Umberto Volta

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. doi New understanding of gluten sensitivity
    Umberto Volta
    Department of Clinical Medicine, University of Bologna and St Orsola Malpighi Hospital, Via Massarenti 9, Bologna 40138, Italy
    Nat Rev Gastroenterol Hepatol 9:295-9. 2012
  2. ncbi An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity
    Umberto Volta
    Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    BMC Med 12:85. 2014
  3. doi Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity
    Giacomo Caio
    Department of Medical and Surgical Sciences, St, Orsola Malpighi Hospital, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy
    BMC Gastroenterol 14:26. 2014
  4. doi Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Cell Mol Immunol 10:383-92. 2013
  5. doi Fulminant type 1 autoimmune hepatitis in a recently diagnosed celiac disease patient
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Arch Iran Med 16:683-5. 2013
  6. doi Gut-liver axis: an immune link between celiac disease and primary biliary cirrhosis
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Italy
    Expert Rev Gastroenterol Hepatol 7:253-61. 2013
  7. doi Serological tests in gluten sensitivity (nonceliac gluten intolerance)
    Umberto Volta
    Department of Clinical Medicine, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    J Clin Gastroenterol 46:680-5. 2012
  8. pmc Spectrum of gluten-related disorders: consensus on new nomenclature and classification
    Anna Sapone
    Mucosal Biology Research Center and Center for Celiac Research, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    BMC Med 10:13. 2012
  9. doi Celiac disease: diagnostic criteria in progress
    U Volta
    Department of Clinical Medicine, St Orsola Malpighi University Hospital, Bologna, Italy
    Cell Mol Immunol 8:96-102. 2011
  10. doi Deamidated gliadin peptide antibodies as a routine test for celiac disease: a prospective analysis
    Umberto Volta
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    J Clin Gastroenterol 44:186-90. 2010

Collaborators

Detail Information

Publications42

  1. doi New understanding of gluten sensitivity
    Umberto Volta
    Department of Clinical Medicine, University of Bologna and St Orsola Malpighi Hospital, Via Massarenti 9, Bologna 40138, Italy
    Nat Rev Gastroenterol Hepatol 9:295-9. 2012
    ..Further research is necessary to establish the main clinicopathological features of gluten sensitivity, thus enabling physicians to improve their management of the increasing number of patients who are sensitive to dietary gluten...
  2. ncbi An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity
    Umberto Volta
    Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    BMC Med 12:85. 2014
    ....
  3. doi Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity
    Giacomo Caio
    Department of Medical and Surgical Sciences, St, Orsola Malpighi Hospital, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy
    BMC Gastroenterol 14:26. 2014
    ..This study was designed to characterize the effect of the gluten-free diet on anti-gliadin antibodies of IgG class in patients with non-celiac gluten sensitivity...
  4. doi Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Cell Mol Immunol 10:383-92. 2013
    ..Future research is needed to generate more knowledge regarding non-celiac gluten sensitivity, a condition that has global acceptance but has only a few certainties and many unresolved issues. ..
  5. doi Fulminant type 1 autoimmune hepatitis in a recently diagnosed celiac disease patient
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Arch Iran Med 16:683-5. 2013
    ..At this time, the liver autoantibodies turned to be positive thus confirming the development of a type 1 AIH. The hepatic damage progressed to a late onset liver failure requiring liver transplantation. ..
  6. doi Gut-liver axis: an immune link between celiac disease and primary biliary cirrhosis
    Umberto Volta
    Department of Medical and Surgical Sciences, St Orsola Malpighi Hospital, University of Bologna, Italy
    Expert Rev Gastroenterol Hepatol 7:253-61. 2013
    ..Reciprocal screening for both diseases is recommended, as an early diagnosis with the appropriate treatment can improve the outcome of these patients...
  7. doi Serological tests in gluten sensitivity (nonceliac gluten intolerance)
    Umberto Volta
    Department of Clinical Medicine, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    J Clin Gastroenterol 46:680-5. 2012
    ..To characterize the serological pattern of gluten sensitivity (GS) and to compare it with that found in celiac disease...
  8. pmc Spectrum of gluten-related disorders: consensus on new nomenclature and classification
    Anna Sapone
    Mucosal Biology Research Center and Center for Celiac Research, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    BMC Med 10:13. 2012
    ....
