F Visioli

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi request reprint Mediterranean food and health: building human evidence
    F Visioli
    Department of Pharmacological Sciences, University of Milan, Italy
    J Physiol Pharmacol 56:37-49. 2005
  2. ncbi request reprint The role of antioxidants in the Mediterranean diet
    F Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Lipids 36:S49-52. 2001
  3. ncbi request reprint Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration
    Francesco Visioli
    Department of Pharmacological Sciences, University of Milan, 20133 Milan, Italy
    J Nutr 133:2612-5. 2003
  4. ncbi request reprint Biological properties of olive oil phytochemicals
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Crit Rev Food Sci Nutr 42:209-21. 2002
  5. ncbi request reprint Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status
    Francesco Visioli
    Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA
    Redox Rep 7:223-7. 2002
  6. ncbi request reprint Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acids
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, 20133 Milan, Italy
    Lipids 38:415-8. 2003
  7. ncbi request reprint Protective activity of tomato products on in vivo markers of lipid oxidation
    Francesco Visioli
    Department of Pharmacological Science, University of Milan, Via Balzaretti 9, 20133, Milano, Italy
    Eur J Nutr 42:201-6. 2003
  8. ncbi request reprint The roller coaster of antioxidant therapy
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Curr Med Chem 11:3 p. preceeding 1085. 2004
  9. ncbi request reprint Local food and cardioprotection: the role of phytochemicals
    Francesco Visioli
    Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Forum Nutr 59:116-29. 2006
  10. ncbi request reprint The role of antioxidants in the mediterranean diets: focus on cancer
    F Visioli
    University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Cancer Prev 13:337-43. 2004

Detail Information

Publications70

  1. ncbi request reprint Mediterranean food and health: building human evidence
    F Visioli
    Department of Pharmacological Sciences, University of Milan, Italy
    J Physiol Pharmacol 56:37-49. 2005
    ....
  2. ncbi request reprint The role of antioxidants in the Mediterranean diet
    F Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Lipids 36:S49-52. 2001
    ....
  3. ncbi request reprint Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration
    Francesco Visioli
    Department of Pharmacological Sciences, University of Milan, 20133 Milan, Italy
    J Nutr 133:2612-5. 2003
    ..These data suggest that the rat is not the appropriate model for the study of HT metabolism and that HT-containing functional foods should be carefully formulated...
  4. ncbi request reprint Biological properties of olive oil phytochemicals
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Crit Rev Food Sci Nutr 42:209-21. 2002
    ....
  5. ncbi request reprint Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status
    Francesco Visioli
    Linus Pauling Institute, Oregon State University, Corvallis, Oregon, USA
    Redox Rep 7:223-7. 2002
    ..Thus, vitamin C and lipoic acid potentiate endothelial NO synthesis and bioactivity by mechanisms that appear to be independent of cellular GSH levels and redox environment...
  6. ncbi request reprint Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acids
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, 20133 Milan, Italy
    Lipids 38:415-8. 2003
    ....
  7. ncbi request reprint Protective activity of tomato products on in vivo markers of lipid oxidation
    Francesco Visioli
    Department of Pharmacological Science, University of Milan, Via Balzaretti 9, 20133, Milano, Italy
    Eur J Nutr 42:201-6. 2003
    ..It has been suggested that regular consumption of tomato products improves antioxidant defenses due to their endogenous antioxidant compounds, notably lycopene...
  8. ncbi request reprint The roller coaster of antioxidant therapy
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Curr Med Chem 11:3 p. preceeding 1085. 2004
  9. ncbi request reprint Local food and cardioprotection: the role of phytochemicals
    Francesco Visioli
    Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Forum Nutr 59:116-29. 2006
    ..In synthesis, the data uniformly demonstrate that phytochemical components of the Mediterranean diet exert cardioprotective effects whose mechanisms are being progressively elucidated...
  10. ncbi request reprint The role of antioxidants in the mediterranean diets: focus on cancer
    F Visioli
    University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133 Milan, Italy
    Eur J Cancer Prev 13:337-43. 2004
    ....
  11. ncbi request reprint Lipid transport, dietary fats, and endogenous lipid synthesis: hypotheses on saturation and competition processes
    Francesco Visioli
    University of Milan, Department of Pharmacological Sciences, Italy
    Nutr Health 18:127-32. 2006
    ..In turn, a theory on the dietary vs endogenous contribution to circulating fatty acids, including those known as non-essential, is discussed based on critical interpretation of original data...
