Alberto Verrotti

Summary

Affiliation: University of Chieti
Country: Italy

Publications

  1. ncbi request reprint Anticonvulsant drugs and hematological disease
    A Verrotti
    Department of Pediatrics, University of Perugia, Perugia, Italy
    Neurol Sci 35:983-93. 2014
  2. ncbi request reprint Epilepsy in Prader-Willi syndrome: clinical, diagnostic and treatment aspects
    Alberto Verrotti
    Department of Pediatrics, University of Perugia, Sant Andrea delle Fratte, Perugia, Italy
    World J Pediatr 10:108-13. 2014
  3. pmc Focal epilepsy associated with glioneuronal tumors
    Giulia Loiacono
    Department of Paediatrics, University of Chieti, 66100 Chieti, Italy
    ISRN Neurol 2011:867503. 2011
  4. pmc Epilepsy and suicide: pathogenesis, risk factors, and prevention
    Alberto Verrotti
    Department of Pediatrics, Institute of Psychiatry, University G d Annunzio of Chieti Italy
    Neuropsychiatr Dis Treat 4:365-70. 2008
  5. ncbi request reprint Memory impairment and Benign Epilepsy with centrotemporal spike (BECTS): a growing suspicion
    Alberto Verrotti
    Department of Pediatrics, University of Perugia, Loc S Andrea Fratte, 06134 Perugia, Italy Electronic address
    Brain Cogn 84:123-31. 2014
  6. doi request reprint Eslicarbazepine acetate: an update on efficacy and safety in epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Perugia, Italy Electronic address
    Epilepsy Res 108:1-10. 2014
  7. pmc "Electro-clinical syndromes" with onset in paediatric age: the highlights of the clinical-EEG, genetic and therapeutic advances
    Pasquale Parisi
    NESMOS Department, Chair of Pediatrics, Child Neurology, Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa, 1035 1039, Rome, 00189, Italy
    Ital J Pediatr 37:58. 2011
  8. doi request reprint Lacosamide in pediatric and adult patients: comparison of efficacy and safety
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Seizure 22:210-6. 2013
  9. doi request reprint Reflex myoclonic epilepsy in infancy: a multicenter clinical study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Res 103:237-44. 2013
  10. doi request reprint Lacosamide in patients with pharmacoresistant epilepsy
    Alberto Verrotti
    University of Chieti, Department of Paediatrics, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Expert Opin Pharmacother 13:2065-72. 2012

Detail Information

Publications163 found, 100 shown here

  1. ncbi request reprint Anticonvulsant drugs and hematological disease
    A Verrotti
    Department of Pediatrics, University of Perugia, Perugia, Italy
    Neurol Sci 35:983-93. 2014
    ..Further research is needed to assess the real pathogenetic mechanism at the basis of hematological complications caused by AEDs...
  2. ncbi request reprint Epilepsy in Prader-Willi syndrome: clinical, diagnostic and treatment aspects
    Alberto Verrotti
    Department of Pediatrics, University of Perugia, Sant Andrea delle Fratte, Perugia, Italy
    World J Pediatr 10:108-13. 2014
    ..Consequently, there are controversial data about the clinical characteristics of epilepsy and electroencephalographic (EEG) abnormalities found in these patients...
  3. pmc Focal epilepsy associated with glioneuronal tumors
    Giulia Loiacono
    Department of Paediatrics, University of Chieti, 66100 Chieti, Italy
    ISRN Neurol 2011:867503. 2011
    ....
  4. pmc Epilepsy and suicide: pathogenesis, risk factors, and prevention
    Alberto Verrotti
    Department of Pediatrics, Institute of Psychiatry, University G d Annunzio of Chieti Italy
    Neuropsychiatr Dis Treat 4:365-70. 2008
    ..The aim of the review was to analyze the relationship between suicide and epilepsy, to identify the major risk factors, and to analyze effective treatment options...
  5. ncbi request reprint Memory impairment and Benign Epilepsy with centrotemporal spike (BECTS): a growing suspicion
    Alberto Verrotti
    Department of Pediatrics, University of Perugia, Loc S Andrea Fratte, 06134 Perugia, Italy Electronic address
    Brain Cogn 84:123-31. 2014
    ....
  6. doi request reprint Eslicarbazepine acetate: an update on efficacy and safety in epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Perugia, Italy Electronic address
    Epilepsy Res 108:1-10. 2014
    ..Additionally, it is undergoing investigation for monotherapy in subjects with partial epilepsy, and other neurological and psychiatric disorders. ..
