Research Topics
| A UngarSummaryAffiliation: University of Florence Country: Italy Publications
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Publications
Two-year morbidity and mortality in elderly patients with syncopeAndrea Ungar
Unit of Gerontology and Geriatric Medicine, Department of Critical Care Medicine and Surgery, University of Florence, Italy
Age Ageing 40:696-702. 2011..syncope is a common cause of hospitalisation in the elderly. However, morbidity and mortality in elderly patients with syncope is not well established...
Isolated ambulatory hypertension is common in outpatients referred to a hypertension centreA Ungar
Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics Hypertension Centre, University of Florence, and Azienda Ospedaliera Careggi, Florence, Italy
J Hum Hypertens 18:897-903. 2004..These findings suggest that isolated ambulatory hypertension is very common and probably the indications for ABPM should be more extensive in outpatients referred to hypertensive centre...
Diagnosis and characteristics of syncope in older patients referred to geriatric departmentsAndrea Ungar
Unit of Gerontology and Geriatric Medicine, Department of Critical Care Medicine and Surgery, University of Florence, and Division of Cardiology, Ospedale San Pietro Igneo, Florence, Italy
J Am Geriatr Soc 54:1531-6. 2006..To test the applicability and safety of a standardized diagnostic algorithm in geriatric departments and to define the prevalence of different causes of syncope in older patients...
Low diastolic ambulatory blood pressure is associated with greater all-cause mortality in older patients with hypertensionAndrea Ungar
University of Florence, Italy
J Am Geriatr Soc 57:291-6. 2009..To assess the relationship between office and ambulatory systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP) and total mortality in elderly patients with hypertension...
[Evaluation of "complex syncope: what are the indications for second-level investigations?]Andrea Ungar
Centro per lo Studio della Sincope, Cardiologia e Medicina Geriatrica, Universita degli Studi, Azienda Ospedaliero Universitaria Careggi, Firenze rdiologia, Azienda USL 11, Empoli FI
G Ital Cardiol (Rome) 10:6-17. 2009..The role of Syncope Units in the management of patients with temporary loss of consciousness is also described...
Changes in renal autacoids and hemodynamics associated with aging and isolated systolic hypertensionA Ungar
Istituto di Gerontologia e Geriatria, Università degli Studi di Firenze e Azienda Ospedaliera Careggi, Firenze, Italy
Prostaglandins Other Lipid Mediat 62:117-33. 2000..Further studies will elucidate whether antihypertensive treatment per se, or specific classes of antihypertensive drugs, are able to revert this impairment...
The management of syncope in older adultsA Ungar
Syncope Unit, Unit of Cardiology and Geriatric Medicine, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
Minerva Med 100:247-58. 2009..There are no consistent differences in the treatment of syncope between older and younger population, but a specific approach is necessary for orthostatic hypotension, drug therapy and pacemaker implantation...
Early and late outcome of treated patients referred for syncope to emergency department: the EGSYS 2 follow-up studyAndrea Ungar
Unit of Geriatric Cardiology and Medicine, Department of Critical Care Medicine and Surgery, University of Florence, Viale Pieraccini 6, 50141 Florence, Italy
Eur Heart J 31:2021-6. 2010..Patients were enrolled in the Evaluation of Guidelines in SYncope Study 2 (EGSYS 2) study. The guidelines of the European Society of Cardiology were strictly followed in the management of patients...
Calcium channel blockers and nephroprotectionAndrea Ungar
Unit of Gerontology and Geriatric Medicine, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
Aging Clin Exp Res 17:31-9. 2005..This paper reviews the main pathophysiological aspects of renal damage in hypertension, the effects of various types of calcium channel blockers (CCBs) on renal function, and their role in nephroprotection...
Impaired renal adaptation to stress in the elderly with isolated systolic hypertensionS Castellani
Istituto di Clinica Medica Generale e Cardiologia, Firenze, Italy
Hypertension 34:1106-11. 1999..This hemodynamic pattern may predispose ISH patients to a higher risk of renal injury...
Changes in renal autacoids in aged human hypertensivesA Ungar
Dipartimento di Area Critica Medico Chirurgica, Università degli Studi di Firenze e Azienda Ospedaliera Careggi, Italy
J Physiol Pharmacol 51:619-30. 2000..These aspects underline the primary role of the antihypertensive treatment of isolated systolic hypertension, not only for the prevention of cardiovascular mortality but also of renal damage and/or end-stage renal disease...
Renal adaptive mechanisms in aged and hypertensive humans: possible effects of treatmentC Di Serio
Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics, University of Florence, Azienda Ospedaliera Careggi, Florence, Italy
Med Sci Monit 7:1203-11. 2001..CONCLUSIONS: Further studies are needed to confirm the nephroprotective effects of these drugs, particularly of ACE-inhibitors. These data may be a pathophysiological basis for future clinical trials...
Undertreatment of hypertension in community-dwelling older adults: a drug-utilization study in Dicomano, ItalyM Di Bari
Department of Gerontology and Geriatrics, University of Florence, Italy
J Hypertens 17:1633-40. 1999..To define: (1) the prevalence of and (2) factors associated with undertreatment of hypertension in older persons; and (3) the prevalence of specific drug regimens and reasons for their selection...