  12. ncbi request reprint VasoCare. Vasogen
    F Visioli
    University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
    Curr Opin Investig Drugs 2:1247-9. 2001
    ..In June 2001, the USPTO issued a patent entitled 'Method for Preventing and Reversing Atherosclerosis', covering the use of VasoCare in the prevention and reduction of atherosclerosis [411783]...
  13. ncbi request reprint Hydroxytyrosol, as a component of olive mill waste water, is dose- dependently absorbed and increases the antioxidant capacity of rat plasma
    F Visioli
    Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan
    Free Radic Res 34:301-5. 2001
    ..Future experiments will eventually further clarify its metabolic fate and its in vivo actions...
  14. ncbi request reprint Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages
    F Visioli
    Institute of Pharmacological Sciences, Milan, Italy
    Life Sci 62:541-6. 1998
    ..Taken together, our data suggest that, during endotoxin challenge, oleuropein potentiates the macrophage-mediated response, resulting in higher NO production, currently believed to be beneficial for cellular and organismal protection...
  15. ncbi request reprint Oxidation of individual fatty acids yields different profiles of oxidation markers
    F Visioli
    Institute of Pharmacological Sciences, University of Milan, Italy
    Biochem Biophys Res Commun 245:487-9. 1998
    ....
  16. ncbi request reprint Ethanol enhances cholesterol synthesis and secretion in human hepatomal cells
    F Visioli
    University of Milan, Institute of Pharmacological Sciences, Italy
    Alcohol 15:299-303. 1998
    ..The observed modifications of lipid metabolism in HepG2 may partially explain the enhanced incidence of cardiovascular disorders that has been associated with alcoholism...
  17. ncbi request reprint The kinetics of copper-induced LDL oxidation depend upon its lipid composition and antioxidant content
    F Visioli
    Institute of Pharmacological Sciences, University of Milan, Milan, Italy
    Biochem Biophys Res Commun 268:818-22. 2000
    ..We suggest that copper undergoes redox transitions in LDL by utilizing reducing equivalents originating from endogenous antioxidants and/or from lipid peroxides in the LDL lipid core...
  18. ncbi request reprint Olive oil phenolics are dose-dependently absorbed in humans
    F Visioli
    Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Milan, Italy
    FEBS Lett 468:159-60. 2000
    ..Furthermore, an increase in the dose of phenolics administered increased the proportion of conjugation with glucuronide...
  19. ncbi request reprint In vitro differentiation of human monocytes to macrophages results in depletion of antioxidants and increase in n-3 fatty acids levels
    F Visioli
    Institute of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
    FEBS Lett 471:75-7. 2000
    ....
  20. ncbi request reprint Diet and prevention of coronary heart disease: the potential role of phytochemicals
    F Visioli
    University of Milan, Institute of Pharmacological Sciences, Via Balzaretti 9, 20133, Milan, Italy
    Cardiovasc Res 47:419-25. 2000
    ..This article reviews the evidence that links a high dietary intake of phytochemicals from various sources with a reduced incidence of coronary heart disease...
  21. ncbi request reprint Antiatherogenic components of olive oil
    F Visioli
    Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, Milan 20133, Italy
    Curr Atheroscler Rep 3:64-7. 2001
    ....
  22. ncbi request reprint Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans
    F Visioli
    Institute of Pharmacological Sciences, Milan, Italy
    Biochem Biophys Res Commun 278:797-9. 2000
    ..The statistically significant negative correlation between 8-iso-PGF(2alpha) and HValc urinary concentrations suggests that this metabolite better reflects the in vivo activities of hydroxytyrosol...
  23. ncbi request reprint Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stress
    F Visioli
    University of Milan, Institute of Pharmacological Sciences, Milan, Italy
    Circulation 102:2169-71. 2000
    ..We tested the effects of a low dose of an OMWW extract in a model of sidestream smoke-induced oxidative stress in rats by evaluating the urinary excretion of 8-iso-prostaglandin (PG) F(2alpha) (iPF(2alpha)-III)...
