D Vaira

Summary

Affiliation: University of Bologna
Country: Italy

Publications

  1. ncbi request reprint Review article: Helicobacter pylori infection from pathogenesis to treatment--a critical reappraisal
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Aliment Pharmacol Ther 16:105-13. 2002
  2. ncbi request reprint Routes of transmission of Helicobacter pylori infection
    D Vaira
    First Medical Clinic, University of Bologna, S Orsola Hospital, Bologna, Italy
    Ital J Gastroenterol Hepatol 30:S279-85. 1998
  3. ncbi request reprint Noninvasive tests to diagnose Helicobacter pylori infection
    Luigi Gatta
    Department of Internal Medicine and Gastroenterology, Nuove Patologie, Via Massarenti 9, 40138, Bologna, Italy
    Curr Gastroenterol Rep 5:351-2. 2003
  4. ncbi request reprint Peptic ulcer and Helicobacter pylori: update on testing and treatment
    Dino Vaira
    University of Bologna S Orsola Malpighi Hospital, Italy
    Postgrad Med 117:17-22, 46. 2005
  5. ncbi request reprint Stool test for Helicobacter pylori
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Hospital, 40138 Bologna, Italy
    Dig Liver Dis 36:446-7. 2004
  6. ncbi request reprint [Non-invasive analyses for the diagnosis of Helicobacter pylori infection. A critical review of the literature]
    Dino Vaira
    Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi, Policlinico S Orsola Malpighi di Bologna
    Ann Ital Med Int 20:23-7. 2005
  7. ncbi request reprint Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial
    Dino Vaira
    University of Bologna, Bologna, Italy
    Ann Intern Med 146:556-63. 2007
  8. ncbi request reprint How to proceed in Helicobacter pylori-positive chronic gastritis refractory to first- and second-line eradication therapy
    Dino Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Dig Dis 25:203-5. 2007
  9. ncbi request reprint Review article: diagnosis of Helicobacter pylori infection
    D Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, Nuove Patologie, Bologna, Italy
    Aliment Pharmacol Ther 16:16-23. 2002
  10. ncbi request reprint The stool antigen test for detection of Helicobacter pylori after eradication therapy
    Dino Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Ann Intern Med 136:280-7. 2002

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Review article: Helicobacter pylori infection from pathogenesis to treatment--a critical reappraisal
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Aliment Pharmacol Ther 16:105-13. 2002
    ..pylori to gastro-oesophageal reflux disease; infection in the very young and very old; diagnostic techniques; and management of H. pylori infections with particular emphasis on eradication regimens and antibiotic resistance...
  2. ncbi request reprint Routes of transmission of Helicobacter pylori infection
    D Vaira
    First Medical Clinic, University of Bologna, S Orsola Hospital, Bologna, Italy
    Ital J Gastroenterol Hepatol 30:S279-85. 1998
    ..The mode of transmission of Helicobacter pylori, as is yet, not known. Available information support the hypothesis of spread through close personal contact, considering humans as the only significant reservoir of infection...
  3. ncbi request reprint Noninvasive tests to diagnose Helicobacter pylori infection
    Luigi Gatta
    Department of Internal Medicine and Gastroenterology, Nuove Patologie, Via Massarenti 9, 40138, Bologna, Italy
    Curr Gastroenterol Rep 5:351-2. 2003
  4. ncbi request reprint Peptic ulcer and Helicobacter pylori: update on testing and treatment
    Dino Vaira
    University of Bologna S Orsola Malpighi Hospital, Italy
    Postgrad Med 117:17-22, 46. 2005
    ..In this article, the authors discuss the association between H pylori and peptic ulcer disease, the available tests for detecting the infection, and the latest treatment strategies for effective eradication...
  5. ncbi request reprint Stool test for Helicobacter pylori
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Hospital, 40138 Bologna, Italy
    Dig Liver Dis 36:446-7. 2004
  6. ncbi request reprint [Non-invasive analyses for the diagnosis of Helicobacter pylori infection. A critical review of the literature]
    Dino Vaira
    Dipartimento di Medicina Interna e Gastroenterologia, Universita degli Studi, Policlinico S Orsola Malpighi di Bologna
    Ann Ital Med Int 20:23-7. 2005
    ..The available non-invasive tests are reviewed in this article...
