Affiliation: University of Milan
Verderio C, Gabrielli M, Giussani P. Role of sphingolipids in the biogenesis and biological activity of extracellular vesicles. J Lipid Res. 2018;59:1325-1340 pubmed publisher
..Last, we look ahead at some biological effects of EVs mediated by changes in SL levels in recipient cells. ..
Verderio C, Muzio L, Turola E, Bergami A, Novellino L, Ruffini F, et al
. Myeloid microvesicles are a marker and therapeutic target for neuroinflammation. Ann Neurol. 2012;72:610-24 pubmed publisher
..Finally, FTY720, the first approved oral MS drug, significantly reduced the amount of MVs in the CSF of EAE-treated mice. These findings identify myeloid MVs as a marker and therapeutic target of brain inflammation. ..
Joshi P, Benussi L, Furlan R, Ghidoni R, Verderio C. Extracellular vesicles in Alzheimer's disease: friends or foes? Focus on aÎ²-vesicle interaction. Int J Mol Sci. 2015;16:4800-13 pubmed publisher
..In this review we focus on studies which investigated the impact of EVs in AÎ²-mediated neurodegeneration and showed either detrimental or protective role for EVs in the pathology. ..
Morini R, Ghirardini E, Butti E, Verderio C, Martino G, Matteoli M. Subventricular zone neural progenitors reverse TNF-alpha effects in cortical neurons. Stem Cell Res Ther. 2015;6:166 pubmed publisher
Riganti L, Antonucci F, Gabrielli M, Prada I, Giussani P, Viani P, et al
. Sphingosine-1-Phosphate (S1P) Impacts Presynaptic Functions by Regulating Synapsin I Localization in the Presynaptic Compartment. J Neurosci. 2016;36:4624-34 pubmed publisher
Verderio C, Bianco F, Blanchard M, Bergami M, Canossa M, Scarfone E, et al
. Cross talk between vestibular neurons and Schwann cells mediates BDNF release and neuronal regeneration. Brain Cell Biol. 2006;35:187-201 pubmed
..Given the massive release of ATP during tissue damage, cross-talk between vestibular neurons and Schwann cells could play a primary role during regeneration. ..
Verderio C, Cagnoli C, Bergami M, Francolini M, Schenk U, Colombo A, et al
. TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes. Biol Cell. 2012;104:213-28 pubmed publisher
Prada I, Gabrielli M, Turola E, Iorio A, D Arrigo G, Parolisi R, et al
. Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations. Acta Neuropathol. 2018;135:529-550 pubmed publisher