Research Topics
Species | Umberto VoltaSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
Gut-liver axis: an immune link between celiac disease and primary biliary cirrhosisUmberto Volta
Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Italy
Expert Rev Gastroenterol Hepatol 7:253-61. 2013..Reciprocal screening for both diseases is recommended, as an early diagnosis with the appropriate treatment can improve the outcome of these patients...
Serological tests in gluten sensitivity (nonceliac gluten intolerance)Umberto Volta
Department of Clinical Medicine, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
J Clin Gastroenterol 46:680-5. 2012..To characterize the serological pattern of gluten sensitivity (GS) and to compare it with that found in celiac disease...
Spectrum of gluten-related disorders: consensus on new nomenclature and classificationAnna Sapone
Mucosal Biology Research Center and Center for Celiac Research, University of Maryland School of Medicine, Baltimore, MD 21201, USA
BMC Med 10:13. 2012....
New understanding of gluten sensitivityUmberto Volta
Department of Clinical Medicine, University of Bologna and St Orsola Malpighi Hospital, Via Massarenti 9, Bologna 40138, Italy
Nat Rev Gastroenterol Hepatol 9:295-9. 2012..Further research is necessary to establish the main clinicopathological features of gluten sensitivity, thus enabling physicians to improve their management of the increasing number of patients who are sensitive to dietary gluten...
Deamidated gliadin peptide antibodies as a routine test for celiac disease: a prospective analysisUmberto Volta
Department of Clinical Medicine, University of Bologna, Bologna, Italy
J Clin Gastroenterol 44:186-90. 2010..This study was designed to establish whether deamidated gliadin peptide antibodies (DGP-AGA) could improve the serologic workup for celiac disease (CD)...
Celiac disease: diagnostic criteria in progressU Volta
Department of Clinical Medicine, St Orsola Malpighi University Hospital, Bologna, Italy
Cell Mol Immunol 8:96-102. 2011..In cases with a positive serology but with mild or absent intestinal lesions, the detection of HLA-DQ2 and HLA-DQ8 can help reinforce or exclude the diagnosis of gluten sensitivity...
Usefulness of antibodies to deamidated gliadin peptides in celiac disease diagnosis and follow-upUmberto Volta
Department of Gastroenterology and Internal Medicine, S Orsola Malpighi Hospital, University of Bologna, Via Massarenti, 9, Bologna 40138, Italy
Dig Dis Sci 53:1582-8. 2008..The combined use of tissue transglutaminase and deamidated gliadin peptide antibodies seems to be a very useful tool for celiac disease diagnosis. Moreover, antibodies to deamidated gliadin peptides can be helpful in disease follow-up...
Sensorineural hearing loss and celiac disease: a coincidental findingUmberto Volta
Department of Clinical Medicine, University of Bologna, St Orsola Malpighi Hospital, Bologna, Italy
Can J Gastroenterol 23:531-5. 2009..Celiac disease (CD) can be associated with a variety of extraintestinal manifestations, including neurological diseases. A new neurological correlation has been found between CD and sensorineural hearing loss (SNHL)...
Celiac disease in autoimmune cholestatic liver disordersUmberto Volta
Department of Internal Medicine, Cardioangiology, Hepatology, S. Orsola-Malpighi Policlinic, University of Bologna, Italy
Am J Gastroenterol 97:2609-13. 2002..CONCLUSIONS: The high prevalence of CD (3.5%) in autoimmune cholestasis suggests that serological screening for CD should be routinely performed in such patients by immunoglobulin A endomysial or human tissue transglutaminase antibodies...
Multiple nuclear dots and rim-like/membranous IgG isotypes in primary biliary cirrhosisPaolo Muratori
Department of Clinical Medicine, Alma Mater Studiorum, University of Bologna, Italy
Autoimmunity 42:224-7. 2009..In Italian PBC patients MND and RL/M pattern did not seem to characterize any subgroup of patients with a poorer prognosis...
