNS excitability
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Recent Pat CNS Drug Discov 2:155-65. 2007
  8. ncbi In vitro binding receptors study by Valeriana adscendens, Iresine herbstii and Brugmansia arborea extracts
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Med Chem 3:599-604. 2007
  9. ncbi Bioactivity of new mu and delta opioid peptides
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo 84084 Fisciano, Italy
    Med Chem 3:480-7. 2007
  10. ncbi The effect of flavonol glycosides on opiate withdrawal
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084, Fisciano, Salerno, Italia
    Med Chem 3:327-31. 2007

Collaborators

Detail Information

Publications48

  1. ncbi Beta-endorphin fragments (DT gamma E and DE gamma E) reduce opiate withdrawal in guinea pig ileum
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 26:313-9. 2002
    ....
  2. ncbi Antioxidant action and therapeutic efficacy of Allium sativum L
    Anna Capasso
    Department of Pharmacy, University of Salerno, Via Ponte Don Melillo, Fisciano, Salerno 84084, Italy
    Molecules 18:690-700. 2013
    ..The aim of this review was to understand the mechanism of antioxidant action and therapeutic efficacy of garlic...
  3. ncbi Role of lipid rafts/caveolae in the anticancer effect of endocannabinoids
    Claudia Grimaldi
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, 84084 Fisciano, Italy
    Mini Rev Med Chem 12:1119-26. 2012
    ..Also, we report the more recent developments of endocannabinoids in cancer drug discovery...
  4. ncbi Vinorelbine in cancer therapy
    Anna Capasso
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy
    Curr Drug Targets 13:1065-71. 2012
    ..The aim of this review is to examine the mechanism of the inhibition of cell proliferation by Vinorelbine and its efficacy in breast cancer patients in phase II studies...
  5. ncbi Methisergide selective inhibition of opioid acute physical dependence in isolated tissues
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Salerno, Italy
    Med Chem 4:309-12. 2008
    ..The results of the present study confirm an important functional interaction between the serotoninergic and opioid system...
  6. ncbi Functional interference of dexamethasone on some morphine effects: hypothesis for the steroid-opioid interaction
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Recent Pat CNS Drug Discov 3:138-50. 2008
    ..c.v. administration, strongly confirm a central site for DEX and RU 38486 action as well as the use of different genetic strains may provide a useful approach for studying DEX-morphine analgesia interaction...
  7. ncbi Glucocorticoids involvement in the control of CNS excitability
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Recent Pat CNS Drug Discov 2:155-65. 2007
    ..The patents related to psychostimulant agent and glucocorticoids are also discussed in this article...
  8. ncbi In vitro binding receptors study by Valeriana adscendens, Iresine herbstii and Brugmansia arborea extracts
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Med Chem 3:599-604. 2007
    ..The results of our experiments indicate that V. adscendens, Iresine herbstii and Brugmansia arborea were able to interact with the central 5-HT receptors thus confirming their ritual use...
  9. ncbi Bioactivity of new mu and delta opioid peptides
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo 84084 Fisciano, Italy
    Med Chem 3:480-7. 2007
    ....
  10. ncbi The effect of flavonol glycosides on opiate withdrawal
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084, Fisciano, Salerno, Italia
    Med Chem 3:327-31. 2007
    ..The results of the present study indicate that flavonol glycosides were able to produce significant influence on the opiate withdrawal in vitro and these compounds were able to exert their effects both at micro and k opioid agonists...
  11. ncbi The involvement of prostaglandins and nitric oxide in the development of brain excitability: a relationship study
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Curr Med Chem 15:2518-26. 2008
    ..These results provide a strong evidence that both PGs and NO may play a significant role in the development of brain excitability...
  12. ncbi Pharmacological profile of SSRIs and SNRIs in the treatment of eating disorders
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Italy
    Curr Clin Pharmacol 4:78-83. 2009
    ....