  7. ncbi request reprint Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial
    Dino Vaira
    University of Bologna, Bologna, Italy
    Ann Intern Med 146:556-63. 2007
    ..Antimicrobial resistance has decreased eradication rates for Helicobacter pylori infection worldwide...
  8. ncbi request reprint How to proceed in Helicobacter pylori-positive chronic gastritis refractory to first- and second-line eradication therapy
    Dino Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Dig Dis 25:203-5. 2007
    ..A third-line treatment with rifabutin-based regimen has been proposed...
  9. ncbi request reprint Review article: diagnosis of Helicobacter pylori infection
    D Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, Nuove Patologie, Bologna, Italy
    Aliment Pharmacol Ther 16:16-23. 2002
    ..Indeed, a number of clinical guidelines recommend noninvasive testing followed by treatment of H. pylori for dyspeptic patients in primary care based on clinical and economic analyses...
  10. ncbi request reprint The stool antigen test for detection of Helicobacter pylori after eradication therapy
    Dino Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, Via Massarenti 9, 40138 Bologna, Italy
    Ann Intern Med 136:280-7. 2002
    ..Current noninvasive tests to confirm the eradication of Helicobacter pylori must be performed 4 weeks or more after eradication therapy is completed...
  11. ncbi request reprint Diagnosis of Helicobacter pylori infection with a new non-invasive antigen-based assay. HpSA European study group
    D Vaira
    Clinica Medica I, Universita di Bologna, Italy
    Lancet 354:30-3. 1999
    ..Helicobacter pylori is a common human pathogen implicated in certain gastrointestinal diseases. In the search for new non-invasive techniques to diagnose H. pylori infection, we evaluated an EIA for H. pylori antigen in stool (HpSA)...
  12. ncbi request reprint Review article:invasive and non-invasive tests for Helicobacter pylori infection
    D Vaira
    Ist Medical Clinic, University of Bologna, Italy
    Aliment Pharmacol Ther 14:13-22. 2000
    ..pylori, and a combination of two is recommended if this is feasible. The choice of the test to be used is not straightforward and may vary according to the clinical condition and local expertise...
  13. ncbi request reprint Accurate diagnosis of Helicobacter pylori. Stool tests
    D Vaira
    Department of Internal Medicine, University of Bologna, Bologna, Italy
    Gastroenterol Clin North Am 29:917-23. 2000
    ..pylori stool assay has the potential to become the preferred diagnostic tool in many different clinical settings from epidemiologic studies to pediatric investigations, from pre-endoscopic screening policies to posttherapy monitoring...
  14. ncbi request reprint [Treatment for Helicobacter pylori: current criteria]
    Dino Vaira
    Dipartimento di Medicina Interna e Gastroenterologia, Universita, Bologna
    Recenti Prog Med 98:574-82; quiz 602. 2007
    ....
  15. ncbi request reprint How valuable is the application on consensus guidelines in the management of functional gastrointestinal disorders?
    D Vaira
    1st Medical Clinic, S Orsola Hospital, Nuove Patologie, University of Bologna, Via Massarenti 9, I 40138 Bologna, Italy
    Dig Dis 19:225-31. 2001
    ..Symptoms have in common disturbances in sensory and/or motor gastrointestinal function, which sometimes may overlap across anatomic regions. Nevertheless, several studies provide evidence for site-specific syndromes...
  16. ncbi request reprint Helicobacter pylori: diseases, tests and treatment
    U Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, University of Bologna, Italy
    Dig Liver Dis 33:788-94. 2001
    ..The challenge of Helicobacter pylori eradication is not very easy to obtain. The possible scenario and the use of a new proton pump inhibitor (esomeprazole) are reviewed and discussed...
  17. pmc Effect of Helicobacter pylori eradication on development of dyspeptic and reflux disease in healthy asymptomatic subjects
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Gut 52:1543-7. 2003
    ..The aim of this study was to assess the effect of eradication therapy on the development of dyspeptic and gastro-oesophageal reflux disease in a cohort of asymptomatic individuals observed over a prolonged period...
  18. ncbi request reprint The clinical role of cytochrome p450 genotypes in Helicobacter pylori management
    A Sapone
    Department of Pharmacology, Pharmacogenomic Unit St Orsola Hospital, University of Bologna, Bologna, Italy
    Am J Gastroenterol 98:1010-5. 2003
    ..The aim of this pharmacogenomics study was to investigate the influence of different cytochrome P450 (CYP) genotypes in Helicobacter pylori eradication therapy...