  9. doi Celiac disease: diagnostic criteria in progress
    U Volta
    Department of Clinical Medicine, St Orsola Malpighi University Hospital, Bologna, Italy
    Cell Mol Immunol 8:96-102. 2011
    ..In cases with a positive serology but with mild or absent intestinal lesions, the detection of HLA-DQ2 and HLA-DQ8 can help reinforce or exclude the diagnosis of gluten sensitivity...
  10. doi Deamidated gliadin peptide antibodies as a routine test for celiac disease: a prospective analysis
    Umberto Volta
    Department of Clinical Medicine, University of Bologna, Bologna, Italy
    J Clin Gastroenterol 44:186-90. 2010
    ..This study was designed to establish whether deamidated gliadin peptide antibodies (DGP-AGA) could improve the serologic workup for celiac disease (CD)...
  11. ncbi Usefulness of antibodies to deamidated gliadin peptides in celiac disease diagnosis and follow-up
    Umberto Volta
    Department of Gastroenterology and Internal Medicine, S Orsola Malpighi Hospital, University of Bologna, Via Massarenti, 9, Bologna 40138, Italy
    Dig Dis Sci 53:1582-8. 2008
    ..The combined use of tissue transglutaminase and deamidated gliadin peptide antibodies seems to be a very useful tool for celiac disease diagnosis. Moreover, antibodies to deamidated gliadin peptides can be helpful in disease follow-up...
  12. pmc Sensorineural hearing loss and celiac disease: a coincidental finding
    Umberto Volta
    Department of Clinical Medicine, University of Bologna, St Orsola Malpighi Hospital, Bologna, Italy
    Can J Gastroenterol 23:531-5. 2009
    ..Celiac disease (CD) can be associated with a variety of extraintestinal manifestations, including neurological diseases. A new neurological correlation has been found between CD and sensorineural hearing loss (SNHL)...
  13. doi Prevalence of celiac disease in children with type 1 diabetes mellitus increased in the mid-1990 s: an 18-year longitudinal study based on anti-endomysial antibodies
    Silvana Salardi
    Departments of Pediatrics, University of Bologna, Via Massarenti 11, 40138 Bologna, Italy
    J Pediatr Gastroenterol Nutr 46:612-4. 2008
    ..6%) than before 1994 (3.3%). The rapid change in the risk of CD among Italian diabetic children that occurred in the mid-1990 s could be related to changes in environmental factors, namely, eating habits and viral infections...
  14. ncbi Celiac disease in autoimmune cholestatic liver disorders
    Umberto Volta
    Department of Internal Medicine, Cardioangiology, Hepatology, S Orsola Malpighi Policlinic, University of Bologna, Italy
    Am J Gastroenterol 97:2609-13. 2002
    ....
  15. doi Multiple nuclear dots and rim-like/membranous IgG isotypes in primary biliary cirrhosis
    Paolo Muratori
    Department of Clinical Medicine, Alma Mater Studiorum, University of Bologna, Italy
    Autoimmunity 42:224-7. 2009
    ..In Italian PBC patients MND and RL/M pattern did not seem to characterize any subgroup of patients with a poorer prognosis...
  16. ncbi Nailfold capillaroscopy in primary biliary cirrhosis: a useful tool for the early diagnosis of scleroderma
    Francesco Tovoli
    Department of Medical and Surgical Sciences, University of Bologna, Italy
    J Gastrointestin Liver Dis 23:39-43. 2014
    ..Since studies on the prevalence of early SSc in PBC patients are lacking, our aim was to investigate its hitherto unknown prevalence in a large cohort of PBC patients...
  17. doi Clinical and immunological features of celiac disease in patients with Type 1 diabetes mellitus
    Umberto Volta
    Department of Digestive Diseases and Internal Medicine, S Orsola Malpighi Policlinic, University of Bologna, Bologna, Italy
    Expert Rev Gastroenterol Hepatol 5:479-87. 2011
    ..Potential CD cases (especially when asymptomatic) should be kept on a gluten-containing diet with a careful clinical and antibody follow-up, since many of them will not develop villous atrophy...
  18. ncbi Fibromyalgia and coeliac disease: a media hype or an emerging clinical problem?
    Francesco Tovoli
    Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
    Clin Exp Rheumatol 31:S50-2. 2013
    ..The aim of our study was to verify a possible association between FM and CD, by assessing the prevalence of CD in a cohort of FM patients and vice versa...
  19. ncbi Old and new serological tests for celiac disease screening
    Umberto Volta
    Department of Gastroenterology and Internal Medicine, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Expert Rev Gastroenterol Hepatol 4:31-5. 2010
    ..In summary, although both tests represent a very good tool for identifying celiac patients, tTG antibodies display a higher predictive value than DGP antibodies, and must still be considered the best serological test for CD screening...
