Paolo Vercellini

Summary

Affiliation: University of Milan
Country: Italy

Publications

  1. ncbi Adenomyosis: epidemiological factors
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, University of Milan, and the Centre for Research in Obstetrics and Gynaecology, Milan, Italy
    Best Pract Res Clin Obstet Gynaecol 20:465-77. 2006
  2. ncbi Surgery for endometriosis-associated infertility: a pragmatic approach
    Paolo Vercellini
    Gynaecologic Surgery Division, Department of Obstetrics and Gynaecology, University of Milan, Via Commenda 12, 20122 Milano, Italy
    Hum Reprod 24:254-69. 2009
  3. ncbi Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. Effect on pain during intercourse and patient satisfaction
    P Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Università Statale di Milano, 20122 Milan, Italy
    Hum Reprod 27:3450-9. 2012
  4. ncbi Long-term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta-analysis
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Acta Obstet Gynecol Scand 92:8-16. 2013
  5. ncbi Attractiveness of women with rectovaginal endometriosis: a case-control study
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Universita degli Studi, and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Fertil Steril 99:212-8. 2013
  6. ncbi "I can't get no satisfaction": deep dyspareunia and sexual functioning in women with rectovaginal endometriosis
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Università Statale di Milano, Milan, Italy
    Fertil Steril 98:1503-11.e1. 2012
  7. ncbi Effect of patient selection on estimate of reproductive success after surgery for rectovaginal endometriosis: literature review
    Paolo Vercellini
    Department of Obstetrics and Gynecology, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Reprod Biomed Online 24:389-95. 2012
  8. ncbi Postoperative oral contraceptive exposure and risk of endometrioma recurrence
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan, Milan, Italy
    Am J Obstet Gynecol 198:504.e1-5. 2008
  9. ncbi Endometriosis: current and future medical therapies
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica II, University of Milan, Istituto Luigi Mangiagalli, Via Commenda, Milan, Italy
    Best Pract Res Clin Obstet Gynaecol 22:275-306. 2008
  10. ncbi Asymmetry in distribution of diaphragmatic endometriotic lesions: evidence in favour of the menstrual reflux theory
    P Vercellini
    Department of Obstetrics and Gynaecology, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Hum Reprod 22:2359-67. 2007

Detail Information

Publications88

  1. ncbi Adenomyosis: epidemiological factors
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, University of Milan, and the Centre for Research in Obstetrics and Gynaecology, Milan, Italy
    Best Pract Res Clin Obstet Gynaecol 20:465-77. 2006
    ....
  2. ncbi Surgery for endometriosis-associated infertility: a pragmatic approach
    Paolo Vercellini
    Gynaecologic Surgery Division, Department of Obstetrics and Gynaecology, University of Milan, Via Commenda 12, 20122 Milano, Italy
    Hum Reprod 24:254-69. 2009
    ..Complete and detailed information on risks and benefits of treatment alternatives must be offered to infertile patients to allow unbiased choices between possible options...
  3. ncbi Surgical versus medical treatment for endometriosis-associated severe deep dyspareunia: I. Effect on pain during intercourse and patient satisfaction
    P Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Università Statale di Milano, 20122 Milan, Italy
    Hum Reprod 27:3450-9. 2012
    ..STUDY FUNDING/COMPETING INTEREST(S): This study was supported by a research grant from the University of Milan School of Medicine (PUR number 2009-ATE-0570). None of the authors have a conflict of interest...
  4. ncbi Long-term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta-analysis
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Acta Obstet Gynecol Scand 92:8-16. 2013
    ..11-0.40) and 0.39 (95% confidence interval 0.23-0.66). Postoperative OC use dramatically decreased the risk of ovarian endometrioma recurrence, especially in women who used OCs regularly and for prolonged periods...
  5. ncbi Attractiveness of women with rectovaginal endometriosis: a case-control study
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Universita degli Studi, and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Fertil Steril 99:212-8. 2013
    ..To evaluate physical attractiveness in women with and without endometriosis...
  6. ncbi "I can't get no satisfaction": deep dyspareunia and sexual functioning in women with rectovaginal endometriosis
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Università Statale di Milano, Milan, Italy
    Fertil Steril 98:1503-11.e1. 2012
    ..To assess the impact of rectovaginal endometriosis on pain at intercourse and sexual functioning...
