Maria Grazia Valsecchi

Summary

Affiliation: University of Milano-Bicocca
Country: Italy

Publications

  1. pmc Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a randomized controlled trial
    Paolo Zamboni
    Vascular Diseases Center, University of Ferrara, C so Giovecca 203, 44100 Ferrara, Italy
    Trials 13:183. 2012
  2. pmc Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutrition
    Valentina Bozzetti
    Department of Neonatal Intensive Care, MBBM Foundation, San Gerardo Hospital, Via Pergolesi 33, 20900 Monza, Italy
    BMC Pediatr 12:106. 2012
  3. pmc Multivariate permutation test to compare survival curves for matched data
    Stefania Galimberti
    Center of Biostatistics for Clinical Epidemiology, Department of Health Sciences, University of Milano Bicocca, 20900, Monza, Italy
    BMC Med Res Methodol 13:16. 2013
  4. doi request reprint Cancer registration in developing countries: luxury or necessity?
    Maria Grazia Valsecchi
    Centre of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Milan, Italy
    Lancet Oncol 9:159-67. 2008
  5. ncbi request reprint Web-based international studies in limited populations of pediatric leukemia
    Maria Grazia Valsecchi
    Unit of Medical Statistics, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Via Cadore, Monza MI, Italy
    Pediatr Blood Cancer 50:270-3. 2008
  6. doi request reprint Oxidative stress biomarkers and chromogranin A in uremic patients: effects of dialytic treatment
    Giovanna Castoldi
    Clinica Nefrologica, Azienda Ospedaliera San Gerardo, Dipartimento di Medicina Clinica e Prevenzione, Universita degli Studi di Milano Bicocca, Monza, Italy
    Clin Biochem 43:1387-92. 2010
  7. doi request reprint Hypertension, prehypertension, and transient elevated blood pressure in children: association with weight excess and waist circumference
    Simonetta Genovesi
    Department of Clinical Medicine and Prevention, Nephrology Unit, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy
    Am J Hypertens 23:756-61. 2010
  8. doi request reprint Usefulness of waist circumference for the identification of childhood hypertension
    Simonetta Genovesi
    Department of Clinical and Preventive Medicine, University of Milano Bicocca, Monza, Italy
    J Hypertens 26:1563-70. 2008
  9. doi request reprint Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project
    Alberto Piperno
    Department of Clinical Medicine and Prevention, University of Milano Bicocca and S Gerardo Hospital, Monza, Italy
    Blood 117:2953-9. 2011
  10. doi request reprint Robust non-parametric one-sample tests for the analysis of recurrent events
    Paola Rebora
    Department of Clinical Medicine and Prevention, Center of Biostatistics for Clinical Epidemiology, University of Milano Bicocca, Via Cadore 48 20052, Monza, Italy
    Stat Med 29:3137-46. 2010