  7. pmc "Electro-clinical syndromes" with onset in paediatric age: the highlights of the clinical-EEG, genetic and therapeutic advances
    Pasquale Parisi
    NESMOS Department, Chair of Pediatrics, Child Neurology, Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa, 1035 1039, Rome, 00189, Italy
    Ital J Pediatr 37:58. 2011
    ..Therefore, according to the age at onset, here we review the more frequently observed paediatric electro-clinical syndrome from their clinical-EEG, genetic and therapeutic point of views...
  8. doi request reprint Lacosamide in pediatric and adult patients: comparison of efficacy and safety
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Seizure 22:210-6. 2013
    ..This multicenter, prospective study investigates the efficacy and safety of lacosamide adjunctive therapy in pediatric and adult patients with uncontrolled epilepsy...
  9. doi request reprint Reflex myoclonic epilepsy in infancy: a multicenter clinical study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Res 103:237-44. 2013
    ..To describe the clinical and electroencephalographic (EEG) features of reflex myoclonic epilepsy in infancy (RMEI) and long-term cognitive outcome...
  10. doi request reprint Lacosamide in patients with pharmacoresistant epilepsy
    Alberto Verrotti
    University of Chieti, Department of Paediatrics, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Expert Opin Pharmacother 13:2065-72. 2012
    ..The efficacy, safety, tolerability and favorable pharmacokinetic profile in the adult population suggest that lacosamide could be of benefit for patients with partial-onset seizures...
  11. doi request reprint Clinical features of psychogenic non-epileptic seizures in prepubertal and pubertal patients with idiopathic epilepsy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Neurol Sci 30:319-23. 2009
    ..The findings of this study reveal some similarities and differences between prepubertal and pubertal patients, which might help to identify predictive factors in patients affected by idiopathic epilepsy who can develop PNES...
  12. doi request reprint Glut1 deficiency: when to suspect and how to diagnose?
    A Verrotti
    Department of Paediatrics, University of Chieti, Ospedale Policlinico SS Annunziata, Via dei Vestini 5, 66100 Chieti, Italy
    Eur J Paediatr Neurol 16:3-9. 2012
    ..Treatment with a ketogenic diet results in marked improvement of seizures and movement disorders. This review summarizes recent advances in understanding of GLUT1-DS and highlights the diagnostic and therapeutic approach to GLUT1-DS...
  13. ncbi request reprint Paroxysmal tonic upgaze of childhood and childhood absence epilepsy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Eur J Paediatr Neurol 14:93-6. 2010
    ..Our case suggests a possible association between PTU and epilepsy...
  14. doi request reprint The metabolic syndrome in overweight epileptic patients treated with valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 51:268-73. 2010
    ..To evaluate the presence of metabolic syndrome (MS) in children and adolescents treated with valproate (VPA)...
  15. ncbi request reprint A 12-month longitudinal study of calcium metabolism and bone turnover during valproate monotherapy
    A Verrotti
    Department of Pediatrics, Chieti University Hospital, Chieti, Italy
    Eur J Neurol 17:232-7. 2010
    ....
  16. ncbi request reprint Intermittent oral diazepam prophylaxis in febrile convulsions: its effectiveness for febrile seizure recurrence
    Alberto Verrotti
    Section of Pediatrics, Department of Medicine, University of Chieti Ospedale Policlinico, Via dei Vestini 5, Chieti 66013, Italy
    Eur J Paediatr Neurol 8:131-4. 2004
    ..7%) went on to have one or more additional episodes. In conclusion, our study demonstrates that oral diazepam, given only when fever is present, is an effective means of reducing the risk of recurrences of FS...
  17. ncbi request reprint Topiramate in frontal lobe epilepsy
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Acta Neurol Scand 115:132-5. 2007
    ..Frontal lobe epilepsy (FLE) is a type of epilepsy that is difficult to treat and there are few studies about the use of topiramate (TPM)...
  18. ncbi request reprint Bone and calcium metabolism and antiepileptic drugs
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Clin Neurol Neurosurg 112:1-10. 2010
    ..g., valproate) cannot be readily explained by vitamin D metabolism. In this article, the literature related to the effects of classic and new antiepileptic drugs on bone health and calcium metabolism is reviewed...