  7. ncbi Effect of patient selection on estimate of reproductive success after surgery for rectovaginal endometriosis: literature review
    Paolo Vercellini
    Department of Obstetrics and Gynecology, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Reprod Biomed Online 24:389-95. 2012
    ..The 15% difference is statistically significant. Infertile patients with rectovaginal endometriosis considering surgery, should be carefully informed of the real probability of post-operative conception avoiding generic overestimations...
  8. ncbi Postoperative oral contraceptive exposure and risk of endometrioma recurrence
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan, Milan, Italy
    Am J Obstet Gynecol 198:504.e1-5. 2008
    ..The purpose of this study was to compare the postoperative risk of endometrioma recurrence in women using oral contraception and in those undergoing simple observation...
  9. ncbi Endometriosis: current and future medical therapies
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica II, University of Milan, Istituto Luigi Mangiagalli, Via Commenda, Milan, Italy
    Best Pract Res Clin Obstet Gynaecol 22:275-306. 2008
    ..Medical treatment is not indicated in women seeking conception because reproductive prognosis is not ameliorated...
  10. ncbi Asymmetry in distribution of diaphragmatic endometriotic lesions: evidence in favour of the menstrual reflux theory
    P Vercellini
    Department of Obstetrics and Gynaecology, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Hum Reprod 22:2359-67. 2007
    ....
  11. ncbi Post-operative endometriosis recurrence: a plea for prevention based on pathogenetic, epidemiological and clinical evidence
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, University of Milan and Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Reprod Biomed Online 21:259-65. 2010
    ..16 (95% CI 0.04-0.65). After first-line surgery for endometriosis, women should be invited to seek conception as soon as possible. Alternatively, oral contraceptive use until pregnancy is desired should be considered...
  12. ncbi Asymmetric lateral distribution of obstructed hemivagina and renal agenesis in women with uterus didelphys: institutional case series and a systematic literature review
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan, Milan, Italy
    Fertil Steril 87:719-24. 2007
    ..To investigate if an asymmetry exists in the lateral distribution of obstructed hemivagina and renal agenesis in women with uterus didelphys...
  13. ncbi The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review
    Paolo Vercellini
    Department of Obstetrics and Gynecology, University of Milan, Milan, Italy
    Acta Obstet Gynecol Scand 88:1074-82. 2009
    ..58-3.91%). Conclusions. The probability of conception after repeat surgery for recurrent endometriosis appeared limited and reduced compared with that after primary surgery. The results of IVF were not inferior to those of reoperation...
  14. ncbi Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, Università Statale di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda 12, Milan, Italy
    Hum Reprod Update 17:159-70. 2011
    ..The aim of this review is to establish if OC use influences the risk of endometriosis...
  15. ncbi The second time around: reproductive performance after repetitive versus primary surgery for endometriosis
    Paolo Vercellini
    Division of Gynecologic Surgery, Istituto Ostetrico e Ginecologico Luigi Mangiagalli, Universita degli Studi di Milano, Milan, Italy
    Fertil Steril 92:1253-5. 2009
    ..55; 95% confidence interval, 0.30 to 0.99), and the 12- and 24-month cumulative pregnancy rates were 13% and 22% in the former group and 25% and 30% in the latter...
  16. ncbi Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: a multivariate analysis of over 1000 patients
    P Vercellini
    First Department of Obstetrics and Gynaecology, University of Milano, Italy
    Hum Reprod 22:266-71. 2007
    ....
  17. ncbi Reproductive performance, pain recurrence and disease relapse after conservative surgical treatment for endometriosis: the predictive value of the current classification system
    Paolo Vercellini
    First Department of Obstetrics and Gynaecology, University of Milano, Italy
    Hum Reprod 21:2679-85. 2006
    ....
  18. ncbi The effect of surgery for symptomatic endometriosis: the other side of the story
    P Vercellini
    Department of Obstetrics and Gynecology, University of Milan, Italy
    Hum Reprod Update 15:177-88. 2009
    ..Surgery is often considered the best treatment option in women with symptomatic endometriosis. However, extent and duration of the therapeutic benefit are still poorly defined...
  19. ncbi Medical treatment for rectovaginal endometriosis: what is the evidence?
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, Istituto Luigi Mangiagalli, University of Milan, Via Commenda 12, 20122 Milan, Italy
    Hum Reprod 24:2504-14. 2009
    ..Surgical treatment may be effective but is associated with a high risk of morbidity and major complications. Information on the effect of medical alternatives for pain relief in this condition is scarce...
