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Genomes and Genes | Marco VolanteSummaryAffiliation: University of Turin Country: Italy Publications
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Publications
Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasmsMarco Volante
Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Regione Gonzole10, 10043, Orbassano, Torino, Italy
Virchows Arch 451:S61-9. 2007..Moreover, molecular and clinical aspects, which might help to understand their possible histogenesis and biological behavior, will be reviewed...- Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphyMarco Volante
Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Orbassano, Turin, Italy
Mod Pathol 20:1172-82. 2007.... 
Tumor staging but not grading is associated with adverse clinical outcome in neuroendocrine tumors of the appendix: a retrospective clinical pathologic analysis of 138 casesMarco Volante
Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
Am J Surg Pathol 37:606-12. 2013....
Continuous 5-fluorouracil infusion plus long acting octreotide in advanced well-differentiated neuroendocrine carcinomas. A phase II trial of the Piemonte oncology networkMaria P Brizzi
Oncologia Medica, Dipartimento di Scienze Cliniche e Biologiche, Universita di Torino, Azienda Ospedaliera San Luigi, Regione Gonzole, 10, 10043 Orbassano TO, Italy
BMC Cancer 9:388. 2009..A phase II study was designed to test the activity of protracted 5-fluorouracil (5FU) infusion plus long-acting release (LAR) octreotide in patients with neuroendocrine carcinoma...- Clinicopathological study of a series of 92 adrenocortical carcinomas: from a proposal of simplified diagnostic algorithm to prognostic stratificationMarco Volante
Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Turin, Italy
Histopathology 55:535-43. 2009..The aim was to investigate the impact of individual pathological parameters in the diagnosis and prognosis of adrenocortical carcinoma... - RAS mutations are the predominant molecular alteration in poorly differentiated thyroid carcinomas and bear prognostic impactMarco Volante
Department of Clinical and Biological Sciences, San Luigi Hospital, 10043 Orbassano, Italy
J Clin Endocrinol Metab 94:4735-41. 2009..Recently homogeneous diagnostic criteria have been proposed by our group (Turin proposal) that need to be complemented by detailed molecular characterization... - Matrix metalloproteinase type 2 expression in malignant adrenocortical tumors: Diagnostic and prognostic significance in a series of 50 adrenocortical carcinomasMarco Volante
Division of Pathology, Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Orbassano, Torino, Italy
Mod Pathol 19:1563-9. 2006..In addition, a strong metalloproteinase type 2 expression in adrenocortical carcinoma was for the first time recognized as an unfavorable prognostic factor... - Poorly differentiated thyroid carcinoma: diagnostic features and controversial issuesMarco Volante
Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Regione Gonzole 10, 10043, Orbassano, Turin, Italy
Endocr Pathol 19:150-5. 2008..The present paper aims to review the various aspects of this tumor type, from morphology to immunohistochemistry and molecular abnormalities from a practical and daily practice-oriented point of view... - A practical diagnostic approach to solid/trabecular nodules in the thyroidMarco Volante
Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Regione Gonzole 10, Turin, Orbassano, Italy
Endocr Pathol 19:75-81. 2008..A schematic algorithm is presented, which takes into consideration the diagnostic hallmarks of the most relevant entities that enter in the differential diagnosis in solid/trabecular nodules within the thyroid... - Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approachMarco Volante
Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Turin, Italy
Am J Surg Pathol 31:1256-64. 2007..An algorithmic approach was devised for practical use in the diagnosis of this tumor... - Poorly differentiated thyroid carcinoma: 5 years after the 2004 WHO classification of endocrine tumoursMarco Volante
Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Regione Gonzole 10, 10043, Orbassano, Turin, Italy
Endocr Pathol 21:1-6. 2010.... - Increased neuroendocrine cells in resected metastases compared to primary colorectal adenocarcinomasMarco Volante
University of Turin at San Luigi Hospital, Orbassano, Torino, Italy
Virchows Arch 457:521-7. 2010.... - The Weiss score and beyond--histopathology for adrenocortical carcinomaMauro Papotti
Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Regione Gonzole 10, 10043, Orbassano, Turin, Italy
Horm Cancer 2:333-40. 2011..As a complement to the morphological approach, some immunohistochemical markers (such as steroidogenic factor 1) have been proposed as diagnostic and prognostic adjuncts but still lack wide clinical validation... - Caveolin-1 expression in lung carcinoma varies according to tumour histotype and is acquired de novo in brain metastasesPaola Cassoni
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
Histopathology 55:20-7. 2009..To study caveolin-1 (Cav-1) expression in metastatic lung carcinomas... - Epidermal growth factor receptor gene in primary tumor and metastatic sites from non-small cell lung cancerLorenzo Daniele
Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy
J Thorac Oncol 4:684-8. 2009..Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors are capable of reducing brain and adrenal metastases. However, the EGFR status may be discordant between primary NSCLC and the corresponding metastases... - Ghrelin in fetal thyroid and follicular tumors and cell lines: expression and effects on tumor growthMarco Volante
Departments of Pathology, Endocrinology, and Pharmacology, University of Turin, Turin
Am J Pathol 162:645-54. 2003.... - Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatinPaolo Ceppi
University of Turin, Department of Clinical and Biological Sciences, San Luigi Hospital, Regione Gonzole 10, Orbassano, Italy
Mol Cancer Ther 8:3066-74. 2009..The data of this study support further clinical studies aimed to evaluate the efficacy of Src-inhibiting agents in combination with cisplatin in the treatment of NSCLC... - Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumorsPaolo Ceppi
Thoracic Oncology Unit, Pathology Division, Department of Clinical and Biological Sciences, University of Torino, San Luigi Hospital, Torino, Italy
Clin Cancer Res 14:1059-64. 2008..Neuroendocrine tumors (NET) represent potential targets of antifolate agents, but no data on TS expression level in these tumors are currently available... - Epidermal growth factor ligand/receptor loop and downstream signaling activation pattern in completely resected nonsmall cell lung cancerMarco Volante
Department of Clinical and Biological Sciences, University of Turin, Turin, Italy
Cancer 110:1321-8. 2007.... - Galectin-3 and Ki-67 expression in multiglandular parathyroid lesionsEnrico Saggiorato
Section of Endocrinology, University of Turin, Italy
Am J Clin Pathol 126:59-66. 2006.... - Bone sialoprotein is predictive of bone metastases in resectable non-small-cell lung cancer: a retrospective case-control studyMauro Papotti
Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy
J Clin Oncol 24:4818-24. 2006..Currently, there are no predictive or diagnostic markers to identify high-risk patients for metastatic bone dissemination... - Human ASH1 expression in prostate cancer with neuroendocrine differentiationIda Rapa
Division of Pathology, Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Turin, Italy
Mod Pathol 21:700-7. 2008.... - The prognostic role of immunohistochemical chromogranin a expression in prostate cancer patients is significantly modified by androgen-deprivation therapyAlfredo Berruti
Oncologia Medica, Dipartimento di Scienze Cliniche e Biologiche, Universita di Torino, Torino, Italy
Prostate 70:718-26. 2010..This study was undertaken to assess the prognostic role of tissue chromogranin A (CgA) expression in patients addressed to ADT as opposed to those who did not... - Desmocollin-3: a new marker of squamous differentiation in undifferentiated large-cell carcinoma of the lungValentina Monica
