Research Topics
| Franco ValenzaSummaryAffiliation: University of Milan Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Sodium bicarbonate treatment during transient or sustained lactic acidemia in normoxic and normotensive ratsFranco Valenza
Dipartimento di Anestesia, Rianimazione e Terapia del Dolore, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy
PLoS ONE 7:e46035. 2012..We set up an experimental model of lactic acid infusion in normoxic and normotensive rats to investigate the systemic effects of lactic acidemia per se without the confounding factor of an underlying organic cause of acidosis...
Extracorporeal lung perfusion and ventilation to improve donor lung function and increase the number of organs available for transplantationF Valenza
Dipartimento di Anestesia, Terapia Intensiva e Subintensiva e Terapia del Dolore, Universita degli Studi di Milano, Milano, Italy
Transplant Proc 44:1826-9. 2012..Ex vivo lung perfusion (EVLP) has been validated as a valuable technique to increase the pool of organs available for lung transplantation...- β-adrenergic agonist infusion during extracorporeal lung perfusion: effects on glucose concentration in the perfusion fluid and on lung functionFranco Valenza
Dipartimento di Anestesia, Terapia Intensiva e Subintensiva e Terapia del Dolore, Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Ca Granda Ospedale Maggiore Policlinico, Via F Sforza 35, Milan, Italy
J Heart Lung Transplant 31:524-30. 2012..We investigated whether salbutamol, a β-adrenergic receptor agonist known to upregulate fluid transport in the lung, modulates glucose concentration in the perfusate during EVLP... 
Management of mechanical ventilation during laparoscopic surgeryFranco Valenza
Universita degli Studi di Milano, Dipartimento di Anestesiologia, Terapia Intensiva e Scienze Dermatologiche, Via Festa del Perdono n 7, Milano, Italy
Best Pract Res Clin Anaesthesiol 24:227-41. 2010..Ventilatory and non-ventilatory strategies to protect the lung are discussed...- Do recruitment maneuvers simply improve oxygenation?Franco Valenza
Universita degli Studi di Milano, Fondazione IRCCS Policlinico Ca Granda, Via F, Sforza 35, 20122 Milano, Italy
Crit Care 14:173. 2010..When a recruitment maneuver is performed, the patho-physiological consequences of lung recruitment should guide clinicians more than oxygenation improvement alone... - Prevalence of endotoxemia after surgery and its association with ICU length of stayFranco Valenza
Dipartimento di Anestesia, Rianimazione Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, 20122 Milano, Italy
Crit Care 13:R102. 2009..The aim of this observational study was to investigate the prevalence of endotoxemia after surgery and its association with ICU length of stay... - Effects of the beach chair position, positive end-expiratory pressure, and pneumoperitoneum on respiratory function in morbidly obese patients during anesthesia and paralysisFranco Valenza
Istituto di Anestesia e Rianimazione, Fondazione Ospedale Maggiore, Mangiagalli e Regina Elena IRCCS, Milan, Italy
Anesthesiology 107:725-32. 2007..The authors studied the effects of the beach chair (BC) position, 10 cm H2O positive end-expiratory pressure (PEEP), and pneumoperitoneum on respiratory function in morbidly obese patients undergoing laparoscopic gastric banding... - The consumption of glucose during ex vivo lung perfusion correlates with lung edemaF Valenza
Dipartimento di Anestesia, Terapia Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Transplant Proc 43:993-6. 2011..Ex vivo lung perfusion (EVLP) has been recently proposed to recondition organs before transplantation from donors with marginal or unacceptable features. The aim of our investigation was to explore glucose consumption during EVLP... 