  20. ncbi Levonorgestrel-releasing intrauterine system for the treatment of endometriosis: biological and clinical evidence
    Paola Vigano
    University of Milan, Department of Obstetrics, Gynecology and Neonatology, Fondazione Ospedale Policlinico Mangiagalli Regina Elena, Center for Research in Obstetrics and Gynecology, Milano, Via Commenda 12, 20122 Milan, Italy
    Womens Health (Lond Engl) 3:207-14. 2007
    ..Thus, the intrauterine delivery of a potent progestin may constitute an innovative, effective, safe and convenient alternative for local delivery of a potent progestin in the long-term therapy of symptomatic endometriosis...
  21. ncbi Repetitive surgery for recurrent symptomatic endometriosis: what to do?
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, University of Milan, Istituto Luigi Mangiagalli, Via Commenda 12 20122 Milan, Italy
    Eur J Obstet Gynecol Reprod Biol 146:15-21. 2009
    ..Studies on surgical management of recurrent rectovaginal endometriosis are warranted, due to the peculiar technical difficulties as well as the high risk of complications associated with this challenging disease form...
  22. ncbi Surgery for deep endometriosis: a pathogenesis-oriented approach
    Paolo Vercellini
    Department of Obstetrics and Gynecology, Istituto Luigi Mangiagalli, University of Milan, IT 20122 Milan, Italy
    Gynecol Obstet Invest 68:88-103. 2009
    ..Deep endometriosis is usually associated with severe symptoms and constitutes a complex treatment challenge...
  23. ncbi Gynecological endoscopy for symptomatic endometriosis
    P Vercellini
    Department of Obstetrics and Gynecology University of Milan, Milan 20122, Italy
    Minerva Ginecol 61:215-26. 2009
    ..Clinicians and patients should be aware that the expected benefit is operator-dependent and, especially in complex conditions, acceptable results can be assured in referral centers...
  24. ncbi Endometriosis: current therapies and new pharmacological developments
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, University of Milan, Milan, Italy
    Drugs 69:649-75. 2009
    ..Finally, as reproductive prognosis is not ameliorated by medical treatment, it is not indicated for women seeking conception...
  25. ncbi Chronic pelvic pain in women: etiology, pathogenesis and diagnostic approach
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, University of Milan, Milan, Italy
    Gynecol Endocrinol 25:149-58. 2009
    ..CPP is a symptom, not a disease, and rarely reflects a single pathologic process. Gaining women's trust and developing a strong patient-physician relationship is of utmost importance for the long-term outcome of care...
  26. ncbi Comparison of contraceptive ring and patch for the treatment of symptomatic endometriosis
    Paolo Vercellini
    Istituto Ostetrico e Ginecologico Luigi Mangiagalli, Universita degli Studi di Milano, 20122 Milan, Italy
    Fertil Steril 93:2150-61. 2010
    ..To evaluate the efficacy and tolerability of a contraceptive vaginal ring and transdermal patch in the treatment of endometriosis-associated pain...
  27. ncbi Medical, surgical and alternative treatments for chronic pelvic pain in women: a descriptive review
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, University of Milan, Milan, Italy
    Gynecol Endocrinol 25:208-21. 2009
    ..A minority of patients (3-5%) will experience worsening of pain or will develop new symptoms after surgery. Treatment of CPP, generally, requires acceptance of the concept of managing rather than curing symptoms...
  28. ncbi Treatment of symptomatic rectovaginal endometriosis with an estrogen-progestogen combination versus low-dose norethindrone acetate
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, University of Milan, Istituto Luigi Mangiagalli, Milan, Italy
    Fertil Steril 84:1375-87. 2005
    ..To evaluate the efficacy, safety, and tolerability of an estrogen-progestogen combination versus low-dose norethindrone acetate in the treatment of persistent pain after surgery for symptomatic rectovaginal endometriosis...
  29. ncbi Cyproterone acetate versus a continuous monophasic oral contraceptive in the treatment of recurrent pelvic pain after conservative surgery for symptomatic endometriosis
    Paolo Vercellini
    Istituto Ostetrico e Ginecologico Luigi Mangiagalli, University of Milan, Milan, Italy
    Fertil Steril 77:52-61. 2002
    ..To evaluate the efficacy and safety of cyproterone acetate versus an oral contraceptive in the treatment of endometriosis-associated recurrent pelvic pain...