  19. ncbi request reprint Epilepsy, sex hormones and antiepileptic drugs in female patients
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Expert Rev Neurother 9:1803-14. 2009
    ..The aim of the present review is to critically evaluate the recently published data concerning the interactions between sex hormones, epilepsy and AEDs...
  20. doi request reprint Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Seizure 19:368-72. 2010
    ..We discuss the possible association between these two epileptic syndromes and its common pathophysiological mechanisms...
  21. ncbi request reprint Levetiracetam in childhood epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Paediatr Drugs 12:177-86. 2010
    ....
  22. doi request reprint Catamenial epilepsy: hormonal aspects
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Gynecol Endocrinol 26:783-90. 2010
    ..Also, variations in concentrations of antiepileptic drugs across the menstrual cycle may contribute to increased seizure susceptibility. A variety of approaches have been proposed for the treatment of catamenial epilepsy...
  23. ncbi request reprint Photosensitivity and epilepsy: a follow-up study
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti Ospedale Policlinico, Chieti, Italy
    Dev Med Child Neurol 46:347-51. 2004
    ..Thirty-three patients became seizure-free. Our study confirms that photosensitive epilepsy has a good prognosis for seizure control that is independent of the persistence or disappearance of photosensitivity...
  24. doi request reprint Nonalcoholic fatty liver disease during valproate therapy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, 5 66100, Chieti Italy
    Eur J Pediatr 168:1391-4. 2009
    ..The present case suggests that obesity, hyperinsulinemia, insulin resistance, and long-term treatment with VPA may be all associated with the development of NAFLD; this side effect is reversible after VPA withdrawal...
  25. ncbi request reprint Levetiracetam monotherapy for children and adolescents with benign rolandic seizures
    A Verrotti
    Department of Pediatrics, University of Chieti, Policlinico Universitario, Via dei Vestini 5, 66100 Chieti, Italy
    Seizure 16:271-5. 2007
    ..5%) patients. Our results support findings that LEV monotherapy is effective and well tolerated in children with BECTS. Prospective, large, long-term double-blind studies are needed to confirm these findings...
  26. ncbi request reprint Antiepileptic drugs and visual function
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Neurol 36:353-60. 2007
    ....
  27. ncbi request reprint Extended-release formulations in epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    J Child Neurol 22:419-26. 2007
    ..The results of these studies are encouraging and suggest a good tolerability and efficacy of these extended-release formulations, although larger studies are needed...
  28. ncbi request reprint Influence of sex hormones on brain excitability and epilepsy
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Endocrinol Invest 30:797-803. 2007
    ..This review provides an overview of the current knowledge in this field and highlights some of the prevailing hypotheses about the effects of sexual hormones on neuronal excitability analysing data from both animal and clinical studies...
  29. ncbi request reprint Color vision and macular recovery time in epileptic adolescents treated with valproate and carbamazepine
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Eur J Neurol 13:736-41. 2006
    ..Further investigations are required to determine the pathophysiological alteration(s) that are at the basis of color perception defects...
  30. ncbi request reprint The treatment of juvenile myoclonic epilepsy
    Alberto Verrotti
    University of Chieti, Alberto Verrotti Dept of Pediatrics, University of Chieti Ospedale Policlinico, Via dei Vestini 5, Italy
    Expert Rev Neurother 6:847-54. 2006
    ..Currently, administration of new antiepileptic drugs, such as levetiracetam, lamotrigine and topiramate, seems to have beneficial effects in the patients with poor response to valproate...
  31. doi request reprint Increased oxidative stress in epileptic children treated with valproic acid
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Epilepsy Res 78:171-7. 2008
    ..To determine influence of Valproic Acid (VPA) treatment on oxidative status in non-obese and overweight epileptic children...
  32. ncbi request reprint Adolescents and epilepsy: hormonal aspects
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Minerva Pediatr 60:417-28. 2008
    ..Changes in hormone serum levels that occur during pubertal period are probably related to modifications in seizure features and are involved in some types of epilepsy that begin typically in adolescence...
  33. ncbi request reprint Human photosensitivity: from pathophysiology to treatment
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Eur J Neurol 12:828-41. 2005
    ....
  34. ncbi request reprint Photosensitivity and epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 19:571-8. 2004
    ..Stimulus avoidance and stimulus modification can be an effective treatment in some patients and can sometimes be combined with antiepileptic drug treatment...
  35. doi request reprint Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Eur J Endocrinol 160:81-6. 2009
    ..This study evaluates the effects of long-term carbamazepine (CBZ) and valproate acid (VPA) therapy on thyroid function in epileptic children...