  20. ncbi Increased prevalence of coeliac disease in autoimmune thyroiditis is restricted to aged patients
    Giovanni Ravaglia
    Department of Internal Medicine, Cardioangiology and Hepatology, University Hospital S Orsola Malpighi, Via Massarenti, 9, Bologna 40138, Italy
    Exp Gerontol 38:589-95. 2003
    ..In conclusion, prevalence of CD is increased in AT but the association is limited to patients aged 65 years or older. Serological screening including anti-tTG-IgA is recommended in these patients...
  21. ncbi Evidence of a genetic basis for the different geographic occurrences of liver/kidney microsomal antibody type 1 in hepatitis C
    Paolo Muratori
    Department of Internal Medicine, Cardioangiology, Hepatology, Policlinico Sant Orsola Malpighi, Bologna, Italy
    Dig Dis Sci 52:179-84. 2007
    ..HLA DR11 may be protective against the development of microsomal antibodies in Italian patients, whereas HLA DR4, HLA DR13, and the B8-DR3-DQ2 haplotype may be protective in North American patients...
  22. pmc Recurrent ischemic strokes in a young celiac woman with MTHFR gene mutation
    Elisa Fabbri
    Stroke Unit, Department of Internal Medicine, Aging and Nephrological Diseases, University of Bologna, 40138 Bologna, Italy
    World J Gastroenterol 18:3472-6. 2012
    ..CD should be kept in mind in the differential diagnosis of ischemic stroke in young patients...
  23. pmc Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via Fas
    Roberto De Giorgio
    Department of Internal Medicine and Gastroenterology, Centro Unificato di Ricerca BioMedica Applicata, University of Bologna, Bologna, Italy
    Gastroenterology 135:601-9. 2008
    ..In this study we tested the hypothesis that sera from a subpopulation of patients with CIP contain autoantibodies that activate autophagy via a Fas-dependent pathway in cultured human neuroblastoma SH-Sy5Y cells...
  24. ncbi Anti-ganglioside antibodies in coeliac disease with neurological disorders
    U Volta
    Department of Internal Medicine, Cardioangiology and Hepatology, University of Bologna, Building 11, St Orsola Malpighi Hospital, Via Massarenti, 9, 40138 Bologna, Italy
    Dig Liver Dis 38:183-7. 2006
    ..Anti-ganglioside antibodies have been described in sera of coeliac patients with peripheral neuropathy and cerebellar ataxia...
  25. doi Pathogenesis and clinical significance of liver injury in celiac disease
    Umberto Volta
    Department of Gastroenterology and Internal Medicine, University of Bologna, S Orsola Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy
    Clin Rev Allergy Immunol 36:62-70. 2009
    ....
  26. ncbi Low risk of colon cancer in patients with celiac disease
    Umberto Volta
    Department of Medical and Surgical Sciences Digestive Diseases and Internal Medicine, St Orsola Malpighi Hospital, Bologna, Italy
    Scand J Gastroenterol 49:564-8. 2014
    ..In this cohort study, we describe the risk of colon carcinoma in a group of Italian celiac patients...
  27. ncbi A case of leptospirosis simulating colon cancer with liver metastases
    Alessandro Granito
    Dipartimento di Medicina Interna, Policlinico S Orsola Malpighi, Via Massarenti, 9, 40138 Bologna, Italy
    World J Gastroenterol 10:2455-6. 2004
    ..Diagnosis of leptospirosis was considered and confirmed by detection of an elevated titer of antibodies to leptospira. After two mo, biochemical data, CT and colonoscopy were totally normal...
  28. doi Papillary cancer of thyroid in celiac disease
    Umberto Volta
    Department of Internal Medicine, S Orsola Malpighi Hospital, Bologna, Italy
    J Clin Gastroenterol 45:e44-6. 2011
    ..Celiac disease (CD) has been established as being associated with several thyroid diseases. However, occurrence of thyroid epithelial cancer in celiac patients has been rarely described...
  29. ncbi Growth and adult height in atypical coeliac patients, with or without growth hormone deficiency
    Silvana Salardi
    Department of Pediatrics, University of Bologna, Bologna, Italy
    J Pediatr Endocrinol Metab 18:769-75. 2005
    ..To evaluate the effect of a gluten-free diet on growth and adult height, when available, in coeliac children without gastrointestinal symptoms...
