Alberto Verrotti

Summary

Affiliation: University of Chieti
Country: Italy

Publications

  1. ncbi request reprint Panayiotopoulos syndrome: a consensus view
    Colin Ferrie
    Department of Paediatric Neurology, Leeds General Infirmary, Leeds LS1 3EX, UK
    Dev Med Child Neurol 48:236-40. 2006
  2. ncbi request reprint Childhood epilepsy with occipital paroxysms and benign nocturnal childhood occipital epilepsy
    A Verrotti
    Department of Paediatrics, University of Chieti, Italy
    J Child Neurol 15:218-21. 2000
  3. ncbi request reprint Serum leptin levels in girls with precocious puberty
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Diabetes Nutr Metab 16:125-9. 2003
  4. ncbi request reprint Benign focal epilepsy with onset in infancy in a patient with 18q-syndrome
    Alberto Verrotti
    Section of Pediatrics, Department of Medicine, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Childs Nerv Syst 20:362-5. 2004
  5. ncbi request reprint Insulin resistance in epileptic girls who gain weight after therapy with valproic acid
    Alberto Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    J Child Neurol 17:265-8. 2002
  6. ncbi request reprint Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Neuroendocrinology 79:157-62. 2004
  7. ncbi request reprint Photoparoxysmal responses in non-epileptic children in long-term follow-up
    A Verrotti
    Department of Medicine, Division of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Acta Neurol Scand 105:400-2. 2002
  8. ncbi request reprint Epilepsy and adolescents
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Panminerva Med 45:231-40. 2003
  9. ncbi request reprint Effect of anticonvulsant drugs on interleukins-1, -2 and -6 and monocyte chemoattractant protein-1
    A Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    Clin Exp Med 1:133-6. 2001
  10. ncbi request reprint Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy
    A Verrotti
    Department of Medicine, Division of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Epilepsy Res 48:71-5. 2002

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint Panayiotopoulos syndrome: a consensus view
    Colin Ferrie
    Department of Paediatric Neurology, Leeds General Infirmary, Leeds LS1 3EX, UK
    Dev Med Child Neurol 48:236-40. 2006
    ..We conclude that PS is a common idiopathic, benign seizure disorder of childhood, which should be classified as an autonomic epilepsy, rather than an occipital epilepsy...
  2. ncbi request reprint Childhood epilepsy with occipital paroxysms and benign nocturnal childhood occipital epilepsy
    A Verrotti
    Department of Paediatrics, University of Chieti, Italy
    J Child Neurol 15:218-21. 2000
    ..Therefore, although childhood epilepsy with occipital paroxysms and benign nocturnal childhood occipital epilepsy are two different types of epilepsy, the long-term prognosis seems to be similar...
  3. ncbi request reprint Serum leptin levels in girls with precocious puberty
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Diabetes Nutr Metab 16:125-9. 2003
    ....
  4. ncbi request reprint Benign focal epilepsy with onset in infancy in a patient with 18q-syndrome
    Alberto Verrotti
    Section of Pediatrics, Department of Medicine, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Childs Nerv Syst 20:362-5. 2004
    ..The EEGs performed during sleep showed low-voltage spikes over the fronto-central region of the left hemisphere. The magnetic resonance imaging of the brain was normal...
  5. ncbi request reprint Insulin resistance in epileptic girls who gain weight after therapy with valproic acid
    Alberto Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    J Child Neurol 17:265-8. 2002
    ..Therefore, these obese patients could be exposed to the risks related to these metabolic abnormalities; if these data are confirmed in longer studies, these side effects may raise some concerns about the safety of valproic acid...
  6. ncbi request reprint Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Neuroendocrinology 79:157-62. 2004
    ..In conclusion, the data suggest that epileptic patients who gain weight after VPA therapy have reduced plasma concentrations of antioxidant vitamins and that these reductions are reversible after VPA withdrawal...
  7. ncbi request reprint Photoparoxysmal responses in non-epileptic children in long-term follow-up
    A Verrotti
    Department of Medicine, Division of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Acta Neurol Scand 105:400-2. 2002
    ..To evaluate the photoparoxysmal responses (PPR) in non-epileptic children and adolescents in long-term follow-up...
