C Tiberti

Summary

Affiliation: University of Rome La Sapienza
Country: Italy

Publications

  1. ncbi request reprint IA-2 combined epitope assay: a new, highly sensitive approach to evaluate IA-2 humoral autoimmunity in type 1 diabetes
    Claudio Tiberti
    Department of Medical Sciences, Endocrinology, University of Rome La Sapienza, Italy
    Clin Immunol 115:260-7. 2005
  2. doi request reprint GAD and IA-2 autoantibody detection in type 1 diabetic patient saliva
    Claudio Tiberti
    Department of Clinical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
    Clin Immunol 131:271-6. 2009
  3. doi request reprint Identification of tyrosine phosphatase 2(256-760) construct as a new, sensitive marker for the detection of islet autoimmunity in type 2 diabetic patients: the non-insulin requiring autoimmune diabetes (NIRAD) study 2
    Claudio Tiberti
    Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Diabetes 57:1276-83. 2008
  4. ncbi request reprint Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivities
    C Tiberti
    Dept of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy
    Clin Immunol 121:40-6. 2006
  5. ncbi request reprint Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependent
    C Tiberti
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Clin Immunol 109:318-24. 2003
  6. pmc Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening
    C Tiberti
    Department of Clinical Sciences, University of Rome Sapienza, Rome, Italy
    Clin Exp Immunol 166:317-24. 2011
  7. ncbi request reprint Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-up
    M Bonamico
    Department of Paediatrics, Sapienza University of Rome, Rome, Italy
    Aliment Pharmacol Ther 28:364-70. 2008
  8. ncbi request reprint Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?
    C Tiberti
    Department of Endocrinology, Clinica Medica 2, University La Sapienza, Rome, Italy
    Diabetes Metab Res Rev 16:8-14. 2000
  9. ncbi request reprint Radioimmunoassay to detect antitransglutaminase autoantibodies is the most sensitive and specific screening method for celiac disease
    M Bonamico
    Istituto di Clinica Pediatrica, Dipartimento di Scienze Cliniche, Medicina Sperimentale e Patologia, , Rome, Italy
    Am J Gastroenterol 96:1536-40. 2001
  10. ncbi request reprint Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetes
    E Anastasi
    Endocrinology, Clinica Medica 2, University of Rome La Sapienza, Italy
    Eur J Endocrinol 141:644-52. 1999

