Massimo Zerani

Summary

Affiliation: University of Camerino
Country: Italy

Publications

  1. ncbi request reprint Immunopresence and functional activity of prostaglandin-endoperoxide synthases and nitric oxide synthases in bovine corpora lutea during diestrus
    Massimo Zerani
    Universita di Camerino, Matelica, Italy
    Folia Morphol (Warsz) 72:36-40. 2013
  2. doi request reprint Evidence for a luteotropic role of peroxisome proliferator-activated receptor gamma: expression and in vitro effects on enzymatic and hormonal activities in corpora lutea of pseudopregnant rabbits
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 88:62. 2013
  3. doi request reprint Gonadotropin-releasing hormone 1 directly affects corpora lutea lifespan in Mediterranean buffalo (Bubalus bubalis) during diestrus: presence and in vitro effects on enzymatic and hormonal activities
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 87:45. 2012
  4. ncbi request reprint Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea
    Massimo Zerani
    Dipartimento di Biologia Molecolare, Cellulare e Animale, Universita di Camerino, via F Camerini 1, 62032 Camerino, Italy
    J Endocrinol 183:279-88. 2004
  5. doi request reprint In vitro effects of gonadotropin-releasing hormone (GnRH) on Leydig cells of adult alpaca (Lama pacos) testis: GnRH receptor immunolocalization, testosterone and prostaglandin synthesis, and cyclooxygenase activities
    M Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, I 62024 Matelica, Italy
    Domest Anim Endocrinol 40:51-9. 2011
  6. ncbi request reprint Leptin receptor expression and in vitro leptin actions on prostaglandin release and nitric oxide synthase activity in the rabbit oviduct
    M Zerani
    Dipartimento di Biologia Molecolare, Cellulare e Animale, Universita di Camerino, via F Camerini 1, 62032 Camerino, Italy
    J Endocrinol 185:319-25. 2005
  7. doi request reprint Expression of type I GNRH receptor and in vivo and in vitro GNRH-I effects in corpora lutea of pseudopregnant rabbits
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, 62024 Matelica, Italy
    J Endocrinol 207:289-300. 2010
  8. doi request reprint Immunopresence and enzymatic activity of nitric oxide synthases, cyclooxygenases and PGE2-9-ketoreductase and in vitro production of PGF2α, PGE2 and testosterone in the testis of adult and prepubertal alpaca (Lama pacos)
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Italy
    Gen Comp Endocrinol 171:381-8. 2011
  9. doi request reprint In vivo chronic and in vitro acute effects of di(2-ethylhexyl) phthalate on pseudopregnant rabbit corpora lutea: possible involvement of peroxisome proliferator-activated receptor gamma
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 90:41. 2014
  10. doi request reprint Aglepristone (RU534) effects on luteal function of pseudopregnant rabbits: steroid receptors, enzymatic activities, and hormone productions in corpus luteum and uterus
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Anim Reprod Sci 138:118-32. 2013

