M R Torrisi

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization
    M R Torrisi
    Dipartimento di Medicina Sperimentale e Patologia, University of Roma La Sapienza, Rome 00161, Italy
    Mol Biol Cell 10:417-34. 1999
  2. ncbi Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation
    L V Lotti
    Dipartimento di Medicina Sperimentale e Patologia, Universit a di Roma La Sapienza, Italy
    Mol Cell Biol 16:1946-54. 1996
  3. ncbi Intracellular transport and maturation pathway of human herpesvirus 6
    M R Torrisi
    Dipartimento di Medicina Sperimentale e Patologia, Universita di Roma La Sapienza, Rome, 00161, Italy
    Virology 257:460-71. 1999
  4. ncbi Fibroblast growth factor 10 induces proliferation and differentiation of human primary cultured keratinocytes
    C Marchese
    Dipartimento di Medicina Sperimentale e Patologia, Universita di Roma La Sapienza, Roma, Italy
    J Invest Dermatol 116:623-8. 2001
  5. ncbi Keratinocyte growth factor receptor (KGF-R) in cholesteatoma tissue
    M Barbara
    Department of Otorhinolaryngology, Sapienza University II Medical School, Rome, Italy
    Acta Otolaryngol 128:360-4. 2008
  6. ncbi Identification and characterization of the product encoded by ORF69 of Kaposi's sarcoma-associated herpesvirus
    R Santarelli
    Dipartimento di Medicina Sperimentale, Universita di Roma La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    J Virol 82:4562-72. 2008
  7. ncbi Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins
    M C Pascale
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano Salerno, Italy
    Exp Cell Res 291:377-85. 2003
  8. ncbi CD8(+) T lymphocytes induce polarized exocytosis of secretory lysosomes by dendritic cells with release of interleukin-1beta and cathepsin D
    S Gardella
    Unit of Protein Biology, Laboratory of Immunology, and Biotechnology Section of Roma, National Cancer Research Institute, 16132 Genoa, Italy
    Blood 98:2152-9. 2001
  9. ncbi Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain
    C Russo
    Laboratorio di Biologia Molecolare, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    J Biol Chem 276:19524-31. 2001
  10. ncbi eps15 and eps15R are essential components of the endocytic pathway
    R Carbone
    Department of Experimental Oncology, European Institute of Oncology, Milan, Italy
    Cancer Res 57:5498-504. 1997

Collaborators

  • B Falini
  • M Igarashi
  • M Cirone
  • R Gradini
  • A Poggi
  • A Faggioni
  • M Barbara
  • L Frati
  • R Santarelli
  • C Marchese
  • M C Pascale
  • L V Lotti
  • S Gardella
  • C Russo
  • F Belleudi
  • P Mancini
  • A Modesti
  • R Gonnella
  • M Granato
  • A Farina
  • S Raffa
  • R Bei
  • L Leone
  • R Carbone
  • A Leone
  • C Bucci
  • O Moltedo
  • P G Pelicci
  • S Franceschelli
  • S La Fontaine
  • J F B Mercer
  • Y Gao
  • A Rubartelli
  • M Falasca
  • Y Zheng
  • G Lucania
  • C Vanni
  • V Visco
  • A Felici
  • M R Zocchi
  • M Porotto
  • C Andrei
  • A Eva
  • M Picardo
  • D Guardavaccaro
  • C De Stefano
  • M Sorice
  • S Fre
  • G Iannolo
  • P P Di Fiore
  • E Migliaccio
  • C Zompetta
  • L Lanfrancone
  • A E Salcini
  • G Pelicci
  • A Gatti
  • M T Ciotti
  • L Lotti
  • F Tirone
  • A Montagnoli
  • C Di Lazzaro