  24. ncbi request reprint Urinary excretion of olive oil phenols and their metabolites in humans
    D Caruso
    Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Metabolism 50:1426-8. 2001
    ..We also found a significant increase of HVA, indicating an oxidation of the ethanolic residue of HT and/or of HVA1c in humans. The excretion of both metabolites significantly correlated with the dose of administered HT...
  25. ncbi request reprint Lycopene and vitamin C concentrations increase in plasma and lymphocytes after tomato intake. Effects on cellular antioxidant protection
    P Riso
    Department of Food Science and Technology, Division of Human Nutrition, University of Milan, Italy
    Eur J Clin Nutr 58:1350-8. 2004
    ..This study seeks to verify whether the regular consumption of small amounts of tomato products can protect lymphocyte DNA and lipids from oxidative damage...
  26. ncbi request reprint Synthesis of long-chain polyunsaturated fatty acids is inhibited in vivo in hypercholesterolemic rabbits and in vitro by oxysterols
    P Rise
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Prostaglandins Leukot Essent Fatty Acids 71:79-86. 2004
    ..In conclusion, atherogenic oxysterols interfere with the production of long-chain polyunsaturated fatty acids from their precursors both in hypercholesterolemic rabbits and in cultured cells...
  27. ncbi request reprint Antioxidant and other biological activities of olive mill waste waters
    F Visioli
    Institute of Pharmacological Sciences, Milan, Italy
    J Agric Food Chem 47:3397-401. 1999
    ..The potency of the extracts depended on their degree of refinement: extracts containing only low molecular weight phenols were the most effective...
  28. ncbi request reprint Antioxidant activity of wild plants collected in Valsesia, an alpine region of Northern Italy
    S Vitalini
    Department of Biology, University of Milan, Italy
    Phytother Res 20:576-80. 2006
    ..Given that a diet rich in wild plants is associated with a reduced incidence of degenerative diseases, such as atherosclerosis and cancer, this study suggests that some Valsesia plants could be pharmaceutically exploited...
  29. pmc Lipoic acid significantly restores, in rats, the age-related decline in vasomotion
    A R Smith
    Department of Biochemistry and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, OR, USA
    Br J Pharmacol 153:1615-22. 2008
    ..We hypothesized that ceramide accumulation was from an age-related loss of endothelial glutathione (GSH) and subsequent activation of neutral sphingomyelinase (nSMase), an enzyme whose activity increases when GSH is limited...
  30. ncbi request reprint Lepidium meyenii (Maca) does not exert direct androgenic activities
    P Bogani
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    J Ethnopharmacol 104:415-7. 2006
    ..Further experiments are needed to assess which compound, of the several Maca's components, is responsible of the observed in vivo effects...
  31. pmc Ascorbic acid in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trial
    Davide Pareyson
    Clinic of Central and Peripheral Degenerative Neuropathies Unit, Department of Clinical Neurosciences, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Foundation, Carlo Besta Neurological Institute, Milan, Italy
    Lancet Neurol 10:320-8. 2011
    ..However, in three 1-year trials, ascorbic acid had no benefit in human beings. We did a multicentre 2-year trial to test the efficacy and tolerability of ascorbic acid in patients with CMT1A...
  32. ncbi request reprint Reliability of clinical outcome measures in Charcot-Marie-Tooth disease
    A Solari
    Neuroepidemiology Unit, IRCCS Foundation, C Besta Neurological Institute, Via Celoria 11, 20133 Milan, Italy
    Neuromuscul Disord 18:19-26. 2008
    ..All outcome measures appear adequate for CMT assessment. Use of an immobilization device improves foot MVIC reliability, preventing biased findings in patients with greater strength...
  33. doi request reprint Polyunsaturated fatty acids as antioxidants
    Doriane Richard
    Laboratory of Micronutrients and Cardiovascular Disease, UMR7079, UPMC Univ 06, Paris, France
    Pharmacol Res 57:451-5. 2008
    ....
  34. ncbi request reprint Thiol supplementation inhibits metalloproteinase activity independent of glutathione status
    Paola Bogani
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Biochem Biophys Res Commun 363:651-5. 2007
    ..Although all thiols, these compounds have different properties and different cellular uptakes and metabolic characteristics, and this could explain, at least in part, their differential effects on MMPs...
