Alessandro Viganò

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. pmc Efficacy and safety of a dual boosted protease inhibitor-based regimen, atazanavir and fosamprenavir/ritonavir, against HIV: experience in a pediatric population
    Stefano Rusconi
    Department of Biomedical and Clinical Science Luigi Sacco, Infectious Diseases, University of Milan, Milan, Italy
    BMC Infect Dis 12:179. 2012
  2. pmc Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy
    Elena Chiappini
    Department of Pediatrics, University of Florence, Florence, Italy
    BMC Infect Dis 9:140. 2009
  3. ncbi Successful rescue therapy with a darunavir/ritonavir and etravirine antiretroviral regimen in a child with vertically acquired multidrug-resistant HIV-1
    Alessandra Vigano
    Luigi Sacco Hospital, University of Milan, Milan, Italy
    Antivir Ther 13:839-43. 2008
  4. doi Long-term evaluation of glucose homeostasis in a cohort of HAART-treated HIV-infected children: a longitudinal, observational cohort study
    Alessandra Vigano
    Pediatric Clinic, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 29:101-9. 2009
  5. doi Metabolic complications associated with antiretroviral therapy in HIV-infected and HIV-exposed uninfected paediatric patients
    Alessandra Vigano
    Universita di Milano, Luigi Sacco Hospital, Department of Pediatrics, Milan, Italy
    Expert Opin Drug Saf 9:431-45. 2010
  6. ncbi Both HIV-infection and long-term antiretroviral therapy are associated with increased common carotid intima-media thickness in HIV-infected adolescents and young adults
    Alessandra Vigano
    Department of Pediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Curr HIV Res 8:411-7. 2010
  7. doi Long-term renal safety of tenofovir disoproxil fumarate in vertically HIV-infected children, adolescents and young adults: a 60-month follow-up study
    Alessandra Vigano
    Department of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 31:407-15. 2011
  8. pmc Long-term immunogenicity after one and two doses of a monovalent MF59-adjuvanted A/H1N1 Influenza virus vaccine coadministered with the seasonal 2009-2010 nonadjuvanted Influenza virus vaccine in HIV-infected children, adolescents, and young adults in a r
    Alessandra Vigano
    Pediatric Clinic, L Sacco Hospital, University of Milan, G B Grassi, 74 20157 Milan, Italy
    Clin Vaccine Immunol 18:1503-9. 2011
  9. ncbi Renal safety of tenofovir in HIV-infected children: a prospective, 96-week longitudinal study
    A Vigano
    Clinic of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 27:573-81. 2007
  10. ncbi Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children
    Alessandra Vigano
    L Sacco Hospital, University of Milan, Italy
    Antivir Ther 10:917-24. 2005

