Giovanni Tulipano

Summary

Affiliation: University of Brescia
Country: Italy

Publications

  1. ncbi request reprint Novel insights in somatostatin receptor physiology
    Giovanni Tulipano
    Division of Experimental Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Eur J Endocrinol 156:S3-11. 2007
  2. doi request reprint Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells
    Giovanni Tulipano
    Pharmacology Unit, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Italy
    Mol Cell Endocrinol 365:197-206. 2013
  3. ncbi request reprint Points of integration between the intracellular energy sensor AMP-activated protein kinase (AMPK) activity and the somatotroph axis function
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, Unit of Pharmacology, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Endocrine 42:292-8. 2012
  4. doi request reprint Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Peptides 32:835-8. 2011
  5. doi request reprint AMP-activated protein kinase regulates normal rat somatotroph cell function and growth of rat pituitary adenomatous cells
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, Unit of Pharmacology, University of Brescia, Viale Europa 11, 25123, Brescia, Italy
    Pituitary 14:242-52. 2011
  6. doi request reprint Direct effects of casein phosphopeptides on growth and differentiation of in vitro cultured osteoblastic cells (MC3T3-E1)
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Italy
    Regul Pept 160:168-74. 2010
  7. doi request reprint Effects of olanzapine on glucose transport, proliferation and survival in C2C12 myoblasts
    Giovanni Tulipano
    Division of Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
    Mol Cell Endocrinol 292:42-9. 2008
  8. ncbi request reprint Glucocorticoid inhibition of growth in rats: partial reversal with the full-length ghrelin analog BIM-28125
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
    Pituitary 10:267-74. 2007
  9. ncbi request reprint The somatostatin subtype-2 receptor antagonist, BIM-23627, improves the catabolic effects induced by long-term glucocorticoid treatment in the rat
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnology, University of Brescia, Italy
    Regul Pept 125:85-92. 2005
  10. doi request reprint Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring
    Daniela Cocchi
    Division of Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy
    Toxicol Appl Pharmacol 237:127-36. 2009

Detail Information

Publications13

  1. ncbi request reprint Novel insights in somatostatin receptor physiology
    Giovanni Tulipano
    Division of Experimental Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Eur J Endocrinol 156:S3-11. 2007
    ..Different somatostatin analogs may induce distinct conformations of the receptor/ligand complex, preferentially coupled to either receptor signaling or receptor endocytosis...
  2. doi request reprint Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells
    Giovanni Tulipano
    Pharmacology Unit, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Italy
    Mol Cell Endocrinol 365:197-206. 2013
    ..Moreover, AICAR and SS-14 reduced ERK phosphorylation with a different time course. The combined treatment reduced phospho-ERK levels at any time point...
  3. ncbi request reprint Points of integration between the intracellular energy sensor AMP-activated protein kinase (AMPK) activity and the somatotroph axis function
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, Unit of Pharmacology, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Endocrine 42:292-8. 2012
    ..Based on the previously summarized contents, the aim of the present work has been to review currently available data suggesting a role of AMPK in the interplay between GH axis activity and metabolic functions...
  4. doi request reprint Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
    Peptides 32:835-8. 2011
    ..We proved that the bioactive peptide Ile-Pro-Ala can be regarded as a moderate DPP-4 inhibitor...
  5. doi request reprint AMP-activated protein kinase regulates normal rat somatotroph cell function and growth of rat pituitary adenomatous cells
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, Unit of Pharmacology, University of Brescia, Viale Europa 11, 25123, Brescia, Italy
    Pituitary 14:242-52. 2011
    ..In conclusion, our studies showed that AMPK has a role in regulating somatotroph function in normal rat pituitary and proliferation of pituitary adenomatous cells...
  6. doi request reprint Direct effects of casein phosphopeptides on growth and differentiation of in vitro cultured osteoblastic cells (MC3T3-E1)
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Italy
    Regul Pept 160:168-74. 2010
    ..Finally, our data may also suggest important clues about the role of intrinsic phosphorylated peptides derived from endogenous phosphorylated proteins in bone metabolism, apart from extrinsic CPPs...
  7. doi request reprint Effects of olanzapine on glucose transport, proliferation and survival in C2C12 myoblasts
    Giovanni Tulipano
    Division of Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
    Mol Cell Endocrinol 292:42-9. 2008
    ..L., Henry, C.R., Bello, N.T., Hajnal, A., Lynch, S.L., Halle, B., Lynch, C.J., 2006. Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obesity 14, 36-50]...
  8. ncbi request reprint Glucocorticoid inhibition of growth in rats: partial reversal with the full-length ghrelin analog BIM-28125
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
    Pituitary 10:267-74. 2007
    ..These preclinical results leads to the conclusion that BIM-28125 may represent a good tool to reverse the catabolic effects induced by glucocorticoids...
  9. ncbi request reprint The somatostatin subtype-2 receptor antagonist, BIM-23627, improves the catabolic effects induced by long-term glucocorticoid treatment in the rat
    Giovanni Tulipano
    Department of Biomedical Sciences and Biotechnology, University of Brescia, Italy
    Regul Pept 125:85-92. 2005
    ..Further studies are required in order to fully optimize the SSTR-2 antagonist-induced reversal of DEX-induced somatic growth inhibition...
  10. doi request reprint Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring
    Daniela Cocchi
    Division of Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy
    Toxicol Appl Pharmacol 237:127-36. 2009
    ..In conclusion, the developmental exposure to the four selected PCB compounds used in the present study induced far-reaching effects in the adult offspring, the male rats appearing more sensitive than females...
  11. ncbi request reprint Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation
    Giovanni Tulipano
    Division of Pharmacology and Toxicology, Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy
    Neuroendocrinology 85:61-70. 2007
    ..To our knowledge, a suitable animal model to investigate how atypical antipsychotics may induce diabetes in patients has not received much attention...
  12. ncbi request reprint Somatostatin receptor 2 is activated in cortical neurons and contributes to neurodegeneration after focal ischemia
    Ralf K Stumm
    Institute of Pharmacology and Toxicology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany
    J Neurosci 24:11404-15. 2004
    ..In summary, we provide direct evidence for activation of SSTR2 by an endogenous ligand after focal ischemia. Activation of functional SSTR2 receptors contributes to increased SSTR2 gene expression and postischemic neurodegeneration...
  13. ncbi request reprint Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes
    Giovanni Tulipano
    Institut fur Pharmakologie und Toxikologie, Otto von Guericke Universitat, Leipziger Strasse 44, 39120 Magdeburg, Germany
    J Biol Chem 279:21374-82. 2004
    ..Together, these findings may provide important clues about the regulation of receptor responsiveness during long-term administration of somatostatin analogs...