Department of Clinical and Biological Sciences, San Luigi Hospital, University of Turin, Torino, Italy
Mod Pathol 22:709-17. 2009.... - Obestatin in human neuroendocrine tissues and tumours: expression and effect on tumour growthMarco Volante
Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Orbassano, Turin, Italy
J Pathol 218:458-66. 2009.... - Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammationRiccarda Granata
Laboratory of Molecular and Cellular Endocrinology, Department of Internal Medicine, University of Turin, Corso Dogliotti 14 10126 Turin, Italy
FASEB J 26:3393-411. 2012..These results provide evidence of a novel role for obestatin in adipocyte function and glucose metabolism and suggest potential therapeutic perspectives in insulin resistance and metabolic dysfunctions... - Somatostatin and somatostatin analogues reduce PDGF-induced endometrial cell proliferation and motilityMarta Annunziata
Laboratory of Molecular and Cellular Endocrinology, Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Hum Reprod 27:2117-29. 2012.... - Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinomaAlfredo Berruti
Department of Clinical and Biological Science, University of Turin, Azienda Ospedaliero Universitaria San Luigi, Regione Gonzole 10, 10043 Orbassano, Italy
Eur J Endocrinol 166:451-8. 2012..There is a strong rationale in the use of antiangiogenic therapy in the management of adrenocortical carcinoma (ACC). Metronomic administration of chemotherapy and antiangiogenic drugs can be synergistic in targeting endothelial cells... - Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lungLuisella Righi
Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Regione Gonzole 10, Orbassano, Turin, Italy
Endocr Relat Cancer 17:977-87. 2010.... - Galectin-3 and HBME-1 expression in oncocytic cell tumors of the thyroidMarco Volante
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
Virchows Arch 445:183-8. 2004.... - Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathwaysSilvia Saviozzi
Genomics and Informatics Unit, University of Torino, Turin, Italy
Cancer Res 69:3390-6. 2009..In conclusion, genes belonging to DNA repair/replication pathways are overexpressed in NSCLC and are associated with a more aggressive phenotype... - Functional role and prognostic significance of CD157 in ovarian carcinomaErika Ortolan
Department of Genetics, Biology and Biochemistry, University of Turin Medical School, Turin, Italy
J Natl Cancer Inst 102:1160-77. 2010..Because CD157 is expressed in mesothelial cells and diapedesis resembles tumor cell migration, we investigated the role of CD157 in ovarian carcinoma... - Co-expression of EGF receptor, TGFalpha and S6 kinase is significantly associated with colorectal carcinomas with distant metastases at diagnosisMarco Tampellini
Division of Medical Oncology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Regione Gonzole 10, 10043, Orbassano, Turin, Italy
Virchows Arch 450:321-8. 2007..4% vs 38.7%; p = 0.02). In agreement with in vitro data, EGFR, TGFalpha and S6K co-expression in human CRC was significantly higher in patients with advanced stage at diagnosis... - Polymerase eta mRNA expression predicts survival of non-small cell lung cancer patients treated with platinum-based chemotherapyPaolo Ceppi
Thoracic Oncology Unit, Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano Torino, Italy
Clin Cancer Res 15:1039-45. 2009..The aim of the present study was to investigate the role of Pol eta mRNA expression levels in non-small cell lung cancer (NSCLC)... - Adrenocortical tumors with myxoid features: a distinct morphologic and phenotypical variant exhibiting malignant behaviorMauro Papotti
Department of Clinical and Biological Sciences, University of Turin at St Luigi Hospital, Orbassano, Torino, Italy
Am J Surg Pathol 34:973-83. 2010.... - Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heartRiccarda Granata
Laboratory of Molecular and Cellular Endocrinology, Department of Internal Medicine, University of Turin, Corso Dogliotti 14, 10126 Turin, Italy
