Angelo L Vescovi

Summary

Country: Italy

Publications

  1. ncbi Brain tumour stem cells
    Angelo L Vescovi
    Department of Biotechnology and Biosciences, University of Milan Bicocca, Milan 20126, Italy
    Nat Rev Cancer 6:425-36. 2006
  2. ncbi Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells
    A L Vescovi
    National Neurological Institute C Besta, Milan, Italy
    J Neurotrauma 16:689-93. 1999
  3. ncbi Mild hypoxia enhances proliferation and multipotency of human neural stem cells
    Guido Santilli
    Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy
    PLoS ONE 5:e8575. 2010
  4. ncbi Adult neural stem cells
    Rossella Galli
    Stem Cell Research Institute HSR SCRI, DIBI H S Raffaele, Milan, Italy
    Methods Mol Biol 438:67-84. 2008
  5. ncbi Clonal analyses and cryopreservation of neural stem cell cultures
    Angela Gritti
    Telethon Institute for Gene Therapy, DIBIT San Raffaele Scientific Institute, Milan, Italy
    Methods Mol Biol 438:173-84. 2008
  6. ncbi Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking
    Margherita Neri
    aStem Cell Research Institute, San Raffaele Scientific Institute, Milan, Italy
    Stem Cells 26:505-16. 2008
  7. ncbi Unique expression and localization of aquaporin-4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny
    Chiara Cavazzin
    Institute for Stem Cell Research, DIBIT, Fond San Raffaele, Milan, Italy
    Glia 53:167-81. 2006
  8. ncbi Clonal analyses and cryopreservation of neural stem cell cultures
    Angelo L Vescovi
    Institute for Stem Cell Research, Ospedale San Raffaele, Milan, Italy
    Methods Mol Biol 198:115-23. 2002
  9. ncbi Brain cancer stem cells
    Sara G M Piccirillo
    Department of Biosciences and Biotechnology, University of Milan Bicocca, Piazza della Scienza 2, Building U3, 20126 Milan, Italy
    J Mol Med (Berl) 87:1087-95. 2009
  10. ncbi Inorganic mercury changes the fate of murine CNS stem cells
    Sabrina Cedrola
    Department of General Physiology and Biochemistry, Section of General Pathology, Celoria 26, Milan, Italy
    FASEB J 17:869-71. 2003