  35. ncbi request reprint Protective effect of olive oil minor polar components against oxidative damage in rats treated with ferric-nitrilotriacetate
    Monica Deiana
    Dipartimento di Biologia Sperimentale, Sezione di Patologia Sperimentale, Universita degli Studi di Cagliari, Cittadella Universitaria SS 554, 09042 Monserrato, Cagliari, Italy
    Food Chem Toxicol 45:2434-40. 2007
    ..In summary, MPC administration protects organs against lipid peroxidation and conserves the endogenous alpha-tocopherol...
  36. ncbi request reprint Hydroxytyrosol-rich olive mill wastewater extract protects brain cells in vitro and ex vivo
    Sebastian Schaffer
    Institute of Pharmacology ZAFES, Biocenter Niederursel, University of Frankfurt, 60438 Frankfurt am Main, Germany
    J Agric Food Chem 55:5043-9. 2007
    ..In synthesis, the ex vivo data provide the first evidence of neuroprotective effects of oral hydroxytyrosol intake. Keywords: Hydroxytyrosol; olive mill wastewater; dissociated brain cells; oxidative stress; brain; Mediterranean diet...
  37. ncbi request reprint Identification of minor secondary metabolites from the latex of Croton lechleri (Muell-Arg) and evaluation of their antioxidant activity
    Simona De Marino
    Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli Federico II, via D Montesano 49, I 80131 Napoli, Ita
    Molecules 13:1219-29. 2008
    ..In vitro antioxidant activities were assessed by DPPH, total antioxidant capacity and lipid peroxidation assays. Flavan-3-ols derivatives (as major phenolic compounds in the latex) exhibited the highest antioxidant activity...
  38. ncbi request reprint Antioxidants in the Mediterranean diets: An update
    Paola Bogani
    Institute of Pharmacological Sciences, University of Milan, Milan, Italy
    World Rev Nutr Diet 97:162-79. 2007
  39. ncbi request reprint Mediterranean diet as a nutrition education and dietary guide: misconceptions and the neglected role of locally consumed foods and wild green plants
    Yannis Manios
    Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Forum Nutr 59:154-70. 2006
    ....
  40. doi request reprint Flavonoid characterization and in vitro antioxidant activity of Aconitum anthora L. (Ranunculaceae)
    Cristina Mariani
    Dipartimento di Biologia, Universita di Milano, Via Celoria 26, 20133 Milano, Italy
    Phytochemistry 69:1220-6. 2008
    ..anthora. The antioxidant activity of the four identified flavonoids was screened by three in vitro tests...
  41. ncbi request reprint Phenolic glycosides from Foeniculum vulgare fruit and evaluation of antioxidative activity
    Simona De Marino
    Dipartimento di Chimica delle Sostanze Naturali, Universita degli Studi di Napoli Federico II, via D Montesano 49, I 80131 Naples, Italy
    Phytochemistry 68:1805-12. 2007
    ..Their structures were elucidated by spectral methods including 1D, 2D NMR and MS and chemical methods. Antioxidant activity was tested using three methods: DPPH(), total antioxidant capacity and assay of lipid peroxidation...
  42. ncbi request reprint A multicenter, randomized, double-blind, placebo-controlled trial of long-term ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL): the study protocol [EudraCT no.: 2006-000032-27]
    Davide Pareyson
    Department of Biochemistry and Genetics, C Besta National Neurological Institute, Via Celoria 11, 20133 Milan, Italy
    Pharmacol Res 54:436-41. 2006
    ..In consenting patients from three centers, skin biopsy is performed to evaluate PMP22 expression. The study will last 34 months, starting from March 2006...
  43. ncbi request reprint Nutritional strategies for healthy cardiovascular aging: focus on micronutrients
    Francesco Visioli
    UMR 7079, Universite Paris 6 Pierre et Marie Curie, 7 quai Saint Bernard, Batiment A, 5eme etage, 75005 Paris, France
    Pharmacol Res 55:199-206. 2007
    ..In this article we review the known effects of micronutrients on the aging heart and we propose strategies for dietary improvements...
  44. ncbi request reprint Evolution of minor polar compounds and antioxidant capacity during storage of bottled extra virgin olive oil
    Annalisa Romani
    Department of Pharmaceutical Science, University of Florence, Sesto Fiorentino, Florence, Italy
    J Agric Food Chem 55:1315-20. 2007
    ..The tests on the stable free radical DPPH* confirmed the results on human LDL. We propose this as an additional parameter to evaluate olive oil quality and stability over time...