Prevalence of celiac disease in children with type 1 diabetes mellitus increased in the mid-1990 s: an 18-year longitudinal study based on anti-endomysial antibodiesSilvana Salardi
Departments of Pediatrics, University of Bologna, Via Massarenti 11, 40138 Bologna, Italy
J Pediatr Gastroenterol Nutr 46:612-4. 2008..6%) than before 1994 (3.3%). The rapid change in the risk of CD among Italian diabetic children that occurred in the mid-1990 s could be related to changes in environmental factors, namely, eating habits and viral infections...
Clinical and immunological features of celiac disease in patients with Type 1 diabetes mellitusUmberto Volta
Department of Digestive Diseases and Internal Medicine, S Orsola Malpighi Policlinic, University of Bologna, Bologna, Italy
Expert Rev Gastroenterol Hepatol 5:479-87. 2011..Potential CD cases (especially when asymptomatic) should be kept on a gluten-containing diet with a careful clinical and antibody follow-up, since many of them will not develop villous atrophy...
Old and new serological tests for celiac disease screeningUmberto Volta
Department of Gastroenterology and Internal Medicine, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
Expert Rev Gastroenterol Hepatol 4:31-5. 2010..In summary, although both tests represent a very good tool for identifying celiac patients, tTG antibodies display a higher predictive value than DGP antibodies, and must still be considered the best serological test for CD screening...
Increased prevalence of coeliac disease in autoimmune thyroiditis is restricted to aged patientsGiovanni Ravaglia
Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna 40138, Italy
Exp Gerontol 38:589-95. 2003..In conclusion, prevalence of CD is increased in AT but the association is limited to patients aged 65 years or older. Serological screening including anti-tTG-IgA is recommended in these patients...
Evidence of a genetic basis for the different geographic occurrences of liver/kidney microsomal antibody type 1 in hepatitis CPaolo Muratori
Department of Internal Medicine, Cardioangiology, Hepatology, Policlinico Sant Orsola Malpighi, Bologna, Italy
Dig Dis Sci 52:179-84. 2007..HLA DR11 may be protective against the development of microsomal antibodies in Italian patients, whereas HLA DR4, HLA DR13, and the B8-DR3-DQ2 haplotype may be protective in North American patients...
Recurrent ischemic strokes in a young celiac woman with MTHFR gene mutationElisa Fabbri
Stroke Unit, Department of Internal Medicine, Aging and Nephrological Diseases, University of Bologna, 40138 Bologna, Italy
World J Gastroenterol 18:3472-6. 2012..CD should be kept in mind in the differential diagnosis of ischemic stroke in young patients...
Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via FasRoberto De Giorgio
Department of Internal Medicine and Gastroenterology, Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Bologna, Italy
Gastroenterology 135:601-9. 2008..In this study we tested the hypothesis that sera from a subpopulation of patients with CIP contain autoantibodies that activate autophagy via a Fas-dependent pathway in cultured human neuroblastoma SH-Sy5Y cells...
Anti-ganglioside antibodies in coeliac disease with neurological disordersU Volta
Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Building 11, St Orsola Malpighi Hospital, Via Massarenti, 9, 40138 Bologna, Italy
Dig Liver Dis 38:183-7. 2006..Anti-ganglioside antibodies have been described in sera of coeliac patients with peripheral neuropathy and cerebellar ataxia...
Papillary cancer of thyroid in celiac diseaseUmberto Volta
Department of Internal Medicine, S Orsola Malpighi Hospital, Bologna, Italy
J Clin Gastroenterol 45:e44-6. 2011..Celiac disease (CD) has been established as being associated with several thyroid diseases. However, occurrence of thyroid epithelial cancer in celiac patients has been rarely described...
Growth and adult height in atypical coeliac patients, with or without growth hormone deficiencySilvana Salardi
Department of Pediatrics, University of Bologna, Bologna, Italy
J Pediatr Endocrinol Metab 18:769-75. 2005..To evaluate the effect of a gluten-free diet on growth and adult height, when available, in coeliac children without gastrointestinal symptoms...
Adult coeliac disease diagnosed by endoscopic biopsies in the duodenal bulbEmilio Brocchi
Department of Internal Medicine and Gastroenterology, Cardio Angiology and Hepatology, University of Bologna, Italy
Eur J Gastroenterol Hepatol 17:1413-5. 2005....
