Research Topics
| F VisioliSummaryAffiliation: University of Milan Country: Italy Publications
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Publications
Mediterranean food and health: building human evidenceF Visioli
Department of Pharmacological Sciences, University of Milan, Italy
J Physiol Pharmacol 56:37-49. 2005....- The role of antioxidants in the Mediterranean dietF Visioli
University of Milan, Department of Pharmacological Sciences, Italy
Lipids 36:S49-52. 2001.... - Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administrationFrancesco Visioli
Department of Pharmacological Sciences, University of Milan, 20133 Milan, Italy
J Nutr 133:2612-5. 2003..These data suggest that the rat is not the appropriate model for the study of HT metabolism and that HT-containing functional foods should be carefully formulated... - Biological properties of olive oil phytochemicalsFrancesco Visioli
University of Milan, Department of Pharmacological Sciences, Italy
Crit Rev Food Sci Nutr 42:209-21. 2002.... - Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione statusFrancesco Visioli
Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA
Redox Rep 7:223-7. 2002..Thus, vitamin C and lipoic acid potentiate endothelial NO synthesis and bioactivity by mechanisms that appear to be independent of cellular GSH levels and redox environment... - Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acidsFrancesco Visioli
University of Milan, Department of Pharmacological Sciences, 20133 Milan, Italy
Lipids 38:415-8. 2003.... - Protective activity of tomato products on in vivo markers of lipid oxidationFrancesco Visioli
Department of Pharmacological Science, University of Milan, Via Balzaretti 9, 20133, Milano, Italy
Eur J Nutr 42:201-6. 2003..It has been suggested that regular consumption of tomato products improves antioxidant defenses due to their endogenous antioxidant compounds, notably lycopene... - The roller coaster of antioxidant therapyFrancesco Visioli
University of Milan, Department of Pharmacological Sciences, Italy
Curr Med Chem 11:3 p. preceeding 1085. 2004 - Local food and cardioprotection: the role of phytochemicalsFrancesco Visioli
Department of Pharmacological Sciences, University of Milan, Milan, Italy
Forum Nutr 59:116-29. 2006..In synthesis, the data uniformly demonstrate that phytochemical components of the Mediterranean diet exert cardioprotective effects whose mechanisms are being progressively elucidated... - The role of antioxidants in the mediterranean diets: focus on cancerF Visioli
University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133 Milan, Italy
Eur J Cancer Prev 13:337-43. 2004.... - Lipid transport, dietary fats, and endogenous lipid synthesis: hypotheses on saturation and competition processesFrancesco Visioli
University of Milan, Department of Pharmacological Sciences, Italy
Nutr Health 18:127-32. 2006..In turn, a theory on the dietary vs endogenous contribution to circulating fatty acids, including those known as non-essential, is discussed based on critical interpretation of original data... - VasoCare. VasogenF Visioli
University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
Curr Opin Investig Drugs 2:1247-9. 2001..In June 2001, the USPTO issued a patent entitled 'Method for Preventing and Reversing Atherosclerosis', covering the use of VasoCare in the prevention and reduction of atherosclerosis [411783]... - Hydroxytyrosol, as a component of olive mill waste water, is dose- dependently absorbed and increases the antioxidant capacity of rat plasmaF Visioli
Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan
Free Radic Res 34:301-5. 2001..Future experiments will eventually further clarify its metabolic fate and its in vivo actions... - Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophagesF Visioli
Institute of Pharmacological Sciences, Milan, Italy
Life Sci 62:541-6. 1998..Taken together, our data suggest that, during endotoxin challenge, oleuropein potentiates the macrophage-mediated response, resulting in higher NO production, currently believed to be beneficial for cellular and organismal protection... - Oxidation of individual fatty acids yields different profiles of oxidation markersF Visioli
Institute of Pharmacological Sciences, University of Milan, Italy
Biochem Biophys Res Commun 245:487-9. 1998.... - Ethanol enhances cholesterol synthesis and secretion in human hepatomal cellsF Visioli
University of Milan, Institute of Pharmacological Sciences, Italy