  36. doi request reprint Weight gain following treatment with valproic acid: pathogenetic mechanisms and clinical implications
    A Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Obes Rev 12:e32-43. 2011
    ....
  37. doi request reprint Antiepileptic drugs, sex hormones, and PCOS
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 52:199-211. 2011
    ..A better understanding of the effects of AEDs on sex hormones is key to selecting the appropriate AEDs and is crucial for reproductive health in female patients...
  38. doi request reprint Benign convulsions associated with mild gastroenteritis: a multicenter clinical study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Res 93:107-14. 2011
    ..To assess the clinical characteristics and the outcome of benign convulsions associated with mild gastroenteritis (CwG) in Italian children...
  39. ncbi request reprint Levetiracetam monotherapy for childhood occipital epilepsy of gastaut
    A Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Acta Neurol Scand 120:342-6. 2009
    ..The aim of this open label pilot study was to evaluate the efficacy and tolerability of levetiracetam (LEV) as 'de novo' monotherapy in children and adolescents with late onset childhood occipital epilepsy-Gastaut type (COE-G)...
  40. doi request reprint Topiramate-induced weight loss: a review
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66013 Chieti, Italy
    Epilepsy Res 95:189-99. 2011
    ..In international literature, the reported body weight loss incidences linked to TPM therapy vary widely and, in some cases, are very conflicting...
  41. doi request reprint Pharmacotherapy for children and adolescents with epilepsy
    Alberto Verrotti
    University of Chieti, Department of Pediatrics, Ospedale Policlinico, Via dei Vestini 5, Chieti, Italy
    Expert Opin Pharmacother 12:175-94. 2011
    ..Childhood epilepsies are the most frequent neurological problems that occur in children. Despite the introduction of new antiepileptic drugs (AEDs) 25-30% of children with epilepsy remain refractory to medical therapy...
  42. doi request reprint Cognitive and linguistic abnormalities in benign childhood epilepsy with centrotemporal spikes
    A Verrotti
    Department of Paediatrics, University of Chieti, Italy
    Acta Paediatr 100:768-72. 2011
    ..To assess the cognitive function and language ability in children with benign partial epilepsy with centrotemporal spikes...
  43. doi request reprint Afebrile benign convulsions with mild gastroenteritis: a new entity?
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Ospedale Policlinico, Chieti, Italy
    Acta Neurol Scand 120:73-9. 2009
    ..In conclusion, this type of seizure seems to be a new entity, but it awaits a correct place in the large group of infantile convulsion disorders...
  44. ncbi request reprint Update of the medical treatment of West syndrome
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Minerva Pediatr 59:249-53. 2007
    ..This review outlines the usefulness of the different antiepileptic drugs for the treatment of West syndrome...
  45. ncbi request reprint Effects of irbesartan on intracellular antioxidant enzyme expression and activity in adolescents and young adults with early diabetic angiopathy
    Francesco Chiarelli
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini, 5, I 66100 Chieti, Italy
    Diabetes Care 28:1690-7. 2005
    ..The objective of this study was to evaluate the effects of irbesartan, an angiotensin II receptor antagonist, on IAP in adolescents and young adults with type 1 diabetes and early signs of retinopathy and nephropathy...
  46. doi request reprint Long term outcome in children affected by absence epilepsy with onset before the age of three years
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 20:366-9. 2011
    ..The goal of this study was to define the long-term outcome of absence epilepsy presenting before the age of 3 years...
  47. ncbi request reprint Factors associated with poor control in partial complex epilepsy
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 19:262-4. 2004
    ....
  48. ncbi request reprint Insulin resistance in epileptic girls who gain weight after therapy with valproic acid
    Alberto Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    J Child Neurol 17:265-8. 2002
    ..Therefore, these obese patients could be exposed to the risks related to these metabolic abnormalities; if these data are confirmed in longer studies, these side effects may raise some concerns about the safety of valproic acid...
  49. doi request reprint Epilepsy in patients with Cornelia de Lange syndrome: a clinical series
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Seizure 22:356-9. 2013
    ..Epilepsy is a clinical feature found in about 20% of cases, but there are no data about its electroclinical features and long-term outcome...
  50. ncbi request reprint Levetiracetam in absence epilepsy
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Chieti, Italy
    Dev Med Child Neurol 50:850-3. 2008
    ..Prospective, large, long-term double-blind studies are needed to confirm these findings...