  8. ncbi request reprint Epilepsy and adolescents
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Panminerva Med 45:231-40. 2003
    ..Some study report that the children treated with CBZ may have subclinical signs of hypothyroidism, and these changes are more evident if CBZ is given in association with another drug for example with VPA...
  9. ncbi request reprint Effect of anticonvulsant drugs on interleukins-1, -2 and -6 and monocyte chemoattractant protein-1
    A Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    Clin Exp Med 1:133-6. 2001
    ..In conclusion, antiepileptic drugs can influence the immune system by modifying interleukin and chemokine concentrations; these changes seem to be independent of the serum concentrations of these drugs...
  10. ncbi request reprint Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy
    A Verrotti
    Department of Medicine, Division of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Epilepsy Res 48:71-5. 2002
    ..In conclusion our study demonstrates that epilepsy per se and treatment with VPA and CBZ do not affect levels of Cu, Zn, Se, GSH-PX and CuZn-SOD concentrations...
  11. ncbi request reprint Color vision in epileptic adolescents treated with valproate and carbamazepine
    A Verrotti
    Division of Pediatric, Department of Medicine, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Seizure 13:411-7. 2004
    ....
  12. ncbi request reprint Serum leptin changes during weight loss in obese diabetic subjects with and without microalbuminuria
    A Verrotti
    Department of Medicine, University of Chieti, Italy
    Diabetes Nutr Metab 14:283-7. 2001
    ..The changes of leptin in diabetics seem to be similar to those observed in healthy obese subjects...
  13. ncbi request reprint Discontinuation of anticonvulsant therapy in children with partial epilepsy
    A Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    Neurology 55:1393-5. 2000
    ..8%; Group B, 25%). It is safe to discontinue the anticonvulsant therapy in children with cryptogenic partial epilepsy who were seizure free for only 1 year...
  14. ncbi request reprint Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Via dei Vestini 5, I 66100, Chieti, Italy
    Epilepsy Res 41:253-7. 2000
    ....
  15. ncbi request reprint Risk factors for recurrence of epilepsy and withdrawal of antiepileptic therapy: a practical approach
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti Ospedale Policlinico, Italy
    Ann Med 35:207-15. 2003
    ..In this review we analyse data from the literature and we suggest a practical approach for safe anticonvulsant withdrawal, although the decision should always be made individually, weighing risks and benefits...
  16. ncbi request reprint Effects of irbesartan on intracellular antioxidant enzyme expression and activity in adolescents and young adults with early diabetic angiopathy
    Francesco Chiarelli
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini, 5, I 66100 Chieti, Italy
    Diabetes Care 28:1690-7. 2005
    ..The objective of this study was to evaluate the effects of irbesartan, an angiotensin II receptor antagonist, on IAP in adolescents and young adults with type 1 diabetes and early signs of retinopathy and nephropathy...
  17. ncbi request reprint Factors associated with poor control in partial complex epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 19:262-4. 2004
    ....
  18. doi request reprint Clinical features of psychogenic non-epileptic seizures in prepubertal and pubertal patients with idiopathic epilepsy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Neurol Sci 30:319-23. 2009
    ..The findings of this study reveal some similarities and differences between prepubertal and pubertal patients, which might help to identify predictive factors in patients affected by idiopathic epilepsy who can develop PNES...
  19. doi request reprint Epilepsy in patients with Cornelia de Lange syndrome: a clinical series
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Seizure 22:356-9. 2013
    ..Epilepsy is a clinical feature found in about 20% of cases, but there are no data about its electroclinical features and long-term outcome...
  20. doi request reprint Long term outcome in children affected by absence epilepsy with onset before the age of three years
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 20:366-9. 2011
    ..The goal of this study was to define the long-term outcome of absence epilepsy presenting before the age of 3 years...
  21. doi request reprint Benign convulsions associated with mild gastroenteritis: a multicenter clinical study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Res 93:107-14. 2011
    ..To assess the clinical characteristics and the outcome of benign convulsions associated with mild gastroenteritis (CwG) in Italian children...
  22. doi request reprint Antiepileptic drugs, sex hormones, and PCOS
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 52:199-211. 2011
    ..A better understanding of the effects of AEDs on sex hormones is key to selecting the appropriate AEDs and is crucial for reproductive health in female patients...
  23. doi request reprint Increased oxidative stress in epileptic children treated with valproic acid
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Epilepsy Res 78:171-7. 2008
    ..To determine influence of Valproic Acid (VPA) treatment on oxidative status in non-obese and overweight epileptic children...