Alcohol 15:299-303. 1998..The observed modifications of lipid metabolism in HepG2 may partially explain the enhanced incidence of cardiovascular disorders that has been associated with alcoholism... - The kinetics of copper-induced LDL oxidation depend upon its lipid composition and antioxidant contentF Visioli
Institute of Pharmacological Sciences, University of Milan, Milan, Italy
Biochem Biophys Res Commun 268:818-22. 2000..We suggest that copper undergoes redox transitions in LDL by utilizing reducing equivalents originating from endogenous antioxidants and/or from lipid peroxides in the LDL lipid core... - Olive oil phenolics are dose-dependently absorbed in humansF Visioli
Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Milan, Italy
FEBS Lett 468:159-60. 2000..Furthermore, an increase in the dose of phenolics administered increased the proportion of conjugation with glucuronide... - In vitro differentiation of human monocytes to macrophages results in depletion of antioxidants and increase in n-3 fatty acids levelsF Visioli
Institute of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
FEBS Lett 471:75-7. 2000.... - Diet and prevention of coronary heart disease: the potential role of phytochemicalsF Visioli
University of Milan, Institute of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
Cardiovasc Res 47:419-25. 2000..This article reviews the evidence that links a high dietary intake of phytochemicals from various sources with a reduced incidence of coronary heart disease... - Antiatherogenic components of olive oilF Visioli
Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, Milan 20133, Italy
Curr Atheroscler Rep 3:64-7. 2001.... - Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humansF Visioli
Institute of Pharmacological Sciences, Milan, Italy
Biochem Biophys Res Commun 278:797-9. 2000..The statistically significant negative correlation between 8-iso-PGF(2alpha) and HValc urinary concentrations suggests that this metabolite better reflects the in vivo activities of hydroxytyrosol... - Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stressF Visioli
University of Milan, Institute of Pharmacological Sciences, Milan, Italy
Circulation 102:2169-71. 2000..We tested the effects of a low dose of an OMWW extract in a model of sidestream smoke-induced oxidative stress in rats by evaluating the urinary excretion of 8-iso-prostaglandin (PG) F(2alpha) (iPF(2alpha)-III)... - Urinary excretion of olive oil phenols and their metabolites in humansD Caruso
Department of Pharmacological Sciences, University of Milan, Milan, Italy
Metabolism 50:1426-8. 2001..We also found a significant increase of HVA, indicating an oxidation of the ethanolic residue of HT and/or of HVA1c in humans. The excretion of both metabolites significantly correlated with the dose of administered HT... - Lycopene and vitamin C concentrations increase in plasma and lymphocytes after tomato intake. Effects on cellular antioxidant protectionP Riso
Department of Food Science and Technology, Division of Human Nutrition, University of Milan, Italy
Eur J Clin Nutr 58:1350-8. 2004..This study seeks to verify whether the regular consumption of small amounts of tomato products can protect lymphocyte DNA and lipids from oxidative damage... - Synthesis of long-chain polyunsaturated fatty acids is inhibited in vivo in hypercholesterolemic rabbits and in vitro by oxysterolsP Rise
Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
Prostaglandins Leukot Essent Fatty Acids 71:79-86. 2004..In conclusion, atherogenic oxysterols interfere with the production of long-chain polyunsaturated fatty acids from their precursors both in hypercholesterolemic rabbits and in cultured cells... - Antioxidant and other biological activities of olive mill waste watersF Visioli
Institute of Pharmacological Sciences, Milan, Italy
J Agric Food Chem 47:3397-401. 1999..The potency of the extracts depended on their degree of refinement: extracts containing only low molecular weight phenols were the most effective... - Antioxidant activity of wild plants collected in Valsesia, an alpine region of Northern ItalyS Vitalini
Department of Biology, University of Milan, Italy
Phytother Res 20:576-80. 2006..Given that a diet rich in wild plants is associated with a reduced incidence of degenerative diseases, such as atherosclerosis and cancer, this study suggests that some Valsesia plants could be pharmaceutically exploited... 