  51. doi request reprint The effect of recurrent severe hypoglycemia on cognitive performance in children with type 1 diabetes: a meta-analysis
    Annalisa Blasetti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 26:1383-91. 2011
    ..However, these results must be considered with caution taking into account factors such as small sample sizes, the different definitions of severe hypoglycemia, and the variety of neuropsychological tests used...
  52. ncbi request reprint Risk factors for recurrence of epilepsy and withdrawal of antiepileptic therapy: a practical approach
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti Ospedale Policlinico, Italy
    Ann Med 35:207-15. 2003
    ..In this review we analyse data from the literature and we suggest a practical approach for safe anticonvulsant withdrawal, although the decision should always be made individually, weighing risks and benefits...
  53. ncbi request reprint Increased vascular endothelial growth factor serum concentrations may help to identify patients with onset of type 1 diabetes during childhood at risk for developing persistent microalbuminuria
    F Santilli
    Department of Medicine, Division of Pediatrics, University of Chieti, 66100 Chieti, Italy
    J Clin Endocrinol Metab 86:3871-6. 2001
    ..Persistently increased vascular endothelial growth factor serum levels may help to identify normotensive, normoalbuminuric patients with type 1 diabetes who are predisposed to develop persistent microalbuminuria later in life...
  54. doi request reprint Long-term outcome of epilepsy in Kabuki syndrome
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100 Chieti, Italy
    Seizure 20:650-4. 2011
    ..Therefore, we describe here a clinical series of 10 Caucasian KS patients who developed epilepsy in childhood. We followed all children for at least 5 years...
  55. ncbi request reprint Peri-ictal and inter-ictal headache in children and adolescents with idiopathic epilepsy: a multicenter cross-sectional study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Childs Nerv Syst 27:1419-23. 2011
    ..Headache in epileptic population ranges from 8% to 15%. The aim of this paper was to study the clinical and temporal characteristics of primary headache comorbidity in idiopathic epileptic children...
  56. doi request reprint Nonalcoholic fatty liver disease in adolescents receiving valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 20:382-5. 2011
    ..The aim of this study was to investigate the association between the metabolic derangements induced by valproic acid (VPA) and ultrasound-diagnosed nonalcoholic fatty liver disease (NAFLD) in adolescents...
  57. doi request reprint Valproate-induced insulin resistance and obesity in children
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Horm Res 71:125-31. 2009
    ..Among the side effects of VPA, weight gain is frequently reported, although the real incidence and magnitude of this problem is unknown. Its pathogenesis is most likely multifactorial, and is controversial...
  58. ncbi request reprint Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Neuroendocrinology 79:157-62. 2004
    ..In conclusion, the data suggest that epileptic patients who gain weight after VPA therapy have reduced plasma concentrations of antioxidant vitamins and that these reductions are reversible after VPA withdrawal...
  59. doi request reprint Levetiracetam in juvenile myoclonic epilepsy: long-term efficacy in newly diagnosed adolescents
    Alberto Verrotti
    Department of Paediatrics, University of Chieti, Rome, Italy
    Dev Med Child Neurol 50:29-32. 2008
    ..At 12-month evaluation: 29 patients were seizure free; three patients were responders. No patients reported adverse events. These data provide preliminary evidence that LEV may be effective for treating patients with newly diagnosed JME...
  60. doi request reprint Could receptors for advanced glycation end products be considered cardiovascular risk markers in obese children?
    Tommaso de Giorgis
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Antioxid Redox Signal 17:187-91. 2012
    ..Our findings lead to the hypothesis that RAGE system seems to be related to the development of atherosclerosis even in obese prepubertal children...
  61. doi request reprint Should "migralepsy" be considered an obsolete concept? A multicenter retrospective clinical/EEG study and review of the literature
    Alberto Verrotti
    Child Neurology and Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsy Behav 21:52-9. 2011
    ....
  62. doi request reprint Electroclinical features and long-term outcome of cryptogenic epilepsy in children with Down syndrome
    Alberto Verrotti
    Department of Pediatrics, University of Perugia, Perugia, Italy
    J Pediatr 163:1754-8. 2013
    ..To describe the electroclinical features and the long-term outcomes of epilepsy in a large cohort of males and females with Down syndrome who developed epilepsy in childhood...
  63. doi request reprint Clinical dissection of early onset absence epilepsy in children and prognostic implications
    Sergio Agostinelli
    Child Epilepsy Center, Department of Pediatrics, University of Chieti, Chieti, Italy
    Epilepsia 54:1761-70. 2013
    ....