Cardiovasc Res 83:303-12. 2009..We investigated GHRH effects on cardiac myocyte cell survival and the underlying signalling mechanisms... - Mammalian target of rapamycin pathway activation is associated to RET mutation status in medullary thyroid carcinomaIda Rapa
Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, 10043 Orbassano, Turin, Italy
J Clin Endocrinol Metab 96:2146-53. 2011..The genetic pathways involved in medullary thyroid carcinomas (MTC), except for RET mutations, are largely unknown, as is the detailed mapping of proteins activated as a consequence of RET tyrosine kinase phosphorylation... - Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II studyPaola Sperone
Dipartimento di Scienze Cliniche e Biologiche Università di Torino, Orbassano, Italy
Endocr Relat Cancer 17:445-53. 2010..3 (range: 1-43) and 9.8 months (range: 3-73) respectively. Gemcitabine plus metronomic fluoropyrimidines is a well-tolerated and moderately active regimen in heavily pretreated ACC patients... - Basaloid adenocarcinoma. A new variant of pulmonary adenocarcinomaValerio Marci
Department of Pathology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
Virchows Arch 451:729-36. 2007..These findings indicate that a basaloid variant of adenocarcinoma is also existing in the spectrum of basaloid carcinomas of the lung... - Expression of cortistatin and MrgX2, a specific cortistatin receptor, in human neuroendocrine tissues and related tumoursElena Allia
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
J Pathol 207:336-45. 2005.... - Galectin-3 expression in parathyroid carcinoma: immunohistochemical study of 26 casesNicoletta Bergero
Division of Pathology, Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, 10043 Prbassano, Italy
Hum Pathol 36:908-14. 2005..We conclude that Gal-3 immunostaining is a valuable tool to support a diagnosis of PC in highly proliferating (Ki67 >6%) tumors affecting a single parathyroid gland... - Ribonucleotide reductase large subunit (RRM1) gene expression may predict efficacy of adjuvant mitotane in adrenocortical cancerMarco Volante
Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy
Clin Cancer Res 18:3452-61. 2012..Our aim was to evaluate the gene expression of ribonucleotide reductase large subunit 1 (RRM1) and excision repair cross-complementation group 1 (ERCC1) in ACC as potential biomarkers for clinical outcome and response to mitotane... - Oncocytic adrenocortical tumors: diagnostic algorithm and mitochondrial DNA profile in 27 casesEleonora Duregon
Division of Pathology, Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy
Am J Surg Pathol 35:1882-93. 2011.... - Absence of RET gene point mutations in sporadic thyroid C-cell hyperplasiaEnrico Saggiorato
Section of Endocrinology, Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano, Italy
J Mol Diagn 9:214-9. 2007.... - Retrospective evaluation of the outcome of open versus laparoscopic adrenalectomy for stage I and II adrenocortical cancerFrancesco Porpiglia
S C D U Urologia, University of Turin San Luigi Hospital, Turin, Italy
Eur Urol 57:873-8. 2010..Although there is consensus that laparoscopy is the standard of care for the resection of benign adrenal tumours, there is controversy regarding the role of laparoscopy for the resection of adrenocortical cancer (ACC)... - Ghrelin expression in fetal, infant, and adult human lungMarco Volante
Department of Pathology, University of Turin, Turin, Italy
J Histochem Cytochem 50:1013-21. 2002..We conclude that the fetal lung is an additional source of circulating ghrelin, whose functions at the respiratory tract level remain to be clarified... - Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma. A useful marker of invasive growthIda Rapa
Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Orbassano, Torino, Italy
Am J Clin Pathol 125:847-54. 2006.... - Detection and characterization of classical and "uncommon" exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencingLuisella Righi
Divisions of Pathology, University of Torino, Regione Gonzole 10, Torino, Orbassano 10043, Italy
BMC Cancer 13:114. 2013.... - Ghrelin and the endocrine pancreasFabio Broglio
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Ospedale Molinette, Corso Dogliotti 14, 10126 Turin, Italy