  24. doi request reprint Peri-ictal and inter-ictal headache in children and adolescents with idiopathic epilepsy: a multicenter cross-sectional study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Childs Nerv Syst 27:1419-23. 2011
    ..Headache in epileptic population ranges from 8% to 15%. The aim of this paper was to study the clinical and temporal characteristics of primary headache comorbidity in idiopathic epileptic children...
  25. doi request reprint The effect of recurrent severe hypoglycemia on cognitive performance in children with type 1 diabetes: a meta-analysis
    Annalisa Blasetti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 26:1383-91. 2011
    ..However, these results must be considered with caution taking into account factors such as small sample sizes, the different definitions of severe hypoglycemia, and the variety of neuropsychological tests used...
  26. ncbi request reprint Levetiracetam in absence epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Dev Med Child Neurol 50:850-3. 2008
    ..Prospective, large, long-term double-blind studies are needed to confirm these findings...
  27. doi request reprint Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Seizure 19:368-72. 2010
    ..We discuss the possible association between these two epileptic syndromes and its common pathophysiological mechanisms...
  28. doi request reprint Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Eur J Endocrinol 160:81-6. 2009
    ..This study evaluates the effects of long-term carbamazepine (CBZ) and valproate acid (VPA) therapy on thyroid function in epileptic children...
  29. ncbi request reprint Photosensitivity and epilepsy: a follow-up study
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti Ospedale Policlinico, Chieti, Italy
    Dev Med Child Neurol 46:347-51. 2004
    ..Thirty-three patients became seizure-free. Our study confirms that photosensitive epilepsy has a good prognosis for seizure control that is independent of the persistence or disappearance of photosensitivity...
  30. doi request reprint Lacosamide in pediatric and adult patients: comparison of efficacy and safety
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Seizure 22:210-6. 2013
    ..This multicenter, prospective study investigates the efficacy and safety of lacosamide adjunctive therapy in pediatric and adult patients with uncontrolled epilepsy...
  31. doi request reprint Could receptors for advanced glycation end products be considered cardiovascular risk markers in obese children?
    Tommaso de Giorgis
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Antioxid Redox Signal 17:187-91. 2012
    ..Our findings lead to the hypothesis that RAGE system seems to be related to the development of atherosclerosis even in obese prepubertal children...
  32. doi request reprint Valproate-induced insulin resistance and obesity in children
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Horm Res 71:125-31. 2009
    ..Among the side effects of VPA, weight gain is frequently reported, although the real incidence and magnitude of this problem is unknown. Its pathogenesis is most likely multifactorial, and is controversial...
  33. doi request reprint Should "migralepsy" be considered an obsolete concept? A multicenter retrospective clinical/EEG study and review of the literature
    Alberto Verrotti
    Child Neurology and Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 21:52-9. 2011
    ....
  34. ncbi request reprint Increased bone turnover in prepubertal, pubertal, and postpubertal patients receiving carbamazepine
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Epilepsia 43:1488-92. 2002
    ..To study the markers of bone turnover in epilepsy patients in the different stages of the pubertal growth before and after the beginning of carbamazepine (CBZ) monotherapy...
  35. ncbi request reprint von Willebrand factor and its propeptide in children with diabetes. Relation between endothelial dysfunction and microalbuminuria
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Oespedale Policlinico, Chieti, Italy
    Pediatr Res 53:382-6. 2003
    ....
  36. doi request reprint Nonalcoholic fatty liver disease in adolescents receiving valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 20:382-5. 2011
    ..The aim of this study was to investigate the association between the metabolic derangements induced by valproic acid (VPA) and ultrasound-diagnosed nonalcoholic fatty liver disease (NAFLD) in adolescents...
  37. doi request reprint Clinical dissection of early onset absence epilepsy in children and prognostic implications
    Sergio Agostinelli
    Child Epilepsy Center, Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 54:1761-70. 2013
    ....
  38. doi request reprint The possible role of esRAGE and sRAGE in the natural history of diabetic nephropathy in childhood
    Cosimo Giannini
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100, Chieti, Italy
    Pediatr Nephrol 27:269-75. 2012
    ..The inverse association between esRAGE levels and early kidney alterations suggests a potential role of esRAGE in diabetic nephropathy...
