D Virgintino

Summary

Affiliation: University of Bari
Country: Italy

Publications

  1. ncbi request reprint An intimate interplay between precocious, migrating pericytes and endothelial cells governs human fetal brain angiogenesis
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, 11, Bari 70124, Italy
    Angiogenesis 10:35-45. 2007
  2. ncbi request reprint Involvement of metalloprotease-2 in the development of human brain microvessels
    Francesco Girolamo
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Italy
    Histochem Cell Biol 122:261-70. 2004
  3. pmc Plasma membrane-derived microvesicles released from tip endothelial cells during vascular sprouting
    Daniela Virgintino
    Human Anatomy and Histology Unit, Department of Basic Medical Sciences, University of Bari School of Medicine, Piazza Giulio Cesare, Policlinico, 70124, Bari, Italy
    Angiogenesis 15:761-9. 2012
  4. ncbi request reprint Immunolocalization of tight junction proteins in the adult and developing human brain
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Bari, Italy
    Histochem Cell Biol 122:51-9. 2004
  5. ncbi request reprint Fetal blood-brain barrier P-glycoprotein contributes to brain protection during human development
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy
    J Neuropathol Exp Neurol 67:50-61. 2008
  6. ncbi request reprint VEGF expression is developmentally regulated during human brain angiogenesis
    Daniela Virgintino
    Dipartimento di Anatomia Umana e di Istologia, Universita di Bari, Italy
    Histochem Cell Biol 119:227-32. 2003
  7. ncbi request reprint Expression of P-glycoprotein in human cerebral cortex microvessels
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Italy
    J Histochem Cytochem 50:1671-6. 2002
  8. ncbi request reprint Expression of caveolin-1 in human brain microvessels
    D Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, I 70124 Bari, Italy
    Neuroscience 115:145-52. 2002
  9. ncbi request reprint Immunogold cytochemistry of the blood-brain barrier glucose transporter GLUT1 and endogenous albumin in the developing human brain
    D Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, I 70124, Bari, Italy
    Brain Res Dev Brain Res 123:95-101. 2000
  10. ncbi request reprint Glucose transporter GLUT1 localization in human foetus telencephalon
    D Virgintino
    Institute of Human Anatomy, Histology and Embryology, University of Bari School of Medicine, Italy
    Neurosci Lett 256:147-50. 1998