Detail Information

Publications36

  1. pmc Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a randomized controlled trial
    Paolo Zamboni
    Vascular Diseases Center, University of Ferrara, C so Giovecca 203, 44100 Ferrara, Italy
    Trials 13:183. 2012
    ..Data from a few small case series suggest possible improvement of the clinical course and quality of life by performing percutaneous balloon angioplasty (PTA) of the stenotic veins...
  2. pmc Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutrition
    Valentina Bozzetti
    Department of Neonatal Intensive Care, MBBM Foundation, San Gerardo Hospital, Via Pergolesi 33, 20900 Monza, Italy
    BMC Pediatr 12:106. 2012
    ..In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and the best rate of delivering the enteral nutrition...
  3. pmc Multivariate permutation test to compare survival curves for matched data
    Stefania Galimberti
    Center of Biostatistics for Clinical Epidemiology, Department of Health Sciences, University of Milano Bicocca, 20900, Monza, Italy
    BMC Med Res Methodol 13:16. 2013
    ..When there is a limited set of cases receiving the experimental treatment, matching of a proper set of controls in a non fixed proportion is convenient...
  4. doi request reprint Cancer registration in developing countries: luxury or necessity?
    Maria Grazia Valsecchi
    Centre of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Milan, Italy
    Lancet Oncol 9:159-67. 2008
    ..In this Review, we advocate the need for availability of cancer data and discuss potential opportunities for hospital-based and population-based cancer registries to collaborate in providing these data in low-income countries...
  5. ncbi request reprint Web-based international studies in limited populations of pediatric leukemia
    Maria Grazia Valsecchi
    Unit of Medical Statistics, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Via Cadore, Monza MI, Italy
    Pediatr Blood Cancer 50:270-3. 2008
    ....
  6. doi request reprint Oxidative stress biomarkers and chromogranin A in uremic patients: effects of dialytic treatment
    Giovanna Castoldi
    Clinica Nefrologica, Azienda Ospedaliera San Gerardo, Dipartimento di Medicina Clinica e Prevenzione, Universita degli Studi di Milano Bicocca, Monza, Italy
    Clin Biochem 43:1387-92. 2010
    ..To evaluate oxidative stress in uremia and dialysis and chromogranin A, a stress hormone that could be related to oxidative processes...
  7. doi request reprint Hypertension, prehypertension, and transient elevated blood pressure in children: association with weight excess and waist circumference
    Simonetta Genovesi
    Department of Clinical Medicine and Prevention, Nephrology Unit, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy
    Am J Hypertens 23:756-61. 2010
    ..To assess the prevalence of hypertension (H), prehypertension (PH), and transient elevated blood pressure (TH) and their relationship with weight class and waist circumference (WC) in an unselected population of Northern Italian children...
  8. doi request reprint Usefulness of waist circumference for the identification of childhood hypertension
    Simonetta Genovesi
    Department of Clinical and Preventive Medicine, University of Milano Bicocca, Monza, Italy
    J Hypertens 26:1563-70. 2008
    ..To investigate the ability of BMI and waist circumference, single and combined, in identifying children who are at risk of hypertension and in influencing absolute blood pressure values...
  9. doi request reprint Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project
    Alberto Piperno
    Department of Clinical Medicine and Prevention, University of Milano Bicocca and S Gerardo Hospital, Monza, Italy
    Blood 117:2953-9. 2011
    ..The combined and significant changes in other variables probably contribute to the suppression of hepcidin in this setting...
  10. doi request reprint Robust non-parametric one-sample tests for the analysis of recurrent events
    Paola Rebora
    Department of Clinical Medicine and Prevention, Center of Biostatistics for Clinical Epidemiology, University of Milano Bicocca, Via Cadore 48 20052, Monza, Italy
    Stat Med 29:3137-46. 2010
    ..Robust non-parametric one-sample tests for recurrent events can be useful to assess efficacy and especially safety in non-randomized studies or in epidemiological studies for comparison with a standard population...
  11. ncbi request reprint A weighted Kaplan-Meier estimator for matched data with application to the comparison of chemotherapy and bone-marrow transplant in leukaemia
    Stefania Galimberti
    Department of Clinical Medicine, Prevention and Biotechnology, Section of Medical Statistics, University of Milano Bicocca, Monza, Italy
    Stat Med 21:3847-64. 2002
    ..The procedures proposed here are applied to data collected from an Italian study whose aim was the evaluation of bone marrow transplant, as compared to intensive chemotherapy, in the cure of paediatric acute lymphoblastic leukaemia...
