Research Topics
| Alessandro ViganòSummaryAffiliation: University of Milan Country: Italy Publications
| Collaborators
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Detail Information
Publications
Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapyElena Chiappini
Department of Pediatrics, University of Florence, Florence, Italy
BMC Infect Dis 9:140. 2009..Nevertheless, data about long-term follow-up of early treated children are lacking...- Long-term immunogenicity after one and two doses of a monovalent MF59-adjuvanted A/H1N1 Influenza virus vaccine coadministered with the seasonal 2009-2010 nonadjuvanted Influenza virus vaccine in HIV-infected children, adolescents, and young adults in a rAlessandra Vigano
Pediatric Clinic, L Sacco Hospital, University of Milan, G B Grassi, 74 20157 Milan, Italy
Clin Vaccine Immunol 18:1503-9. 2011..In HIV-infected children, adolescents, and young adults, the immune response triggered by a single dose of PV was similar to that obtained with a double dose and was associated with long-term antibody response... 
Long-term evaluation of glucose homeostasis in a cohort of HAART-treated HIV-infected children: a longitudinal, observational cohort studyAlessandra Vigano
Pediatric Clinic, L Sacco Hospital, University of Milan, Milan, Italy
Clin Drug Investig 29:101-9. 2009..In addition, we investigated possible risk factors, both related and unrelated to antiretroviral therapy, associated with insulin resistance...
Renal safety of tenofovir in HIV-infected children: a prospective, 96-week longitudinal studyA Vigano
Clinic of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
Clin Drug Investig 27:573-81. 2007..The aims of this study were to assess renal safety and GFR changes as estimated by the Schwartz and Cockcroft-Gault equations in HIV-infected children treated with tenofovir for 96 weeks...- Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenzAlessandro Viganò
Department of Paediatrics, L Sacco Hospital, University of Milan, Italy
Antivir Ther 12:297-302. 2007..We assess the effect on body composition parameters of replacing stavudine with tenofovir and protease inhibitor with efavirenz in paediatric patients... - Metabolic complications associated with antiretroviral therapy in HIV-infected and HIV-exposed uninfected paediatric patientsAlessandra Vigano
Universita di Milano, Luigi Sacco Hospital, Department of Pediatrics, Milan, Italy
Expert Opin Drug Saf 9:431-45. 2010..Therefore, researches aiming to evaluate the safety of ARV therapies in HIV-infected children as well as in HIV-uninfected infants born to HIV-infected mothers are emerging as a new challenge and urgent priority... - Both HIV-infection and long-term antiretroviral therapy are associated with increased common carotid intima-media thickness in HIV-infected adolescents and young adultsAlessandra Vigano
Department of Pediatrics, L Sacco Hospital, University of Milan, Milan, Italy
Curr HIV Res 8:411-7. 2010..To evaluate common carotid artery intima-media thickness (CCIMT) and cardiovascular risk factors in HIV-infected adolescents on combination antiretroviral therapy (cART)... - Long-term renal safety of tenofovir disoproxil fumarate in vertically HIV-infected children, adolescents and young adults: a 60-month follow-up studyAlessandra Vigano
Department of Paediatrics, L Sacco Hospital, University of Milan, Milan, Italy
Clin Drug Investig 31:407-15. 2011..We assessed the long-term renal safety of TDF in a cohort of vertically HIV-infected children, adolescents and young adults... - Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected childrenAlessandra Vigano
L Sacco Hospital, University of Milan, Italy
Antivir Ther 10:917-24. 2005..To assess the impact on immunological, virological and metabolic parameters of replacing protease inhibitors (PIs) with efavirenz and replacing stavudine with tenofovir in HIV-infected children... - Nucleoside analogues toxicities related to mitochondrial dysfunction: focus on HIV-infected childrenAlessandra Vigano
Paediatrics, L Sacco Hospital, University of Milan, Italy
Antivir Ther 10:M53-64. 2005 - Efficacy and tolerability of multiple drug therapy in HIV-infected childrenAlessandra Vigano
Clinica Pediatrica, L Sacco Hospital, University of Milan, Via G B Grassi 74, 20153 Milano, Italy
J Infect 50:404-11. 2005..To characterize the efficacy and tolerability of multiple drug therapy (MDT) among heavily pre-treated HIV-infected children... - Successful rescue therapy with a darunavir/ritonavir and etravirine antiretroviral regimen in a child with vertically acquired multidrug-resistant HIV-1Alessandra Vigano
Luigi Sacco Hospital, University of Milan, Milan, Italy