  30. ncbi Endometriosis: preoperative and postoperative medical treatment
    Paolo Vercellini
    Luigi Mangiagalli Department of Obstetrics and Gynecology, University of Milano, Via Commenda, 12 20122 Milano, Italy
    Obstet Gynecol Clin North Am 30:163-80. 2003
    ....
  31. ncbi Evidence for asymmetric distribution of sciatic nerve endometriosis
    Paolo Vercellini
    First Department of Obstetrics and Gynecology, University of Milano, Milan, Italy
    Obstet Gynecol 102:383-7. 2003
    ..To investigate if a lateral asymmetry exists in the distribution of endometriotic lesions of the sciatic nerve...
  32. ncbi The pathogenesis of bladder detrusor endometriosis
    Paolo Vercellini
    First Department of Obstetrics and Gynecology, University of Milano, Italy
    Am J Obstet Gynecol 187:538-42. 2002
    ....
  33. ncbi The 'incessant menstruation' hypothesis: a mechanistic ovarian cancer model with implications for prevention
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Università Statale di Milano, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Commenda, 12, 20122 Milan, Italy
    Hum Reprod 26:2262-73. 2011
    ..The use of oral contraceptives should be favoured for prolonged periods of time, especially in women with endometriosis, a population at doubled risk of gonadal malignancy...
  34. ncbi Laparoscopic uterosacral ligament resection for dysmenorrhea associated with endometriosis: results of a randomized, controlled trial
    Paolo Vercellini
    Reproductive Surgery Unit, First Department of Obstetrics and Gynecology, University of Milan, Milan, Italy
    Fertil Steril 80:310-9. 2003
    ..To evaluate the efficacy of laparoscopic resection of the uterosacral ligaments in women with endometriosis and predominantly midline dysmenorrhea...
  35. ncbi Progestogens for endometriosis: forward to the past
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, Universita di Milano, Milano, Italy
    Hum Reprod Update 9:387-96. 2003
    ..However, their contraceptive effectiveness limits their use to women who do not wish to have children in the short term...
  36. ncbi Coagulation or excision of ovarian endometriomas?
    Paolo Vercellini
    First Department of Obstetrics and Gynecology, University of Milano, Italy
    Am J Obstet Gynecol 188:606-10. 2003
    ..The common odds ratio was 3.09 (95% CI 1.78-5.36). Coagulation or laser vaporization of endometriomas without excision of the pseudocapsule seems to be associated with a significant increase in risk of cyst recurrence...
  37. ncbi 'Blood On The Tracks' from corpora lutea to endometriomas
    P Vercellini
    Universita degli Studi di Milano, Milan, Italy
    BJOG 116:366-71. 2009
    ..To detect a direct transition from a haemorrhagic corpus luteum to an endometriotic cyst by serial transvaginal ultrasonographic scans...
  38. ncbi The role of the levonorgestrel-releasing intrauterine device in the management of symptomatic endometriosis
    Paolo Vercellini
    Obstetrics and Gynecology Clinic, Luigi Mangiagalli Institute, University of Milan, Milan, Italy
    Curr Opin Obstet Gynecol 17:359-65. 2005
    ..The aim of this article is to evaluate the biological rationale for the use of an intrauterine device releasing 20 mug/day of levonorgestrel in women with endometriosis, and to assess its efficacy in relieving pelvic pain symptoms...
  39. ncbi Priorities for endometriosis research: a proposed focus on deep dyspareunia
    Paolo Vercellini
    Istituto Ostetrico e Ginecologico Luigi Mangiagalli, Universita degli Studi di Milano, Milan, Italy
    Reprod Sci 18:114-8. 2011
    ..Time has come to address this physically and psychologically distressing affliction without embarrassment and with a decidedly multidisciplinary perspective...
  40. ncbi 'Waiting for Godot': a commonsense approach to the medical treatment of endometriosis
    Paolo Vercellini
    Department of Obstetrics and Gynaecology, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Hum Reprod 26:3-13. 2011
    ....
  41. ncbi Reproductive performance in infertile women with rectovaginal endometriosis: is surgery worthwhile?