  19. ncbi request reprint Best cut-off values for [14C]-urea breath tests for Helicobacter pylori detection
    L Gatta
    Dept of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Hospital, Bologna, Italy
    Scand J Gastroenterol 38:1144-8. 2003
    ....
  20. ncbi request reprint Review article: the transmission of Helicobacter pylori from stomach to stomach
    D Vaira
    Department of Internal Medicine, Nuove Patologie, St Orsola Hospital, University of Bologna, Via Massarenti 9 40138 Bologna, Italy
    Aliment Pharmacol Ther 15:33-42. 2001
    ..Evidence suggests close personal contact is important and that acquisition occurs mainly in childhood. This article reviews the evidence for the source of infection and the route of transmission of H. pylori...
  21. ncbi request reprint A rapid immunochromatographic assay for Helicobacter pylori in stool before and after treatment
    L Gatta
    Department of Internal Medicine and Gastroenterology, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 20:469-74. 2004
    ..Current guidelines recommend non-invasive testing and treatment of young dyspeptic patients without alarm symptoms...
  22. ncbi request reprint A 10-day levofloxacin-based triple therapy in patients who have failed two eradication courses
    L Gatta
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 22:45-9. 2005
    ..A standard third-line treatment is lacking, and European guidelines recommend performing culture in these patients. However, the use of this procedure as 'routine practice' is definitively not feasible...
  23. ncbi request reprint Levofloxacin-based triple therapy for Helicobacter pylori re-treatment: role of bacterial resistance
    F Perna
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Dig Liver Dis 39:1001-5. 2007
    ..This study aimed to assess the efficacy of a levofloxacin-amoxycillin triple therapy as a second-line treatment, and the role of primary levofloxacin resistance...
  24. pmc Accuracy of breath tests using low doses of 13C-urea to diagnose Helicobacter pylori infection: a randomised controlled trial
    L Gatta
    Department of Internal Medicine and Gastroenterology, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Gut 55:457-62. 2006
    ..Since its first description, the method has been extensively modified. However, only the dose of 13C-urea and the measurement equipment are directly related to the cost of the test...
  25. doi request reprint Accuracy of a new ultrafast rapid urease test to diagnose Helicobacter pylori infection in 1000 consecutive dyspeptic patients
    D Vaira
    Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
    Aliment Pharmacol Ther 31:331-8. 2010
    ..Rapid diagnostic tools for Helicobacter pylori are important in endoscopy...
  26. ncbi request reprint Diagnostic accuracy of a new rapid urease test (Pronto Dry), before and after treatment of Helicobacter pylori infection
    F Perna
    Department of Internal Medicine and Gastroenterology, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Minerva Gastroenterol Dietol 51:247-54. 2005
    ..Aim of the study was to evaluate the diagnostic accuracy and the reaction time of Pronto Dry vs liquid phase-rapid urease test, before and after treatment of Helicobacter pylori infections...
  27. ncbi request reprint A rapid, low-dose, 13C-urea tablet for the detection of Helicobacter pylori infection before and after treatment
    L Gatta
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 17:793-8. 2003
    ..A new urea breath test (UBT) has been described which uses a tablet formulation of 13C-urea with citric acid and allows breath sampling to be performed as early as 10 min after ingestion of the tablet...
  28. ncbi request reprint Effect of proton pump inhibitors and antacid therapy on 13C urea breath tests and stool test for Helicobacter pylori infection
    Luigi Gatta
    Department of Internal Medicine and Gastroenterology, University of Bologna, S Orsola Halpighi Hospital, Bologna, Italy
    Am J Gastroenterol 99:823-9. 2004
    ....
  29. ncbi request reprint Non-invasive techniques for the diagnosis of Helicobacter pylori infection
    L Gatta
    Department of Internal Medicine and Gastroenterology, Nuove Patologie, Bologna, Italy
    Clin Microbiol Infect 9:489-96. 2003
    ..Nevertheless, two non-invasive tests are commonly used: the urea breath test, and the stool antigen test...