  39. doi request reprint The metabolic syndrome in overweight epileptic patients treated with valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 51:268-73. 2010
    ..To evaluate the presence of metabolic syndrome (MS) in children and adolescents treated with valproate (VPA)...
  40. ncbi request reprint Intermittent oral diazepam prophylaxis in febrile convulsions: its effectiveness for febrile seizure recurrence
    Alberto Verrotti
    Section of Pediatrics, Department of Medicine, University of Chieti Ospedale Policlinico, Via dei Vestini 5, Chieti 66013, Italy
    Eur J Paediatr Neurol 8:131-4. 2004
    ..7%) went on to have one or more additional episodes. In conclusion, our study demonstrates that oral diazepam, given only when fever is present, is an effective means of reducing the risk of recurrences of FS...
  41. doi request reprint Variables associated with severe hypoglycemia in children and adolescents with type 1 diabetes: a population-based study
    Annalisa Blasetti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, Chieti, Italy
    Pediatr Diabetes 12:4-10. 2011
    ..The aim of our study was to determine the incidence of SH and associated variables in a population of children and adolescents with T1DM...
  42. doi request reprint Hormonal and reproductive disturbances in epileptic male patients: emerging issues
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Reprod Toxicol 31:519-27. 2011
    ..To review the relationship between epilepsy, antiepileptic drugs and reproductive function...
  43. doi request reprint Valproate in adolescents with photosensitive epilepsy with generalized tonic-clonic seizures only
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy Department of Pediatrics, University of Perugia, Perugia, Italy
    Eur J Paediatr Neurol 18:13-8. 2014
    ..To assess the effects of valproate (VPA) on seizure response/control and photosensitivity (PS) in adolescents suffering from photosensitive epilepsy with generalized tonic-clonic seizures only (EGTCS)...
  44. doi request reprint Neuropsychological impairment in children with Rolandic epilepsy and in their siblings
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 28:108-12. 2013
    ..A similar neuropsychological profile of RE, which affected patients and their siblings with impairment in the same developing areas, supports the hypothesis of a specific neurocognitive phenotype in RE...
  45. doi request reprint Obese children suffer more often from migraine
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Acta Paediatr 101:e416-21. 2012
    ..To determine a possible relationship between migraine and body mass index...
  46. doi request reprint Long-term outcome of epilepsy in Kabuki syndrome
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Seizure 20:650-4. 2011
    ..Therefore, we describe here a clinical series of 10 Caucasian KS patients who developed epilepsy in childhood. We followed all children for at least 5 years...
  47. doi request reprint What is the significance of soluble and endogenous secretory receptor for advanced glycation end products in liver steatosis in obese prepubertal children?
    Ebe D'Adamo
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Antioxid Redox Signal 14:1167-72. 2011
    ..These findings suggest that AGE-RAGE pathway plays an independent role in the development of liver injury already present in this age group...
  48. doi request reprint Paroxysmal tonic upgaze of childhood and childhood absence epilepsy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Eur J Paediatr Neurol 14:93-6. 2010
    ..Our case suggests a possible association between PTU and epilepsy...
  49. doi request reprint Weight gain and insulin resistance in children treated with valproate: the influence of time
    Fabio Masuccio
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 25:941-7. 2010
    ..These results might be helpful to enhance the knowledge of valproic acid action on both insulin resistance and weight gain, allowing to plan appropriate approach for the prevention of the consequences of the treatment with valproic acid...
  50. doi request reprint GNRH analog therapy in girls with early puberty is associated with the achievement of predicted final height but also with increased risk of polycystic ovary syndrome
    Valentina Chiavaroli
    Departments of Pediatrics Obstetrics and Gynecology University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Eur J Endocrinol 163:55-62. 2010
    ..Women with PCOS are at increased risk of cardiometabolic dysfunctions and infertility. Our aim was to assess GNRHa effectiveness on reaching adult stature and the risk of PCOS in girls with early puberty...
  51. doi request reprint Catamenial epilepsy: hormonal aspects
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Gynecol Endocrinol 26:783-90. 2010
    ..Also, variations in concentrations of antiepileptic drugs across the menstrual cycle may contribute to increased seizure susceptibility. A variety of approaches have been proposed for the treatment of catamenial epilepsy...