Lipoic acid significantly restores, in rats, the age-related decline in vasomotionA R Smith
Department of Biochemistry and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, OR, USA
Br J Pharmacol 153:1615-22. 2008..We hypothesized that ceramide accumulation was from an age-related loss of endothelial glutathione (GSH) and subsequent activation of neutral sphingomyelinase (nSMase), an enzyme whose activity increases when GSH is limited...- Lepidium meyenii (Maca) does not exert direct androgenic activitiesP Bogani
Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
J Ethnopharmacol 104:415-7. 2006..Further experiments are needed to assess which compound, of the several Maca's components, is responsible of the observed in vivo effects... - Ascorbic acid in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trialDavide Pareyson
Clinic of Central and Peripheral Degenerative Neuropathies Unit, Department of Clinical Neurosciences, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Foundation, Carlo Besta Neurological Institute, Milan, Italy
Lancet Neurol 10:320-8. 2011..However, in three 1-year trials, ascorbic acid had no benefit in human beings. We did a multicentre 2-year trial to test the efficacy and tolerability of ascorbic acid in patients with CMT1A... - Reliability of clinical outcome measures in Charcot-Marie-Tooth diseaseA Solari
Neuroepidemiology Unit, IRCCS Foundation, C Besta Neurological Institute, Via Celoria 11, 20133 Milan, Italy
Neuromuscul Disord 18:19-26. 2008..All outcome measures appear adequate for CMT assessment. Use of an immobilization device improves foot MVIC reliability, preventing biased findings in patients with greater strength... 
Polyunsaturated fatty acids as antioxidantsDoriane Richard
Laboratory of Micronutrients and Cardiovascular Disease, UMR7079, UPMC Univ 06, Paris, France
Pharmacol Res 57:451-5. 2008....- Thiol supplementation inhibits metalloproteinase activity independent of glutathione statusPaola Bogani
Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
Biochem Biophys Res Commun 363:651-5. 2007..Although all thiols, these compounds have different properties and different cellular uptakes and metabolic characteristics, and this could explain, at least in part, their differential effects on MMPs... - Protective effect of olive oil minor polar components against oxidative damage in rats treated with ferric-nitrilotriacetateMonica Deiana
Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
Food Chem Toxicol 45:2434-40. 2007..In summary, MPC administration protects organs against lipid peroxidation and conserves the endogenous alpha-tocopherol... - Hydroxytyrosol-rich olive mill wastewater extract protects brain cells in vitro and ex vivoSebastian Schaffer
Institute of Pharmacology ZAFES, Biocenter Niederursel, University of Frankfurt, 60438 Frankfurt am Main, Germany
J Agric Food Chem 55:5043-9. 2007..In synthesis, the ex vivo data provide the first evidence of neuroprotective effects of oral hydroxytyrosol intake. Keywords: Hydroxytyrosol; olive mill wastewater; dissociated brain cells; oxidative stress; brain; Mediterranean diet... - Identification of minor secondary metabolites from the latex of Croton lechleri (Muell-Arg) and evaluation of their antioxidant activitySimona De Marino
Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Ita
Molecules 13:1219-29. 2008..In vitro antioxidant activities were assessed by DPPH, total antioxidant capacity and lipid peroxidation assays. Flavan-3-ols derivatives (as major phenolic compounds in the latex) exhibited the highest antioxidant activity... - Antioxidants in the Mediterranean diets: An updatePaola Bogani
Institute of Pharmacological Sciences, University of Milan, Milan, Italy
World Rev Nutr Diet 97:162-79. 2007 - Mediterranean diet as a nutrition education and dietary guide: misconceptions and the neglected role of locally consumed foods and wild green plantsYannis Manios
Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
Forum Nutr 59:154-70. 2006.... - Flavonoid characterization and in vitro antioxidant activity of Aconitum anthora L. (Ranunculaceae)Cristina Mariani
Dipartimento di Biologia, Universita di Milano, Via Celoria 26, 20133 Milano, Italy
Phytochemistry 69:1220-6. 2008..anthora. The antioxidant activity of the four identified flavonoids was screened by three in vitro tests... - Phenolic glycosides from Foeniculum vulgare fruit and evaluation of antioxidative activitySimona De Marino
Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli Federico II, via D Montesano 49, I 80131 Naples, Italy
Phytochemistry 68:1805-12. 2007..Their structures were elucidated by spectral methods including 1D, 2D NMR and MS and chemical methods. Antioxidant activity was tested using three methods: DPPH(), total antioxidant capacity and assay of lipid peroxidation... - A multicenter, randomized, double-blind, placebo-controlled trial of long-term ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL): the study protocol [EudraCT no.: 2006-000032-27]Davide Pareyson