Endocrine 22:19-24. 2003..This evidence indicates that the endocrine pancreas plays a role in directly or indirectly modulating ghrelin secretion... - Clinico-pathological features of a series of 11 oncocytic endocrine tumours of the pancreasMarco Volante
Department of Biomedical Sciences and Human Oncology, University of Turin, Via Santena 7, 10126, Turin, and Department of Pathology, Ospedale di Circolo, Varese, Italy
Virchows Arch 448:545-51. 2006.... - Unacylated ghrelin and obestatin increase islet cell mass and prevent diabetes in streptozotocin-treated newborn ratsRiccarda Granata
Division of Endocrinology, Diabetology and Metabolism, Department of Internal Medicine, University of Turin, Turin, Italy
J Mol Endocrinol 45:9-17. 2010..Taken together, our results suggest that in STZ-treated newborn rats, UAG and Ob improve glucose metabolism and preserve islet cell mass, granting a therapeutic potential in medical conditions associated with impaired beta-cell function... - Neuro-endocrine tumours of the lung. A review of relevant pathological and molecular dataLuisella Righi
Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy
Virchows Arch 451:S51-9. 2007..The "molecular classification" of NE tumours should be integrated to morphology, for a better definition of the different histological types and a more appropriate selection of the therapeutic strategy... - Potential applications of molecular biology in neuroendocrine tumorsTommaso Emmer
Department of Biomedical Sciences and Oncology, University of Turin, Turin, Italy
Endocr Pathol 14:319-28. 2003..g., oxytocin and somatostatin receptors) and the development of potent synthetic analogs of such peptides, are opening promising applications in the diagnosis and therapy of endocrine tumors... - p63 expression as a new prognostic marker in Merkel cell carcinomaSofia Asioli
Department of Biomedical Sciences and Human Oncology, University of Turin, Italy
Cancer 110:640-7. 2007..Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin tumor, mostly affecting elderly individuals. The histogenesis of this rare tumor as well as its prognostic criteria are a matter of dispute... - Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantlyFulvia Daffara
Medicina Interna I, A S O San Luigi, Regione Gonzole, 10, 10043 Orbassano, Italy
Endocr Relat Cancer 15:1043-53. 2008..A low-dose monitored regimen of mitotane is tolerable and able to maintain elevated drug concentrations in the long term. Mitotane exerts a complex effect on the endocrine system that may require multiple hormone replacement therapy... - Poorly differentiated carcinomas of the thyroid with trabecular, insular, and solid patterns: a clinicopathologic study of 183 patientsMarco Volante
Department of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
Cancer 100:950-7. 2004..However, a numeric scoring system applied to specific clinicopathologic parameters further may identify three prognostic categories of patients who have significantly different survival rates at 5 years and 10 years... - Anti-angiogenic effect of tamoxifen combined with epirubicin in breast cancer patientsTeresa Mele
Oncologia Medica, Dipartimento di Scienze Cliniche e Biologiche Università di Torino, Azienda Ospedaliera Universitaria San Luigi di Orbassano, Regione Gonzole 10, 10043, Orbassano, Italy
Breast Cancer Res Treat 123:795-804. 2010..02). The addition of tamoxifen to epirubicin resulted in a suppression of a key angiogenic pathway. These data suggest a potential synergism of these two drugs... - Cell membrane reactivity of MIB-1 antibody to Ki67 in human tumors: fact or artifact?Eugenio Leonardo
Division of Pathology, San Luigi Hospital, Orbassano, Torino, Italy
Appl Immunohistochem Mol Morphol 15:220-3. 2007..We conclude that when Ki67 immunohistochemistry is used for diagnostic purposes in a suspected HTT, only MIB-1 clone at room temperature should be employed... - Diagnostic controversies in vascular proliferations of the thyroid glandMauro Papotti
Department of Pathology, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy
Endocr Pathol 19:175-83. 2008.... - 99mTc-MIBI Imaging in the presurgical characterization of thyroid follicular neoplasms: relationship to multidrug resistance protein expressionEnrico Saggiorato
Section of Endocrinology, Division of Internal Medicine, Department of Clinical and Biological Sciences, Gradenigo Hospital, University of Turin, Turin, Italy
J Nucl Med 50:1785-93. 2009..This study also aimed to analyze the relationship between (99m)Tc-MIBI images and P-glycoprotein (P-gp)/multidrug resistance-associated protein-1 (MRP1) immunohistochemical expression... - The pathological diagnosis of neuroendocrine tumors: common questions and tentative answersMarco Volante
Divisions of Pathology, University of Turin at San Luigi Hospital, Orbassano, Torino, Italy
Virchows Arch 458:393-402. 2011..The present paper is an overview of the most frequently asked questions and an attempt to provide practical answers related to NEN diagnosis in the daily pathology work... - Myxoid renal tumor with myoepithelial differentiation mimicking a salivary gland pleomorphic adenoma: description of a caseDonatella Pacchioni
Department of Biomedical Science, University of Turin, Italy
Am J Surg Pathol 31:632-6. 2007..A definitive classification and histogenetic interpretation of this previously unreported tumor type awaits description of further cases showing similar features which, perhaps, as it may happen, went so far unnoticed... - The grey zone between pure (neuro)endocrine and non-(neuro)endocrine tumours: a comment on concepts and classification of mixed exocrine-endocrine neoplasmsMarco Volante
Department of Clinical and Biological Sciences, University of Turin and San Luigi Hospital, Regione Gonzole10, 10043 Orbassano-Torino, Italy
Virchows Arch 449:499-506. 2006..The recognition of MEECs may be of relevance for a targeted therapeutic strategy, foreseeing the use of biotherapies similar to those proposed for pure NE tumours... - Immunohistochemical study of neuroendocrine differentiation in primary glandular lesions and tumors of the urinary bladderEnrico R Bollito
Division of Pathology, San Luigi Gonzaga Hospital, Orbassano, Italy
Anal Quant Cytol Histol 27:218-24. 2005..Neuroendocrine (NE) cells are uncommon in primary adenocarcinoma (AC) and other glandular lesions of the bladder, with no recent study series concerning its significance in differential diagnosis, prognosis or biologic significance... - Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthasePaolo Ceppi
Thoracic Oncology Unit, Department of Clinical and Biological Sciences, University of Turin, San Luigi Hospital, Orbassano, Torino, Italy
Cancer 107:1589-96. 2006..This information may be useful in selecting which patients with NSCLC should receive treatment with TS-inhibiting agents... - E2F-1 transcription factor is overexpressed in oxyphilic thyroid tumorsMarco Volante
Department of Biomedical Sciences and Oncology, University of Turin, Torino, Italy
Mod Pathol 15:1038-43. 2002..In addition, in oxyphilic tumors, more than two thirds of tumor cells express E2F-1, an event possibly linked to proapoptotic rather than proliferative signals in such neoplasms... - Somatostatin receptors and their interest in diagnostic pathologyMarco Volante
Department of Biomedical Sciences, San Luigi Hospital, Orbassano, University of Turin, Turin, Italy
Endocr Pathol 15:275-91. 2004..This is particularly, but not exclusively, the case in the field of neuroendocrine oncology, where sst typing may affect the clinical management of patients with sst-positive tumors... - Prognostic factors of clinical interest in poorly differentiated carcinomas of the thyroidMarco Volante
Department of Biomedical Sciences, San Luigi Hospital, Orbassano, University of Turin, Italy
Endocr Pathol 15:313-7. 2004..Therefore, as also proposed for other thyroid carcinomas (e.g., papillary carcinoma) grading of PD carcinomas on the basis of these latter parameters is encouraged to select those cases with a high risk of poor outcome... - Poorly differentiated carcinoma of the thyroid: validation of the Turin proposal and analysis of IMP3 expressionSofia Asioli