  45. ncbi request reprint Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women
    Simonetta Salvini
    Molecular and Nutritional Epidemiology Unit, Centro per lo Studio e la Prevenzione Oncologica CSPO, Scientific Institute of Tuscany, Florence, Italy
    Br J Nutr 95:742-51. 2006
    ..Despite the small sample size, the present study showed a reduction of DNA damage by consumption of an EVOO rich in phenols, particularly hydroxytyrosol...
  46. ncbi request reprint Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stress
    Patrizia Riso
    Department of Food Science and Microbiology, Division of Human Nutrition, University of Milan, Milan 20133, Italy
    J Agric Food Chem 54:2563-6. 2006
    ..Future intervention trials in subjects with low carotenoid status and/or compromised immune system will resolve the issue of whether carotenoids modulate immune parameters in humans...
  47. ncbi request reprint Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil
    Paola Bogani
    Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    Atherosclerosis 190:181-6. 2007
    ..These data reinforce the notion that the Mediterranean diet reduces the incidence of coronary heart disease partially due to the protective role of its phenolic components, including those of extra virgin olive oil...
  48. ncbi request reprint Antioxidant and other biological activities of phenols from olives and olive oil
    Francesco Visioli
    Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Med Res Rev 22:65-75. 2002
    ....
  49. ncbi request reprint Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid
    Tory M Hagen
    Department of Biochemistry and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, Oregon 97331, USA
    Ann N Y Acad Sci 959:491-507. 2002
    ..Thus, ALCAR along with lipoic acid may be effective supplemental regimens to maintain myocardial function...
  50. ncbi request reprint Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid
    Anthony R Smith
    Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
    FASEB J 16:1102-4. 2002
    ..Vitamin C supplementation should be considered when using cultured cells, especially when experimental endpoints are related to cellular redox status and eNOS activity...
  51. ncbi request reprint Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals
    Maria Annunziata Carluccio
    C N R Institute of Clinical Physiology, Lecce, Italy
    Arterioscler Thromb Vasc Biol 23:622-9. 2003
    ..Because monocyte adhesion to the endothelium is crucial in early atherogenesis, we evaluated whether typical olive oil and red wine polyphenols affect endothelial-leukocyte adhesion molecule expression and monocyte adhesion...
  52. ncbi request reprint Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritants
    Emmanuela Corsini
    Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Italy
    J Invest Dermatol 121:337-44. 2003
    ..ADRP expression was also induced in vivo following treatment with sodium dodecyl sulfate in an experimental model of skin irritation, indicating that the in vitro model represents irritation...
  53. ncbi request reprint Folic acid and vitamin E supplementation effects on homocysteinemia, endothelial function and plasma antioxidant capacity in young myocardial-infarction patients
    Deodato Assanelli
    Institute of Internal Medicine, University of Brescia, Brescia, Italy
    Pharmacol Res 49:79-84. 2004
    ..Confirming previous reports, the effects of Vitamin E are still equivocal...
  54. ncbi request reprint Vasomodulating potential of mediterranean wild plant extracts
    Simona Grande
    Department of Pharmacological Sciences, University of Milan, Milan, Italy
    J Agric Food Chem 52:5021-6. 2004
    ....
  55. ncbi request reprint Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients
    Francesco Visioli
    Dept of Pharmacological Sciences, University of Milan, Milan, Italy
    Eur J Nutr 44:121-7. 2005
    ..In vitro, olive phenols exert potent antioxidant and enzyme-modulating activities...
  56. ncbi request reprint n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats
    Laura Raimondi
    Dept of Pharmacology, University of Florence, Florence, Italy
    Eur J Nutr 44:327-33. 2005
    ..We hypothesised that ADMA reduction might be a part of EPA and DHA beneficial effects on the cardiovascular system...
  57. ncbi request reprint Wild artichoke prevents the age-associated loss of vasomotor function
    Giuseppe Rossoni
    Department of Pharmacological Sciences, University of Milan, Milan 20133, Italy
    J Agric Food Chem 53:10291-6. 2005
    ....
