Research Topics
Species | C TibertiSummaryAffiliation: University of Rome La Sapienza Country: Italy Publications
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Detail Information
Publications
IA-2 combined epitope assay: a new, highly sensitive approach to evaluate IA-2 humoral autoimmunity in type 1 diabetesClaudio Tiberti
Department of Medical Sciences, Endocrinology, University of Rome La Sapienza, Italy
Clin Immunol 115:260-7. 2005..3% DM and 30.4% PDM subjects compared to the single IA-2 IC construct, suggesting this methodology as a new, highly sensitive approach to the study of IA-2 autoimmunity in type 1 diabetes...
GAD and IA-2 autoantibody detection in type 1 diabetic patient salivaClaudio Tiberti
Department of Clinical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
Clin Immunol 131:271-6. 2009....- Identification of tyrosine phosphatase 2(256-760) construct as a new, sensitive marker for the detection of islet autoimmunity in type 2 diabetic patients: the non-insulin requiring autoimmune diabetes (NIRAD) study 2Claudio Tiberti
Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
Diabetes 57:1276-83. 2008.... - Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivitiesC Tiberti
Dept of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy
Clin Immunol 121:40-6. 2006.... - Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependentC Tiberti
Department of Clinical Sciences, University La Sapienza, Rome, Italy
Clin Immunol 109:318-24. 2003..Our data identify a subset of CD patients showing a strong humoral tTG immunoreactivity at diagnosis, thus suggesting that age and sex influence the anti-tTG autoantibody response... 
Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screeningC Tiberti
Department of Clinical Sciences, University of Rome Sapienza, Rome, Italy
Clin Exp Immunol 166:317-24. 2011..It appears to be particularly appropriate as a first-line approach for large-scale population-based screenings of anti-islet autoimmunity...- Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-upM Bonamico
Department of Paediatrics, Sapienza University of Rome, Rome, Italy
Aliment Pharmacol Ther 28:364-70. 2008..Serum radioimmunoassay (RIA) tissue transglutaminase autoantibodies (tTG-Abs) proved to be a sensitive test also during coeliac disease (CD) follow-up. We demonstrated that RIA tTG-Abs could be detected in human saliva... - Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?C Tiberti
Department of Endocrinology, Clinica Medica 2, University La Sapienza, Rome, Italy
Diabetes Metab Res Rev 16:8-14. 2000..e. possibly referrable to as idiopathic Type 1b diabetes... - Radioimmunoassay to detect antitransglutaminase autoantibodies is the most sensitive and specific screening method for celiac diseaseM Bonamico
Istituto di Clinica Pediatrica, Dipartimento di Scienze Cliniche, Medicina Sperimentale e Patologia, , Rome, Italy
Am J Gastroenterol 96:1536-40. 2001..If our data are confirmed by studies on larger series, tissue transglutaminase RIA could be proposed as the best screening method for celiac patients... - Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetesE Anastasi
Endocrinology, Clinica Medica 2, University of Rome La Sapienza, Italy
Eur J Endocrinol 141:644-52. 1999..To evaluate the existence of beta-cell differentiation and proliferation in the low-dose streptozotocin (ld-STZ) mouse model of autoimmune diabetes... - Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5)S Zampetti
Department of Clinical Sciences, Sapienza University, Rome, Italy
Diabet Med 27:701-4. 2010..The aim of the present study was to evaluate whether the phenotypic heterogeneity of LADA based on GADA titre is associated with TCF7L2 polymorphisms... - Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled studySusanna Morano
Department of Clinical Sciences, Sapienza University, Rome, Italy
Eur Urol 52:1768-74. 2007..To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity and endothelial dysfunction markers in diabetic patients with erectile dysfunction (ED)... - Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relativesMargherita Bonamico
Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
J Pediatr Gastroenterol Nutr 42:150-4. 2006..The prevalence of celiac disease (CD) among the relatives and the complications of an undiagnosed CD prompted us to identify a useful disease screening strategy... - HLA-DQB1*02 dose effect on RIA anti-tissue transglutaminase autoantibody levels and clinicopathological expressivity of celiac diseaseRaffaella Nenna
Departments of Paediatrics, Sapienza University, Rome, Italy
J Pediatr Gastroenterol Nutr 47:288-92. 2008..Our aim was to investigate whether the DQB1*02 allele could influence tTGAb titers and the clinicopathological expressivity of the disease... - Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunctionSusanna Morano
Department of Clinical Sciences, University La Sapienza, Rome, Italy
J Urol 177:655-9. 2007..We investigated the relationship between oxidative stress and diabetic erectile dysfunction... - Tissue transglutaminase autoantibody detection in human saliva: a powerful method for celiac disease screeningMargherita Bonamico
Institute of Paediatrics and Department of Clinical Science, University of Rome La Sapienza, Italy
J Pediatr 144:632-6. 2004..To test the possibility of detecting tissue transglutaminase autoantibodies (tTG-Abs) in saliva with a novel sensitive fluid-phase radioimmunoassay (RIA)... - Patchy villous atrophy of the duodenum in childhood celiac diseaseMargherita Bonamico