Detail Information

Publications12

  1. ncbi Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization
    M R Torrisi
    Dipartimento di Medicina Sperimentale e Patologia, University of Roma La Sapienza, Rome 00161, Italy
    Mol Biol Cell 10:417-34. 1999
    ..Our results are consistent with a model in which eps15 undergoes cycles of association:dissociation with membranes and suggest multiple roles for this protein in the endocytic pathway...
  2. ncbi Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation
    L V Lotti
    Dipartimento di Medicina Sperimentale e Patologia, Universit a di Roma La Sapienza, Italy
    Mol Cell Biol 16:1946-54. 1996
    ....
  3. ncbi Intracellular transport and maturation pathway of human herpesvirus 6
    M R Torrisi
    Dipartimento di Medicina Sperimentale e Patologia, Universita di Roma La Sapienza, Rome, 00161, Italy
    Virology 257:460-71. 1999
    ..Pulse-chase analysis indicated degradation of the gp116, consistent with its endosomal localization and with the absence of viral glycoproteins on the cell surface of the infected cells...
  4. ncbi Fibroblast growth factor 10 induces proliferation and differentiation of human primary cultured keratinocytes
    C Marchese
    Dipartimento di Medicina Sperimentale e Patologia, Universita di Roma La Sapienza, Roma, Italy
    J Invest Dermatol 116:623-8. 2001
    ....
  5. ncbi Keratinocyte growth factor receptor (KGF-R) in cholesteatoma tissue
    M Barbara
    Department of Otorhinolaryngology, Sapienza University II Medical School, Rome, Italy
    Acta Otolaryngol 128:360-4. 2008
    ..Moreover, both EGF-R and KGF-R expression was increased, suggesting a fair correlation with aggressiveness and recurrence rate of this pathology...
  6. ncbi Identification and characterization of the product encoded by ORF69 of Kaposi's sarcoma-associated herpesvirus
    R Santarelli
    Dipartimento di Medicina Sperimentale, Universita di Roma La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    J Virol 82:4562-72. 2008
    ..The above results indicate that KSHV p33 shares many similarities with its EBV homolog BFLF2 and suggest that functional cross-complementation is possible between members of the gammaherpesvirus subfamily...
  7. ncbi Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins
    M C Pascale
    Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano Salerno, Italy
    Exp Cell Res 291:377-85. 2003
    ....
  8. ncbi CD8(+) T lymphocytes induce polarized exocytosis of secretory lysosomes by dendritic cells with release of interleukin-1beta and cathepsin D
    S Gardella
    Unit of Protein Biology, Laboratory of Immunology, and Biotechnology Section of Roma, National Cancer Research Institute, 16132 Genoa, Italy
    Blood 98:2152-9. 2001
    ..These events result in polarized exocytosis of secretory lysosomes, mediated by microtubules, with release of IL-1beta and cathepsin D toward the interacting CD8(+) T cell...
  9. ncbi Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain
    C Russo
    Laboratorio di Biologia Molecolare, Istituto G Gaslini, Largo G Gaslini 5, 16147 Genova, Italy
    J Biol Chem 276:19524-31. 2001
    ..These results suggest that modulation of PIPs in both the GEF catalytic activity and the targeting to plasma membrane determines the outcome of the biologic activity of Dbl...
  10. ncbi eps15 and eps15R are essential components of the endocytic pathway
    R Carbone
    Department of Experimental Oncology, European Institute of Oncology, Milan, Italy
    Cancer Res 57:5498-504. 1997
    ..These results demonstrate that eps15 and eps15R are essential components of the endocytic machinery...
  11. ncbi Modulation of keratinocyte growth factor receptor expression in human cultured keratinocytes
    C Marchese
    Istituto Nazionale Ricerca sul Cancro di Genova, Sezione di Biotecnologie, Rome, Italy
    Cell Growth Differ 8:989-97. 1997
    ..Our results suggest that the expression of KGFR, unlike that of the epidermal growth factor receptor, may control the proliferative-differentiative program from basal to suprabasal cells in human skin...
  12. ncbi Nerve growth factor regulates the subcellular localization of the nerve growth factor-inducible protein PC4 in PC12 cells
    D Guardavaccaro
    Istituto di Neurobiologia, Consiglio Nazionale delle Richerche, Rome, Italy
    J Neurosci Res 37:660-74. 1994
    ..For an NGF-inducible IEG product, such growth factor-dependent localization of PC4 is a novel type of regulation in the pathways from the NGF receptor to the adjacent membrane proteins and to the nucleus...