Affiliation: University of Chieti
Lanza Cariccio V, Scionti D, Raffa A, Iori R, Pollastro F, Diomede F, et al
. Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway. Int J Mol Sci. 2018;19: pubmed publisher
..In conclusion, hPDLSCs treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential. ..
Trubiani O, Recchioni R, Moroni F, Pizzicannella J, Caputi S, Di Primio R. Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation. J Pineal Res. 2005;39:425-31 pubmed
..Taken together, our study indicates that melatonin may play a role as potential therapeutic drug in specific lymphoproliferative diseases. ..
Trubiani O, Diomede F. Xeno-free culture of human periodontal ligament stem cells. Methods Mol Biol. 2015;1283:87-92 pubmed publisher
Diomede F, D Aurora M, Gugliandolo A, Merciaro I, Orsini T, Gatta V, et al
. Biofunctionalized Scaffold in Bone Tissue Repair. Int J Mol Sci. 2018;19: pubmed publisher
..These results suggest a promising potential application of CM from hPDLSCs and scaffolds for bone defect restoration and in particular for calvarial repair in case of trauma. ..
Diomede F, Gugliandolo A, Cardelli P, Merciaro I, Ettorre V, Traini T, et al
. Three-dimensional printed PLA scaffold and human gingival stem cell-derived extracellular vesicles: a new tool for bone defect repair. Stem Cell Res Ther. 2018;9:104 pubmed publisher
..The re-establishing of the integrity of the bone lesions could be a promising strategy in the treatment of accidental or surgery trauma, especially for cranial bones. ..
Libro R, Diomede F, Scionti D, Piattelli A, Grassi G, Pollastro F, et al
. Cannabidiol Modulates the Expression of Alzheimer's Disease-Related Genes in Mesenchymal Stem Cells. Int J Mol Sci. 2016;18: pubmed publisher
..Therefore, we suggested that GMSCs preconditioned with CBD possess a molecular profile that might be more beneficial for the treatment of AD. ..
Diomede F, Gugliandolo A, Scionti D, Merciaro I, Cavalcanti M, Mazzon E, et al
. Biotherapeutic Effect of Gingival Stem Cells Conditioned Medium in Bone Tissue Restoration. Int J Mol Sci. 2018;19: pubmed publisher
..Especially, hGMSCs derived CM played a key role in the induction of the osteogenic process and in bone regeneration. ..
Trubiani O, Giacoppo S, Ballerini P, Diomede F, Piattelli A, Bramanti P, et al
. Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis. Stem Cell Res Ther. 2016;7:1 pubmed publisher
..These cells could have considerable implication for future therapies for multiple sclerosis and this study may represent the starting point for further investigations. ..
Mazzoni S, Mohammadi S, Tromba G, Diomede F, Piattelli A, Trubiani O, et al
. Role of Cortico-Cancellous Heterologous Bone in Human Periodontal Ligament Stem Cell Xeno-Free Culture Studied by Synchrotron Radiation Phase-Contrast Microtomography. Int J Mol Sci. 2017;18: pubmed publisher