Department of Biochemistry and Genetics, C Besta National Neurological Institute, Via Celoria 11, 20133 Milan, Italy
Pharmacol Res 54:436-41. 2006..In consenting patients from three centers, skin biopsy is performed to evaluate PMP22 expression. The study will last 34 months, starting from March 2006... - Nutritional strategies for healthy cardiovascular aging: focus on micronutrientsFrancesco Visioli
UMR 7079, Universite Paris 6 Pierre et Marie Curie, 7 quai Saint Bernard, Batiment A, 5eme etage, 75005 Paris, France
Pharmacol Res 55:199-206. 2007..In this article we review the known effects of micronutrients on the aging heart and we propose strategies for dietary improvements... - Evolution of minor polar compounds and antioxidant capacity during storage of bottled extra virgin olive oilAnnalisa Romani
Department of Pharmaceutical Science, University of Florence, Sesto Fiorentino, Florence, Italy
J Agric Food Chem 55:1315-20. 2007..The tests on the stable free radical DPPH* confirmed the results on human LDL. We propose this as an additional parameter to evaluate olive oil quality and stability over time... - Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal womenSimonetta Salvini
Molecular and Nutritional Epidemiology Unit, Centro per lo Studio e la Prevenzione Oncologica CSPO, Scientific Institute of Tuscany, Florence, Italy
Br J Nutr 95:742-51. 2006..Despite the small sample size, the present study showed a reduction of DNA damage by consumption of an EVOO rich in phenols, particularly hydroxytyrosol... - Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stressPatrizia Riso
Department of Food Science and Microbiology, Division of Human Nutrition, University of Milan, Milan 20133, Italy
J Agric Food Chem 54:2563-6. 2006..Future intervention trials in subjects with low carotenoid status and/or compromised immune system will resolve the issue of whether carotenoids modulate immune parameters in humans... - Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oilPaola Bogani
Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
Atherosclerosis 190:181-6. 2007..These data reinforce the notion that the Mediterranean diet reduces the incidence of coronary heart disease partially due to the protective role of its phenolic components, including those of extra virgin olive oil... - Antioxidant and other biological activities of phenols from olives and olive oilFrancesco Visioli
Department of Pharmacological Sciences, University of Milan, Milan, Italy
Med Res Rev 22:65-75. 2002.... - Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acidTory M Hagen
Department of Biochemistry and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
Ann N Y Acad Sci 959:491-507. 2002..Thus, ALCAR along with lipoic acid may be effective supplemental regimens to maintain myocardial function... - Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acidAnthony R Smith
Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
FASEB J 16:1102-4. 2002..Vitamin C supplementation should be considered when using cultured cells, especially when experimental endpoints are related to cellular redox status and eNOS activity... - Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicalsMaria Annunziata Carluccio
C.N.R. Institute of Clinical Physiology, Lecce, Italy
Arterioscler Thromb Vasc Biol 23:622-9. 2003..CONCLUSIONS: Olive oil and red wine antioxidant polyphenols at nutritionally relevant concentrations transcriptionally inhibit endothelial adhesion molecule expression, thus partially explaining atheroprotection from Mediterranean diets... - Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritantsEmmanuela Corsini
Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Italy
J Invest Dermatol 121:337-44. 2003..ADRP expression was also induced in vivo following treatment with sodium dodecyl sulfate in an experimental model of skin irritation, indicating that the in vitro model represents irritation... - Folic acid and vitamin E supplementation effects on homocysteinemia, endothelial function and plasma antioxidant capacity in young myocardial-infarction patientsDeodato Assanelli
Institute of Internal Medicine, University of Brescia, Brescia, Italy
Pharmacol Res 49:79-84. 2004..Confirming previous reports, the effects of Vitamin E are still equivocal... - Vasomodulating potential of mediterranean wild plant extractsSimona Grande
Department of Pharmacological Sciences, University of Milan, Milan, Italy
J Agric Food Chem 52:5021-6. 2004.... - Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patientsFrancesco Visioli
Dept. of Pharmacological Sciences, University of Milan, Milan, Italy