  30. ncbi Adult coeliac disease diagnosed by endoscopic biopsies in the duodenal bulb
    Emilio Brocchi
    Department of Internal Medicine and Gastroenterology, Cardio Angiology and Hepatology, University of Bologna, Italy
    Eur J Gastroenterol Hepatol 17:1413-5. 2005
    ....
  31. doi Epilepsy in coeliac disease: not just a matter of calcifications
    Laura Licchetta
    Department of Neurological Sciences, University of Bologna, Via Ugo Foscolo 7, 40123 Bologna, Italy
    Neurol Sci 32:1069-74. 2011
    ..Our data also confirm the major involvement of the occipital lobe, and minimise both the importance of calcifications in epileptogenesis and folic acid deficit in the development of calcifications...
  32. ncbi Coeliac disease in patients with autoimmune thyroiditis
    U Volta
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Polyclinic, Bologna, Italy
    Digestion 64:61-5. 2001
    ..The close association between coeliac disease and autoimmunity prompted us to perform an antibody screening for gluten-sensitive enteropathy in patients with autoimmune thyroid dysfunction...
  33. pmc Antibodies to filamentous actin (F-actin) in type 1 autoimmune hepatitis
    A Granito
    Department of Internal Medicine, Cardioangiology, and Hepatology, Alma Mater Studiorum, University of Bologna, S Orsola Malpighi Hospital, Bologna, Italy
    J Clin Pathol 59:280-4. 2006
    ....
  34. ncbi Autoimmune enteropathy and rheumatoid arthritis: a new association in the field of autoimmunity
    U Volta
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 38:926-9. 2006
    ..Autoimmune enteropathy should be always ruled out in patients with a villous atrophy unresponsive to a gluten-free diet, autoimmune manifestations and negativity of coeliac disease markers...
  35. ncbi Anti tissue transglutaminase antibodies as predictors of silent coeliac disease in patients with hypertransaminasaemia of unknown origin
    U Volta
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, S Orsola Malpighi Hospital, Italy
    Dig Liver Dis 33:420-5. 2001
    ..Unexplained hypertransaminasaemia can be regarded as an extraintestinal presentation of coeliac disease...
  36. pmc Anti-actin IgA antibodies in severe coeliac disease
    A Granito
    Department of Internal Medicine, Cardioangiology, Hepatology, Alma Mater Studiorum University of Bologna, Policlinico Sant Orsola Malpighi, Bologna, Italy
    Clin Exp Immunol 137:386-92. 2004
    ..The disappearance of antimicrofilament IgA after gluten withdrawal predicts the normalization of intestinal mucosa and could be considered a useful tool in the follow-up of severe coeliac disease...
  37. ncbi Liver dysfunction in celiac disease
    U Volta
    Department of Clinical Medicine, St Orsola Malpighi Polyclinic, University of Bologna, Bologna, Italy
    Minerva Med 99:619-29. 2008
    ....
  38. ncbi Splanchnic haemodynamics in patients with coeliac disease: effects of a gluten-free diet
    D Magalotti
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Policlinico S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
    Dig Liver Dis 35:262-8. 2003
    ..Coeliac disease is characterized by structural and functional changes in the small bowel which may also result in haemodynamic changes...
  39. ncbi Anti-Saccharomyces cerevisiae and perinuclear anti-neutrophil cytoplasmic antibodies in coeliac disease before and after gluten-free diet
    A Granito
    Department of Internal Medicine, Alma Mater Studiorum, University of Bologna, Policlinico Sant Orsola Malpighi, 40138 Bologna, Italy
    Aliment Pharmacol Ther 21:881-7. 2005
    ..Anti-Saccharomyces cerevisiae and perinuclear anti-neutrophil cytoplasmic autoantibodies are markers of Crohn's disease and ulcerative colitis respectively...
  40. ncbi Prevalence of silent coeliac disease in atopics
    D Zauli
    Department of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
    Dig Liver Dis 32:775-9. 2000
    ..Although atopy is described as one of the most frequently associated conditions, the prevalence of coeliac disease in atopics has not yet been established...
  41. ncbi Clinical findings and anti-neuronal antibodies in coeliac disease with neurological disorders
    U Volta
    Dept of Internal Medicine, Cardioangiology, Hepatology, University of Bologna, Italy
    Scand J Gastroenterol 37:1276-81. 2002
    ..In a large series of adult coeliac disease patients, we investigated the prevalence of neurological disorders and anti-neuronal antibodies, along with the clinical course...