Division of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Mod Pathol 23:1269-78. 2010..Expression of IMP3 appears to be an adverse prognostic factor for poorly differentiated thyroid carcinoma... - Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumorsMarco Volante
Department of Biomedical Sciences and Oncology, University of Turin, I 10126 Torino, Italy
J Clin Endocrinol Metab 87:1300-8. 2002..Expression of GHS-R in some of the endocrine tumors studied indicates that autocrine/paracrine circuits may be active in neoplastic conditions... - Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and functionRiccarda Granata
Laboratory of Molecular and Cellular Endocrinology, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Corso Dogliotti, 14 10126 Turin, Italy
Diabetes 57:967-79. 2008..We investigated obestatin effect on survival of beta-cells and human pancreatic islets and the underlying signaling pathways... - Role of galectin-3 immunodetection in the cytological diagnosis of thyroid cystic papillary carcinomaMauro Papotti
Department of Pathology, University of Turin, Italy
Eur J Endocrinol 147:515-21. 2002..The aim of this study was to assess the role of galectin-3 immunodetection in a series of FNA cytological samples of benign and malignant thyroid cystic nodules... - Oxytocin is a growth factor for Kaposi's sarcoma cells: evidence of endocrine-immunological cross-talkPaola Cassoni
Department of Biomedical Sciences and Human Oncology, University of Turin, Via Santena 7, 10126 Turin, Italy
Cancer Res 62:2406-13. 2002.... - Excision repair cross complementing-1 and topoisomerase IIalpha gene expression in small-cell lung cancer patients treated with platinum and etoposide: a retrospective studyPaolo Ceppi
Thoracic Oncology Unit, University of Torino, S Luigi Hospital, Orbassano Torino, Italy
J Thorac Oncol 3:583-9. 2008..Aim of the study was to quantify ERCC1, RRM1, and TopoIIalpha mRNA expression profile as predictive factors for response and survival in SCLC patients treated with platinum/etoposide... - Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre studyArmando Bartolazzi
Department of Pathology, St Andrea University Hospital, Rome, Italy
Lancet Oncol 9:543-9. 2008..We aimed to assess the diagnostic effect of galectin-3 expression analysis in distinguishing preoperatively benign from malignant follicular thyroid nodules when FNA findings were indeterminate... - Diagnostic role of galectin-3 in follicular thyroid tumorsMarco Volante
Virchows Arch 444:309-12. 2004 - Merkel cell carcinomas: expression of S-phase kinase-associated protein 2 (Skp2), p27, and proliferation markersLori A Erickson
Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Endocr Pathol 14:221-29. 2003.... - RET activation and clinicopathologic features in poorly differentiated thyroid tumorsMassimo Santoro
Centro di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, Dipartimento di Biologia e Patologia Cellulare e Molecolare, , 80131 Naples, Italy
J Clin Endocrinol Metab 87:370-9. 2002.... - GSTT1 and M1 polymorphisms in Hürthle thyroid cancer patientsKarmen Stankov
Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, Unita Operativa di Genetica Medica, Policlinico S Orsola Malpighi, Pad 11, Via Massarenti 9, 40138 Bologna, Italy
Cancer Lett 240:76-82. 2006..6% in controls (OR 1.24; 95% CI, 0.62-2.48), indicating that the GSTT1 and M1 null genotypes do not increase the risk of development of oxyphilic tumors... - Galectin-3 expression in hyalinizing trabecular tumors of the thyroid glandRobyn L Gaffney
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Am J Surg Pathol 27:494-8. 2003..Our study suggests that the variable pattern of galectin-3 expression may reflect a difference in biologic behavior between HTT and papillary thyroid carcinoma... - Allelic loss on chromosomes 2q21 and 19p 13.2 in oxyphilic thyroid tumorsKarmen Stankov
Dipartimento di Medicina Interna, Cardioangiologia ed Epatologia, , Policlinico S. Orsola-Malpighi, Bologna, Italy
Int J Cancer 111:463-7. 2004..This led to the exclusion of linkage with the NMTC1 locus and to the refutation of the digenic inheritance hypothesis at least in this family...