Collaborators

Detail Information

Publications22

  1. ncbi Brain tumour stem cells
    Angelo L Vescovi
    Department of Biotechnology and Biosciences, University of Milan Bicocca, Milan 20126, Italy
    Nat Rev Cancer 6:425-36. 2006
    ..The emerging hypothesis is that alterations in the cellular and genetic mechanisms that control adult neurogenesis might contribute to brain tumorigenesis, thereby allowing the identification of new therapeutic strategies...
  2. ncbi Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells
    A L Vescovi
    National Neurological Institute C Besta, Milan, Italy
    J Neurotrauma 16:689-93. 1999
    ....
  3. ncbi Mild hypoxia enhances proliferation and multipotency of human neural stem cells
    Guido Santilli
    Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy
    PLoS ONE 5:e8575. 2010
    ..In the central nervous system, physiological concentrations of oxygen range from 0.55 to 8% oxygen. In particular, in the in the subventricular zone niche area, it's estimated to be 2.5 to 3%...
  4. ncbi Adult neural stem cells
    Rossella Galli
    Stem Cell Research Institute HSR SCRI, DIBI H S Raffaele, Milan, Italy
    Methods Mol Biol 438:67-84. 2008
    ..The proper application of this method to the cells allows the establishment of long-term expanding stable NSC lines, starting from different neural tissues as the adult rodent CNS and human brain tumor specimens...
  5. ncbi Clonal analyses and cryopreservation of neural stem cell cultures
    Angela Gritti
    Telethon Institute for Gene Therapy, DIBIT San Raffaele Scientific Institute, Milan, Italy
    Methods Mol Biol 438:173-84. 2008
    ..We illustrate and discuss methods for the isolation, propagation, cryopreservation, and functional characterization of NSCs, focusing on the essential issue of their clonogenic capacity...
  6. ncbi Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking
    Margherita Neri
    aStem Cell Research Institute, San Raffaele Scientific Institute, Milan, Italy
    Stem Cells 26:505-16. 2008
    ....
  7. ncbi Unique expression and localization of aquaporin-4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny
    Chiara Cavazzin
    Institute for Stem Cell Research, DIBIT, Fond San Raffaele, Milan, Italy
    Glia 53:167-81. 2006
    ..We provide a reliable and standardized in vitro experimental model to perform functional studies as well as toxicological and pharmacological screenings...
  8. ncbi Clonal analyses and cryopreservation of neural stem cell cultures
    Angelo L Vescovi
    Institute for Stem Cell Research, Ospedale San Raffaele, Milan, Italy
    Methods Mol Biol 198:115-23. 2002
  9. ncbi Brain cancer stem cells
    Sara G M Piccirillo
    Department of Biosciences and Biotechnology, University of Milan Bicocca, Piazza della Scienza 2, Building U3, 20126 Milan, Italy
    J Mol Med (Berl) 87:1087-95. 2009
    ..This review includes a summary review on brain cancer cells and their usefulness as emerging targets in cancer cell therapy...
  10. ncbi Inorganic mercury changes the fate of murine CNS stem cells
    Sabrina Cedrola
    Department of General Physiology and Biochemistry, Section of General Pathology, Celoria 26, Milan, Italy
    FASEB J 17:869-71. 2003
    ..These results demonstrate that inorganic mercury produces toxicity in the ANSC-derived neuronal population and affects the biological properties of the glial-derived population...
  11. ncbi Differentiated human neural stem cells: a new ex vivo model to study HHV-6 infection of the central nervous system
    Lidia De Filippis
    Stem Cell Research Institute, DIBIT, San Raffaele Scientific Institute 20132 Milan, Milan, Italy
    J Clin Virol 37:S27-32. 2006
    ..CONCLUSION: These results demonstrate that hNSC may provide a physiologically relevant model to investigate the pathogenic role of HHV-6 in central nervous system disorders...
  12. ncbi Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system
    Rossella Galli
    Stem Cell Research Institute, H S Raffaele, Via Olgettina 58, Milan, I 20132, Italy
    Development 129:1633-44. 2002
    ..Rather, when Emx2 expression is abolished, the frequency of symmetric divisions that generate two stem cells increases, whereas it decreases when Emx2 expression is enhanced...
  13. ncbi A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes
    Lidia De Filippis
    Department of Biotechnologies, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Stem Cells 25:2312-21. 2007
    ....
  14. ncbi Adult neural stem cells: plasticity and developmental potential
    Angela Gritti
    Institute for Stem Cell Research, DIBIT, S Raffaele Hospital, Via Olgettina 58, Milan, Italy
    J Physiol Paris 96:81-90. 2002
    ....
  15. ncbi Brain tumour stem cells: possibilities of new therapeutic strategies
    Sara G M Piccirillo
    University of Milan, Department of Biotechnology and Biosciences, Bicocca and Stemgen, SPA, Milan, Italy
    Expert Opin Biol Ther 7:1129-35. 2007
    ....
  16. ncbi The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas
    Elena Binda
    Department of Biotechnology and Biosciences, University of Milan Bicocca, 20126 Milan, Italy
    Cancer Cell 22:765-80. 2012
    ..Infusion of ephrinA1-Fc into intracranial xenografts elicited strong tumor-suppressing effects, suggestive of therapeutic applications...
  17. ncbi Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
    Eli E Bar
    Johns Hopkins University School of Medicine, Department of Pathology, 720 Rutland Avenue, Ross Building 558, Baltimore, Maryland 21205, USA
    Stem Cells 25:2524-33. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  18. ncbi Ground-breaking stem-cell work has been reproduced
    Angelo L Vescovi
    Nature 447:259. 2007
  19. ncbi Defining a developmental path to neural fate by global expression profiling of mouse embryonic stem cells and adult neural stem/progenitor cells
    Kazuhiro Aiba
    Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
    Stem Cells 24:889-95. 2006
    ..We suggest that this PC1 defines a path to neural fate, providing a scale for the degree of commitment/differentiation...
  20. ncbi Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
    Stefano Pluchino
    Neuroimmunology Unit-DIBIT, San Raffaele Hospital, Via Olgettina 58, 20132 Milano, Italy
    Nature 422:688-94. 2003
    ..Thus, adult neural precursor cells promote multifocal remyelination and functional recovery after intravenous or intrathecal injection in a chronic model of multiple sclerosis...
  21. ncbi Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents
    Angela Gritti
    Institute for Stem Cell Research, Department of Biotechnology, San Raffaele Hospital, 20132 Milan, Italy
    J Neurosci 22:437-45. 2002
    ..These findings demonstrate that stem cells are not confined to the forebrain periventricular region and indicate that stem cells endowed with different functional characteristics occur at different levels of the SVZ-RE pathway...
  22. ncbi Systematic studies of a self-assembling peptide nanofiber scaffold with other scaffolds
    Fabrizio Gelain
    Center for Biomedical Engineering NE47 379, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    J Nanosci Nanotechnol 7:424-34. 2007
    ....