Collaborators

Detail Information

Publications31

  1. ncbi request reprint IA-2 combined epitope assay: a new, highly sensitive approach to evaluate IA-2 humoral autoimmunity in type 1 diabetes
    Claudio Tiberti
    Department of Medical Sciences, Endocrinology, University of Rome La Sapienza, Italy
    Clin Immunol 115:260-7. 2005
    ..3% DM and 30.4% PDM subjects compared to the single IA-2 IC construct, suggesting this methodology as a new, highly sensitive approach to the study of IA-2 autoimmunity in type 1 diabetes...
  2. doi request reprint GAD and IA-2 autoantibody detection in type 1 diabetic patient saliva
    Claudio Tiberti
    Department of Clinical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
    Clin Immunol 131:271-6. 2009
    ....
  3. doi request reprint Identification of tyrosine phosphatase 2(256-760) construct as a new, sensitive marker for the detection of islet autoimmunity in type 2 diabetic patients: the non-insulin requiring autoimmune diabetes (NIRAD) study 2
    Claudio Tiberti
    Department of Clinical Sciences, University of Rome La Sapienza, Rome, Italy
    Diabetes 57:1276-83. 2008
    ....
  4. ncbi request reprint Evidence of a selective epitope loss of anti-transglutaminase immunoreactivity in gluten-free diet celiac sera: a new tool to distinguish disease-specific immunoreactivities
    C Tiberti
    Dept of Clinical Sciences, University of Rome La Sapienza, Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy
    Clin Immunol 121:40-6. 2006
    ....
  5. ncbi request reprint Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependent
    C Tiberti
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Clin Immunol 109:318-24. 2003
    ..Our data identify a subset of CD patients showing a strong humoral tTG immunoreactivity at diagnosis, thus suggesting that age and sex influence the anti-tTG autoantibody response...
  6. pmc Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening
    C Tiberti
    Department of Clinical Sciences, University of Rome Sapienza, Rome, Italy
    Clin Exp Immunol 166:317-24. 2011
    ..It appears to be particularly appropriate as a first-line approach for large-scale population-based screenings of anti-islet autoimmunity...
  7. ncbi request reprint Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-up
    M Bonamico
    Department of Paediatrics, Sapienza University of Rome, Rome, Italy
    Aliment Pharmacol Ther 28:364-70. 2008
    ..Serum radioimmunoassay (RIA) tissue transglutaminase autoantibodies (tTG-Abs) proved to be a sensitive test also during coeliac disease (CD) follow-up. We demonstrated that RIA tTG-Abs could be detected in human saliva...
  8. ncbi request reprint Autoantibody negative new onset type 1 diabetic patients lacking high risk HLA alleles in a caucasian population: are these type 1b diabetes cases?
    C Tiberti
    Department of Endocrinology, Clinica Medica 2, University La Sapienza, Rome, Italy
    Diabetes Metab Res Rev 16:8-14. 2000
    ..e. possibly referrable to as idiopathic Type 1b diabetes...
  9. ncbi request reprint Radioimmunoassay to detect antitransglutaminase autoantibodies is the most sensitive and specific screening method for celiac disease
    M Bonamico
    Istituto di Clinica Pediatrica, Dipartimento di Scienze Cliniche, Medicina Sperimentale e Patologia, , Rome, Italy
    Am J Gastroenterol 96:1536-40. 2001
    ..If our data are confirmed by studies on larger series, tissue transglutaminase RIA could be proposed as the best screening method for celiac patients...
  10. ncbi request reprint Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetes
    E Anastasi
    Endocrinology, Clinica Medica 2, University of Rome La Sapienza, Italy
    Eur J Endocrinol 141:644-52. 1999
    ..To evaluate the existence of beta-cell differentiation and proliferation in the low-dose streptozotocin (ld-STZ) mouse model of autoimmune diabetes...
  11. doi request reprint Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5)
    S Zampetti
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Diabet Med 27:701-4. 2010
    ..The aim of the present study was to evaluate whether the phenotypic heterogeneity of LADA based on GADA titre is associated with TCF7L2 polymorphisms...
  12. ncbi request reprint Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study
    Susanna Morano
    Department of Clinical Sciences, Sapienza University, Rome, Italy
    Eur Urol 52:1768-74. 2007
    ..To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity and endothelial dysfunction markers in diabetic patients with erectile dysfunction (ED)...
  13. ncbi request reprint Serologic and genetic markers of celiac disease: a sequential study in the screening of first degree relatives
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    J Pediatr Gastroenterol Nutr 42:150-4. 2006
    ..The prevalence of celiac disease (CD) among the relatives and the complications of an undiagnosed CD prompted us to identify a useful disease screening strategy...
  14. doi request reprint HLA-DQB1*02 dose effect on RIA anti-tissue transglutaminase autoantibody levels and clinicopathological expressivity of celiac disease
    Raffaella Nenna
    Departments of Paediatrics, Sapienza University, Rome, Italy
    J Pediatr Gastroenterol Nutr 47:288-92. 2008
    ..Our aim was to investigate whether the DQB1*02 allele could influence tTGAb titers and the clinicopathological expressivity of the disease...
  15. ncbi request reprint Circulating monocyte oxidative activity is increased in patients with type 2 diabetes and erectile dysfunction
    Susanna Morano
    Department of Clinical Sciences, University La Sapienza, Rome, Italy
    J Urol 177:655-9. 2007
    ..We investigated the relationship between oxidative stress and diabetic erectile dysfunction...
  16. ncbi request reprint Tissue transglutaminase autoantibody detection in human saliva: a powerful method for celiac disease screening
    Margherita Bonamico
    Institute of Paediatrics and Department of Clinical Science, University of Rome La Sapienza, Italy
    J Pediatr 144:632-6. 2004
    ..To test the possibility of detecting tissue transglutaminase autoantibodies (tTG-Abs) in saliva with a novel sensitive fluid-phase radioimmunoassay (RIA)...