  13. ncbi Comparison with naloxone of two dynorphin A analogues with K- and delta-opioid antagonist activity
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, via Ponte Don Melillo 84084 Fisciano Salerno, Italy
    Med Chem 5:1-6. 2009
    ..The results of our experiments indicate that both peptide A (k receptor opiod antagonist) and peptide B (alpha receptor opioid antagonist) showed an antagonistic activity higher than naloxone...
  14. ncbi Recent clinical aspects of eating disorders
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, via Ponte Don Melillo 84084 Fisciano Salerno, Italy
    Rev Recent Clin Trials 4:63-9. 2009
    ..Additionally, mood stabilizers (lithium), anxiolytics, serotonin and noradrenalin reuptake inhibitors and antipsychotic drugs are often used in the treatment of ED...
  15. ncbi Beta-endorphin fragments DTgammaE and DEgammaE reduced morphine inhibition of electrically-induced contractions and opiate withdrawal
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Salerno, Italy
    Med Chem 5:165-70. 2009
    ..C. of guinea-pig ileum thus confirming an important functional interaction between gamma-endorphin derivatives and opioid system...
  16. ncbi Functional interaction between purinergic system and opioid withdrawal: in vitro evidence
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Curr Drug Saf 4:97-102. 2009
    ....
  17. ncbi Anticonvulsant activity of new GABA prodrugs
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italia
    Med Chem 5:343-52. 2009
    ..Furthermore, since these compounds are able to act after systemic administration, our data suggest that these new GABA mimetic drug cross the blood-brain barrier...
  18. ncbi Duloxetine in the treatment of depression: an overview
    Francesco Monteleone
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano Salerno Italy
    Cent Nerv Syst Agents Med Chem 11:174-83. 2011
    ..These characteristics make Duloxetine the most effective therapeutic choice to improve both psychological and somatic symptoms of depression in order to get higher rates of symptomatic remission on depressive episodes...
  19. ncbi Efficacy and tolerability of vinorelbine in the cancer therapy
    Giuseppina Galano
    Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
    Curr Drug Saf 6:185-93. 2011
    ..The aim of this review is 1) to explore the efficacy and tolerability of VNR in cancer therapy and 2) to examine the more recent approaches to improve the efficacy and tolerability of VNR in cancer therapy...
  20. ncbi The effect of isoquinoline alkaloids on opiate withdrawal
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084, Italy
    Curr Med Chem 13:807-12. 2006
    ....
  21. ncbi New protopine alkaloids from Aristolochia constricta reduce morphine withdrawal in vitro
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo di Fisciano, Salerno, 84084 Italy
    Phytother Res 14:653-5. 2000
    ..The results of the present study suggest that these new protopine alkaloids may be potential anti-addictive agents...
  22. ncbi Flavonol glycosides from Aristeguietia discolor reduce morphine withdrawal in vitro
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Phytother Res 14:538-40. 2000
    ..The results of the present paper suggest that flavonol glycosides from Aristeguietia discolor may play an important role in the control of morphine withdrawal...
  23. ncbi Effect of somatostatin and its antagonist on morphine analgesia in mice
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Zhongguo Yao Li Xue Bao 20:1079-82. 1999
    ..To study the effects of somatostatin (SST) and its antagonist cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr [Bzl]) (SSA) on morphine-induced analgesia...
  24. ncbi Clonidine-induced antinociception and locomotor hypoactivity are reduced by dexamethasone in mice
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Italy
    J Pharm Pharmacol 53:351-60. 2001
    ....
  25. ncbi Arachidonic acid and its metabolites are involved in the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Fisciano, Italia
    J Pharm Pharmacol 53:883-8. 2001
    ..These results indicate that both dexamethasone and indometacin significantly reduce the S&W of DBA/2J mice, suggesting a possible involvement of arachidonic acid and its metabolites in the development of brain excitability...