  52. doi request reprint Topiramate-induced weight loss: a review
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66013 Chieti, Italy
    Epilepsy Res 95:189-99. 2011
    ..In international literature, the reported body weight loss incidences linked to TPM therapy vary widely and, in some cases, are very conflicting...
  53. doi request reprint Early-onset pure absence epilepsy: a distinct epileptic syndrome
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Acta Paediatr 100:647-50. 2011
    ..This review summarizes the current understanding on this epilepsy...
  54. doi request reprint Reflex myoclonic epilepsy in infancy: a multicenter clinical study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Res 103:237-44. 2013
    ..To describe the clinical and electroencephalographic (EEG) features of reflex myoclonic epilepsy in infancy (RMEI) and long-term cognitive outcome...
  55. doi request reprint Photosensitivity: epidemiology, genetics, clinical manifestations, assessment, and management
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Epileptic Disord 14:349-62. 2012
    ..Published with video sequences]...
  56. ncbi request reprint Effects of vitamin E supplementation on intracellular antioxidant enzyme production in adolescents with type 1 diabetes and early microangiopathy
    Francesco Chiarelli
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini, 5, I 66100 Chieti, Italy
    Pediatr Res 56:720-5. 2004
    ..Adolescents with early signs of diabetic angiopathy have defective IAP and activity, which are not modified by vitamin E...
  57. ncbi request reprint Diabetic neuropathy in children and adolescents
    Daniela Trotta
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Diabetes 5:44-57. 2004
    ..Etiopathogenetic theories and diagnostic tools are also reviewed from in a pediatric perspective...
  58. ncbi request reprint Old and new antiepileptic drugs for the treatment of idiopathic generalized epilepsies
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66013 Chieti, Italy
    Curr Clin Pharmacol 2:249-59. 2007
    ..Today, "new" antiepileptic drugs, such as lamotrigine, levetiracetam, topiramate and zonisamide are useful tools in the treatment of pharmacoresistant epilepsies...
  59. doi request reprint Bone and calcium metabolism and antiepileptic drugs
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Clin Neurol Neurosurg 112:1-10. 2010
    ..g., valproate) cannot be readily explained by vitamin D metabolism. In this article, the literature related to the effects of classic and new antiepileptic drugs on bone health and calcium metabolism is reviewed...
  60. doi request reprint Epilepsy, sex hormones and antiepileptic drugs in female patients
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Expert Rev Neurother 9:1803-14. 2009
    ..The aim of the present review is to critically evaluate the recently published data concerning the interactions between sex hormones, epilepsy and AEDs...
  61. ncbi request reprint Preventing microvascular diabetic complications in children and adolescents: looking beyond glycaemic control
    Alberto Verrotti
    Department of Pediatrics Policlinico Colle Dell Ara, University G D Annunzio, Via dei Vestini 5, I 66013 Chieti, Italy
    Expert Opin Pharmacother 4:525-32. 2003
    ..Therapeutic interventions, particularly excellent metabolic control, may be almost effective in preventing complication onset, or significantly retarding the rate of progression...
  62. doi request reprint Pharmacotherapy for children and adolescents with epilepsy
    Alberto Verrotti
    University of Chieti, Department of Pediatrics, Ospedale Policlinico, Via dei Vestini 5, Chieti, Italy
    Expert Opin Pharmacother 12:175-94. 2011
    ..Childhood epilepsies are the most frequent neurological problems that occur in children. Despite the introduction of new antiepileptic drugs (AEDs) 25-30% of children with epilepsy remain refractory to medical therapy...
  63. ncbi request reprint Typical and atypical rolandic epilepsy in childhood: a follow-up study
    Alberto Verrotti
    Department of Pediatrics Policlinico Colle Dell Ara, University of Chieti, Via dei Vestini 5, I 66013 Chieti, Italy
    Pediatr Neurol 26:26-9. 2002
    ..5% vs 7.8%; P < 0.0001). In conclusion, atypical rolandic epilepsy seems to be associated with a high percentage of learning and behavioral disorders...
  64. ncbi request reprint Antiepileptic drugs and thyroid function
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Pediatr Endocrinol Metab 21:401-8. 2008
    ..The aim of this review is to analyse critically the principal alterations in thyroid function caused by AED therapy...
