Affiliation: University of Chieti
Trubiani O, Fulle S, Traini T, Paludi M, La Rovere R, Orciani M, et al
. Functional assay, expression of growth factors and proteins modulating bone-arrangement in human osteoblasts seeded on an anorganic bovine bone biomaterial. Eur Cell Mater. 2010;20:72-83 pubmed
..These results encourage us to consider GBO an adequate biocompatible three-dimensional biomaterial, indicating its potential use for the development of tissue-engineering techniques. ..
Pizzicannella J, Cavalcanti M, Trubiani O, Diomede F. MicroRNA 210 Mediates VEGF Upregulation in Human Periodontal Ligament Stem Cells Cultured on 3DHydroxyapatite Ceramic Scaffold. Int J Mol Sci. 2018;19: pubmed publisher
Lanza Cariccio V, Scionti D, Raffa A, Iori R, Pollastro F, Diomede F, et al
. Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway. Int J Mol Sci. 2018;19: pubmed publisher
..In conclusion, hPDLSCs treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential. ..
Trubiani O, Recchioni R, Moroni F, Pizzicannella J, Caputi S, Di Primio R. Melatonin provokes cell death in human B-lymphoma cells by mitochondrial-dependent apoptotic pathway activation. J Pineal Res. 2005;39:425-31 pubmed
..Taken together, our study indicates that melatonin may play a role as potential therapeutic drug in specific lymphoproliferative diseases. ..
Trubiani O, Diomede F. Xeno-free culture of human periodontal ligament stem cells. Methods Mol Biol. 2015;1283:87-92 pubmed publisher
Diomede F, D Aurora M, Gugliandolo A, Merciaro I, Orsini T, Gatta V, et al
. Biofunctionalized Scaffold in Bone Tissue Repair. Int J Mol Sci. 2018;19: pubmed publisher
..These results suggest a promising potential application of CM from hPDLSCs and scaffolds for bone defect restoration and in particular for calvarial repair in case of trauma. ..
Diomede F, Gugliandolo A, Cardelli P, Merciaro I, Ettorre V, Traini T, et al
. Three-dimensional printed PLA scaffold and human gingival stem cell-derived extracellular vesicles: a new tool for bone defect repair. Stem Cell Res Ther. 2018;9:104 pubmed publisher
..The re-establishing of the integrity of the bone lesions could be a promising strategy in the treatment of accidental or surgery trauma, especially for cranial bones. ..
Libro R, Diomede F, Scionti D, Piattelli A, Grassi G, Pollastro F, et al
. Cannabidiol Modulates the Expression of Alzheimer's Disease-Related Genes in Mesenchymal Stem Cells. Int J Mol Sci. 2016;18: pubmed publisher
..Therefore, we suggested that GMSCs preconditioned with CBD possess a molecular profile that might be more beneficial for the treatment of AD. ..
Diomede F, Gugliandolo A, Scionti D, Merciaro I, Cavalcanti M, Mazzon E, et al
. Biotherapeutic Effect of Gingival Stem Cells Conditioned Medium in Bone Tissue Restoration. Int J Mol Sci. 2018;19: pubmed publisher
..Especially, hGMSCs derived CM played a key role in the induction of the osteogenic process and in bone regeneration. ..