Antivir Ther 13:839-43. 2008..The use of experimental agents might become a compelling issue in vertically HIV-infected children born in the era of highly active ART... - Is the interruption of antiretroviral treatment during pregnancy an additional major risk factor for mother-to-child transmission of HIV type 1?Luisa Galli
Department of Pediatrics, University of Florence, Italy
Clin Infect Dis 48:1310-7. 2009..However, this recommendation is poorly supported by data. We evaluated the effects of discontinuing ART during pregnancy on the rate of mother-to-child transmission... - Humoral and cellular response to influenza vaccine in HIV-infected children with full viroimmunologic response to antiretroviral therapyAlessandra Vigano
Clinic of Pediatrics, Luigi Sacco Hospital, University of Milan, Milan, Italy
J Acquir Immune Defic Syndr 48:289-96. 2008..We evaluated the influenza-specific immune responses elicited by a virosomal vaccine in HIV-infected children on long-term successful highly active antiretroviral therapy (HAART)... - Long-term immunogenicity of a virosomal subunit inactivated influenza vaccine in children with asthmaGianvincenzo Zuccotti
Department of Pediatrics, University of Milan, Luigi Sacco Hospital, Via GB Grassi 74, 20157 Milan, Italy
Vaccine 25:6692-8. 2007..However, while immunity response and persistence are excellently high in children with pre-existing antibodies, in children naive for the antigens the immune parameters are lower at 6 months after vaccination... - Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenzaAntonella Amendola
Universita degli Studi di Milano, Dipartimento di Sanità Pubblica Microbiologia Virologia, Via Pascal 36, 20133 Milan, Italy
Vaccine 28:2700-4. 2010..Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination... - Changing patterns of clinical events in perinatally HIV-1-infected children during the era of HAARTElena Chiappini
Department of Paediatrics, University of Florence, Via Luca Giordano 13, I 50132 Florence, Italy
AIDS 21:1607-15. 2007..The introduction of HAART has decreased mortality and progression to AIDS in perinatally HIV-1-infected children, but information on modification of the rate of specific clinical events is limited... - Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study by the Italian Register for HIV Infection in ChildrenElena Chiappini
Department of Pediatrics, University of Florence, Florence, Italy
J Clin Oncol 25:97-101. 2007..To evaluate the impact of highly active antiretroviral therapy (HAART) on cancer incidence in HIV-infected children throughout a 20-year period... - Immune activation and normal levels of endogenous antivirals are seen in healthy adolescents born of HIV-infected mothersAlessandra Vigano
Department of Pediatrics, Luigi Sacco Hospital, Milan, Italy
AIDS 21:245-8. 2007..Endogenous antivirals (APOBEC, TRIM5alpha) were comparable in seroreverters and HC, and might not play a role in resistance to vertical HIV infection... - Growth hormone in T-lymphocyte thymic and postthymic development: a study in HIV-infected childrenAlessandra Vigano
Pediatrics and Immunology, Milano University, Milan, Italy
J Pediatr 145:542-8. 2004..Immunomodulant agents (including GH) could be useful in patients with defective GH production... - Antiretroviral therapy and bone mineral measurements in HIV-infected youthsGianvincenzo Zuccotti
Department of Pediatrics, L Sacco Hospital, University of Milan, Milan, Italy
Bone 46:1633-8. 2010..The use of antiretroviral regimens including these drugs should thus be monitored closely in HIV-infected youths... - Alterations in circulating osteoimmune factors may be responsible for high bone resorption rate in HIV-infected children and adolescentsStefano Mora
Laboratory of Pediatric Endocrinology and BoNetwork, San Raffaele Scientific Institute, Milan, Italy
AIDS 21:1129-35. 2007..We investigated the possible role of RANKL and osteoprotegerin on bone metabolism alterations in paediatric patients... - Modulation of innate and adaptive immunity by lactoferrin in human immunodeficiency virus (HIV)-infected, antiretroviral therapy-naïve childrenGian Vincenzo Zuccotti
Paediatrics, University of Milan, Milan, Italy
Int J Antimicrob Agents 29:353-5. 2007..009), Toll-like receptor 2 expression (P=0.01) and the interleukin-12/interleukin-10 ratio (P=0.001) were also improved by lactoferrin. Lactoferrin supplementation results in immune modulation and could be useful in HIV infection... - Applicability of quantitative ultrasonography of the radius and tibia in HIV-infected children and adolescentsStefano Mora
Laboratory of Pediatric Endocrinology, Pediatric Bone Densitometry Service and BoNetwork, San Raffaele Scientific Institute, Milan, Italy
J Acquir Immune Defic Syndr 51:588-92. 2009..To assess applicability of quantitative ultrasonography (QUS) for bone health assessment in HIV-infected youths...