  65. doi request reprint Treatment options for paediatric diabetes
    Alberto Verrotti
    University of Chieti, Department of Pediatrics, Italy
    Expert Opin Pharmacother 11:2483-95. 2010
    ..Diabetes mellitus is the most common endocrine disease in childhood. The global incidence of diabetes emphasizes the health, social and financial magnitude of this disease and the importance of optimizing disease management and prevention...
  66. ncbi request reprint Photosensitivity and epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 19:571-8. 2004
    ..Stimulus avoidance and stimulus modification can be an effective treatment in some patients and can sometimes be combined with antiepileptic drug treatment...
  67. ncbi request reprint Endocrine and metabolic changes in epileptic patients receiving valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    J Pediatr Endocrinol Metab 18:423-30. 2005
    ....
  68. ncbi request reprint Anticonvulsant hypersensitivity syndrome in children: incidence, prevention and management
    Alberto Verrotti
    Department of Pediatrics Policlinico Colle Dell Ara, University G D Annunzio, Chieti, Italy
    CNS Drugs 16:197-205. 2002
    ..Diagnostic tests, such as patch tests or in vitro assays, for AHS could help to identify patients at risk of developing the syndrome and could represent a first step of primary prevention when applied to relatives of patients...
  69. doi request reprint Levetiracetam in childhood epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Paediatr Drugs 12:177-86. 2010
    ....
  70. ncbi request reprint Valproate-induced hyperammonemic encephalopathy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Metab Brain Dis 17:367-73. 2002
    ..Moreover, VHE seems to be more frequently in patients with carnitine deficiency or with congenital urea cycle enzymatic defects...
  71. ncbi request reprint New trends in the treatment of diabetic nephropathy in children
    Alberto Verrotti
    Department of Pediatrics, Ospedale Policlinico, Via dei Vestini, Chieti, Italy
    Expert Opin Pharmacother 3:1169-76. 2002
    ..In this review controversial aspects of this issue are presented and discussed...
  72. ncbi request reprint Extended-release formulations in epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    J Child Neurol 22:419-26. 2007
    ..The results of these studies are encouraging and suggest a good tolerability and efficacy of these extended-release formulations, although larger studies are needed...
  73. ncbi request reprint Retinal nerve fiber layer and macular thickness in adolescents with epilepsy treated with valproate and carbamazepine
    Lucio Lobefalo
    Department of Experimental Surgery, Section of Ophthalmology, University of Chieti, Italy
    Epilepsia 47:717-9. 2006
    ..To evaluate retinal nerve retinal nerve fiber layer (RNFL) and macular thickness by using optical coherence tomography (OCT) in epileptic adolescents before and during monotherapy with valproic acid (VPA) and carbamazepine (CBZ)...
  74. ncbi request reprint Recent advances on neural tube defects with special reference to Valproic Acid
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Endocr Metab Immune Disord Drug Targets 6:25-31. 2006
    ..There is strong evidence for a protective effect of adequate folate consumption...
  75. ncbi request reprint The treatment of juvenile myoclonic epilepsy
    Alberto Verrotti
    University of Chieti, Alberto Verrotti Dept of Pediatrics, University of Chieti Ospedale Policlinico, Via dei Vestini 5, Italy
    Expert Rev Neurother 6:847-54. 2006
    ..Currently, administration of new antiepileptic drugs, such as levetiracetam, lamotrigine and topiramate, seems to have beneficial effects in the patients with poor response to valproate...
  76. doi request reprint Nonalcoholic fatty liver disease during valproate therapy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, 5 66100, Chieti Italy
    Eur J Pediatr 168:1391-4. 2009
    ..The present case suggests that obesity, hyperinsulinemia, insulin resistance, and long-term treatment with VPA may be all associated with the development of NAFLD; this side effect is reversible after VPA withdrawal...
  77. ncbi request reprint Antiepileptic drugs and visual function
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Neurol 36:353-60. 2007
    ....
  78. doi request reprint Levetiracetam in juvenile myoclonic epilepsy: long-term efficacy in newly diagnosed adolescents
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Rome, Italy
    Dev Med Child Neurol 50:29-32. 2008
    ..At 12-month evaluation: 29 patients were seizure free; three patients were responders. No patients reported adverse events. These data provide preliminary evidence that LEV may be effective for treating patients with newly diagnosed JME...