  64. ncbi request reprint Seizures and epilepsy in Sotos syndrome: analysis of 19 Caucasian patients with long-term follow-up
    Francesco Nicita
    Child Neurology Division, Department of Pediatrics, Policlinico Umberto I, Sapienza University of Rome, Roma, Italy
    Epilepsia 53:e102-5. 2012
    ..Seizures were easy to control with common antiepileptic drugs in almost all patients. A careful neurologic evaluation is useful for SS patients, since seizures are an important finding among people with this overgrowth syndrome...
  65. doi request reprint The possible role of esRAGE and sRAGE in the natural history of diabetic nephropathy in childhood
    Cosimo Giannini
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, 66100, Chieti, Italy
    Pediatr Nephrol 27:269-75. 2012
    ..The inverse association between esRAGE levels and early kidney alterations suggests a potential role of esRAGE in diabetic nephropathy...
  66. ncbi request reprint von Willebrand factor and its propeptide in children with diabetes. Relation between endothelial dysfunction and microalbuminuria
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Oespedale Policlinico, Chieti, Italy
    Pediatr Res 53:382-6. 2003
    ....
  67. doi request reprint Developmental anomalies of the medial septal area: possible implication for limbic epileptogenesis
    Paola Iannetti
    Department of Pediatrics, Child Neurology Division, Sapienza University, La Sapienza Roma, Viale Regina Elena 324, 00161, Rome, Italy
    Childs Nerv Syst 27:765-70. 2011
    ..The limbic system includes a group of interconnected gray and white matter structures; in this circuit, the fornix is an important white matter connection with the septum pellucidum...
  68. doi request reprint Weight gain and insulin resistance in children treated with valproate: the influence of time
    Fabio Masuccio
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Child Neurol 25:941-7. 2010
    ..These results might be helpful to enhance the knowledge of valproic acid action on both insulin resistance and weight gain, allowing to plan appropriate approach for the prevention of the consequences of the treatment with valproic acid...
  69. ncbi request reprint Antiepileptic drugs and thyroid function
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    J Pediatr Endocrinol Metab 21:401-8. 2008
    ..The aim of this review is to analyse critically the principal alterations in thyroid function caused by AED therapy...
  70. ncbi request reprint Typical and atypical rolandic epilepsy in childhood: a follow-up study
    Alberto Verrotti
    Department of Pediatrics Policlinico Colle Dell Ara, University of Chieti, Via dei Vestini 5, I 66013 Chieti, Italy
    Pediatr Neurol 26:26-9. 2002
    ..5% vs 7.8%; P < 0.0001). In conclusion, atypical rolandic epilepsy seems to be associated with a high percentage of learning and behavioral disorders...
  71. doi request reprint Diffuse onset of ictal electroencephalography in a typical case of Panayiotopoulos syndrome and review of the literature
    Paola Iannetti
    Department of Pediatrics, Division of Child Neurology, La Sapienza University of Rome, Viale Regina Elena 324, Rome, Italy
    J Child Neurol 24:472-6. 2009
    ....
  72. doi request reprint Hormonal and reproductive disturbances in epileptic male patients: emerging issues
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Reprod Toxicol 31:519-27. 2011
    ..To review the relationship between epilepsy, antiepileptic drugs and reproductive function...
  73. doi request reprint What is the significance of soluble and endogenous secretory receptor for advanced glycation end products in liver steatosis in obese prepubertal children?
    Ebe D'Adamo
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Antioxid Redox Signal 14:1167-72. 2011
    ..These findings suggest that AGE-RAGE pathway plays an independent role in the development of liver injury already present in this age group...
  74. doi request reprint Obese children suffer more often from migraine
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Acta Paediatr 101:e416-21. 2012
    ..To determine a possible relationship between migraine and body mass index...
  75. ncbi request reprint Increased bone turnover in prepubertal, pubertal, and postpubertal patients receiving carbamazepine
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Epilepsia 43:1488-92. 2002
    ..To study the markers of bone turnover in epilepsy patients in the different stages of the pubertal growth before and after the beginning of carbamazepine (CBZ) monotherapy...
  76. doi request reprint Variables associated with severe hypoglycemia in children and adolescents with type 1 diabetes: a population-based study
    Annalisa Blasetti
    Department of Pediatrics, University of Chieti, Via dei Vestini 5, Chieti, Italy
    Pediatr Diabetes 12:4-10. 2011
    ..The aim of our study was to determine the incidence of SH and associated variables in a population of children and adolescents with T1DM...