  26. ncbi Involvement of nuclear factor-kB in the expression of opiate withdrawal
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 25:1259-68. 2001
    ..4. The results of the present study indicate that NF-kB is involved in the expression of opiate withdrawal thus extending and explaining previous papers performed with dexamethasone and selective arachidonic acid metabolites inhibitors...
  27. ncbi Effects of cysteamine on nociception in mice
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084 Fisciano, Salerno, Italy
    Acta Pharmacol Sin 22:603-8. 2001
    ..The present study was carried to study the effects of cysteamine on nociception in mice...
  28. ncbi Purinoreceptors are involved in the control of acute morphine withdrawal
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Italia
    Life Sci 69:2179-88. 2001
    ....
  29. ncbi Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Italia
    Life Sci 66:873-83. 2000
    ....
  30. ncbi Nitric oxide is involved in the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italia
    J Pharm Pharmacol 55:1115-9. 2003
    ..These results provide evidence that NO may play a significant role in the development of brain excitability...
  31. ncbi Petrosaspongiolide M reduces morphine withdrawal in vitro
    Anna Capasso
    Dipartimento di Scienze Farmaceutiche, Via Ponte Don Melillo, Universita degli Studi di Salerno, 84084 Fisciano SA, Salerno, Italy
    Life Sci 73:611-6. 2003
    ..PM treatment 1 x 10(-8), 5 x 10(-8), 1 x 10(-7) M was able to reduce morphine withdrawal. These results suggest that PM effect in this in vitro model of opiate withdrawal may be due to extracellular type II PLA(2) inhibition...
  32. ncbi Alpha2-adrenoceptor antagonist SL 84.0418 reduces the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 27:141-5. 2003
    ..The present results indicate that SL 84.0418 administration induces significant reduction on S and W of DBA/2J mice suggesting a possible involvement of noradrenergic system in the development of S and W of DBA/2J mice...
  33. ncbi Dexamethasone reduces morphine-induced Straub reaction in mice
    Anna Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Italy
    J Pharm Pharmacol 54:983-7. 2002
    ..The ability of cycloheximide and RU-38486 to block dexamethasone's effects indicates that the steroid's interference with morphine-mediated straub reaction involves a protein-synthesis-dependent mechanism via glucocorticoid receptors...
  34. ncbi The role of nitric oxide in the development of opioid withdrawal induced by naloxone after acute treatment with mu- and kappa-opioid receptor agonists
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Italy
    Eur J Pharmacol 359:127-31. 1998
    ..These results provide evidence that NO has a role in the development of opioid withdrawal and that mu- or kappa-opioid receptors are involved...
  35. ncbi Guinea-pigs treated with beta-endorphin fragments DTgammaE and DEgammaE exhibit reduced morphine inhibition of electrically-induced contractions
    A Capasso
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Italy
    Prog Neuropsychopharmacol Biol Psychiatry 24:51-9. 2000
    ..C. of guinea-pig ileum thus confirming an important functional interaction between gamma-endorphin derivatives and opioid system...
  36. ncbi Further studies on the involvement of the arachidonic acid cascade in the acute dependence produced by mu, kappa and delta opioid agonists in isolated tissues
    A Capasso
    Department of Pharmaceutical Sciences, University of Salerno, Italy
    Neuropharmacology 38:871-7. 1999
    ....
  37. ncbi Saponins from the roots of Zygophyllum gaetulum and their effects on electrically-stimulated guinea-pig ileum
    R Aquino
    Dipartimento di Scienze Farmaceutiche, , Fisciano, Salerno, Italy
    Phytochemistry 56:393-8. 2001
    ..The structure of compound (1) was determined, using 1D and 2D NMR techniques...
  38. ncbi Elderly patients with migraine: an open-label study on prophylaxis therapy with levetiracetam
    V Pizza
    Neurophysiopatology Unit, S Luca Hospital, Vallo della Lucania SA, Italy
    Cent Nerv Syst Agents Med Chem 11:31-4. 2011
    ..In our study levetiracetam showed a good efficacy in frequency and intensity reduction of headache attack and showed a very good tolerability despite all elderly patients took drugs for concomitant diseases...