  79. ncbi request reprint Endothelial dysfunction in children with type 1 diabetes mellitus
    Mariapina Pomilio
    Clinica Pediatrica, University of Chieti, Italy
    J Pediatr Endocrinol Metab 15:343-61. 2002
    ..Complete understanding of the pathophysiology of endothelial dysfunction may lead to timely therapeutic intervention to prevent its development and to slow the progression of diabetic complications...
  80. doi request reprint New trends in neuronal migration disorders
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Eur J Paediatr Neurol 14:1-12. 2010
    ..This review reports the main clinical and pathophysiological aspects of these disorders paying particular attention to the recent advances in molecular genetics...
  81. ncbi request reprint Pharmacotherapy of spasticity in children with cerebral palsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Pediatr Neurol 34:1-6. 2006
    ..The purpose of this article is to provide an overview of available oral and parenteral drugs for treatment of spasticity in cerebral palsy and to outline indications and contraindications...
  82. ncbi request reprint DI-2-ethylhexyl phthalate and endocrine disruption: a review
    Giuseppe Latini
    Division of Pediatrics, Ospedale Perrino, Brindisi, University of Chieti, and 4Neonatal Intensive Care Unit, Azienda Ospedaliera Senese, Siena, Italy
    Curr Drug Targets Immune Endocr Metabol Disord 4:37-40. 2004
    ..In particular, certain members of this chemical class, such as di-[2-ethylhexyl]-phthalate (DEHP), have been shown to cause reproductive and developmental toxicity and are suspected to be endocrine disruptors...
  83. ncbi request reprint Magnetoencephalography in pediatric neurology and in epileptic syndromes
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Neurol 28:253-61. 2003
    ..This application of magnetoencephalography is essential in the selection of epileptic children candidates to surgical treatment of seizures...
  84. ncbi request reprint Discontinuation of anticonvulsant therapy and the electroencephalogram
    Alberto Verrotti
    J Child Neurol 19:81; author reply 81-2. 2004
  85. ncbi request reprint Topiramate in children and adolescents with epilepsy and mental retardation: a prospective study on behavior and cognitive effects
    Giangennaro Coppola
    Clinic of Child Neuropsychiatry, Second University of Naples, Naples, Italy
    Epilepsy Behav 12:253-6. 2008
    ..1% of cases, respectively. In conclusion, this trial confirms that TPM can have significant adverse cognitive and behavioral side effects, even in mentally disabled children and adolescents...
  86. ncbi request reprint Bone metabolism and vitamin D levels in carbamazepine-treated patients
    Alberto Verrotti
    Epilepsia 47:1586; author reply 1586-7. 2006
  87. ncbi request reprint Hypoglycemia, hypoglycemia unawareness and counterregulation in children and adolescents with type 1 diabetes mellitus
    Ece Bober
    Department of Pediatric Endocrinology and Adolescence, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
    J Pediatr Endocrinol Metab 18:831-41. 2005
    ..In order to implement this, it is essential to organize an intensive training program with the patient and family, and to provide psychological support and close coordination with the diabetes treatment team...
  88. ncbi request reprint Role of camping in the treatment of childhood obesity
    Mario Di Pietro
    Hospital of Atri, Atri Teramo, Italy
    Acta Biomed 75:118-21. 2004
    ..These results suggest that camps may help to improve nutritional and physical education and psychological outcome of obese children...
  89. ncbi request reprint Serum insulin and leptin levels and valproate-associated obesity
    Alberto Verrotti
    Epilepsia 44:1606. 2003
  90. ncbi request reprint Autonomic status epilepticus in Panayiotopoulos syndrome and other childhood and adult epilepsies: a consensus view
    Colin D Ferrie
    Department of Paediatric Neurology, Leeds General Infirmary, United Kingdom
    Epilepsia 48:1165-72. 2007
    ..To discuss and propose a definition of autonomic status epilepticus (SE), describe its clinical and EEG features, and review what is known about its epidemiology, pathophysiology, differential diagnosis, and management...
  91. ncbi request reprint Efficacy and safety of topiramate in refractory epilepsy of childhood: long-term follow-up study
    Salvatore Grosso
    Pediatrics Department, University of Siena, Siena, Italy
    J Child Neurol 20:893-7. 2005
    ..Moreover, preliminary data seem to suggest that the efficacy of topiramate, when evaluated in the long-term perspective, is more sustained in localization-related epilepsy than in generalized epilepsy...