    Paolo Vercellini
    Benign Gynecologic Surgery Unit, Clinica Ostetrica e Ginecologica II, University of Milan, Istituto Luigi Mangiagalli, Milan, Italy
    Am J Obstet Gynecol 195:1303-10. 2006
    ....
  42. ncbi Comparison of a levonorgestrel-releasing intrauterine device versus expectant management after conservative surgery for symptomatic endometriosis: a pilot study
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, University of Milano, Milan, Italy
    Fertil Steril 80:305-9. 2003
    ....
  43. ncbi Deep endometriosis: definition, pathogenesis, and clinical management
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    J Am Assoc Gynecol Laparosc 11:153-61. 2004
    ..Great importance must be given to complete and balanced counseling, as awareness of the real possibilities of different treatments will enhance the patient's collaboration...
  44. ncbi Continuous use of an oral contraceptive for endometriosis-associated recurrent dysmenorrhea that does not respond to a cyclic pill regimen
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, University of Milano, Milan, Italy
    Fertil Steril 80:560-3. 2003
    ..To ascertain whether long-term reduction of pain is obtained by continuous administration of an oral contraceptive (OC) in women with endometriosis-associated recurrent dysmenorrhea that does not respond to cyclic OC use...
  45. ncbi Treatment of endometriosis-related pain: options and outcomes
    Edgardo Somigliana
    Department of Obstetrics and Gynecology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Front Biosci (Elite Ed) 1:455-65. 2009
    ....
  46. ncbi Effect of delaying post-operative conception after conservative surgery for endometriosis
    Edgardo Somigliana
    Department of Obstetrics and Gynecology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Reprod Biomed Online 20:410-5. 2010
    ..However, these differences did not reach statistical significance and this advice is thus not mandatory. Larger studies are warranted to validate these conclusions...
  47. ncbi Fibroids not encroaching the endometrial cavity and IVF success rate: a prospective study
    Edgardo Somigliana
    Department of Obset Gynecol Fondazione Cà Granda, Ospedale Maggiore Policlinico, Via Commenda 12, 20122 Milano, Italy
    Hum Reprod 26:834-9. 2011
    ..CONCLUSIONS In asymptomatic patients selected for IVF, small fibroids not encroaching the endometrial cavity did not impact on the rate of success of the procedure...
  48. ncbi Pelvic endometriosis and hydroureteronephrosis
    Luca Carmignani
    Department of Medicine and Surgery, IRCCS Policlinico San Donato, University of Milan, Milan, Italy
    Fertil Steril 93:1741-4. 2010
    ..To assess whether routine renal ultrasonography may be recommended in all patients with pelvic endometriosis, in order to avoid silent ureteral involvement of the disease...
  49. ncbi Unoperated ovarian endometriomas and responsiveness to hyperstimulation
    Laura Benaglia
    Department of Obstetrics, Gynecology and Neonatology, Fondazione Cà Granda, Ospedale Maggiore Policlinico, Via M Fanti, 6, 20122 Milan, Italy
    Hum Reprod 26:1356-61. 2011
    ..The main aim of this study was to compare the number of developing follicles in the affected ovary with that in the contralateral intact gonad as a control...
  50. ncbi The use and effectiveness of in vitro fertilization in women with endometriosis: the surgeon's perspective
    Edgardo Somigliana
    Department of Obstetrics and Gynecology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Fertil Steril 91:1775-9. 2009
    ..To assess the use and effectiveness of IVF in a cohort of women undergoing surgery for endometriosis...
  51. ncbi The impact of IVF procedures on endometriosis recurrence
    Laura Benaglia
    Infertility Unit, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Eur J Obstet Gynecol Reprod Biol 148:49-52. 2010
    ..Thus, since available data on this issue are scanty and controversial, an observational study has been herein conducted in order to clarify this issue...
  52. ncbi Surgical excision of endometriomas and ovarian reserve: a systematic review on serum antimüllerian hormone level modifications
    Edgardo Somigliana
    Fondazione Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy
    Fertil Steril 98:1531-8. 2012
    ..To evaluate serum antimüllerian hormone (AMH) level modification after surgical excision of ovarian endometriomas...
  53. ncbi Perinatal environment and endometriosis
    Edgardo Somigliana
    Department of Obstetrics, Gynecology and Neonatology, Fondazione Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy
    Gynecol Obstet Invest 72:135-40. 2011
    ..Perinatal environmental exposure may affect fetal development and reprogram the developing organism for adult-onset disease. In this case-control study, we aimed at assessing this pathogenetic model in endometriosis...