Collaborators

Detail Information

Publications27

  1. ncbi request reprint An intimate interplay between precocious, migrating pericytes and endothelial cells governs human fetal brain angiogenesis
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, 11, Bari 70124, Italy
    Angiogenesis 10:35-45. 2007
    ....
  2. ncbi request reprint Involvement of metalloprotease-2 in the development of human brain microvessels
    Francesco Girolamo
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Italy
    Histochem Cell Biol 122:261-70. 2004
    ....
  3. pmc Plasma membrane-derived microvesicles released from tip endothelial cells during vascular sprouting
    Daniela Virgintino
    Human Anatomy and Histology Unit, Department of Basic Medical Sciences, University of Bari School of Medicine, Piazza Giulio Cesare, Policlinico, 70124, Bari, Italy
    Angiogenesis 15:761-9. 2012
    ..Additional studies focused on the identification of MV content are needed to ultimately clarify the significance of tip cell MVs during human brain vascularization...
  4. ncbi request reprint Immunolocalization of tight junction proteins in the adult and developing human brain
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Bari, Italy
    Histochem Cell Biol 122:51-9. 2004
    ..This incremental process suggests more rapid establishment of the human BBB, consistent with its specific function of creating a suitable environment for neuron differentiation and neurite outgrowth during neocortical histogenesis...
  5. ncbi request reprint Fetal blood-brain barrier P-glycoprotein contributes to brain protection during human development
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy
    J Neuropathol Exp Neurol 67:50-61. 2008
    ....
  6. ncbi request reprint VEGF expression is developmentally regulated during human brain angiogenesis
    Daniela Virgintino
    Dipartimento di Anatomia Umana e di Istologia, Universita di Bari, Italy
    Histochem Cell Biol 119:227-32. 2003
    ..In these cells VEGF expression appears developmentally regulated and is correlated with angiogenesis, which in turn responds to the high metabolic demands of the differentiating neocortex...
  7. ncbi request reprint Expression of P-glycoprotein in human cerebral cortex microvessels
    Daniela Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Italy
    J Histochem Cytochem 50:1671-6. 2002
    ....
  8. ncbi request reprint Expression of caveolin-1 in human brain microvessels
    D Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, I 70124 Bari, Italy
    Neuroscience 115:145-52. 2002
    ..The demonstration of caveolin-1 in the cells of the brain microvessels suggests that caveolin-1 may be involved in blood-brain barrier functioning, and also supports co-ordinated activities between these cells...
  9. ncbi request reprint Immunogold cytochemistry of the blood-brain barrier glucose transporter GLUT1 and endogenous albumin in the developing human brain
    D Virgintino
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Piazza Giulio Cesare, I 70124, Bari, Italy
    Brain Res Dev Brain Res 123:95-101. 2000
    ..The results demonstrate that in the human foetus the brain microvessels express BBB-specific functional activities early...
  10. ncbi request reprint Glucose transporter GLUT1 localization in human foetus telencephalon
    D Virgintino
    Institute of Human Anatomy, Histology and Embryology, University of Bari School of Medicine, Italy
    Neurosci Lett 256:147-50. 1998
    ..Our findings demonstrate both the expression and subcellular localization of GLUT1 be developmentally regulated and suggest an early functioning of the BBB-GLUT1 transporter in the developing human brain...
  11. ncbi request reprint Non-traditional large neurons in the granular layer of the cerebellar cortex
    G Ambrosi
    Dipartimento di Anatomia umana e Istologia, Policlinico, Universita di Bari, Italy
    Eur J Histochem 51:59-64. 2007
    ..Finally, the perivascular neuron may intervene in the intrinsic regulation of the cortex microcirculation...
  12. ncbi request reprint Astroglia-microvessel relationship in the developing human telencephalon
    D Virgintino
    Institute of Human Anatomy, Histology and Embryology, University of Bari Medical School, Italy
    Int J Dev Biol 42:1165-8. 1998
    ....
  13. ncbi request reprint Cholinergic nerve fibres associated with the microvessels of the human cerebral cortex: a study based on monoclonal immunocytochemistry for choline acetyltrasferase
    V Benagiano
    Istituto di Anatomia Umana Normale, Facolta di Medicina e Chirurgia, Universita degli Studi di Bari, Policlinico, Italy
    Eur J Histochem 44:165-9. 2000
    ..The morphological data support the involvement of acetylcholine in microvasculature local regulation, possibly with a differentiated role in the arterioles and capillaries...
  14. ncbi request reprint Immunolocalization of glutamic acid decarboxylase in postmortem human cerebellar cortex. A light microscopy study
    V Benagiano
    Department of Human Anatomy and Histology, University of Bari, Policlinico, Italy
    Histochem Cell Biol 114:191-5. 2000