Collaborators

Detail Information

Publications26

  1. pmc Efficacy and safety of a dual boosted protease inhibitor-based regimen, atazanavir and fosamprenavir/ritonavir, against HIV: experience in a pediatric population
    Stefano Rusconi
    Department of Biomedical and Clinical Science Luigi Sacco, Infectious Diseases, University of Milan, Milan, Italy
    BMC Infect Dis 12:179. 2012
    ....
  2. pmc Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy
    Elena Chiappini
    Department of Pediatrics, University of Florence, Florence, Italy
    BMC Infect Dis 9:140. 2009
    ..Nevertheless, data about long-term follow-up of early treated children are lacking...
  3. ncbi Successful rescue therapy with a darunavir/ritonavir and etravirine antiretroviral regimen in a child with vertically acquired multidrug-resistant HIV-1
    Alessandra Vigano
    Luigi Sacco Hospital, University of Milan, Milan, Italy
    Antivir Ther 13:839-43. 2008
    ..The use of experimental agents might become a compelling issue in vertically HIV-infected children born in the era of highly active ART...
  4. doi Long-term evaluation of glucose homeostasis in a cohort of HAART-treated HIV-infected children: a longitudinal, observational cohort study
    Alessandra Vigano
    Pediatric Clinic, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 29:101-9. 2009
    ..In addition, we investigated possible risk factors, both related and unrelated to antiretroviral therapy, associated with insulin resistance...
  5. doi Metabolic complications associated with antiretroviral therapy in HIV-infected and HIV-exposed uninfected paediatric patients
    Alessandra Vigano
    Universita di Milano, Luigi Sacco Hospital, Department of Pediatrics, Milan, Italy
    Expert Opin Drug Saf 9:431-45. 2010
    ..Therefore, researches aiming to evaluate the safety of ARV therapies in HIV-infected children as well as in HIV-uninfected infants born to HIV-infected mothers are emerging as a new challenge and urgent priority...
  6. ncbi Both HIV-infection and long-term antiretroviral therapy are associated with increased common carotid intima-media thickness in HIV-infected adolescents and young adults
    Alessandra Vigano
    Department of Pediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Curr HIV Res 8:411-7. 2010
    ..To evaluate common carotid artery intima-media thickness (CCIMT) and cardiovascular risk factors in HIV-infected adolescents on combination antiretroviral therapy (cART)...
  7. doi Long-term renal safety of tenofovir disoproxil fumarate in vertically HIV-infected children, adolescents and young adults: a 60-month follow-up study
    Alessandra Vigano
    Department of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 31:407-15. 2011
    ..We assessed the long-term renal safety of TDF in a cohort of vertically HIV-infected children, adolescents and young adults...
  8. pmc Long-term immunogenicity after one and two doses of a monovalent MF59-adjuvanted A/H1N1 Influenza virus vaccine coadministered with the seasonal 2009-2010 nonadjuvanted Influenza virus vaccine in HIV-infected children, adolescents, and young adults in a r
    Alessandra Vigano
    Pediatric Clinic, L Sacco Hospital, University of Milan, G B Grassi, 74 20157 Milan, Italy
    Clin Vaccine Immunol 18:1503-9. 2011
    ..In HIV-infected children, adolescents, and young adults, the immune response triggered by a single dose of PV was similar to that obtained with a double dose and was associated with long-term antibody response...
  9. ncbi Renal safety of tenofovir in HIV-infected children: a prospective, 96-week longitudinal study
    A Vigano
    Clinic of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Clin Drug Investig 27:573-81. 2007
    ..The aims of this study were to assess renal safety and GFR changes as estimated by the Schwartz and Cockcroft-Gault equations in HIV-infected children treated with tenofovir for 96 weeks...
  10. ncbi Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children
    Alessandra Vigano
    L Sacco Hospital, University of Milan, Italy
    Antivir Ther 10:917-24. 2005
    ..To assess the impact on immunological, virological and metabolic parameters of replacing protease inhibitors (PIs) with efavirenz and replacing stavudine with tenofovir in HIV-infected children...
  11. ncbi Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz
    Alessandro Viganò
    Department of Paediatrics, L Sacco Hospital, University of Milan, Italy
    Antivir Ther 12:297-302. 2007
    ..We assess the effect on body composition parameters of replacing stavudine with tenofovir and protease inhibitor with efavirenz in paediatric patients...
  12. ncbi Efficacy and tolerability of multiple drug therapy in HIV-infected children
    Alessandra Vigano
    Clinica Pediatrica, L Sacco Hospital, University of Milan, Via G B Grassi 74, 20153 Milano, Italy
    J Infect 50:404-11. 2005
    ..To characterize the efficacy and tolerability of multiple drug therapy (MDT) among heavily pre-treated HIV-infected children...
  13. ncbi Nucleoside analogues toxicities related to mitochondrial dysfunction: focus on HIV-infected children