  54. ncbi Should endometriomas be treated before IVF-ICSI cycles?
    Edgardo Somigliana
    Department of Obstetrics, Gynecology and Neonatology, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Hum Reprod Update 12:57-64. 2006
    ..Alternative therapeutical options include medical treatment and ultrasound-guided aspiration. Whereas prolonged GnRH agonist down-regulation may be beneficial, data on ultrasound aspiration are more controversial...
  55. ncbi Bias versus causality: interpreting recent evidence of association between endometriosis and ovarian cancer
    Paola Vigano
    Department of Obstetrics and Gynecology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Fertil Steril 88:588-93. 2007
    ..To establish whether causality versus biases may explain the association of endometriosis and ovarian cancer...
  56. ncbi Recurrent endometrioma and ovarian reserve: biological connection or surgical paradox?
    Edgardo Somigliana
    Department of Obstetrics, Gynecology, and Neonatology, Fondazione Instituto di Ricovero e Cura a Carattere Scientifico Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy
    Am J Obstet Gynecol 204:529.e1-5. 2011
    ..On these bases, we have hypothesized that the risk of recurrence may be related to the residual ovarian reserve of the operated ovary...
  57. ncbi Endometriosis and estroprogestins: the chicken or the egg causality dilemma
    Edgardo Somigliana
    Department of Obstetrics, Gynecology, and Neonatology, Fondazione Cà Granda, Milan, Italy
    Fertil Steril 95:431-3. 2011
    ..This might explain the previously reported mild association between endometriosis and past use of oral contraceptives...
  58. ncbi The outcomes of repeat surgery for recurrent symptomatic endometriosis
    Nicola Berlanda
    Luigi Mangiagalli Department of Obstetrics and Gynecology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Universita di Milano, Via della Commenda, 12 20122 Milano, Italy
    Curr Opin Obstet Gynecol 22:320-5. 2010
    ..To evaluate the efficacy of second-line surgery in the management of recurrent endometriosis...
  59. ncbi Rate of severe ovarian damage following surgery for endometriomas
    Laura Benaglia
    Infertility Unit, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via M Fanti 6, 20122 Milan, Italy
    Hum Reprod 25:678-82. 2010
    ..Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ovarian hyperstimulation. In this study, we aimed to determine the rate of this complication...
  60. ncbi 'Here comes the sun': pigmentary traits and sun habits in women with endometriosis
    Edgardo Somigliana
    Department of Obstetrics, Gynecology and Neonatology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Hum Reprod 25:728-33. 2010
    ..There is limited but interesting evidence suggesting that endometriosis may be associated with specific pigmentary traits and sun habits. In this case-control study, we aimed to further clarify this point...
  61. ncbi "You are so beautiful"*: behind women's attractiveness towards the biology of reproduction: a narrative review
    Laura Buggio
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, Universita degli Studi, and Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Gynecol Endocrinol 28:753-7. 2012
    ..Intriguing associations are emerging between features of attractiveness and some reproductive disorders, as both are substantially influenced by sex steroid hormones...
  62. ncbi Endometriosis: epidemiology and aetiological factors
    Paola Vigano
    Second Department of Obstetrics and Gynecology and Istituto Auxologico Italiano, Cusano Milanino, University of Milan, Milano, Italy
    Best Pract Res Clin Obstet Gynaecol 18:177-200. 2004
    ....
  63. ncbi Ureteral and vesical endometriosis. Two different clinical entities sharing the same pathogenesis
    Nicola Berlanda
    Department Chair, Department of Obstetrics and Gynecology, Istituto Luigi Mangiagalli, University of Milan, Italy
    Obstet Gynecol Surv 64:830-42. 2009
    ....
  64. ncbi Plasminogen activator inhibitor-1 4G/5G polymorphism and susceptibility to endometriosis in the Italian population
    Davide Gentilini
    Molecular Biology Laboratory, IRCCS Istituto Auxologico Italiano, Milan, Italy
    Eur J Obstet Gynecol Reprod Biol 146:219-21. 2009
    ..To clarify this issue, we have examined the prevalence of this polymorphism in a case-control study in the Italian population...