Metabolic syndrome and pulse pressureE Mannucci
Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics, University of Florence, Florence, Italy
Diabetes Obes Metab 9:600-2. 2007..Aim of the present study is to verify the association of high PP with metabolic syndrome (MS) and with its individual components...
Abnormal pressure passive dilatation of cerebral arterioles in the elderly with isolated systolic hypertensionSergio Castellani
Institute of Internal Medicine and Cardiology, Department of Critical Care Medicine and Surgery, University of Florence, and Azienda Ospedaliera Universitaria Careggi, Florence, Italy
Hypertension 48:1143-50. 2006..This event can amplify the pressure insult on cerebral hemodynamics and increase the predisposition to cerebral damage, such as vascular cognitive impairment or stroke...
Usefulness and safety of shortened head-up tilt testing potentiated with sublingual glyceryl trinitrate in older patients with recurrent unexplained syncopeAttilio Del Rosso
Division of Cardiology, Ospedale San Pietro Igneo, Fucecchio, Florence, Italy
J Am Geriatr Soc 50:1324-8. 2002..CONCLUSION: The shortened GTN-HUT provides satisfactory positivity rate and specificity in older patients. This test may be considered as a diagnostic tool in assessing recurrent unexplained syncope in older patients...
Hypertension and reduced renal function in an 83-year-old patientAndrea Ungar
Unit of Geriatric Cardiology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
Intern Emerg Med 1:40-8. 2006
Prognostic stratification of older persons based on simple administrative data: development and validation of the "Silver Code," to be used in emergency department triageMauro Di Bari
Department of Critical Care Medicine, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero Universitaria Careggi, Via delle Oblate 4, Florence, Italy
J Gerontol A Biol Sci Med Sci 65:159-64. 2010..Whether such targeting can be performed through simple administrative data is unknown...
Epidemiology of suboptimal prescribing in older, community dwellers: a two-wave, population-based survey in Dicomano, ItalyFrancesco Lapi
Tuscan Regional Centre of Pharmacovigilance, Department of Pharmacology, University of Florence, Florence, Italy
Drugs Aging 26:1029-38. 2009..Time trends of suboptimal prescribing in older, community dwellers have been poorly investigated, particularly in Italy...
Pulse pressure and mortality in hypertensive type 2 diabetic patients. A cohort studyEdoardo Mannucci
Geriatric Unit, Department of Critical Care, University of Florence Medical School, Florence, Italy
Diabetes Metab Res Rev 22:172-5. 2006..An association between office PP and cardiovascular mortality has been previously reported in diabetic patients, while the relationship between ambulatory measurements of PP and all-cause mortality has not been assessed so far...
Alfuzosin (10 mg) does not affect blood pressure in young healthy menNicola Mondaini
Urology Division, S Maria Annunziata Hospital, University of Florence, Florence, Italy
Eur Urol 50:1292-6; discussion 1297-8. 2006..The objective of this study was to evaluate the effect of 10mg alfuzosin on blood pressure (BP) and heart rate (HR) in young healthy volunteers...
Methodology of head-up tilt testing potentiated with sublingual nitroglycerin in unexplained syncopeA Del Rosso
Cardiology Division, Ospedale San Pietro Igneo, Fucecchio, Italy
Am J Cardiol 85:1007-11. 2000..Moreover, the shortened test provided a high specificity and adequate reproducibility for both the positive and the negative responses...
Renal, but not systemic, hemodynamic effects of dopamine are influenced by the severity of congestive heart failureAndrea Ungar
Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliera Careggi, Florence, Italy
Crit Care Med 32:1125-9. 2004..A greater clinical severity of congestive heart failure impairs the renal effects of dopamine, probably through a selective loss in renal vasodilating capacity...
Is the third component of metabolic syndrome really predictive of outcomes in type 2 diabetic patients?Matteo Monami
Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics, University of Florence and Azienda Ospedaliera Careggi, Via delle Oblate 4, 50134 Florence, Italy
Diabetes Care 29:2515-7. 2006
Multidisciplinary approach to "accidental" falls in the elderly: a case reportGianluigi Galizia
Division of Geriatrics, Department of Clinical Medicine Cardiovascular and Immunological Science University of Naples Federico II, Naples, Italy
Geriatr Gerontol Int 8:130-2. 2008..Differential diagnosis between "accidental" and "apparently accidental" falls in elderly patients is very difficult but a multidisciplinary geriatric evaluation can clarify the correct diagnosis...
Standardized-care pathway vs. usual management of syncope patients presenting as emergencies at general hospitalsMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
Europace 8:644-50. 2006..The study hypothesis was that a decision-making approach improves diagnostic yield and reduces resource consumption for patients with syncope who present as emergencies at general hospitals...
Guidelines on management (diagnosis and treatment) of syncope--update 2004Michele Brignole
Europace 6:467-537. 2004
A new management of syncope: prospective systematic guideline-based evaluation of patients referred urgently to general hospitalsMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
Eur Heart J 27:76-82. 2006..The guidelines of the European Society of Cardiology (ESC) define the current standard for the management of syncope, but are still incompletely applied in the clinical setting...
[Guidelines on management (diagnosis and treatment) of syncope. Update 2004. Executive summary]Michele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
Rev Esp Cardiol 58:175-93. 2005
Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive SummaryMichele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
Eur Heart J 25:2054-72. 2004