  30. ncbi request reprint Meta-analysis: the efficacy of proton pump inhibitors for laryngeal symptoms attributed to gastro-oesophageal reflux disease
    L Gatta
    Department of Internal Medicine and Gastroenterology, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Aliment Pharmacol Ther 25:385-92. 2007
    ..Many investigators have proposed an association between gastro-oesophageal reflux disease and laryngo-pharyngeal symptoms, suggesting that medical or surgical therapy for reflux may be useful...
  31. doi request reprint A comparison amongst three rapid urease tests to diagnose Helicobacter pylori infection in 375 consecutive dyspeptic
    Dino Vaira
    Department of Internal Medicine and Gastroenterology, S Orsola Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Intern Emerg Med 5:41-7. 2010
    ..Reading the test results at 1 min may increase false-negative results with decreasing sensitivity...
  32. ncbi request reprint Susceptibility of Helicobacter pylori to metronidazole
    Federico Perna
    Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy
    Am J Gastroenterol 98:2157-61. 2003
    ..pylori to metronidazole; and 2) to investigate whether potential discrepancies could be caused by the simultaneous presence of metronidazole susceptible and metronidazole resistant bacterial subpopulations...
  33. ncbi request reprint Growth and adult height in atypical coeliac patients, with or without growth hormone deficiency
    Silvana Salardi
    Department of Pediatrics, University of Bologna, Bologna, Italy
    J Pediatr Endocrinol Metab 18:769-75. 2005
    ..To evaluate the effect of a gluten-free diet on growth and adult height, when available, in coeliac children without gastrointestinal symptoms...
  34. ncbi request reprint Antimicrobial activity of esomeprazole versus omeprazole against Helicobacter pylori
    Luigi Gatta
    Department of Internal Medicine and Gastroenterology, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    J Antimicrob Chemother 51:439-42. 2003
    ..As proton pump inhibitors also exert an antibacterial activity, we aimed to compare esomeprazole and omeprazole for their antimicrobial activity against Helicobacter pylori in vitro...
  35. ncbi request reprint Serological markers for gastric atrophy in asymptomatic patients infected with Helicobacter pylori
    Chiara Ricci
    Department of Internal Medicine and Gastroenterology, University of Bologna, University Hospital S Orsola Malpighi, Bologna, Italy
    Am J Gastroenterol 99:1910-5. 2004
    ..pylori) infection. This blinded, controlled study was designed to determine if serum gastrin and pepsinogens were reliable markers of atrophy in asymptomatic patients...
  36. doi request reprint Efficacy of 5-ASA in the treatment of colonic diverticular disease
    Luigi Gatta
    Versilia Hospital, Lido di Camaiore, Department of Clinical Science, University of Parma, S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    J Clin Gastroenterol 44:113-9. 2010
    ..To assess the therapeutic efficacy of 5-aminosalicylic acid (5-ASA) in patients with colonic diverticular disease performing a systematic review of the literature...
  37. ncbi request reprint Helicobacter pylori: current status and future prospects
    Rachel O'Mahony
    Centre for Infectious Diseases and International Health, RF and UCL Medical School, UK
    Sci Prog 87:269-96. 2004
    ....
  38. ncbi request reprint Update on the treatment of patients with Helicobacter pylori
    Angelo Zullo
    Am Fam Physician 76:633. 2007
  39. ncbi request reprint Non-invasive tests for the diagnosis of H. pylori infection
    Nimish Vakil
    University of Wisconsin Medical School, Milwaukee, Wisconsin, USA
    Rev Gastroenterol Disord 4:1-6. 2004
    ..The choice of an appropriate test depends on the pre-test probability of infection, the characteristics of the test being used, and the cost-effectiveness of the test. This article reviews available non-invasive tests...
  40. ncbi request reprint Sequential therapy for Helicobacter pylori: time to consider making the switch?
    Nimish Vakil
    University of Wisconsin School of Medicine and Public Health, Madison
    JAMA 300:1346-7. 2008
  41. ncbi request reprint Errors in a meta-analysis of treatments for Helicobacter pylori infection
    Luigi Gatta
    Ann Intern Med 149:686; author reply 686. 2008
  42. ncbi request reprint Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis
    Gerardo Nardone
    Department of Clinical and Experimental Medicine, Gastroenterology Unit, University Federico II, Naples, Italy
    J Pathol 202:305-12. 2004
    ..In conclusion, H pylori-dependent induction of COX-2 and mPGES1 is associated with enhanced production of P-gp and Bcl-xL that may contribute to gastric tumourigenesis and resistance to therapy...