  65. ncbi The role of myomectomy in fertility enhancement
    Edgardo Somigliana
    Department of Obstetrics and Gynecology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Curr Opin Obstet Gynecol 20:379-85. 2008
    ..Pregnancy complications related to the presence of these lesions and to their removal are also addressed...
  66. ncbi Evidence for asymmetric distribution of lower intestinal tract endometriosis
    Paolo Vercellini
    First Department of Obstetrics and Gynecology, University of Milan, Italy
    BJOG 111:1213-7. 2004
  67. ncbi Non-invasive diagnosis of endometriosis: the goal or own goal?
    Edgardo Somigliana
    Department of Obstetrics, Gynecology and Neonatology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
    Hum Reprod 25:1863-8. 2010
    ..In particular, we emphasize that this instrument may be of benefit provided that the test is not used as a screening test...
  68. ncbi Endometriotic ovarian cysts negatively affect the rate of spontaneous ovulation
    Laura Benaglia
    Infertility Unit, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via M Fanti 6, 20122 Milan, Italy
    Hum Reprod 24:2183-6. 2009
    ..To clarify this aspect, we set up a prospective study in women with monolateral endometriomas in order to assess the rate of ovulation in affected ovaries...
  69. ncbi Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence
    Edgardo Somigliana
    Department of Obstetrics, Gynecology and Neonatology, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Via Commenda 12, 20122 Milan, Italy
    Gynecol Oncol 101:331-41. 2006
    ..On the basis of the present findings, modifications of the standard treatment options for the disease are not justifiable...
  70. ncbi Bladder endometriosis: getting closer and closer to the unifying metastatic hypothesis
    Edgardo Somigliana
    Department of Obstetrics and Gynecology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Fertil Steril 87:1287-90. 2007
    ..The aim of the study was to evaluate the presence of other forms of endometriosis in patients with bladder endometriotic nodules...
  71. ncbi Bladder psoas hitch in hydronephrosis due to pelvic endometriosis: outcome of urodynamic parameters
    Luca Carmignani
    Urology Unit, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, San Donato Milanese, Milan, Italy
    Fertil Steril 92:35-40. 2009
    ..To evaluate modifications in bladder sensitivity and function after ureteroneocystostomy with bladder psoas hitch for hydronephrosis due to deep pelvic endometriosis...
  72. ncbi Gonadotropin-releasing hormone agonist treatment before abdominal myomectomy: a controlled trial
    Paolo Vercellini
    Clinica Ostetrica e Ginecologica I, Istituto Luigi Mangiagalli, University of Milan, Milan, Italy
    Fertil Steril 79:1390-5. 2003
    ..To ascertain whether adjuvant gonadotropin-releasing hormone (GnRH) agonist therapy decreases blood loss during abdominal myomectomy...
  73. ncbi Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis
    Paola Vigano
    Department of Obstetrics, Gynecology and Neonatology, Fondazione Policlinico Mangiagalli Regina Elena, Milan, Italy
    Hum Reprod Update 12:77-89. 2006
    ..Based on these data, the causal link between endometriosis and ovarian endometrioid/clear cell carcinomas remains to be defined both in terms of entity of association and of underlying molecular mechanisms...
  74. ncbi Buserelin versus danazol in the treatment of endometriosis-associated infertility
    L Fedele
    First Department of Obstetrics and Gynecology, University of Milan, Italy
    Am J Obstet Gynecol 161:871-6. 1989
    ..The results of this study suggests that buserelin is at least as effective as danazol in the treatment of endometriosis when the outcome is considered in terms of restored fertility, and its side effects are less severe...
  75. ncbi Determinants of reproductive outcome after abdominal myomectomy for infertility
    P Vercellini
    Clinica Ostetrica e Ginecologica Luigi Mangiagalli, University of Milano and Istituti Clinici di Perfezionamento, Italy
    Fertil Steril 72:109-14. 1999
    ..To determine the effect of myomectomy as a therapy for infertility and to define the factors that influence reproductive outcome...
  76. ncbi Hysteroscopic myomectomy: long-term effects on menstrual pattern and fertility
    P Vercellini
    Clinica Ostetrica e Ginecologica Luigi Mangiagalli, University of Milan, Italy
    Obstet Gynecol 94:341-7. 1999
    ..To determine the effects of hysteroscopic myomectomy on menorrhagia and infertility and the influence of intramural extension on surgical feasibility and long-term outcomes...