  12. doi request reprint Atrial fibrillation and morbidity and mortality in a cohort of long-term hemodialysis patients
    Simonetta Genovesi
    Dipartimento di Medicina Clinica e Prevenzione, Universita degli Studi di Milano Bicocca, Monza, Italy
    Am J Kidney Dis 51:255-62. 2008
    ..Atrial fibrillation is associated with increased mortality and hospitalization in the general population. Data about mortality, morbidity, and hospitalization in hemodialysis patients with atrial fibrillation are limited...
  13. doi request reprint Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
    Carlo Gambacorti-Passerini
    Hematology and Clinical Research Unit, San Gerardo Hospital, Italy
    J Natl Cancer Inst 103:553-61. 2011
    ..Imatinib slows development of chronic myeloid leukemia (CML). However, available information on morbidity and mortality is largely based on sponsored trials, whereas independent long-term field studies are lacking...
  14. ncbi request reprint Analysis of interval-censored longitudinal data with application to onco-haematology
    Paola de Lorenzo
    Biostatistics Center, Department of Clinical Medicine, Prevention and Biotechnology, University of Milano Bicocca, Monza MI, Italy
    Stat Med 24:3945-57. 2005
    ..Results show that the approach is promising as it allows proper description of the data, while maintaining flexibility of modelling, feasibility of computations and interpretability of results...
  15. ncbi request reprint Carotid plaque echolucency increases the risk of stroke in carotid stenting: the Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) study
    Giorgio M Biasi
    Department of Surgical Sciences and Intensive Care, University of Milan Bicocca, Bassini S Gerardo Teaching Hospital, Milan, Italy
    Circulation 110:756-62. 2004
    ..This is the first study to analyze the role of a computer-assisted highly reproducible index of echogenicity, namely the gray-scale median (GSM), on the risk of stroke during CAS...
  16. ncbi request reprint Association between serum values of C-reactive protein and cytokine production in whole blood of patients with type 2 diabetes
    Giovanna Castoldi
    Clinica Nefrologica, Az Ospedaliera San Gerardo, Monza, Italy
    Clin Sci (Lond) 113:103-8. 2007
    ....
  17. ncbi request reprint Effects of exercise training on heart rate and QT interval in healthy young individuals: are there gender differences?
    Simonetta Genovesi
    Dipartimento di Medicina Clinica Prevenzione e Biotecnologie, University of Milano Bicocca, Sanitarie, Via Cadore 48, 20052 Monza, Italy
    Europace 9:55-60. 2007
    ..The aim of the present study was to assess the effects of exercise training on heart rate, QT interval, and on the relation between ventricular repolarization and heart rate in men and women...
  18. ncbi request reprint Maternal perception of excess weight in children: a survey conducted by paediatricians in the province of Milan
    Simonetta Genovesi
    DIMEP Università degli Studi di Milano Bicocca, Monza, Italy
    Acta Paediatr 94:747-52. 2005
    ..To establish whether maternal perception of a child's body weight (BW) and food intake is related to the level of maternal education...
  19. doi request reprint Eligibility for allogeneic transplantation in very high risk childhood acute lymphoblastic leukemia: the impact of the waiting time
    Adriana Balduzzi
    Clinica Pediatrica Università degli Studi di Milano Bicocca, Ospedale San Gerardo, Via Pergolesi 33, 20052 Monza, Milan, Italy
    Haematologica 93:925-9. 2008
    ..The relative advantage of transplant from compatible related donors in very-high-risk childhood acute lymphoblastic leukemia was consistent for any time elapsed in first remission...
  20. doi request reprint Nutritional status at diagnosis is related to clinical outcomes in children and adolescents with cancer: a perspective from Central America
    Alessandra Sala
    Department of Pediatrics, S Gerardo Hospital, University of Milano Bicocca, Monza, Italy
    Eur J Cancer 48:243-52. 2012
    ....
  21. doi request reprint Are chronic myeloid leukemia patients more at risk for second malignancies? A population-based study
    Paola Rebora
    Center of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Monza, Italy
    Am J Epidemiol 172:1028-33. 2010
    ..These estimates constitute a relevant reference for future studies and a benchmark for comparisons with prognosis in CML patients after chronic use of tyrosine kinase inhibitors...
  22. doi request reprint Maternal polymorphisms for methyltetrahydrofolate reductase and methionine synthetase reductase and risk of children with Down syndrome
    Elisa Pozzi
    Department of Obstetrics and Gynecology, University of Milano Bicocca, S Gerardo Hospital, Monza, Italy
    Am J Obstet Gynecol 200:636.e1-6. 2009
    ..The purpose of this research was to study factors that are involved in centromeric hypomethylation in the pathogenesis of Down syndrome (DS)...