Department of Pediatrics, University of Rome La Sapienza, Rome, Italy
J Pediatr Gastroenterol Nutr 38:204-7. 2004..The authors evaluated the presence and the distribution of villous atrophy in children with celiac disease to see whether this histologic pattern exists in children... - Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopesLoredana Farilla
Department of Medical Sciences, Endocrinology, University La Sapienza, Rome, Italy
Eur J Immunol 32:1420-7. 2002.... - The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3Antonio Petrone
Department of Clinical Science, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Rome, Italy
Diabetes Care 31:534-8. 2008..The aim of the present study was to evaluate whether the phenotypic heterogeneity of adult-onset autoimmune diabetes based on the GADA titer is associated with the PTPN22 C1858T polymorphism... - Insulin sensitivity assessment in uncomplicated obese women: comparison of indices from fasting and oral glucose load with euglycemic hyperinsulinemic clampF Leonetti
Endocrinology, Department of Clinical Sciences, University La Sapienza, Rome, Italy
Nutr Metab Cardiovasc Dis 14:366-72. 2004..Several formulae developed from measurements in the fasting state and during the oral glucose tolerance test (OGTT) have been proposed to assess insulin sensitivity... - Prevalence of type 1 diabetes autoantibodies (GADA, IA2, and IAA) in overweight and obese childrenValentina M Cambuli
Endocrinology and Diabetes, Department of Medical Sciences, University of Cagliari, Cagliari, Italy
Diabetes Care 33:820-2. 2010..The prevalence of type 1 diabetes autoantibodies and its relation with hyperglycemia was analyzed in 686 overweight/obese children and adolescents... - Acute insulin infusion decreases plasma ghrelin levels in uncomplicated obesityFrida Leonetti
Endocrinology, Department of Clinical Sciences, University La Sapienza, Rome, Italy
Regul Pept 122:179-83. 2004..05). CONCLUSIONS: Our data seem to suggest that hyperinsulinemia during a euglycemic clamp is able to suppress plasma ghrelin concentrations in uncomplicated obesity. This effect appears to be positively related to insulin sensitivity... - Different plasma ghrelin levels after laparoscopic gastric bypass and adjustable gastric banding in morbid obese subjectsFrida Leonetti
Division of Endocrinology, University La Sapienza, Rome, Italy 00161
J Clin Endocrinol Metab 88:4227-31. 2003..Significant difference in plasma ghrelin levels between LRYGBP and LASGB was found, suggesting that both procedures could induce weight loss by different mechanisms in which ghrelin could be involved... - Relationship of insulin sensitivity and left ventricular mass in uncomplicated obesityGianluca Iacobellis
Endocrinology Section, Department of Clinical Sciences, University La Sapienza, Rome, Italy
Obes Res 11:518-24. 2003..We studied uncomplicated obesity as a model to evaluate the influence of insulin sensitivity per se on left ventricular mass (LVM) and geometry... - The adiponectin gene SNP+276G>T associates with early-onset coronary artery disease and with lower levels of adiponectin in younger coronary artery disease patients (age <or=50 years)Emanuela Filippi
Department of Clinical Sciences, Division of Endocrinology, Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy
J Mol Med (Berl) 83:711-9. 2005.... - Slowly progressing type 1 diabetes: persistence of islet cell autoantibodies is related to glibenclamide treatmentEduardo Cabrera-Rode
Department of Immunology of Diabetes Mellitus, National Institute of Endocrinology, Vedado, Havana, Cuba
Autoimmunity 35:469-74. 2002..This phenomenon may be deleterious for the preservation of residual beta cell function in patients with slowly progressing type 1 diabetes or latent autoimmune diabetes of adult (LADA)... - Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetesEduardo Cabrera-Rode
Department of Immunology of Diabetes Mellitus, National Institute of Endocrinology, Zapata and D, Vedado, Havana, Cuba
Autoimmunity 39:333-40. 2006..Nicotinamide has been used with success to prevent type 1 diabetes in animal models and humans. This vitamin B3 derivative has attracting effects on beta-cell protection and regeneration... - ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodiesDongmei Miao
Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver 80262, USA
J Autoimmun 18:191-6. 2002.... - Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac diseaseEdwin Liu
Section of Gastroenterology, Hepatology and Nutrition, The Children s Hospital, and Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Denver, CO, USA
J Pediatr Gastroenterol Nutr 45:293-300. 2007..A new generation of anti-gliadin antibody assays has been developed to detect synthetic, deamidated homologous gliadin peptides (DGP) with high sensitivity and specificity... - Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiencyAlberto Falorni
Department of Internal Medicine, University of Perugia, 06126 Perugia, Italy
J Clin Endocrinol Metab 89:1598-604. 2004..Lastly, we developed a comprehensive flowchart for the classification of PAI for use in routine clinical practice... - Mapping of human autoantibody epitopes on aromatic L-amino acid decarboxylasePaola Candeloro
Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
J Clin Endocrinol Metab 92:1096-105. 2007..Little information is currently available on AADC autoantibody epitopes and on the interrelation between autoantibody-mediated inhibition of enzymatic activity and epitope specificity...