  17. ncbi request reprint Patchy villous atrophy of the duodenum in childhood celiac disease
    Margherita Bonamico
    Department of Pediatrics, University of Rome La Sapienza, Rome, Italy
    J Pediatr Gastroenterol Nutr 38:204-7. 2004
    ..The authors evaluated the presence and the distribution of villous atrophy in children with celiac disease to see whether this histologic pattern exists in children...
  18. ncbi request reprint Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopes
    Loredana Farilla
    Department of Medical Sciences, Endocrinology, University La Sapienza, Rome, Italy
    Eur J Immunol 32:1420-7. 2002
    ....
  19. ncbi request reprint The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3
    Antonio Petrone
    Department of Clinical Science, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Rome, Italy
    Diabetes Care 31:534-8. 2008
    ..The aim of the present study was to evaluate whether the phenotypic heterogeneity of adult-onset autoimmune diabetes based on the GADA titer is associated with the PTPN22 C1858T polymorphism...
  20. ncbi request reprint Insulin sensitivity assessment in uncomplicated obese women: comparison of indices from fasting and oral glucose load with euglycemic hyperinsulinemic clamp
    F Leonetti
    Endocrinology, Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Nutr Metab Cardiovasc Dis 14:366-72. 2004
    ..Several formulae developed from measurements in the fasting state and during the oral glucose tolerance test (OGTT) have been proposed to assess insulin sensitivity...
  21. pmc Prevalence of type 1 diabetes autoantibodies (GADA, IA2, and IAA) in overweight and obese children
    Valentina M Cambuli
    Endocrinology and Diabetes, Department of Medical Sciences, University of Cagliari, Cagliari, Italy
    Diabetes Care 33:820-2. 2010
    ..The prevalence of type 1 diabetes autoantibodies and its relation with hyperglycemia was analyzed in 686 overweight/obese children and adolescents...
  22. ncbi request reprint Acute insulin infusion decreases plasma ghrelin levels in uncomplicated obesity
    Frida Leonetti
    Endocrinology, Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Regul Pept 122:179-83. 2004
    ..Nevertheless, the mechanism of the suggested inhibitory effect of insulin on ghrelin is still unclear and no data about the effect of acute insulin infusion on plasma ghrelin concentration in obese subjects are available...
  23. ncbi request reprint Different plasma ghrelin levels after laparoscopic gastric bypass and adjustable gastric banding in morbid obese subjects
    Frida Leonetti
    Division of Endocrinology, University La Sapienza, Rome, Italy 00161
    J Clin Endocrinol Metab 88:4227-31. 2003
    ..Significant difference in plasma ghrelin levels between LRYGBP and LASGB was found, suggesting that both procedures could induce weight loss by different mechanisms in which ghrelin could be involved...
  24. ncbi request reprint Relationship of insulin sensitivity and left ventricular mass in uncomplicated obesity
    Gianluca Iacobellis
    Endocrinology Section, Department of Clinical Sciences, University La Sapienza, Rome, Italy
    Obes Res 11:518-24. 2003
    ..We studied uncomplicated obesity as a model to evaluate the influence of insulin sensitivity per se on left ventricular mass (LVM) and geometry...
  25. ncbi request reprint The adiponectin gene SNP+276G>T associates with early-onset coronary artery disease and with lower levels of adiponectin in younger coronary artery disease patients (age <or=50 years)
    Emanuela Filippi
    Department of Clinical Sciences, Division of Endocrinology, Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy
    J Mol Med (Berl) 83:711-9. 2005
    ....
  26. ncbi request reprint Slowly progressing type 1 diabetes: persistence of islet cell autoantibodies is related to glibenclamide treatment
    Eduardo Cabrera-Rode
    Department of Immunology of Diabetes Mellitus, National Institute of Endocrinology, Vedado, Havana, Cuba
    Autoimmunity 35:469-74. 2002
    ..This phenomenon may be deleterious for the preservation of residual beta cell function in patients with slowly progressing type 1 diabetes or latent autoimmune diabetes of adult (LADA)...
  27. ncbi request reprint Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes
    Eduardo Cabrera-Rode
    Department of Immunology of Diabetes Mellitus, National Institute of Endocrinology, Zapata and D, Vedado, Havana, Cuba
    Autoimmunity 39:333-40. 2006
    ..Nicotinamide has been used with success to prevent type 1 diabetes in animal models and humans. This vitamin B3 derivative has attracting effects on beta-cell protection and regeneration...
  28. ncbi request reprint ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies
    Dongmei Miao
    Barbara Davis Center for Childhood Diabetes, University of Colorado, Denver 80262, USA
    J Autoimmun 18:191-6. 2002
    ....
  29. ncbi request reprint Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease
    Edwin Liu
    Section of Gastroenterology, Hepatology and Nutrition, The Children s Hospital, and Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Denver, CO, USA
    J Pediatr Gastroenterol Nutr 45:293-300. 2007
    ..A new generation of anti-gliadin antibody assays has been developed to detect synthetic, deamidated homologous gliadin peptides (DGP) with high sensitivity and specificity...
  30. ncbi request reprint Italian addison network study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency
    Alberto Falorni
    Department of Internal Medicine, University of Perugia, 06126 Perugia, Italy
    J Clin Endocrinol Metab 89:1598-604. 2004
    ..Lastly, we developed a comprehensive flowchart for the classification of PAI for use in routine clinical practice...
  31. ncbi request reprint Mapping of human autoantibody epitopes on aromatic L-amino acid decarboxylase
    Paola Candeloro
    Department of Internal Medicine, Section of Internal Medicine and Endocrine and Metabolic Sciences, Via E dal Pozzo, 06126 Perugia, Italy
    J Clin Endocrinol Metab 92:1096-105. 2007
    ..Little information is currently available on AADC autoantibody epitopes and on the interrelation between autoantibody-mediated inhibition of enzymatic activity and epitope specificity...