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Immunopresence and functional activity of prostaglandin-endoperoxide synthases and nitric oxide synthases in bovine corpora lutea during diestrus
    Massimo Zerani
    Universita di Camerino, Matelica, Italy
    Folia Morphol (Warsz) 72:36-40. 2013
    ..These results support the idea that PTGSs and NOSs regulate the bovine CL life span mainly during the transition from the luteotrophic to the luteolytic phase...
  2. doi request reprint Evidence for a luteotropic role of peroxisome proliferator-activated receptor gamma: expression and in vitro effects on enzymatic and hormonal activities in corpora lutea of pseudopregnant rabbits
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 88:62. 2013
    ..These results indicate that PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 down-regulation and 3beta-HSD up-regulation, with a consequent PGF2alpha decrease and progesterone increase...
  3. doi request reprint Gonadotropin-releasing hormone 1 directly affects corpora lutea lifespan in Mediterranean buffalo (Bubalus bubalis) during diestrus: presence and in vitro effects on enzymatic and hormonal activities
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 87:45. 2012
    ..Additionally, GNRH directly down-regulates corpora lutea progesterone release, with the concomitant increases of PGF2alpha production and PTGS2 and PGE2-9-K enzymatic activities...
  4. ncbi request reprint Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea
    Massimo Zerani
    Dipartimento di Biologia Molecolare, Cellulare e Animale, Universita di Camerino, via F Camerini 1, 62032 Camerino, Italy
    J Endocrinol 183:279-88. 2004
    ..Leptin used the JAK pathway in increasing PGF2alpha, and MAPK and cAMP-specific PDE in decreasing progesterone. This study supports a permissive luteolytic role for leptin in rabbit CL...
  5. doi request reprint In vitro effects of gonadotropin-releasing hormone (GnRH) on Leydig cells of adult alpaca (Lama pacos) testis: GnRH receptor immunolocalization, testosterone and prostaglandin synthesis, and cyclooxygenase activities
    M Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, I 62024 Matelica, Italy
    Domest Anim Endocrinol 40:51-9. 2011
    ..These data suggest that GnRH directly up-regulates testosterone production in Leydig cells of adult alpaca testis with a postreceptorial mechanism that involves PLC, COX1, and PGF(2α)...
  6. ncbi request reprint Leptin receptor expression and in vitro leptin actions on prostaglandin release and nitric oxide synthase activity in the rabbit oviduct
    M Zerani
    Dipartimento di Biologia Molecolare, Cellulare e Animale, Universita di Camerino, via F Camerini 1, 62032 Camerino, Italy
    J Endocrinol 185:319-25. 2005
    ..This study suggests that the oviduct could be a potential target for endocrine regulation by leptin, whose circulating levels may act as a metabolic signal modulating oviductal PG release through mediation of the NOS/NO system...
  7. doi request reprint Expression of type I GNRH receptor and in vivo and in vitro GNRH-I effects in corpora lutea of pseudopregnant rabbits
    Massimo Zerani
    Scuola di Scienze mediche veterinarie, Universita di Camerino, 62024 Matelica, Italy
    J Endocrinol 207:289-300. 2010
    ....
  8. doi request reprint Immunopresence and enzymatic activity of nitric oxide synthases, cyclooxygenases and PGE2-9-ketoreductase and in vitro production of PGF2α, PGE2 and testosterone in the testis of adult and prepubertal alpaca (Lama pacos)
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Italy
    Gen Comp Endocrinol 171:381-8. 2011
    ..Taken together, the data on COX2, i-NOS and PGE2 led us to hypothesize that development in prepubertal male reproductive tissues utilizes a mechanism similar to that of inflammation...
  9. doi request reprint In vivo chronic and in vitro acute effects of di(2-ethylhexyl) phthalate on pseudopregnant rabbit corpora lutea: possible involvement of peroxisome proliferator-activated receptor gamma
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Biol Reprod 90:41. 2014
    ....
  10. doi request reprint Aglepristone (RU534) effects on luteal function of pseudopregnant rabbits: steroid receptors, enzymatic activities, and hormone productions in corpus luteum and uterus
    Francesco Parillo
    Scuola di Scienze mediche veterinarie, Universita di Camerino, Matelica, Italy
    Anim Reprod Sci 138:118-32. 2013
    ..In conclusion, these data on aglepristone effects suggest that progesterone has a regulatory role on luteal function through direct and uterine-mediated mechanisms in pseudopregnant rabbits...
  11. ncbi request reprint Pituitary adenylate cyclase-activating polypeptide induces testicular testosterone synthesis through PGE(2) mediation in crested newt, Triturus carnifex
    Anna Gobbetti
    Department of Molecular, Cellular and Animal Biology, University of Camerino, Camerino, Italy
    J Exp Zool 293:73-80. 2002
    ..These in vitro results suggest that, in newt testis, PACAP 38 acts on PLC, inducing the increase of PGE(2) which, in turn, acting on AC, increases AR activity with the consequent estradiol-17 beta increase and testosterone decrease...
  12. ncbi request reprint Intraluteal regulation of prostaglandin F2 alpha-induced prostaglandin biosynthesis in pseudopregnant rabbits
    M Zerani