  58. ncbi request reprint Daily intake of a formulated tomato drink affects carotenoid plasma and lymphocyte concentrations and improves cellular antioxidant protection
    Marisa Porrini
    Department of Food Science and Technology, Division of Human Nutrition, University of Milan, Milan, Italy
    Br J Nutr 93:93-9. 2005
    ..0001) in lymphocytes subjected to oxidative stress. In conclusion, the present study supports the fact that a low intake of carotenoids from tomato products improves cell antioxidant protection...
  59. ncbi request reprint Effects of blood orange juice intake on antioxidant bioavailability and on different markers related to oxidative stress
    Patrizia Riso
    Department of Food Science and Technology and Microbiology, Division of Human Nutrition, University of Milan, 21033 Milan, Italy
    J Agric Food Chem 53:941-7. 2005
    ....
  60. ncbi request reprint Hypochlorous acid scavenging properties of local Mediterranean plant foods
    Sebastian Schaffer
    Institute of Pharmacology ZAFES, Biocenter Niederursel, University of Frankfurt, Frankfurt am Main, Germany
    Lipids 39:1239-47. 2004
    ..pulegioides. In synthesis, our study shows that local Mediterranean plant foods prevent HOCl toxicity in vitro and, thus, suggests further mechanisms responsible for the reported health-beneficial effect of the Mediterranean diet...
  61. ncbi request reprint The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation
    Giulia Corona
    Molecular Nutrition Group, School of Food Biosciences, University of Reading, UK
    Free Radic Res 40:647-58. 2006
    ..Our study provides additional information regarding the breakdown of complex olive oil polyphenols in the GI tract, in particular the stomach and the large intestine...
  62. ncbi request reprint Alpha-linolenic acid and cardiovascular disease
    Francesco Visioli
    Am J Clin Nutr 75:1121; author reply 1121-2. 2002
  63. ncbi request reprint Limitations in study of sugar-sweetened beverages
    Francesco Visioli
    J Am Diet Assoc 108:34-5; author reply 35. 2008
  64. ncbi request reprint Assessment of nutritional profiles: a novel system based on a comprehensive approach
    Francesco Visioli
    Laboratory of Micronutrients and Cardiovascular Disease, UMR7079, Universite Pierre et Marie Curie Paris 6, Bat A, 5 ├ętage, 7 quai Saint Bernard, 75005 Paris, France
    Br J Nutr 98:1101-7. 2007
    ..Moreover, this approach allows for rapid modification and great flexibility to suit individual needs and gastronomic habits...
  65. ncbi request reprint The water-soluble vitamin E analogue Trolox protects against ischaemia/reperfusion damage in vitro and ex vivo. A comparison with vitamin E
    Vadim F Sagach
    A A Bogomolets Institute of Physiology, Kiev, Ukraine
    Pharmacol Res 45:435-9. 2002
    ..These differential effects are likely due to the scavenging, by Trolox, of reactive oxygen species generated in the water phase...
  66. ncbi request reprint Quenching of intracellular ROS generation as a mechanism for oleate-induced reduction of endothelial activation and early atherogenesis
    Marika Massaro
    Laboratory for Thrombosis and Vascular Research, C N R Institute of Clinical Physiology, Pisa, Italy
    Thromb Haemost 88:335-44. 2002
    ..These results indicate that oleate may exert direct vascular atheroprotective effects by inhibiting endothelial activation through a quenching of stimuli-induced increase in ROS...
  67. ncbi request reprint Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves
    Maria Camilla Baratto
    Dipartimento di Chimica, Universita degli Studi di Siena, Via Aldo Moro, 1 53100 Siena, Italy
    Free Radic Res 37:405-12. 2003
    ..All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical...
  68. ncbi request reprint Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A
    Anthony R Smith
    Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    Aging Cell 5:391-400. 2006
    ..Taken together, these results suggest a novel mechanism that at least partly explains the persistent loss of eNOS activity and endothelial-derived NO availability in aging conduit arteries...
  69. ncbi request reprint Determinants of early-onset cardiovascular disease: a case-control study of young myocardial infarction patients
    Deodato Assanelli
    University of Brescia, Brescia, Italy
    Ital Heart J 5:604-11. 2004
    ....
  70. ncbi request reprint Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age
    Anthony R Smith
    Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA
    Arch Biochem Biophys 454:100-5. 2006
    ..These results suggest that age-dependent loss of NO may be partly caused by differences in eNOS subcellular distribution and its association with inhibitory proteins...