  77. doi request reprint Early-onset pure absence epilepsy: a distinct epileptic syndrome
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Acta Paediatr 100:647-50. 2011
    ..This review summarizes the current understanding on this epilepsy...
  78. ncbi request reprint Benign focal epilepsy with onset in infancy in a patient with 18q-syndrome
    Alberto Verrotti
    Section of Pediatrics, Department of Medicine, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Childs Nerv Syst 20:362-5. 2004
    ..The EEGs performed during sleep showed low-voltage spikes over the fronto-central region of the left hemisphere. The magnetic resonance imaging of the brain was normal...
  79. ncbi request reprint Diabetic neuropathy in children and adolescents
    Daniela Trotta
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Diabetes 5:44-57. 2004
    ..Etiopathogenetic theories and diagnostic tools are also reviewed from in a pediatric perspective...
  80. ncbi request reprint Old and new antiepileptic drugs for the treatment of idiopathic generalized epilepsies
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66013 Chieti, Italy
    Curr Clin Pharmacol 2:249-59. 2007
    ..Today, "new" antiepileptic drugs, such as lamotrigine, levetiracetam, topiramate and zonisamide are useful tools in the treatment of pharmacoresistant epilepsies...
  81. ncbi request reprint Endocrine and metabolic changes in epileptic patients receiving valproic acid
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    J Pediatr Endocrinol Metab 18:423-30. 2005
    ....
  82. ncbi request reprint Preventing microvascular diabetic complications in children and adolescents: looking beyond glycaemic control
    Alberto Verrotti
    Department of Pediatrics Policlinico Colle Dell Ara, University G D Annunzio, Via dei Vestini 5, I 66013 Chieti, Italy
    Expert Opin Pharmacother 4:525-32. 2003
    ..Therapeutic interventions, particularly excellent metabolic control, may be almost effective in preventing complication onset, or significantly retarding the rate of progression...
  83. ncbi request reprint Recent advances on neural tube defects with special reference to Valproic Acid
    Alberto Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Italy
    Endocr Metab Immune Disord Drug Targets 6:25-31. 2006
    ..There is strong evidence for a protective effect of adequate folate consumption...
  84. ncbi request reprint Effects of vitamin E supplementation on intracellular antioxidant enzyme production in adolescents with type 1 diabetes and early microangiopathy
    Francesco Chiarelli
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini, 5, I 66100 Chieti, Italy
    Pediatr Res 56:720-5. 2004
    ..Adolescents with early signs of diabetic angiopathy have defective IAP and activity, which are not modified by vitamin E...
  85. ncbi request reprint Leptin, ghrelin, and adiponectin in epileptic patients treated with valproic acid
    R Greco
    Department of Medicine, University of Chieti, Italy
    Neurology 65:1808-9. 2005
    ..5%) had development of obesity. They showed circulating leptin and insulin levels significantly higher and ghrelin and adiponectin levels significantly lower than those of patients who did not gain weight...
  86. ncbi request reprint Retinal nerve fiber layer and macular thickness in adolescents with epilepsy treated with valproate and carbamazepine
    Lucio Lobefalo
    Department of Experimental Surgery, Section of Ophthalmology, University of Chieti, Italy
    Epilepsia 47:717-9. 2006
    ..To evaluate retinal nerve retinal nerve fiber layer (RNFL) and macular thickness by using optical coherence tomography (OCT) in epileptic adolescents before and during monotherapy with valproic acid (VPA) and carbamazepine (CBZ)...
  87. ncbi request reprint Valproate-induced hyperammonemic encephalopathy
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Metab Brain Dis 17:367-73. 2002
    ..Moreover, VHE seems to be more frequently in patients with carnitine deficiency or with congenital urea cycle enzymatic defects...
  88. ncbi request reprint Thyroid hormones in epileptic children receiving carbamazepine and valproic acid
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Chieti, Italy
    Pediatr Neurol 25:43-6. 2001
    ..Thyroid-stimulating hormone and thyrotropin-releasing hormone levels do not seem to be affected by these drugs, suggesting that hypothalamic function is not affected in these children...