    Dipartimento di Biologia Molecolare, Cellulare e Animale, Universita di Camerino, via F Camerini 1, Camerino, Italy
    Reproduction 133:1005-16. 2007
    ....
  13. ncbi request reprint In vitro nitric oxide effects on basal and gonadotropin-releasing hormone-induced gonadotropin secretion by pituitary gland of male crested newt (Triturus carnifex) during the annual reproductive cycle
    A Gobbetti
    Department of Molecular, Cellular, and Animal Biology, University of Camerino, 62032 Camerino, Italy
    Biol Reprod 60:1217-23. 1999
    ..These results suggest that basal and GnRH-induced gonadotropin secretion are up-regulated by NO in the pituitary gland of the male Triturus carnifex...
  14. ncbi request reprint Different modulation of aromatase activity in frog testis in vitro by ACE and ANG II
    A Miano
    Department of Molecular, University of Camerino, I 62032 Camerino, Italy
    Am J Physiol 277:R1261-7. 1999
    ..As for prostaglandin production, only ANG II influenced PGF(2alpha). These results suggest a new physiological role of ACE and ANG II in modulating steroidogenesis and prostaglandin production...
  15. ncbi request reprint Hormonal and cellular brain mechanisms regulating the amplexus of male and female water frog (Rana esculenta)
    A Gobbetti
    Department of Molecular, Cellular, and Animal Biology, University of Camerino, Camerino MC, Italy
    J Neuroendocrinol 11:589-96. 1999
    ....
  16. ncbi request reprint Substance P downregulates basal and gonadotropin-releasing hormone-induced gonadotropin in vitro secretion by pituitary gland of crested newt, Triturus carnifex
    A Gobbetti
    Department of Molecular, Cellular, and Animal Biology, University of Camerino, Italy
    J Neuroendocrinol 12:1160-6. 2000
    ..In addition, an antagonist role, through receptor-independent mechanisms, exists between GnRH (upregulation) and SP (downregulation) in the modulation of pituitary...
  17. ncbi request reprint Role of nitric oxide in gonadotropin-releasing hormone-dependent prostaglandin F2 alpha synthesis by frog (Rana esculenta) interrenal gland during post-reproduction
    A Gobbetti
    Department of Molecular, Cellular, and Animal Biology, University of Camerino, Italy
    Prostaglandins Other Lipid Mediat 55:277-90. 1998
    ..This study indicates that NO may be involved in regulation of the R. esculenta post-reproduction through stimulation of PGE2-9-ketoreductase activity in GnRH-dependent PGF2 alpha synthesis by the frog interrenal gland...
  18. pmc Evidence for a dopamine intrinsic direct role in the regulation of the ovary reproductive function: in vitro study on rabbit corpora lutea
    Francesco Parillo
    Scuola di Bioscienze e Medicina veterinaria, Universita di Camerino, Matelica, Italy
    PLoS ONE 9:e104797. 2014
    ..The present data shed new light on the physiological mechanisms regulating luteal activity that might improve our ability to optimize reproductive efficiency in mammal species, including humans. ..
  19. ncbi request reprint Hormonal and metabolic adaptation to fasting: effects on the hypothalamic-pituitary-ovarian axis and reproductive performance of rabbit does
    Gabriele Brecchia
    Dipartimento di Scienze Biopatologiche Veterinarie ed Igiene delle Produzioni Animali e Alimentari, Sezione di Fisiologia, Laboratorio di Biotecnologie, Universita degli Studi di Perugia, Via S Costanzo 4, 06126 Perugia, Italy
    Domest Anim Endocrinol 31:105-22. 2006
    ..9% (P < or = 0.05) and 21.4%, but no difference was found in ovulation rate. In summary, nutritional status of does, as modified by fasting, greatly influenced fertility, metabolic and reproductive hormones...
  20. ncbi request reprint Role of the endothelin-1 system in the luteolytic process of pseudopregnant rabbits
    Cristiano Boiti
    Dipartimento di Scienze Biopatologiche Veterinarie, Sezione di Fisiologia, Laboratorio di Biotecnologie Fisiologiche, Università of Perugia, S Costanzo 4, 06126 Perugia, Italy
    Endocrinology 146:1293-300. 2005
    ..01) throughout the late-luteal stage from d 13 up to d 18. Our data suggest that the luteolytic action of ET-1 may be a result of PGF2alpha synthesis from both luteal and accessory cells, via the COX pathways...
  21. ncbi request reprint Expression patterns of cytokines, p53 and nitric oxide synthase isoenzymes in corpora lutea of pseudopregnant rabbits during spontaneous luteolysis
    Cristiano Boiti
    Dipartimento di Scienze Biopatologiche Veterinarie, Universita di Perugia, S Costanzo 4, 06126 Perugia, Italy
    Reproduction 127:229-38. 2004
    ..Locally, luteal cytokines may be involved in the up-regulation of NOS activity, while downstream NO may inhibit steroroidogenesis and induce expression of p53 gene after removal of the protective action of progesterone...
  22. ncbi request reprint Vasoactive peptides in the luteolytic process activated by PGF2alpha in pseudopregnant rabbits at different luteal stages
    Cristiano Boiti
    Dipartimento di Scienze Biopatologiche ed Igiene delle Produzioni Animali e Alimentari, Sezione di Fisiologia Veterinaria, Laboratorio di Biotecnologie Fisiologiche, Universita degli Studi di Perugia, I 06100 Perugia, Italy
    Biol Reprod 77:156-64. 2007
    ..These findings support the hypothesis that PGF2alpha regulates luteolysis through intraluteal activation of the renin-angiotensin/EDN1 systems in CL that have acquired luteolytic competence...