Eur J Nutr 44:121-7. 2005..CONCLUSIONS: EVOO consumption by mildly dyslipidemic patients is associated with favorable changes in circulating markers of cardiovascular condition. Based on current knowledge, these effects may be associated with cardioprotection... - n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive ratsLaura Raimondi
Dept of Pharmacology, University of Florence, Florence, Italy
Eur J Nutr 44:327-33. 2005..We hypothesised that ADMA reduction might be a part of EPA and DHA beneficial effects on the cardiovascular system... - Wild artichoke prevents the age-associated loss of vasomotor functionGiuseppe Rossoni
Department of Pharmacological Sciences, University of Milan, Milan 20133, Italy
J Agric Food Chem 53:10291-6. 2005.... - Daily intake of a formulated tomato drink affects carotenoid plasma and lymphocyte concentrations and improves cellular antioxidant protectionMarisa Porrini
Department of Food Science and Technology, Division of Human Nutrition, University of Milan, Milan, Italy
Br J Nutr 93:93-9. 2005..0001) in lymphocytes subjected to oxidative stress. In conclusion, the present study supports the fact that a low intake of carotenoids from tomato products improves cell antioxidant protection... - Effects of blood orange juice intake on antioxidant bioavailability and on different markers related to oxidative stressPatrizia Riso
Department of Food Science and Technology and Microbiology, Division of Human Nutrition, University of Milan, 21033 Milan, Italy
J Agric Food Chem 53:941-7. 2005.... - Hypochlorous acid scavenging properties of local Mediterranean plant foodsSebastian Schaffer
Institute of Pharmacology (ZAFES, Biocenter Niederursel, University of Frankfurt, Frankfurt am Main, Germany
Lipids 39:1239-47. 2004..pulegioides. In synthesis, our study shows that local Mediterranean plant foods prevent HOCl toxicity in vitro and, thus, suggests further mechanisms responsible for the reported health-beneficial effect of the Mediterranean diet... - The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformationGiulia Corona
Molecular Nutrition Group, School of Food Biosciences, University of Reading, UK
Free Radic Res 40:647-58. 2006..Our study provides additional information regarding the breakdown of complex olive oil polyphenols in the GI tract, in particular the stomach and the large intestine... - Alpha-linolenic acid and cardiovascular diseaseFrancesco Visioli
Am J Clin Nutr 75:1121; author reply 1121-2. 2002 - Limitations in study of sugar-sweetened beveragesFrancesco Visioli
J Am Diet Assoc 108:34-5; author reply 35. 2008 - Assessment of nutritional profiles: a novel system based on a comprehensive approachFrancesco Visioli
Laboratory of Micronutrients and Cardiovascular Disease, UMR7079, Universite Pierre et Marie Curie Paris 6, Bat A, 5 étage, 7 quai Saint Bernard, 75005 Paris, France
Br J Nutr 98:1101-7. 2007..Moreover, this approach allows for rapid modification and great flexibility to suit individual needs and gastronomic habits... - The water-soluble vitamin E analogue Trolox protects against ischaemia/reperfusion damage in vitro and ex vivo. A comparison with vitamin EVadim F Sagach
A. A. Bogomolets Institute of Physiology, Kiev, Ukraine
Pharmacol Res 45:435-9. 2002..These differential effects are likely due to the scavenging, by Trolox, of reactive oxygen species generated in the water phase... - Quenching of intracellular ROS generation as a mechanism for oleate-induced reduction of endothelial activation and early atherogenesisMarika Massaro
Laboratory for Thrombosis and Vascular Research, C.N.R. Institute of Clinical Physiology, Pisa, Italy
Thromb Haemost 88:335-44. 2002..These results indicate that oleate may exert direct vascular atheroprotective effects by inhibiting endothelial activation through a quenching of stimuli-induced increase in ROS... - Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leavesMaria Camilla Baratto
Dipartimento di Chimica, , Via Aldo Moro, 1-53100 Siena, Italy
Free Radic Res 37:405-12. 2003..All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical... - Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2AAnthony R Smith
Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
Aging Cell 5:391-400. 2006..Taken together, these results suggest a novel mechanism that at least partly explains the persistent loss of eNOS activity and endothelial-derived NO availability in aging conduit arteries... - Determinants of early-onset cardiovascular disease: a case-control study of young myocardial infarction patientsDeodato Assanelli
University of Brescia, Brescia, Italy
Ital Heart J 5:604-11. 2004.... - Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with ageAnthony R Smith
Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
Arch Biochem Biophys 454:100-5. 2006..These results suggest that age-dependent loss of NO may be partly caused by differences in eNOS subcellular distribution and its association with inhibitory proteins...