Pathogenesis and clinical significance of liver injury in celiac diseaseUmberto Volta
Department of Gastroenterology and Internal Medicine, University of Bologna, S Orsola Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy
Clin Rev Allergy Immunol 36:62-70. 2009....
Epilepsy in coeliac disease: not just a matter of calcificationsLaura Licchetta
Department of Neurological Sciences, University of Bologna, Via Ugo Foscolo 7, 40123 Bologna, Italy
Neurol Sci 32:1069-74. 2011..Our data also confirm the major involvement of the occipital lobe, and minimise both the importance of calcifications in epileptogenesis and folic acid deficit in the development of calcifications...
Anti tissue transglutaminase antibodies as predictors of silent coeliac disease in patients with hypertransaminasaemia of unknown originU Volta
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Hospital, Italy
Dig Liver Dis 33:420-5. 2001..Unexplained hypertransaminasaemia can be regarded as an extraintestinal presentation of coeliac disease...
Anti-actin IgA antibodies in severe coeliac diseaseA Granito
Department of Internal Medicine, Cardioangiology, Hepatology, Alma Mater Studiorum University of Bologna, Policlinico Sant Orsola Malpighi, Bologna, Italy
Clin Exp Immunol 137:386-92. 2004..The disappearance of antimicrofilament IgA after gluten withdrawal predicts the normalization of intestinal mucosa and could be considered a useful tool in the follow-up of severe coeliac disease...
Autoimmune enteropathy and rheumatoid arthritis: a new association in the field of autoimmunityU Volta
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
Dig Liver Dis 38:926-9. 2006..Autoimmune enteropathy should be always ruled out in patients with a villous atrophy unresponsive to a gluten-free diet, autoimmune manifestations and negativity of coeliac disease markers...
Antibodies to filamentous actin (F-actin) in type 1 autoimmune hepatitisA Granito
Department of Internal Medicine, Cardioangiology, and Hepatology, Alma Mater Studiorum, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
J Clin Pathol 59:280-4. 2006....
Coeliac disease in patients with autoimmune thyroiditisU Volta
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Polyclinic, Bologna, Italy
Digestion 64:61-5. 2001..The close association between coeliac disease and autoimmunity prompted us to perform an antibody screening for gluten-sensitive enteropathy in patients with autoimmune thyroid dysfunction...
Clinical findings and anti-neuronal antibodies in coeliac disease with neurological disordersU Volta
Dept of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
Scand J Gastroenterol 37:1276-81. 2002..In a large series of adult coeliac disease patients, we investigated the prevalence of neurological disorders and anti-neuronal antibodies, along with the clinical course...
Splanchnic haemodynamics in patients with coeliac disease: effects of a gluten-free dietD Magalotti
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Policlinico S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Dig Liver Dis 35:262-8. 2003..CONCLUSIONS: Splanchnic haemodynamics is significantly changed in coeliac patients, mainly after a meal. On treatment with a gluten-free diet, both fasting and postprandial haemodynamics became normal...
Anti-Saccharomyces cerevisiae and perinuclear anti-neutrophil cytoplasmic antibodies in coeliac disease before and after gluten-free dietA Granito
Department of Internal Medicine, Alma Mater Studiorum, University of Bologna, Policlinico Sant Orsola Malpighi, 40138 Bologna, Italy
Aliment Pharmacol Ther 21:881-7. 2005..Anti-Saccharomyces cerevisiae and perinuclear anti-neutrophil cytoplasmic autoantibodies are markers of Crohn's disease and ulcerative colitis respectively...
Liver dysfunction in celiac diseaseU Volta
Department of Clinical Medicine, St Orsola Malpighi Polyclinic, University of Bologna, Bologna, Italy
Minerva Med 99:619-29. 2008....
Prevalence of silent coeliac disease in atopicsD Zauli
Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
Dig Liver Dis 32:775-9. 2000..Although atopy is described as one of the most frequently associated conditions, the prevalence of coeliac disease in atopics has not yet been established...