  43. ncbi request reprint Helicobacter: a paradigm shift in peptic ulcer disease and more?
    Christelle Basset
    Royal Free and University College London Medical School, Windeyer Institute of Medical Sciences
    Sci Prog 85:13-31. 2002
    ..This is a major shift in medical practice. Continued investigations on Helicobacter pylori are bringing to light other possible associations with disease as well as delineating plausible biological mechanisms for disease pathogenesis...
  44. ncbi request reprint 13C-urea breath test values and Helicobacter pylori eradication
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Via E Morosini, 30, Rome 00153, Italy
    Dig Dis Sci 53:370-4. 2008
    ..This large analysis failed to demonstrate a role for DOB value in H. pylori eradication with either a 10-day triple or sequential therapy...
  45. pmc The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis
    Angelo Zullo
    Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, Rome, Italy
    Gut 56:1353-7. 2007
    ..However, a critical fall in the H pylori eradication rate following these therapies has been observed in the last few years. The sequential regimen is a novel, promising therapeutic approach...
  46. ncbi request reprint Helicobacter pylori antigen stool test and 13C-urea breath test in patients after eradication treatments
    Francesco Perri
    Division of Gastroenterology, Casa Sollievo della Sofferenza Hospital, Istituto di Ricovero e Cuva a Cavattere Scientifico, San Giovanni Rotondo, Italy
    Am J Gastroenterol 97:2756-62. 2002
    ..pylori infection. The aim of this study was to evaluate the agreement between the two tests in patients after treatment...
  47. ncbi request reprint Are Helicobacter species and enterotoxigenic Bacteroides fragilis involved in inflammatory bowel disease?
    Christelle Basset
    Centre for Infectious Diseases and International Health, Windeyer Institute of Medical Sciences, Royal Free and University College London Medical School, The Windeyer Building, 46 Cleveland Street, London WIT 4JF, United Kingdom
    Dig Dis Sci 49:1425-32. 2004
    ..In conclusion, Helicobacter was not associated with IBD in our population of patients, although ETBF may be associated with active disease...
  48. ncbi request reprint CagA and VacA are immunoblot markers of past Helicobacter pylori infection in atrophic body gastritis
    Bruno Annibale
    Department of Digestive and Liver Disease, University La Sapienza, Ospedale Sant Andrea, Rome, Italy
    Helicobacter 12:23-30. 2007
    ..pylori infection is detectable. We aimed to investigate whether patients with ABG, classified as H. pylori-negative by conventional methods (ELISA serology and Giemsa stain histology), have been previously exposed to the infection...
  49. ncbi request reprint Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori
    Rachel O'Mahony
    Centre for Infectious Diseases and International Health, Royal Free and University College London Medical School, Windeyer Building, 46 Cleveland Street, London, W1P 6DB, United Kingdom
    World J Gastroenterol 11:7499-507. 2005
    ..To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori (H. pylori)...
  50. ncbi request reprint Role of noninvasive tests (C-urea breath test and stool antigen test) as additional tools in diagnosis of Helicobacter pylori infection in patients with atrophic body gastritis
    Edith Lahner
    Digestive and Liver Disease Unit, II Medical School, University La Sapienza, Rome, Italy
    Helicobacter 9:436-42. 2004
    ..Detection of Helicobacter pylori infection in atrophic body gastritis (ABG) is difficult, as during progression of body atrophy, H. pylori disappears...
  51. ncbi request reprint Diagnosis of Helicobacter pylori: invasive and non-invasive tests
    Chiara Ricci
    Gastroenterology Unit, University of Brescia, Italy
    Best Pract Res Clin Gastroenterol 21:299-313. 2007
    ..The choice of appropriate test depends on the pre-test probability of infection, the characteristics of the test being used and its cost-effectiveness...
  52. ncbi request reprint Helicobacter pylori and pancreatic disease
    Gianpiero Manes
    JOP 4:111-6. 2003
  53. ncbi request reprint Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy
    Rachel O'Mahony
    Centre for Infectious Diseases and International Health, Royal Free and University College London Medical School, The Windeyer Building, 46 Cleveland Street, London W1T 4JF, UK
    J Microbiol Methods 61:105-26. 2005
    ..The method can be applied to organisms ranging in size from small bacteria to larger yeast cells...