  39. ncbi Pain and child: a translational hypothesis on the pathophysiology of a mild type-2 diabetes model
    S Loizzo
    Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanita, Roma, Italy
    Endocr Metab Immune Disord Drug Targets 11:1-7. 2011
    ..opioid) endogenous brain receptors and/or neuromediators alteration...
  40. ncbi Phytochemical and pharmacological studies of Guettarda acreana
    A Capasso
    UMSA, Universidad Mayor de San Andres, La Paz, Bolivia
    Planta Med 64:348-52. 1998
    ....
  41. ncbi Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination
    A Capasso
    1st Department of Pharmaceutical Sciences, University of Salerno, Italy
    Phytomedicine 12:39-45. 2005
    ..Due to a synergism of both extracts, simultaneously administered the pharmacologically registered effect in both in vivo experiments was found to be superior over the sum of the single separately administered extracts...
  42. ncbi Synthesis and cytotoxic activity of new β-carboline derivatives
    A Peduto
    Dipartimento di Scienze Farmaceutiche, Universita di Salerno, Via Ponte Don Melillo, 84084 Fisciano SA, Italy
    Mini Rev Med Chem 11:486-91. 2011
    ..Compound X was found to be the most potent one with IC50 value of 8.0 µM; this suggests further studies with models of prostate cancer...
  43. ncbi The involvement of xanthohumol in the expression of annexin in human malignant glioblastoma cells
    M Festa
    University of Salerno, Department of Pharmacy, Italy
    Open Biochem J 7:1-10. 2013
    ..This study shows a possible role of ANXA1 in maintenance of brain homeostasis and may lead to novel therapeutic approaches for neuro-inflammatory diseases and chemotherapy targets in the treatment of glioblastoma multiforme...
  44. ncbi The endocannabinoid system in the cancer therapy: an overview
    C Grimaldi
    Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano Salerno, Italy
    Curr Med Chem 18:1575-83. 2011
    ..The following review describes our current knowledge on the effects of two of the most studied endocannabinoids (AEA and 2-AG) on various types of tumor and summarizes the possible mechanism of observed antitumor effects...
  45. ncbi Treatment of bulimia nervosa with fluvoxamine: a randomized controlled trial
    W Milano
    Department of Pharmaceutical Sciences, Mental Health Unit, University of Salerno, Naples, Italy
    Adv Ther 22:278-83. 2005
    ..In no case was treatment interrupted because of emergent side effects. These findings support the hypothesis that fluvoxamine is well tolerated and effective in reducing binge-eating crises and purging episodes in patients with BN...
  46. ncbi Neuroinflammation and ageing: current theories and an overview of the data
    Vincenzo Pizza
    Neurophysiopathology Unit, S Luca Hospital, Vallo della Lucania SA, Italy
    Rev Recent Clin Trials 6:189-203. 2011
    ..Despite the fact that in recent years many theories about ageing have been developed, we are still far from a full understanding of the mechanisms underlying the ageing process...
  47. ncbi Xolair in asthma therapy: an overview
    Monica Di Domenico
    Department of Pharmaceutical Science, University of Salerno, I 84084 Fisciano, Salerno, Italy
    Inflamm Allergy Drug Targets 10:2-12. 2011
    ..The aim of this review is 1) to explore the safety and tolerability of Xolair in asthma therapy and 2) to examine recent important developments focusing on treatment strategies of asthma with Xolair...
  48. ncbi Neuroinflamm-aging and neurodegenerative diseases: an overview
    Vincenzo Pizza
    Neurophysiopathology Unit, S Luca Hospital, Vallo della Lucania, Italy
    CNS Neurol Disord Drug Targets 10:621-34. 2011
    ....