  77. ncbi A levonorgestrel-releasing intrauterine system for the treatment of dysmenorrhea associated with endometriosis: a pilot study
    P Vercellini
    Clinica Ostetrica e Ginecologica Luigi Mangiagalli, University of Milano, Italy
    Fertil Steril 72:505-8. 1999
    ..To evaluate the efficacy and safety of an intrauterine system releasing 20 microg of levonorgestrel per 24 hours in the long-term treatment of recurrent dysmenorrhea in women already operated on conservatively for endometriosis...
  78. ncbi Fibroids and female reproduction: a critical analysis of the evidence
    E Somigliana
    Department of Obstetrics and Gynecology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 12, 20122 Milan, Italy
    Hum Reprod Update 13:465-76. 2007
    ....
  79. ncbi Comparison of cyproterone acetate and danazol in the treatment of pelvic pain associated with endometriosis
    L Fedele
    1st Department of Obstetrics and Gynecology, University of Milan, Italy
    Obstet Gynecol 73:1000-4. 1989
    ..Deep dyspareunia was less affected by treatment, and 6 months later had recurred in all the women.(ABSTRACT TRUNCATED AT 250 WORDS)..
  80. ncbi [Progestogens and estroprogestins in the treatment of pelvic pain associated with endometriosis]
    R Daguati
    Clinica Ostetrica e Ginecologica, Istituto Luigi Mangiagalli, , Milano, Italy
    Minerva Ginecol 58:499-510. 2006
    ..However, their contraceptive effectiveness limits their use to women who do not wish to have children in the short-term...
  81. ncbi Endometrial patterns during therapy with danazol or gestrinone for endometriosis: structural and ultrastructural study
    M Marchini
    Istituto Ostetrico Ginecologico II, Universita di Milano, Italy
    Hum Pathol 23:51-6. 1992
    ..Long-term treatment with danazol caused endometrial atrophy similar to that induced by gestrinone, but it appeared earlier; thus, the former drug seems preferable in short-term treatment...
  82. ncbi Vitamin D reserve is higher in women with endometriosis
    Edgardo Somigliana
    Infertility Unit, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via M Fanti 6, 20122 Milan, Italy
    Hum Reprod 22:2273-8. 2007
    ..Since vitamin D is an effective modulator of the immune system, we have hypothesized that the vitamin D status may have a role in the pathogenesis of endometriosis...
  83. ncbi Medical treatment of mild endometriosis in infertile women: analysis of a failure
    G B Candiani
    First Department of Obstetrics and Gynaecology, University of Milan School of Medicine, Italy
    Hum Reprod 5:901-5. 1990
    ..However, no study comparing medically treated with untreated women has ever shown any drug to be more effective than expectant management. The possible explanations of treatment failures are reviewed...
  84. ncbi Uterine fibroids and gynecologic pain symptoms in a population-based study
    Sheri A Lippman
    School of Public Health, University of California at Berkeley, Berkeley, California 94720-7360, USA
    Fertil Steril 80:1488-94. 2003
    ..Fibroid-associated pain symptomatology in a non-care-seeking population may be different from that of a clinic population...
  85. ncbi Serum dioxin concentrations and risk of uterine leiomyoma in the Seveso Women's Health Study
    Brenda Eskenazi
    Department of Epidemiology, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
    Am J Epidemiol 166:79-87. 2007
    ..0 parts per trillion. This finding suggests that TCDD may have antiestrogenic effects in the uterine myometrium, in contrast to apparently estrogenic effects previously found in the breast of Seveso Women's Health Study women...
  86. ncbi Management of ovarian endometriomas
    Charles Chapron
    Assistance Publique, Hopitaux de Paris AP HP, Clinique Universitaire Baudelocque, CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod Update 8:591-7. 2002
    ..In case of infertility, the management of endometriomas is controversial. Recurrent ovarian surgery is not recommended...
  87. ncbi Lateral distribution of recurrent ovarian endometriotic cysts
    Paolo Vercellini
    Fertil Steril 77:848-9. 2002
  88. ncbi Serum dioxin concentrations and endometriosis: a cohort study in Seveso, Italy
    Brenda Eskenazi
    Center for Children s Environmental Health, School of Public Health, University of California at Berkeley, Berkeley, California 94720, USA
    Environ Health Perspect 110:629-34. 2002
    ..Unavoidable disease misclassification in a population-based study may have led to an underestimate of the true risk of endometriosis...