  23. doi request reprint Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
    Valentino Conter
    Department of Pediatrics, University of Milano Bicocca, Ospedale S Gerardo, Monza, Italy
    Blood 115:3206-14. 2010
    ..MRD response detected by sensitive quantitative PCR at 2 predefined TPs is highly predictive for relapse in childhood pB-ALL. The study is registered at http://clinicaltrials.gov: NCT00430118 for BFM and NCT00613457 for AIEOP...
  24. ncbi request reprint Epidemiology and survival analysis of cystic fibrosis in an area of intense neonatal screening over 30 years
    Baroukh M Assael
    Cystic Fibrosis Center, Verona, Italy
    Am J Epidemiol 156:397-401. 2002
    ..They could not conclude that neonatal screening improves long-term survival if compared with diagnosis by symptoms in early infancy...
  25. ncbi request reprint Survival after relapse in children with solid tumors: a follow-up study from the Italian off-therapy registry
    Stefano Ceschel
    Department of Pediatrics, S Dona di Piave, Venezia, Italy
    Pediatr Blood Cancer 47:560-6. 2006
    ....
  26. ncbi request reprint Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part I
    Scott C Howard
    International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
    Pediatr Blood Cancer 48:364-9. 2007
    ..cure4kids.org. Identifying preventable causes of abandonment of therapy and documenting the nutritional status of patients treated at MISPHO centers are areas of active research...
  27. ncbi request reprint Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response
    Giovanni Cazzaniga
    Centro Ricerca M Tettamanti, Clinica Pediatrica Università di Milano Bicocca, Monza, Italy
    Br J Haematol 119:445-53. 2002
    ..This provides useful information on the capability of chemotherapy to reduce the leukaemic clone, with prognostic implications...
  28. ncbi request reprint Outcome of very late relapse in children with acute lymphoblastic leukemia
    Carmelo Rizzari
    Pediatric Department of Monza, Italy
    Haematologica 89:427-34. 2004
    ..The present study was aimed at investigating clinical features and treatment outcome of children with very late relapse, diagnosed and treated in Italy in the last 20 years...
  29. doi request reprint Acute lymphoblastic leukemia and Down syndrome: presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)
    Maurizio Arico
    Pediatric Hematology and Oncology, Children Hospital A O U Meyer, Florence, Italy
    Cancer 113:515-21. 2008
    ..The presenting features and treatment outcome of 120 patients with Down syndrome (DS) and childhood acute lymphoblastic leukemia (ALL) were compared with 6237 non-DS patients treated in the same years...
  30. doi request reprint A randomized, double-masked, placebo-controlled clinical trial of multivitamin supplementation for age-related lens opacities. Clinical trial of nutritional supplements and age-related cataract report no. 3
    Giovanni Maraini
    Ophthalmology 115:599-607.e1. 2008
    ..To evaluate the effect of a multivitamin/mineral supplement on development or progression of age-related lens opacities...
  31. doi request reprint Improving recruitment to clinical trials for cancer in childhood
    Kathy Pritchard-Jones
    Section of Paediatric Oncology Children s Unit, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
    Lancet Oncol 9:392-9. 2008
    ..The introduction of new paediatric regulations in Canada and the USA and Europe should encourage manufacturers of new anticancer drugs to lend support to clinical trials of cancer in childhood...
  32. doi request reprint Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy
    Maurizio Arico
    Pediatric Hematology Oncology, Ospedale dei Bambini G Di Cristina, Palermo, Italy
    J Clin Oncol 26:283-9. 2008
    ..The prognostic value of DNA index was explored in this setting...
  33. ncbi request reprint Transplantation in childhood very high risk acute lymphoblastic leukemia in first complete remission: where are we now?
    Adriana Balduzzi
    J Clin Oncol 25:2625-6; author reply 2627-8. 2007
  34. ncbi request reprint Long term survivors of childhood cancer: cure and care. The Erice statement
    Riccardo Haupt
    Epidemiology and Biostatistics Section, Gaslini Children Hospital, Genova, Italy
    Eur J Cancer 43:1778-80. 2007
    ..The ten points reflect what the group considers essential in the survivors' cure and care...
  35. ncbi request reprint Importance of minimal residual disease testing during the second year of disease: still no answer?
    Maurizio Arico
    J Clin Oncol 21:4463-4; author reply 4464-5. 2003
  36. ncbi request reprint Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol II
    Maurizio Arico
    Onco Ematologia Pediatrica, Ospedale dei Bambini G Di Cristina, Palermo, Italy
    Blood 100:420-6. 2002
    ..This modified therapy may lead to high cure rates for patients defined as at high risk for intrinsic resistance to corticosteroids only...