    Alessandra Vigano
    Paediatrics, L Sacco Hospital, University of Milan, Italy
    Antivir Ther 10:M53-64. 2005
  14. doi Is the interruption of antiretroviral treatment during pregnancy an additional major risk factor for mother-to-child transmission of HIV type 1?
    Luisa Galli
    Department of Pediatrics, University of Florence, Italy
    Clin Infect Dis 48:1310-7. 2009
    ..However, this recommendation is poorly supported by data. We evaluated the effects of discontinuing ART during pregnancy on the rate of mother-to-child transmission...
  15. doi Humoral and cellular response to influenza vaccine in HIV-infected children with full viroimmunologic response to antiretroviral therapy
    Alessandra Vigano
    Clinic of Pediatrics, Luigi Sacco Hospital, University of Milan, Milan, Italy
    J Acquir Immune Defic Syndr 48:289-96. 2008
    ..We evaluated the influenza-specific immune responses elicited by a virosomal vaccine in HIV-infected children on long-term successful highly active antiretroviral therapy (HAART)...
  16. doi Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza
    Antonella Amendola
    Universita degli Studi di Milano, Dipartimento di Sanità Pubblica Microbiologia Virologia, Via Pascal 36, 20133 Milan, Italy
    Vaccine 28:2700-4. 2010
    ..Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination...
  17. ncbi Long-term immunogenicity of a virosomal subunit inactivated influenza vaccine in children with asthma
    Gianvincenzo Zuccotti
    Department of Pediatrics, University of Milan, Luigi Sacco Hospital, Via GB Grassi 74, 20157 Milan, Italy
    Vaccine 25:6692-8. 2007
    ..However, while immunity response and persistence are excellently high in children with pre-existing antibodies, in children naive for the antigens the immune parameters are lower at 6 months after vaccination...
  18. ncbi Changing patterns of clinical events in perinatally HIV-1-infected children during the era of HAART
    Elena Chiappini
    Department of Paediatrics, University of Florence, Via Luca Giordano 13, I 50132 Florence, Italy
    AIDS 21:1607-15. 2007
    ..The introduction of HAART has decreased mortality and progression to AIDS in perinatally HIV-1-infected children, but information on modification of the rate of specific clinical events is limited...
  19. ncbi Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study by the Italian Register for HIV Infection in Children
    Elena Chiappini
    Department of Pediatrics, University of Florence, Florence, Italy
    J Clin Oncol 25:97-101. 2007
    ..To evaluate the impact of highly active antiretroviral therapy (HAART) on cancer incidence in HIV-infected children throughout a 20-year period...
  20. ncbi Immune activation and normal levels of endogenous antivirals are seen in healthy adolescents born of HIV-infected mothers
    Alessandra Vigano
    Department of Pediatrics, Luigi Sacco Hospital, Milan, Italy
    AIDS 21:245-8. 2007
    ..Endogenous antivirals (APOBEC, TRIM5alpha) were comparable in seroreverters and HC, and might not play a role in resistance to vertical HIV infection...
  21. ncbi Growth hormone in T-lymphocyte thymic and postthymic development: a study in HIV-infected children
    Alessandra Vigano
    Pediatrics and Immunology, Milano University, Milan, Italy
    J Pediatr 145:542-8. 2004
    ....
  22. ncbi Antiretroviral therapy and bone mineral measurements in HIV-infected youths
    Gianvincenzo Zuccotti
    Department of Pediatrics, L Sacco Hospital, University of Milan, Milan, Italy
    Bone 46:1633-8. 2010
    ..The use of antiretroviral regimens including these drugs should thus be monitored closely in HIV-infected youths...
  23. ncbi Modulation of innate and adaptive immunity by lactoferrin in human immunodeficiency virus (HIV)-infected, antiretroviral therapy-naïve children
    Gian Vincenzo Zuccotti
    Paediatrics, University of Milan, Milan, Italy
    Int J Antimicrob Agents 29:353-5. 2007
    ..009), Toll-like receptor 2 expression (P=0.01) and the interleukin-12/interleukin-10 ratio (P=0.001) were also improved by lactoferrin. Lactoferrin supplementation results in immune modulation and could be useful in HIV infection...
  24. ncbi Alterations in circulating osteoimmune factors may be responsible for high bone resorption rate in HIV-infected children and adolescents
    Stefano Mora
    Laboratory of Pediatric Endocrinology and BoNetwork, San Raffaele Scientific Institute, Milan, Italy
    AIDS 21:1129-35. 2007
    ..We investigated the possible role of RANKL and osteoprotegerin on bone metabolism alterations in paediatric patients...
  25. ncbi Applicability of quantitative ultrasonography of the radius and tibia in HIV-infected children and adolescents
    Stefano Mora
    Laboratory of Pediatric Endocrinology, Pediatric Bone Densitometry Service and BoNetwork, San Raffaele Scientific Institute, Milan, Italy
    J Acquir Immune Defic Syndr 51:588-92. 2009
    ..To assess applicability of quantitative ultrasonography (QUS) for bone health assessment in HIV-infected youths...