Maria Grazia Valsecchi
Affiliation: University of Milano-Bicocca
- Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a randomized controlled trialPaolo Zamboni
Vascular Diseases Center, University of Ferrara, C so Giovecca 203, 44100 Ferrara, Italy
Trials 13:183. 2012..Data from a few small case series suggest possible improvement of the clinical course and quality of life by performing percutaneous balloon angioplasty (PTA) of the stenotic veins...
- Evaluation of splanchnic oximetry, Doppler flow velocimetry in the superior mesenteric artery and feeding tolerance in very low birth weight IUGR and non-IUGR infants receiving bolus versus continuous enteral nutritionValentina Bozzetti
Department of Neonatal Intensive Care, MBBM Foundation, San Gerardo Hospital, Via Pergolesi 33, 20900 Monza, Italy
BMC Pediatr 12:106. 2012..In literature there is no consensus regarding the impact of enteral feeding on intestinal blood flow and hence regarding the best regimen and the best rate of delivering the enteral nutrition...
- Multivariate permutation test to compare survival curves for matched dataStefania Galimberti
Center of Biostatistics for Clinical Epidemiology, Department of Health Sciences, University of Milano Bicocca, 20900, Monza, Italy
BMC Med Res Methodol 13:16. 2013..When there is a limited set of cases receiving the experimental treatment, matching of a proper set of controls in a non fixed proportion is convenient...
- Cancer registration in developing countries: luxury or necessity?Maria Grazia Valsecchi
Centre of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Milan, Italy
Lancet Oncol 9:159-67. 2008..In this Review, we advocate the need for availability of cancer data and discuss potential opportunities for hospital-based and population-based cancer registries to collaborate in providing these data in low-income countries...
- Web-based international studies in limited populations of pediatric leukemiaMaria Grazia Valsecchi
Unit of Medical Statistics, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Via Cadore, Monza MI, Italy
Pediatr Blood Cancer 50:270-3. 2008....
- Oxidative stress biomarkers and chromogranin A in uremic patients: effects of dialytic treatmentGiovanna Castoldi
Clinica Nefrologica, Azienda Ospedaliera San Gerardo, Dipartimento di Medicina Clinica e Prevenzione, Universita degli Studi di Milano Bicocca, Monza, Italy
Clin Biochem 43:1387-92. 2010..To evaluate oxidative stress in uremia and dialysis and chromogranin A, a stress hormone that could be related to oxidative processes...
- Hypertension, prehypertension, and transient elevated blood pressure in children: association with weight excess and waist circumferenceSimonetta Genovesi
Department of Clinical Medicine and Prevention, Nephrology Unit, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy
Am J Hypertens 23:756-61. 2010..To assess the prevalence of hypertension (H), prehypertension (PH), and transient elevated blood pressure (TH) and their relationship with weight class and waist circumference (WC) in an unselected population of Northern Italian children...
- Usefulness of waist circumference for the identification of childhood hypertensionSimonetta Genovesi
Department of Clinical and Preventive Medicine, University of Milano Bicocca, Monza, Italy
J Hypertens 26:1563-70. 2008..To investigate the ability of BMI and waist circumference, single and combined, in identifying children who are at risk of hypertension and in influencing absolute blood pressure values...
- Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE projectAlberto Piperno
Department of Clinical Medicine and Prevention, University of Milano Bicocca and S Gerardo Hospital, Monza, Italy
Blood 117:2953-9. 2011..The combined and significant changes in other variables probably contribute to the suppression of hepcidin in this setting...
- Robust non-parametric one-sample tests for the analysis of recurrent eventsPaola Rebora
Department of Clinical Medicine and Prevention, Center of Biostatistics for Clinical Epidemiology, University of Milano Bicocca, Via Cadore 48 20052, Monza, Italy
Stat Med 29:3137-46. 2010..Robust non-parametric one-sample tests for recurrent events can be useful to assess efficacy and especially safety in non-randomized studies or in epidemiological studies for comparison with a standard population...
- A weighted Kaplan-Meier estimator for matched data with application to the comparison of chemotherapy and bone-marrow transplant in leukaemiaStefania Galimberti
Department of Clinical Medicine, Prevention and Biotechnology, Section of Medical Statistics, University of Milano Bicocca, Monza, Italy
Stat Med 21:3847-64. 2002..The procedures proposed here are applied to data collected from an Italian study whose aim was the evaluation of bone marrow transplant, as compared to intensive chemotherapy, in the cure of paediatric acute lymphoblastic leukaemia...