  92. doi request reprint Thirty-year persistence of obesity after presentation to a pediatric obesity clinic
    Lorenzo Iughetti
    Department of Pediatrics, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena 41100, Italy
    Ann Hum Biol 35:439-48. 2008
    ..Few large, long-term studies are available on the relationship between childhood and adult obesity...
  93. ncbi request reprint Early dynamic changes in pulse oximetry signals in preterm newborns with histologic chorioamnionitis
    Claudio De Felice
    Neonatal Intensive Care Unit, Azienda Ospedaliera Universitaria Senese, Policlinico Le Scotte, Siena, Italy
    Pediatr Crit Care Med 7:138-42. 2006
    ..Increasing evidence indicates myocardial dysfunctions in affected fetuses and newborns. We sought to assess the value of nonlinear dynamics from pulse oximetry signals in identifying affected newborns...
  94. ncbi request reprint Abnormal oral mucosal light reflectance in achondroplasia
    Claudio De Felice
    Hospital based Neonatologist and Clinical Researcher, Neonatal Intensive Care Unit, Azienda Ospedaliera Universitaria Senese, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:748-52. 2006
    ..4% specificity. These findings indicate the presence of previously unrecognized oral mucosal reflectance abnormalities in unaffected ACH parents of ACH children...
  95. ncbi request reprint Epileptic EEG discharges and short non-convulsive crisis: Influence on cognitive and psychobehavioural functions in youths
    Sergio Domizio
    Neonatal Intensive Care Unit, University G d Annunzio Chieti, Italy
    Clin Invest Med 31:E20-40. 2008
    ..We determined if the cognitive characteristics of epileptic children depend exclusively on illness factors, or if epileptic electroencephalogram discharges during the crisis contribute to these changes...
  96. ncbi request reprint Topiramate: its pharmacological properties and therapeutic efficacy in epilepsy
    Giuseppe Latini
    Division of Neonatology, Perrino Hospital, National Research Council of Italy, Lecce Section, s s 7 per Mesagne, 72100 Brindisi, Italy
    Mini Rev Med Chem 8:10-23. 2008
    ..This review, summarising the main studies in this field, provides an overview of the current knowledge about the relevant pharmacological and clinical information on the efficacy and tolerability of TPM...
  97. ncbi request reprint Oral mucosa spectrophotometric changes in healthy parents of patients with Down syndrome
    Giuseppe Latini
    Division of Neonatology, Ospedale Perrino, Brindisi, Italy
    Prenat Diagn 24:685-7. 2004
    ..To date, no phenotypical markers in the parents of DS offspring are known. Here, we tested the value of oral mucosal reflectance spectrophotometry in identifying unaffected parents of DS patients (free trisomy 21)...
  98. ncbi request reprint Bone mineral density in angelman syndrome
    Giangennaro Coppola
    Clinic of Child Neuropsychiatry, Second University of Naples, Naples, Italy
    Pediatr Neurol 37:411-6. 2007
    ..Dual-energy X-ray absorptiometry should be performed in all patients with Angelman syndrome, particularly if they are treated with antiepileptic drugs...
  99. ncbi request reprint Genetic polymorphisms and idiopathic generalized epilepsies
    Nazzareno Lucarini
    Department of Molecular, Cellular, and Animal Biology, University of Camerino, Camerino, Italy
    Pediatr Neurol 37:157-64. 2007
    ..We review the main genetic polymorphisms reported in idiopathic generalized epilepsy, and discusses their possible functional significance in the pathogenesis of seizures...
  100. ncbi request reprint Levetiracetam or oxcarbazepine as monotherapy in newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS): an open-label, parallel group trial
    Giangennaro Coppola
    Clinic of Child Neuropsychiatry, Second University of Naples, Italy
    Brain Dev 29:281-4. 2007
    ..These preliminary data from an open, parallel group study suggest that levetiracetam and oxcarbazepine may be potentially effective and well tolerated drugs for children with BECTS who require treatment...
  101. ncbi request reprint Infections and risk of type I diabetes in childhood: a population-based case-control study
    Emma Altobelli
    Department of Internal Medicine and Public Health, University of L Aquila, Italy
    Eur J Epidemiol 18:425-30. 2003
    ..This study focuses on the evaluation of some infectious diseases as risk determinants of type I diabetes mellitus (DM)...