    ..The use of immunocytochemistry in the detection of GAD in the postmortem human brain greatly increases the possibility of carrying out morphological studies on the GABAergic system, both in normal and in pathological conditions...
  15. ncbi request reprint Glutamic acid decarboxylase immunoreactive large neuron types in the granular layer of the human cerebellar cortex
    P Flace
    Dipartimento di Anatomia umana e Istologia, Facolta di Medicina e Chirurgia, Universita di Bari, 70124 Bari, Italy
    Anat Embryol (Berl) 208:55-64. 2004
    ..These morphological data further point out possible functional roles for GABA as a neurotransmitter/neuromodulator in intrinsic, associative and projective circuits of the cerebellar cortex...
  16. ncbi request reprint Developmental effects of lead acetate on the chick embryo metanephros
    M Errede
    Department of Human Anatomy and Histology, University of Bari, Italy
    J Submicrosc Cytol Pathol 33:261-73. 2001
    ....
  17. ncbi request reprint Choline acetyltransferase-containing neurons in the human parietal neocortex
    V Benagiano
    Dipartimento di Anatomia Umana e Istologia Policlinico, Piazza Giulio Cesare, 70124 Bari, Italy
    Eur J Histochem 47:253-6. 2003
    ..It is likely that these neurons contribute to the cholinergic innervation of the intracortical microvessels...
  18. ncbi request reprint Characterization of oligodendrocyte lineage precursor cells in the mouse cerebral cortex: a confocal microscopy approach to demyelinating diseases
    Francesco Girolamo
    Dipartimento di Anatomia Umana e di Istologia Rodolfo Amprino, Facoltà di Medicina e Chirurgia Policlinico Università di Bari, Italia
    Ital J Anat Embryol 115:95-102. 2010
    ....
  19. ncbi request reprint Effects of 6-aminonicotinamide gliotoxin on blood-brain barrier differentiation in the chick embryo cerebellum
    Mirella Bertossi
    Department of Biomedical Sciences, University of Foggia Medical School, Foggia, Italy
    Anat Embryol (Berl) 207:209-19. 2003
    ....
  20. ncbi request reprint Differential expression of connexin43 in foetal, adult and tumour-associated human brain endothelial cells
    Mariella Errede
    Department of Human Anatomy and Histology, University of Bari Medical School, Polyclinics, Piazza Giulio Cesare, 70124 Bari, Italy
    Histochem J 34:265-71. 2002
    ..In conclusion, the results indicate that endothelial Cx43 expression is developmentally regulated in the normal human brain and suggest that it is controlled by the microenvironment in both normal and tumour-related conditions...
  21. doi request reprint Overexpression of autophagic proteins in the skeletal muscle of sporadic inclusion body myositis
    F Girolamo
    Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari School of Medicine, Bari, Italy
    Neuropathol Appl Neurobiol 39:736-49. 2013
    ..When autophagy is blocked aggregates accumulate, resulting in abnormal rimmed vacuole formation. This study investigated the autophagy-lysosome pathway contribution to rimmed vacuole accumulation...
  22. ncbi request reprint Ultrastructural and morphometric investigation of human brain capillaries in normal and peritumoral tissues
    M Bertossi
    Istituto di Anatomia Umana, Istologia ed Embriologia, , Policlinico, Italy
    Ultrastruct Pathol 21:41-9. 1997
    ..The kind and severity of the vascular modifications, compared with the slight edematous appearance of the nervous tissue, strengthen the hypothesis that peritumoral capillaries could be involved in the edema resolution process...
  23. ncbi request reprint In vivo assessment of epichlorohydrin effects: the chorioallantoic membrane model
    Francesco Girolamo
    Department of Human Anatomy and Histology, University of Bari School of Medicine, Bari, Italy
    Med Sci Monit 12:BR21-27. 2006
    ..To gain a better understanding of ECH effects in vivo, the substance was tested on developing tissues utilizing the chick embryo chorioallantoic membrane (CAM) assay...
  24. pmc Reversal of cellular roles in angiogenesis: implications for anti-angiogenic therapy
    Daniela Virgintino
    La Jolla Institute for Molecular Medicine, San Diego, Calif, USA
    J Vasc Res 45:129-31. 2008
  25. doi request reprint Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins
    Hideyuki Ishihara
    Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland
    J Neuropathol Exp Neurol 67:435-48. 2008
    ....
  26. ncbi request reprint Transgenic mice expressing F3/contactin from the TAG-1 promoter exhibit developmentally regulated changes in the differentiation of cerebellar neurons
    Antonella Bizzoca
    Dipartimento di Farmacologia e Fisiologia Umana, Universita di Torino, Italy
    Development 130:29-43. 2003
    ..Together, these findings indicate that precise spatio-temporal regulation of TAG-1 and F3/contactin expression is critical for normal cerebellar morphogenesis...
  27. ncbi request reprint Developmental changes of HT7 expression in the microvessels of the chick embryo brain
    Mirella Bertossi
    Department of Clinical and Basic Medical Sciences, University of Foggia Medical School, viale L Pinto, 71100 Foggia, Italy
    Anat Embryol (Berl) 205:229-33. 2002
    ....