Lactate as a marker of energy failure in critically ill patients: hypothesisFranco Valenza
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena Fondazione IRCCS di Natura Pubblica, Milan, Italy
Crit Care 9:588-93. 2005..Conversely, once the mitochondria are deranged, energy failure occurs even in the presence of normoxia. The lactate increase in critically ill patients may therefore be viewed as an early marker of a potentially reversible state...- Prone position delays the progression of ventilator-induced lung injury in rats: does lung strain distribution play a role?Franco Valenza
Universita degli Studi di Milano, Istituto di Anestesia e Rianimazione, Ospedale Maggiore di Milano IRCCS, Via F Sforza 35, 20122 Milano, Italy
Crit Care Med 33:361-7. 2005..To investigate if prone position delays the progression of experimental ventilator-induced lung injury, possibly due to a more homogeneous distribution of strain within lung parenchyma... - Effects of continuous negative extra-abdominal pressure on cardiorespiratory function during abdominal hypertension: an experimental studyFranco Valenza
Istituto di Anestesia e Rianimazione, Ospedale Maggiore di Milano-Istituto di Ricovero e Cura a Carattere Scientifico, , Via F. Sforza 35, 20122 Milan, Italy
Intensive Care Med 31:105-11. 2005..067+/-0.023 to 0.056+/-0.021 cmH(2)O/ml). CONCLUSIONS: NEXAP increases lung volume and causes a shift of blood from the intrathoracic compartment. It needs to be tailored against abdominal pressure to be effective... - Lung stress and strain during mechanical ventilation for acute respiratory distress syndromeDavide Chiumello
Dipartimento di Anestesia, Rianimazione, Intensiva e Subintensivae, Terapia del Dolore, Fondazione IRCCS, Ospedale Maggiore Policlinico Mangiagalli Regina Elena di Milano, Milan, Italy
Am J Respir Crit Care Med 178:346-55. 2008..Lung injury caused by a ventilator results from nonphysiologic lung stress (transpulmonary pressure) and strain (inflated volume to functional residual capacity ratio)... - Positive end-expiratory pressure delays the progression of lung injury during ventilator strategies involving high airway pressure and lung overdistentionFranco Valenza
Istituto di Anestesia e Rianimazione, Ospedale Maggiore di Milano, Italy
Crit Care Med 31:1993-8. 2003..001). CONCLUSION: These findings confirm that PEEP is protective against ventilator-induced lung injury and may enable the clinician to "buy time" in the progression of lung injury... - Intra-abdominal pressure may be decreased non-invasively by continuous negative extra-abdominal pressure (NEXAP)Franco Valenza
Istituto di Anestesia e Rianimazione, Ospedale Maggiore di Milano-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS, , Via F. Sforza 35, 20122, Milan, Italy
Intensive Care Med 29:2063-7. 2003..When measured, cardiac output did not significantly change with NEXAP. CONCLUSIONS: Negative extra-abdominal pressure may be applied in critically ill patients to decrease intra-abdominal pressure non-invasively... - Static and dynamic components of esophageal and central venous pressure during intra-abdominal hypertensionFranco Valenza
Istituto di Anestesia e Rianimazione, Fondazione Policlinico Ospedale Maggiore, Mangiagalli e Regina Elena IRCCS, Milano, Italy
Crit Care Med 35:1575-81. 2007..To investigate the effects of intra-abdominal hypertension on esophageal and central venous pressure considering values obtained at end-expiration (i.e., in static conditions) and during tidal volume delivery (i.e., in dynamic conditions)... - Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndromeLuciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico, Milan, Italy
Crit Care Med 31:2727-33. 2003..To determine whether gas exchange improvement in response to the prone position is associated with an improved outcome in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS)... - Acute respiratory distress syndrome, the critical care paradigm: what we learned and what we forgotLuciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico IRCCS, Milano, Italy
Curr Opin Crit Care 10:272-8. 2004..Measurements of variables as transpulmonary pressure and end expiratory lung volume, for a rational setting of mechanical ventilation, should be introduced in routine clinical practice... - The role of CT-scan studies for the diagnosis and therapy of acute respiratory distress syndromeLuciano Gattinoni
Istituto di Anestesiologia e Rianimazione, Dipartimento di Anestesia, Rianimazione, e Terapia del Dolore, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli, Universita degli Studi di Milano, Milano, Italy
Clin Chest Med 27:559-70; abstract vii. 2006..CT assessment of lung recruitability seems to be a prerequisite for a rational setting of positive end-expiratory pressure... - Pulmonary computed tomography and adult respiratory distress syndromeLuciano Gattinoni
Istituto de Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico IRCCS, Italy
Swiss Med Wkly 135:169-74. 2005..In this brief review we will emphasize the most relevant new knowledge achieved using CT scanning and we will briefly discuss its clinical use in ARDS patients... - Bench-to-bedside review: chest wall elastance in acute lung injury/acute respiratory distress syndrome patientsLuciano Gattinoni
Institute of Anesthesia and Critical Care, University of Milan, Policlinico IRCCS Hospital, Milan, Italy
Crit Care 8:350-5. 2004..It is always important in the most critically ill patients to assess the intra-abdominal pressure and the chest wall elastance... - Equal increases in respiratory system elastance reflect similar lung damage in experimental ventilator-induced lung injurySilvio Sibilla
Istituto di Anestesia e Rianimazione, Ospedale Maggiore di Milano, IRCCS, Via F Sforza n 35, 20122 Milan, Italy
Intensive Care Med 28:196-203. 2002..We hypothesized that a 50% increase in respiratory system elastance (Ers) would indicate similar degree of lung damage (equi-damage, ED), independently of ventilation strategy...