  89. ncbi request reprint New trends in the treatment of diabetic nephropathy in children
    Alberto Verrotti
    Department of Pediatrics, Ospedale Policlinico, Via dei Vestini, Chieti, Italy
    Expert Opin Pharmacother 3:1169-76. 2002
    ..In this review controversial aspects of this issue are presented and discussed...
  90. doi request reprint Increased concentrations of soluble CD40 ligand may help to identify type 1 diabetic adolescents and young adults at risk for developing persistent microalbuminuria
    F Chiarelli
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Diabetes Metab Res Rev 24:570-6. 2008
    ..Soluble CD40 ligand (sCD40L) is supposed to be one of the most likely candidates for both retinopathy and nephropathy...
  91. ncbi request reprint Photoparoxysmal responses in non-epileptic children in long-term follow-up
    A Verrotti
    Department of Medicine, Division of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Acta Neurol Scand 105:400-2. 2002
    ..To evaluate the photoparoxysmal responses (PPR) in non-epileptic children and adolescents in long-term follow-up...
  92. ncbi request reprint New trends in the etiopathogenesis of diabetic peripheral neuropathy
    A Verrotti
    Department of Medicine, University of Chieti, Italy
    J Child Neurol 16:389-94. 2001
    ..The role of other factors, such as possible direct neurotrophic effects of insulin and insulin-related growth factors, seems to be relevant...
  93. ncbi request reprint Anticardiolipin, glutamic acid decarboxylase, and antinuclear antibodies in epileptic patients
    A Verrotti
    Department of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, I 66013 Chieti, Italy
    Clin Exp Med 3:32-6. 2003
    ..There was no significant difference in serum glutamic acid decarboxylase antibodies between epileptic children and controls, and between patients who were seizure free and those with uncontrolled epilepsy...
  94. ncbi request reprint Febrile convulsions after 5 years of age: long-term follow-up
    A Verrotti
    Department of Medicine, University of Chieti, Italy
    J Child Neurol 15:811-3. 2000
    ..1% vs 7.4%, P < .05). Our data suggest that children with febrile convulsions after 5 years of age probably must be considered as a group of patients at risk of developing unprovoked seizures...
  95. ncbi request reprint Discontinuation of anticonvulsant therapy in children with partial epilepsy
    A Verrotti
    Department of Medicine, University of Chieti, Ospedale Policlinico, Italy
    Neurology 55:1393-5. 2000
    ..8%; Group B, 25%). It is safe to discontinue the anticonvulsant therapy in children with cryptogenic partial epilepsy who were seizure free for only 1 year...
  96. ncbi request reprint Vascular endothelial growth factor (VEGF) in children, adolescents and young adults with Type 1 diabetes mellitus: relation to glycaemic control and microvascular complications
    F Chiarelli
    Department of Medicine, University of Chieti, Italy
    Diabet Med 17:650-6. 2000
    ....
  97. ncbi request reprint Epilepsy and adolescents
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Ospedale Policlinico, Via dei Vestini 5, 66100 Chieti, Italy
    Panminerva Med 45:231-40. 2003
    ..Some study report that the children treated with CBZ may have subclinical signs of hypothyroidism, and these changes are more evident if CBZ is given in association with another drug for example with VPA...
  98. ncbi request reprint Color vision in epileptic adolescents treated with valproate and carbamazepine
    A Verrotti
    Division of Pediatric, Department of Medicine, Ospedale Policlinico, Via dei Vestini 5, I 66100 Chieti, Italy
    Seizure 13:411-7. 2004
    ....
  99. ncbi request reprint Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine
    A Verrotti
    Department of Medicine, Section of Pediatrics, University of Chieti, Via dei Vestini 5, I 66100, Chieti, Italy
    Epilepsy Res 41:253-7. 2000
    ....
  100. ncbi request reprint Serum leptin changes during weight loss in obese diabetic subjects with and without microalbuminuria
    A Verrotti
    Department of Medicine, University of Chieti, Italy
    Diabetes Nutr Metab 14:283-7. 2001
    ..The changes of leptin in diabetics seem to be similar to those observed in healthy obese subjects...
  101. ncbi request reprint Magnetoencephalographic and electroencephalographic evaluation in patients with cryptogenetic partial epilepsy
    A Verrotti
    Department of Pediatrics, University of Chieti, Chieti, Italy
    Neurophysiol Clin 33:174-9. 2003
    ..Magnetoencephalography (MEG) has been applied for more than 20 years to the localization of the epileptic focus in partial epilepsies, but correlation with electroencephalographic (EEG) data in homogeneous groups of patients is scarce...