- Atrial fibrillation and morbidity and mortality in a cohort of long-term hemodialysis patientsSimonetta Genovesi
Dipartimento di Medicina Clinica e Prevenzione, Universita degli Studi di Milano Bicocca, Monza, Italy
Am J Kidney Dis 51:255-62. 2008..Atrial fibrillation is associated with increased mortality and hospitalization in the general population. Data about mortality, morbidity, and hospitalization in hemodialysis patients with atrial fibrillation are limited...
- Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinibCarlo Gambacorti-Passerini
Hematology and Clinical Research Unit, San Gerardo Hospital, Italy
J Natl Cancer Inst 103:553-61. 2011..Imatinib slows development of chronic myeloid leukemia (CML). However, available information on morbidity and mortality is largely based on sponsored trials, whereas independent long-term field studies are lacking...
- Analysis of interval-censored longitudinal data with application to onco-haematologyPaola de Lorenzo
Biostatistics Center, Department of Clinical Medicine, Prevention and Biotechnology, University of Milano Bicocca, Monza MI, Italy
Stat Med 24:3945-57. 2005..Results show that the approach is promising as it allows proper description of the data, while maintaining flexibility of modelling, feasibility of computations and interpretability of results...
- Carotid plaque echolucency increases the risk of stroke in carotid stenting: the Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) studyGiorgio M Biasi
Department of Surgical Sciences and Intensive Care, University of Milan Bicocca, Bassini S Gerardo Teaching Hospital, Milan, Italy
Circulation 110:756-62. 2004..This is the first study to analyze the role of a computer-assisted highly reproducible index of echogenicity, namely the gray-scale median (GSM), on the risk of stroke during CAS...
- Association between serum values of C-reactive protein and cytokine production in whole blood of patients with type 2 diabetesGiovanna Castoldi
Clinica Nefrologica, Az Ospedaliera San Gerardo, Monza, Italy
Clin Sci (Lond) 113:103-8. 2007....
- Effects of exercise training on heart rate and QT interval in healthy young individuals: are there gender differences?Simonetta Genovesi
Dipartimento di Medicina Clinica Prevenzione e Biotecnologie, University of Milano Bicocca, Sanitarie, Via Cadore 48, 20052 Monza, Italy
Europace 9:55-60. 2007..The aim of the present study was to assess the effects of exercise training on heart rate, QT interval, and on the relation between ventricular repolarization and heart rate in men and women...
- Maternal perception of excess weight in children: a survey conducted by paediatricians in the province of MilanSimonetta Genovesi
DIMEP Università degli Studi di Milano Bicocca, Monza, Italy
Acta Paediatr 94:747-52. 2005..To establish whether maternal perception of a child's body weight (BW) and food intake is related to the level of maternal education...
- Eligibility for allogeneic transplantation in very high risk childhood acute lymphoblastic leukemia: the impact of the waiting timeAdriana Balduzzi
Clinica Pediatrica Università degli Studi di Milano Bicocca, Ospedale San Gerardo, Via Pergolesi 33, 20052 Monza, Milan, Italy
Haematologica 93:925-9. 2008..The relative advantage of transplant from compatible related donors in very-high-risk childhood acute lymphoblastic leukemia was consistent for any time elapsed in first remission...
- Nutritional status at diagnosis is related to clinical outcomes in children and adolescents with cancer: a perspective from Central AmericaAlessandra Sala
Department of Pediatrics, S Gerardo Hospital, University of Milano Bicocca, Monza, Italy
Eur J Cancer 48:243-52. 2012....
- Are chronic myeloid leukemia patients more at risk for second malignancies? A population-based studyPaola Rebora
Center of Biostatistics for Clinical Epidemiology, Department of Clinical Medicine and Prevention, University of Milano Bicocca, Monza, Italy
Am J Epidemiol 172:1028-33. 2010..These estimates constitute a relevant reference for future studies and a benchmark for comparisons with prognosis in CML patients after chronic use of tyrosine kinase inhibitors...
- Maternal polymorphisms for methyltetrahydrofolate reductase and methionine synthetase reductase and risk of children with Down syndromeElisa Pozzi
Department of Obstetrics and Gynecology, University of Milano Bicocca, S Gerardo Hospital, Monza, Italy
Am J Obstet Gynecol 200:636.e1-6. 2009..The purpose of this research was to study factors that are involved in centromeric hypomethylation in the pathogenesis of Down syndrome (DS)...
- Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 studyValentino Conter
Department of Pediatrics, University of Milano Bicocca, Ospedale S Gerardo, Monza, Italy
Blood 115:3206-14. 2010..MRD response detected by sensitive quantitative PCR at 2 predefined TPs is highly predictive for relapse in childhood pB-ALL. The study is registered at http://clinicaltrials.gov: NCT00430118 for BFM and NCT00613457 for AIEOP...
- Epidemiology and survival analysis of cystic fibrosis in an area of intense neonatal screening over 30 yearsBaroukh M Assael
Cystic Fibrosis Center, Verona, Italy
Am J Epidemiol 156:397-401. 2002..They could not conclude that neonatal screening improves long-term survival if compared with diagnosis by symptoms in early infancy...
- Survival after relapse in children with solid tumors: a follow-up study from the Italian off-therapy registryStefano Ceschel
Department of Pediatrics, S Dona di Piave, Venezia, Italy
Pediatr Blood Cancer 47:560-6. 2006....
- Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part IScott C Howard
International Outreach Program and Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee, USA
Pediatr Blood Cancer 48:364-9. 2007..cure4kids.org. Identifying preventable causes of abandonment of therapy and documenting the nutritional status of patients treated at MISPHO centers are areas of active research...
- Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment responseGiovanni Cazzaniga
Centro Ricerca M Tettamanti, Clinica Pediatrica Università di Milano Bicocca, Monza, Italy
Br J Haematol 119:445-53. 2002..This provides useful information on the capability of chemotherapy to reduce the leukaemic clone, with prognostic implications...
- Outcome of very late relapse in children with acute lymphoblastic leukemiaCarmelo Rizzari
Pediatric Department of Monza, Italy
Haematologica 89:427-34. 2004..The present study was aimed at investigating clinical features and treatment outcome of children with very late relapse, diagnosed and treated in Italy in the last 20 years...
- Acute lymphoblastic leukemia and Down syndrome: presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)Maurizio Arico
Pediatric Hematology and Oncology, Children Hospital A O U Meyer, Florence, Italy
Cancer 113:515-21. 2008..The presenting features and treatment outcome of 120 patients with Down syndrome (DS) and childhood acute lymphoblastic leukemia (ALL) were compared with 6237 non-DS patients treated in the same years...
- A randomized, double-masked, placebo-controlled clinical trial of multivitamin supplementation for age-related lens opacities. Clinical trial of nutritional supplements and age-related cataract report no. 3Giovanni Maraini
Ophthalmology 115:599-607.e1. 2008..To evaluate the effect of a multivitamin/mineral supplement on development or progression of age-related lens opacities...
- Improving recruitment to clinical trials for cancer in childhoodKathy Pritchard-Jones
Section of Paediatric Oncology Children s Unit, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK
Lancet Oncol 9:392-9. 2008..The introduction of new paediatric regulations in Canada and the USA and Europe should encourage manufacturers of new anticancer drugs to lend support to clinical trials of cancer in childhood...
- Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapyMaurizio Arico
Pediatric Hematology Oncology, Ospedale dei Bambini G Di Cristina, Palermo, Italy
J Clin Oncol 26:283-9. 2008..The prognostic value of DNA index was explored in this setting...
- Transplantation in childhood very high risk acute lymphoblastic leukemia in first complete remission: where are we now?Adriana Balduzzi
J Clin Oncol 25:2625-6; author reply 2627-8. 2007
- Long term survivors of childhood cancer: cure and care. The Erice statementRiccardo Haupt
Epidemiology and Biostatistics Section, Gaslini Children Hospital, Genova, Italy
Eur J Cancer 43:1778-80. 2007..The ten points reflect what the group considers essential in the survivors' cure and care...
- Importance of minimal residual disease testing during the second year of disease: still no answer?Maurizio Arico
J Clin Oncol 21:4463-4; author reply 4464-5. 2003
- Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol IIMaurizio Arico
Onco Ematologia Pediatrica, Ospedale dei Bambini G Di Cristina, Palermo, Italy
Blood 100:420-6. 2002..This modified therapy may lead to high cure rates for patients defined as at high risk for intrinsic resistance to corticosteroids only...